| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adeyinka Adeniyi, Sandra Abadir, Mohammed Kooshkabadi, Sunday O Yusuf, Radhika Khanna, Biagio Collura, Marie Anais Hichar. Recreational Marijuana Use and Coronary Artery Dissection: A Case Series. Cureus. vol 14. issue 1. 2022-03-07. PMID:35251848. |
the cardiovascular effects of marijuana have been shown to be a result of the activation of the cb1 and cb2 receptors located in the myocardium and coronary vasculatures. |
2022-03-07 |
2023-08-13 |
Not clear |
| Jiangling Peng, Mingjie Fan, Chelsea An, Feng Ni, Wendong Huang, Jiankang Lu. A narrative review of molecular mechanism and therapeutic effect of Cannabidiol (CBD). Basic & clinical pharmacology & toxicology. 2022-01-27. PMID:35083862. |
cannabidiol (cbd) is an abundant non-psychoactive phytocannabinoid in cannabis extracts which has high affinity on a series of receptors, including type 1 cannabinoid receptor (cb1), type 2 cannabinoid receptor (cb2), gpr55, transient receptor potential vanilloid (trpv), and peroxisome proliferator-activated receptor gamma (pparγ). |
2022-01-27 |
2023-08-13 |
human |
| Jiayi Yuan, Chen Jiang, Junmei Wang, Chih-Jung Chen, Yixuan Hao, Guangyi Zhao, Zhiwei Feng, Xiang-Qun Xi. In Silico Prediction and Validation of CB2 Allosteric Binding Sites to Aid the Design of Allosteric Modulators. Molecules (Basel, Switzerland). vol 27. issue 2. 2022-01-21. PMID:35056767. |
applying our novel algorithm toolset-mccs, we docked three known ams of cb2 including ec2la (c-2), trans-β-caryophyllene (tbc) and cannabidiol (cbd) to each site for further comparisons and quantified the potential binding residues in each allosteric binding site. |
2022-01-21 |
2023-08-13 |
Not clear |
| Mohammadali Amini, Zohreh Abdolmalek. The Effect of Cannabidiol Coated by Nano-Chitosan on Learning and Memory, Hippocampal CB1 and CB2 Levels, and Amyloid Plaques in an Alzheimer's Disease Rat Model. Neuropsychobiology. 2021-11-02. PMID:34727550. |
the effect of cannabidiol coated by nano-chitosan on learning and memory, hippocampal cb1 and cb2 levels, and amyloid plaques in an alzheimer's disease rat model. |
2021-11-02 |
2023-08-13 |
rat |
| Mohammadali Amini, Zohreh Abdolmalek. The Effect of Cannabidiol Coated by Nano-Chitosan on Learning and Memory, Hippocampal CB1 and CB2 Levels, and Amyloid Plaques in an Alzheimer's Disease Rat Model. Neuropsychobiology. 2021-11-02. PMID:34727550. |
therefore, the aim of this study was consideration of the effect of cannabidiol (cbd) coated by nano-chitosan on learning and memory, hippocampal cannabinoid receptor type 1 (cb1) and cannabinoid receptor type 1 (cb2) levels, and amyloid plaques in an ad rat model. |
2021-11-02 |
2023-08-13 |
rat |
| Waleed Hassan Almalk. A study of abnormal cannabidiols system-mediated cardiovascular protection in disrupted gut/brain axis associated depression. Journal of biochemical and molecular toxicology. 2021-10-22. PMID:34676637. |
the cardiovascular effects of tetrahydrocannabinol (thc) (the key psychotropic credential of cannabis) and endocannabinoids (thc endogenous equivalents which cause type 1 [cb1] and 2 [cb2] cannabinoids) have been extensively examined based on well-documented effects of marijuana smoke on blood pressure (bp) and heart rate (hr). |
2021-10-22 |
2023-08-13 |
Not clear |
| Lawrence Cohen, Manuela G Neuma. Cannabis and the Gastrointestinal Tract. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. vol 23. 2021-09-27. PMID:32762830. |
its consumption leads to the activation of cannabis receptors cb1 and cb2 that, through specific mechanisms can lead to modulation and progression of inflammation or repair. |
2021-09-27 |
2023-08-13 |
Not clear |
| Si-Jing Hu, Chen-Xia Lian, Tao Yu, Qi Zahng, Quan-Long Zhang, Qiao-Yan Zhang, Lu-Ping Qi. [Research progress on natural cannabinoid receptor type 2( CB2R)regulators and their effects on bone metabolism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 14. 2021-08-18. PMID:34402276. |
cannabinoids in cannabis sativa can cause psychoactive effects despite various pharmacological actions they exerted by targeting cb2 r. therefore,it is of great significance to discover cb2 r regulators in non-cannabis plants for finding new lead compounds without psychoactive effects and elucidating the action mechanism of plant drugs. |
2021-08-18 |
2023-08-13 |
Not clear |
| Valeria Giorgi, Daniela Marotto, Alberto Batticciotto, Fabiola Atzeni, Sara Bongiovanni, Piercarlo Sarzi-Puttin. Cannabis and Autoimmunity: Possible Mechanisms of Action. ImmunoTargets and therapy. vol 10. 2021-07-30. PMID:34322454. |
renewed interest in the medicinal properties of cannabis has led to increasing research into the practical uses of cannabis derivatives, and it has been found that the endocannabinoid system (particularly cb2 receptor activation) is a possible target for the treatment of inflammatory and the autoimmune diseases related to immune cell activation. |
2021-07-30 |
2023-08-13 |
human |
| Marco Aurélio Mori, Erika Meyer, Francielly F da Silva, Humberto Milani, Francisco Silveira Guimarães, Rúbia Maria Weffort Oliveir. Differential contribution of CB1, CB2, 5-HT1A, and PPAR-γ receptors to cannabidiol effects on ischemia-induced emotional and cognitive impairments. The European journal of neuroscience. vol 53. issue 6. 2021-06-29. PMID:33522084. |
differential contribution of cb1, cb2, 5-ht1a, and ppar-γ receptors to cannabidiol effects on ischemia-induced emotional and cognitive impairments. |
2021-06-29 |
2023-08-13 |
mouse |
| Guo-Hua Bi, Ewa Galaj, Yi He, Zheng-Xiong X. Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents. Addiction biology. vol 25. issue 4. 2021-06-28. PMID:31215752. |
cannabidiol inhibits sucrose self-administration by cb1 and cb2 receptor mechanisms in rodents. |
2021-06-28 |
2023-08-13 |
rat |
| Katarina Čern. Toxicological properties of Δ9-tetrahydrocannabinol and cannabidiol. Arhiv za higijenu rada i toksikologiju. vol 71. issue 1. 2021-05-26. PMID:32597140. |
cannabis sativa l. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors cb1 and cb2. |
2021-05-26 |
2023-08-13 |
Not clear |
| Ewa Galaj, Guo-Hua Bi, Hong-Ju Yang, Zheng-Xiong X. Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT Neuropharmacology. vol 167. 2021-04-23. PMID:31437433. |
cannabidiol attenuates the rewarding effects of cocaine in rats by cb2, 5-ht cocaine abuse continues to be a serious health problem worldwide. |
2021-04-23 |
2023-08-13 |
rat |
| Naielly Rodrigues da Silva, Felipe Villela Gomes, Andreza Buzolin Sonego, Nicole Rodrigues da Silva, Francisco Silveira Guimarãe. Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors. Pharmacological research. vol 156. 2021-04-22. PMID:32151683. |
cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-ht1a, but not cb1 and cb2 receptors. |
2021-04-22 |
2023-08-13 |
mouse |
| Sari Goldstein Ferber, Dvora Namdar, Danielle Hen-Shoval, Gilad Eger, Hinanit Koltai, Gal Shoval, Liat Shbiro, Aron Welle. The "Entourage Effect": Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders. Current neuropharmacology. vol 18. issue 2. 2020-11-03. PMID:31481004. |
cb1 and cb2 receptors primarily serve as the binding sites for endocannabinoids as well as for phytocannabinoids, produced by cannabis inflorescences. |
2020-11-03 |
2023-08-13 |
Not clear |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post, Samy I McFarlan. Marijuana Induced Type I Brugada Pattern: A Case Report. American journal of medical case reports. vol 6. issue 7. 2020-10-01. PMID:30294671. |
marijuana acts on cannabinoid receptors cb1, cb2 and another distinct endothelial receptor. |
2020-10-01 |
2023-08-13 |
Not clear |
| Pramod Theetha Kariyanna, Perry Wengrofsky, Apoorva Jayarangaiah, Syed Haseeb, Louis Salciccioli, Sudhanva Hegde, Jonathan D Marmur, Yasmin Soliman, Sama Al-Bayati, Samy I McFarlan. Marijuana and Cardiac Arrhythmias: A Scoping Study. International journal of clinical research & trials. vol 4. issue 1. 2020-10-01. PMID:31579321. |
delta-9-tetrahydrocannabinol (thc) is the active psychotropic component of marijuana, which acts mainly on g-protein cannabinoid receptors cb1 and cb2. |
2020-10-01 |
2023-08-13 |
Not clear |
| Waqas Jehangir, Michael Stanton, Rafay Khan, Puneet Sahgal, Abdalla Yousi. Did Cannabis Precipitate an STEMI in a Young Woman? Cardiology research. vol 6. issue 3. 2020-09-30. PMID:28197241. |
cannabis is a substance that contains compounds that bind cannabinoid receptors, cb1 and cb2. |
2020-09-30 |
2023-08-13 |
Not clear |
| Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Oleg Yurevich, Jonathan Francois, Denis Yusupov, Angelina Zhyvotovska, Louis Salciccioli, Sudhanva Hegde, Samy I McFarlan. Atrioventricular Nodal Reentrant Tachycardia Triggered by Marijuana Use: A Case Report and Review of the Literature. American journal of medical case reports. vol 7. issue 9. 2020-09-30. PMID:31396556. |
delta-9-tetrahydrocannabinol (thc) is the psychotropic component of marijuana, acting via cb1 and cb2 g-protein coupled cannabinoid receptors. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bruno A Marichal-Cancino, Abimael González-Hernández, Antoinette MaassenVanDenBrink, Eduardo Ramírez-San Juan, Carlos M Villaló. Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats. Journal of vascular research. vol 57. issue 3. 2020-09-14. PMID:32248195. |
bolus of the antagonists nida41020 (cb1), am630 (cb2), capsazepine (trpv1), and/or cannabidiol (gpr55). |
2020-09-14 |
2023-08-13 |
rat |