| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael T Henzl, Sayeh Agah, John D Larso. Rat alpha- and beta-parvalbumins: comparison of their pentacarboxylate and site-interconversion variants. Biochemistry. vol 43. issue 29. 2004-09-20. PMID:15260474. |
whereas the d59e mutation has minimal influence on beta cd site affinity, e59d has a major impact on the alpha cd site, lowering the apparent association constant by a factor of 14. |
2004-09-20 |
2023-08-12 |
rat |
| Michael T Henzl, Sayeh Agah, John D Larso. Rat alpha- and beta-parvalbumins: comparison of their pentacarboxylate and site-interconversion variants. Biochemistry. vol 43. issue 29. 2004-09-20. PMID:15260474. |
the thermodynamic consequences of exchanging the rat alpha cd and ef site ligand arrays, which differ at the +z and -x coordination positions, were also examined. |
2004-09-20 |
2023-08-12 |
rat |
| Michael T Henzl, Sayeh Agah, John D Larso. Rat alpha- and beta-parvalbumins: comparison of their pentacarboxylate and site-interconversion variants. Biochemistry. vol 43. issue 29. 2004-09-20. PMID:15260474. |
when the alpha cd array is imported into the ef site, it acquires a low-affinity phenotype, in agreement with previous findings for beta [henzl et al. |
2004-09-20 |
2023-08-12 |
rat |
| Michael T Henzl, Sayeh Agah, John D Larso. Rat alpha- and beta-parvalbumins: comparison of their pentacarboxylate and site-interconversion variants. Biochemistry. vol 43. issue 29. 2004-09-20. PMID:15260474. |
however, when the ef ligand array is introduced into the alpha cd binding loop, it retains a high-affinity signature. |
2004-09-20 |
2023-08-12 |
rat |
| Michael T Henzl, Sayeh Agah, John D Larso. Rat alpha- and beta-parvalbumins: comparison of their pentacarboxylate and site-interconversion variants. Biochemistry. vol 43. issue 29. 2004-09-20. PMID:15260474. |
this result, contrary to that observed in beta, suggests that the influence of the parvalbumin cd site environment supersedes the intrinsic behavior of the ligand array, a conclusion further supported by the disparate impact of the beta d59e and alpha e59d mutations. |
2004-09-20 |
2023-08-12 |
rat |
| Nicolas Fischer, Lutz Riechmann, Greg Winte. A native-like artificial protein from antisense DNA. Protein engineering, design & selection : PEDS. vol 17. issue 1. 2004-09-09. PMID:14985533. |
one of these, 2a6, was readily expressed in the escherichia coli cytoplasm as a soluble and protease-resistant protein and could be purified after heating the bacterial lysate to 90 degrees c. soluble 2a6 is dimeric and its cd spectrum is consistent with components of both alpha and beta structure. |
2004-09-09 |
2023-08-12 |
human |
| Sharon E Hook, Richard F Le. Interactive effects of UV, benzo[alpha] pyrene, and cadmium on DNA damage and repair in embryos of the grass shrimp Paleomonetes pugio. Marine environmental research. vol 58. issue 2-5. 2004-08-30. PMID:15178107. |
we examined the link between dna strand breaks and hatching rates in grass shrimp, (paleomonetes pugio), embryos exposed to 0.2 microm benzo[alpha] pyrene (bp), 5 microm cadmium (cd) and 330 kj/m(2) uv light, either alone or together. |
2004-08-30 |
2023-08-12 |
Not clear |
| Yayoi Jin, Hiroshi Sakurai, Yukifumi Nagai, Masako Naga. Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding: a study of mutants at alpha 42, alpha 140, beta 145 tyrosine or beta 37 tryptophan. Biopolymers. vol 74. issue 1-2. 2004-07-20. PMID:15137095. |
changes of near-uv cd spectrum of human hemoglobin upon oxygen binding: a study of mutants at alpha 42, alpha 140, beta 145 tyrosine or beta 37 tryptophan. |
2004-07-20 |
2023-08-12 |
human |
| Yayoi Jin, Hiroshi Sakurai, Yukifumi Nagai, Masako Naga. Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding: a study of mutants at alpha 42, alpha 140, beta 145 tyrosine or beta 37 tryptophan. Biopolymers. vol 74. issue 1-2. 2004-07-20. PMID:15137095. |
it has been suggested that the negative cd band is due to the environmental alteration of tyr-alpha 42 or trp-beta 37 at the alpha(1)beta(2) contact upon deoxygenation. |
2004-07-20 |
2023-08-12 |
human |
| Yayoi Jin, Hiroshi Sakurai, Yukifumi Nagai, Masako Naga. Changes of near-UV CD spectrum of human hemoglobin upon oxygen binding: a study of mutants at alpha 42, alpha 140, beta 145 tyrosine or beta 37 tryptophan. Biopolymers. vol 74. issue 1-2. 2004-07-20. PMID:15137095. |
to evaluate the contributions of the aromatic residues at the alpha(1)beta(2) contact and the penultimate tyrosine residues of the alpha and beta subunits (alpha 140 and beta 145) to the negative cd band, three recombinant (r) hbs (rhb ser-alpha 42, rhb his-beta 37, and rhb thr-beta 145) were produced in escherichia coli, and we compared the near-uv cd spectra of these three rhbs and hb rouen (tyr-alpha 140-->his) with the spectra of hb a under the condition in which all mutant hbs were able to undergo the t-->r transition (hill's n > 2.0). |
2004-07-20 |
2023-08-12 |
human |
| Yumei Huang, Subhakar Dey, Xiao Zhang, Frank Sönnichsen, Philip Garne. The alpha-helical peptide nucleic acid concept: merger of peptide secondary structure and codified nucleic acid recognition. Journal of the American Chemical Society. vol 126. issue 14. 2004-06-29. PMID:15070379. |
hybridization of these alpha pnas with ssdna has been examined by thermal denaturation, gel electrophoresis, and circular dichroism (cd) and the data indicated that alpha pna binds to ssdna in a cooperative manner with high affinity and sequence specificity. |
2004-06-29 |
2023-08-12 |
Not clear |
| David Gunnarsson, Mona Svensson, Gunnar Selstam, Gunnar Nordber. Pronounced induction of testicular PGF(2 alpha) and suppression of testosterone by cadmium-prevention by zinc. Toxicology. vol 200. issue 1. 2004-06-29. PMID:15158563. |
in order to investigate the effects of cadmium (cd) on testicular prostaglandin f(2 alpha) (pgf(2 alpha)) production, adult male sprague-dawley rats were exposed to cdcl(2) by subcutaneous injections. |
2004-06-29 |
2023-08-12 |
rat |
| Ralf Maye. Five biflavonoids from Calycopteris floribunda (Combretaceae). Phytochemistry. vol 65. issue 5. 2004-06-01. PMID:15003423. |
the structures of five biflavonoids, 6"-demethoxyneocalycopterone (1), calyflorenone c (2), 6"-epi-calyflorenone b (3), 6"-epi-calyflorenone c (4) and calyflorenone d (5) from the green parts of calycopteris floribunda were established by nmr and ms. their nmr and chiroptical properties (cd, [alpha]20d ) were compared with those of the known c. f. biflavonoids 6-11. |
2004-06-01 |
2023-08-12 |
Not clear |
| Ulrich Kortz, Saritha Nellutla, Ashley C Stowe, Naresh S Dalal, Urs Rauwald, Welbeck Danquah, Didier Ravo. Sandwich-type germanotungstates: structure and magnetic properties of the dimeric polyoxoanions [M4(H2O)2(GeW9O34)2]12 - (M = Mn2+, Cu2+, Zn2+, Cd2+). Inorganic chemistry. vol 43. issue 7. 2004-05-27. PMID:15046506. |
x-ray single-crystal analyses were carried out on na(12)[mn(4)(h(2)o)(2)(gew(9)o(34))(2)].38h(2)o (na(12)()-1), which crystallizes in the monoclinic system, space group p2(1)/n, with a = 13.0419(8) a, b = 17.8422(10) a, c = 21.1626(12) a, beta = 93.3120(10) degrees, and z = 2; na(11)cs(2)[cu(4)(h(2)o)(2)(gew(9)o(34))(2)]cl.31h(2)o (na(11)()cs-2) crystallizes in the triclinic system, space group p, with a = 12.2338(17) a, b = 12.3833(17) a, c = 15.449(2) a, alpha = 100.041(2) degrees, beta = 97.034(2) degrees, gamma = 101.153(2) degrees, and z = 1; na(12)[zn(4)(h(2)o)(2)(gew(9)o(34))(2)].32h(2)o (na(12)()-3) crystallizes in the triclinic system, space group p, with a = 11.589(3) a, b = 12.811(3) a, c = 17.221(4) a, alpha = 97.828(6) degrees, beta = 106.169(6) degrees, gamma = 112.113(5) degrees, and z = 1; na(12)[cd(4)(h(2)o)(2)(gew(9)o(34))(2)].32.2h(2)o (na(12)()-4) crystallizes also in the triclinic system, space group p, with a = 11.6923(17) a, b = 12.8464(18) a, c = 17.616(2) a, alpha = 98.149(3) degrees, beta = 105.677(3) degrees, gamma = 112.233(2) degrees, and z = 1. |
2004-05-27 |
2023-08-12 |
Not clear |
| Piotr Ruchala, Gyorgyi Varadi, Tetsuya Ishino, Jeffery Scibek, Madhushree Bhattacharya, Cecilia Urbina, Donald Van Ryk, Iain Uings, Irwin Chaike. Cyclic peptide interleukin 5 antagonists mimic CD turn recognition epitope for receptor alpha. Biopolymers. vol 73. issue 5. 2004-05-21. PMID:15048779. |
cyclic peptide interleukin 5 antagonists mimic cd turn recognition epitope for receptor alpha. |
2004-05-21 |
2023-08-12 |
human |
| Piotr Ruchala, Gyorgyi Varadi, Tetsuya Ishino, Jeffery Scibek, Madhushree Bhattacharya, Cecilia Urbina, Donald Van Ryk, Iain Uings, Irwin Chaike. Cyclic peptide interleukin 5 antagonists mimic CD turn recognition epitope for receptor alpha. Biopolymers. vol 73. issue 5. 2004-05-21. PMID:15048779. |
these results argue that af17121 and related library-derived peptides function by mimicking the cd turn receptor alpha recognition epitope in il-5 and open the way to small molecule antagonist design. |
2004-05-21 |
2023-08-12 |
human |
| Makoto Ohshima, Takehito Morita, Masumi Sawada, Akinori Shimada, Hideko Kobayashi, Kou Sawashim. B-cell immunoblastic lymphoma with multinucleated giant cells in a cat. The Journal of veterinary medical science. vol 66. issue 2. 2004-05-19. PMID:15031548. |
immunohistochemically, the neoplastic cells were positive for both b-cell antigen receptor complex (cd 79 alpha cy) and mhc class ii, although multinucleated giant cells were negative. |
2004-05-19 |
2023-08-12 |
cat |
| Gabriela Roa, M T Ramírez-Silva, M A Romero-Romo, Laura Galici. Determination of lead and cadmium using a polycyclodextrin-modified carbon paste electrode with anodic stripping voltammetry. Analytical and bioanalytical chemistry. vol 377. issue 4. 2004-05-11. PMID:12879186. |
this work reports the use of alpha and beta-cyclodextrin-modified carbon paste electrodes (cpe(alpha-cd) and cpe(beta-cd)) to determine simultaneously pb(ii) and cd(ii) by means of the electrochemical technique known as anodic stripping voltammetry (asv). |
2004-05-11 |
2023-08-12 |
Not clear |
| Wen-Lin Lai, Lien-Yang Chou, Chun-Yu Ting, Ralph Kirby, Ying-Chieh Tsai, Andrew H-J Wang, Shwu-Huey Lia. The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation. The Journal of biological chemistry. vol 279. issue 14. 2004-05-11. PMID:14736882. |
crystal structures of these metal derivatives show that zn(2+) and cd(2+) bind at the alpha(1) subsite ligated by his(67), his(69), and asp(366), while cu(2+) at the alpha(2) subsite is chelated by his(67), his(69) and cys(96). |
2004-05-11 |
2023-08-12 |
Not clear |
| Wolfgang Miehsler, Walter Reinisch, Lili Kazemi-Shirazi, Clemens Dejaco, Gottfried Novacek, Peter Ferenci, Friedrich Herbst, Judith Karner, Béla Téleky, Ewald Schober, Harald Vogelsan. Infliximab: lack of efficacy on perforating complications in Crohn's disease. Inflammatory bowel diseases. vol 10. issue 1. 2004-05-07. PMID:15058525. |
infliximab (remicade), a chimeric monoclonal antibody against tumor necrosis factor alpha (tnf-alpha), has emerged as promising therapeutic option in perianal fistulizing crohn's disease (cd). |
2004-05-07 |
2023-08-12 |
Not clear |