| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John W Hadde. Immunodeficiency and cancer: prospects for correction. International immunopharmacology. vol 3. issue 8. 2004-03-29. PMID:12860163. |
in studies of combination immunotherapy in lymphocytopenic squamous cell head and neck cancer patients using irx-2 (18 patients) and irx-2 plus thymosin alpha(1) (irx-3) in irx-2-refractory patients (7 patients), marked increases in cd(45)ra(+) 'naïve' t cells (>250/mm(3)) were observed. |
2004-03-29 |
2023-08-12 |
mouse |
| William Hornebeck, François Xavier Maquar. Proteolyzed matrix as a template for the regulation of tumor progression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 57. issue 5-6. 2004-03-29. PMID:12888258. |
mmp-2 and mt1-mmp, associated with tissue inhibitor of metalloprotease-2 (timp-2) and integrin (alpha(v)beta(3)) or cd(44), is mainly involved in such invasive program. |
2004-03-29 |
2023-08-12 |
Not clear |
| Egidio Giorgio, Camilla Minichino, Rosario G Viglione, Riccardo Zanasi, Carlo Rosin. Assignment of the molecular absolute configuration through the ab initio Hartree-Fock calculation of the optical rotation: can the circular dichroism data help in reducing basis set requirements? The Journal of organic chemistry. vol 68. issue 13. 2004-02-10. PMID:12816475. |
calculations on test molecules (compounds 1-13) together with a careful analysis of their cd spectra allow a simple criterion for the reliability of this approach to be formulated: for unsaturated and/or aromatic (i.e., absorbing in the near-uv region) molecules, if the [alpha](d) is quantitatively determined by the lowest energy cotton effect (at wavelengths >220 nm), then the hf/6-31g result is reliable. |
2004-02-10 |
2023-08-12 |
Not clear |
| Seung-Ki Kim, Kyu-Chang Wang, Soo Jin Hong, Chun-Kee Chung, Su-Young Lim, Young-Yim Kim, Je G Chi, Chong Jai Kim, You-Nam Chung, Hyun Jib Kim, Byung-Kyu Ch. Gene expression profile analyses of cortical dysplasia by cDNA arrays. Epilepsy research. vol 56. issue 2-3. 2004-01-20. PMID:14643002. |
three genes (recombination activating gene 1 (rag1), heat shock 60 kda protein 1 (hsp-60), and transforming growth factor beta1 (tgf beta1)) were found to be up-regulated more than two-fold in cd, whereas four genes (phosphoinositide-3-kinase regulatory subunit polypeptide 1 [p85 alpha] (pi3k), frizzled homolog 2 [drosophila], bcl-2/adenovirus e1b 19 kda interacting protein (nip3), and glia maturation factor beta (gmf beta)) were down-regulated to less than 50% of their normal levels. |
2004-01-20 |
2023-08-12 |
drosophila_melanogaster |
| Jarosław Poznański, Krystyna Bolewska, Igor Zhukov, Kazimierz L Wierzchowsk. Characterization of the low pH solution structure and dynamics of the region 4 of Escherichia coli RNA polymerase sigma70 subunit. Biochemistry. vol 42. issue 46. 2004-01-06. PMID:14621989. |
both analysis of cd spectra and nmr observables (secondary chemical shifts of the (13)calpha, (13)co, and (1)halpha nuclei and of vicinal (3)j(hnh)(alpha) coupling constants) indicated that a significant amount of helical structure remained in the protonated protein. |
2004-01-06 |
2023-08-12 |
Not clear |
| Toranosuke Tobita, Masayuki Oda, Hisayuki Morii, Masataka Kuroda, Atsuko Yoshino, Takachika Azuma, Haruo Kozon. A role for the P1 anchor residue in the thermal stability of MHC class II molecule I-Ab. Immunology letters. vol 85. issue 1. 2003-12-10. PMID:12505196. |
the thermal stability of the murine mhc class ii molecule, i-a(b), in complex with invariant chain-derived peptide (clip) and an antigenic peptide derived from the alpha subunit of the i-e molecule (ealpha) at mildly acidic and neutral ph were analyzed using circular dichroism (cd). |
2003-12-10 |
2023-08-12 |
Not clear |
| Jan Wehkamp, Juergen Harder, Michael Weichenthal, Oliver Mueller, Klaus R Herrlinger, Klaus Fellermann, Jens M Schroeder, Eduard F Stang. Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis. Inflammatory bowel diseases. vol 9. issue 4. 2003-10-28. PMID:12902844. |
expression of hbd-2 showed a weak correlation with interleukin 8 only in inflamed cd biopsies but not with tumor necrosis factor alpha. |
2003-10-28 |
2023-08-12 |
human |
| Sebastiaan Luyssaert, Jan Mertens, Hannu Raiti. Support, shape and number of replicate samples for tree foliage analysis. Journal of environmental monitoring : JEM. vol 5. issue 3. 2003-10-27. PMID:12833995. |
in terms of time, the optimal support to test whether the average cd concentration of the crown exceeds a threshold value is 0.405 m3 (alpha = 0.05, beta = 0.20, es = 1.0 mg kg(-1) dry mass). |
2003-10-27 |
2023-08-12 |
Not clear |
| Akhila Regunathan, David A Glesne, Allison K Wilson, Jongwoo Song, Dan Nicolae, Tony Flores, Maryka H Bhattacharyy. Microarray analysis of changes in bone cell gene expression early after cadmium gavage in mice. Toxicology and applied pharmacology. vol 191. issue 3. 2003-10-14. PMID:13678660. |
vacuolar proton pump atpase and integrin alpha v (osteoclast genes), transferrin receptor, and src-like adaptor protein genes were stimulated by cd; other src-related genes were unaffected. |
2003-10-14 |
2023-08-12 |
mouse |
| Isabelle Rubera, Johannes Loffing, Lawrence G Palmer, Gustavo Frindt, Nicole Fowler-Jaeger, Daniel Sauter, Tom Carroll, Andrew McMahon, Edith Hummler, Bernard C Rossie. Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. The Journal of clinical investigation. vol 112. issue 4. 2003-09-24. PMID:12925696. |
we have tested this hypothesis by inactivating the alpha subunit of enac in the cd but leaving enac expression in the late dct and cnt intact. |
2003-09-24 |
2023-08-12 |
mouse |
| H Yamini Shrivastava, Balachandran U Nai. Structural modification and aggregation of mucin by chromium(III) complexes. Journal of biomolecular structure & dynamics. vol 20. issue 4. 2003-09-16. PMID:12529156. |
a significant change in cd spectrum of pgm was observed in the presence of complex 2, where random coil spectrum became typical of a alpha-helical structure with 80% alpha helix content. |
2003-09-16 |
2023-08-12 |
Not clear |
| Agnes Vatay, László Bene, Agota Kovács, Zoltán Prohászka, Csaba Szalai, László Romics, Béla Fekete, István Karádi, George Füs. Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. Immunogenetics. vol 55. issue 4. 2003-09-11. PMID:12811429. |
the aim of the study was to determine the prevalence of the tumor necrosis factor alpha (tnf-alpha) promoter polymorphisms at positions -238 and -308, and to measure the serum crp levels in cd and uc patients and in a healthy population. |
2003-09-11 |
2023-08-12 |
human |
| Marco Marini, Giorgos Bamias, Jesús Rivera-Nieves, Christopher A Moskaluk, Sharon B Hoang, William G Ross, Theresa T Pizarro, Fabio Cominell. TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 14. 2003-09-04. PMID:12832622. |
tumor necrosis factor alpha (tnf-alpha) is an important mediator of programmed cell death, and tnf-alpha blockade significantly improves disease severity in several inflammatory conditions, including crohn's disease (cd), one of the idiopathic inflammatory bowel diseases. |
2003-09-04 |
2023-08-12 |
mouse |
| J Moriguchi, T Ezaki, T Tsukahara, K Furuki, Y Fukui, S Okamoto, H Ukai, H Sakurai, S Shimbo, M Iked. Comparative evaluation of four urinary tubular dysfunction markers, with special references to the effects of aging and correction for creatinine concentration. Toxicology letters. vol 143. issue 3. 2003-08-19. PMID:12849688. |
comparative evaluation was made on alpha(1)-microglobulin (alpha(1)-mg), beta(2)-microglobulin (beta(2)-mg), retinol binding protein (rbp) and n-acetyl-beta-d-glucosaminidase (nag), as a marker of renal tubular dysfunction after environmental exposure to cadmium (cd), with special references to the effects of aging and correction for creatinine concentration. |
2003-08-19 |
2023-08-12 |
Not clear |
| J Moriguchi, T Ezaki, T Tsukahara, K Furuki, Y Fukui, S Okamoto, H Ukai, H Sakurai, S Shimbo, M Iked. Comparative evaluation of four urinary tubular dysfunction markers, with special references to the effects of aging and correction for creatinine concentration. Toxicology letters. vol 143. issue 3. 2003-08-19. PMID:12849688. |
among the four tubular dysfunction markers, nag showed the closest correlation with cd, followed by alpha(1)-mg and then beta(2)-mg, and rbp was least so although the correlations were all statistically significant. |
2003-08-19 |
2023-08-12 |
Not clear |
| Sheena M Whyte, Ian D Sylvester, Stephen R Martin, Andrew C Gill, Franziska Wopfner, Hermann M Schätzl, Guy G Dodson, Peter M Bayle. Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. The Biochemical journal. vol 373. issue Pt 2. 2003-08-15. PMID:12665426. |
unfolding studies of doppel and the mutant have been performed using far-uv cd over a range of solution conditions known to favour the alpha-->beta transformation of recombinant prion protein. |
2003-08-15 |
2023-08-12 |
Not clear |
| Nicholas M Krohn, Christian Stemmer, Peter Fojan, Rudi Grimm, Klaus D Grasse. Protein kinase CK2 phosphorylates the high mobility group domain protein SSRP1, inducing the recognition of UV-damaged DNA. The Journal of biological chemistry. vol 278. issue 15. 2003-07-03. PMID:12571244. |
circular dichroism showed that the phosphorylation of the two c-terminal sites by ck2 alpha resulted in a structural change in the region of hmg box domain, because the negative peak of the cd spectrum at 222 nm was decreased by approximately 10%. |
2003-07-03 |
2023-08-12 |
Not clear |
| Miguel Regueiro, Houssam Mardin. Treatment of perianal fistulizing Crohn's disease with infliximab alone or as an adjunct to exam under anesthesia with seton placement. Inflammatory bowel diseases. vol 9. issue 2. 2003-06-26. PMID:12769443. |
infliximab, a chimeric monoclonal antibody targeting human tumor necrosis factor alpha (tnf), is approved for the treatment of fistulizing cd. |
2003-06-26 |
2023-08-12 |
human |
| Hiroto Nakadaira, Shinichi Nish. Effects of low-dose cadmium exposure on biological examinations. The Science of the total environment. vol 308. issue 1-3. 2003-06-24. PMID:12738200. |
in urine analysis, as indicators of cd exposure and possible related renal dysfunction, cd, beta(2)-microglobulin (beta(2)-mg), alpha(1)-microglobulin (alpha(1)-mg), n-acetyl-beta-d-glucosaminidase (nag), total protein, inorganic phosphorus, lysozyme and creatinine were quantitatively measured. |
2003-06-24 |
2023-08-12 |
human |
| Hiroto Nakadaira, Shinichi Nish. Effects of low-dose cadmium exposure on biological examinations. The Science of the total environment. vol 308. issue 1-3. 2003-06-24. PMID:12738200. |
in correlation analysis, beta(2)-mg, alpha(1)-mg and nag, were positively correlated with both of urinary and whole blood cd for men and women in the polluted area except for between urinary beta(2)-mg and urinary cd for men. |
2003-06-24 |
2023-08-12 |
human |