Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Qinqin Hao, Junrong Yan, Jing Ren, Junli Cheng, Zhiwei Zhu, Pengfei L. [Screening of the lncRNA SNHG3 regulating Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 40. issue 7. 2024-07-24. PMID:39044582. |
[screening of the lncrna snhg3 regulating this study aimed to screen for the long non-coding rna (lncrna) small nucleolar rna host gene 3 (snhg3) capable of regulating the expression of cocaine- and amphetamine-regulated transcriptional peptide (cart) in the bovine hypothalamus and elucidate the underlying mechanism. |
2024-07-24 |
2024-07-26 |
cattle |
Yan Wang, Shuai Ma, Mindie Zhao, Lei Wu, Ruqian Zha. Antibiotic-Induced Gut Microbial Dysbiosis Reduces the Growth of Weaning Rats via FXR-Mediated Hepatic IGF-2 Inhibition. Nutrients. vol 16. issue 11. 2024-06-19. PMID:38892577. |
furthermore, decreased appetite may be attributed to elevated levels of glucagon-like peptide-1 (glp-1) in the serum, along with reduced neuropeptide y (npy) and increased cocaine and amphetamine-regulated transcript (cart) in the hypothalamus at the mrna level. |
2024-06-19 |
2024-06-21 |
rat |
Persephone A Miller, Jesukhogie G Williams-Ikhenoba, Aditi S Sankhe, Brendan H Hoffe, Melissa J Che. Neuroanatomical, electrophysiological, and morphological characterization of melanin-concentrating hormone cells coexpressing cocaine- and amphetamine-regulated transcript. The Journal of comparative neurology. vol 532. issue 2. 2024-02-10. PMID:38335050. |
half of mch cells expressed cart and were most prominent in the medial hypothalamus. |
2024-02-10 |
2024-02-12 |
mouse |
Shupeng Zhang, Yongpei Lu, Yanling Liu, Qin Kang, Qin Yao, Yingzi Li, Shuhuang Chen, Youlian Liu, Jiayi Du, Yixiao Xiong, Wenwen Zhu, Defang Chen, Xin Zhang, Ni Tang, Zhiqiong L. Identification of C1q/TNF-related protein 4 as a novel appetite-regulating peptide that reduces food intake in Siberian sturgeon (Acipenser baerii). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2024-01-08. PMID:38191049. |
the findings demonstrated that abctrp4 treatment for 1 h significantly promoted the mrna levels of anorexigenic peptides (pomc, cart, and leptin) while suppressing the mrna abundances of orexigenic peptides (npy and agrp).in addition, the jak2/stat3 pathway in the hypothalamus was significantly activated after 1 h of abctrp4 treatment. |
2024-01-08 |
2024-01-10 |
Not clear |
Kayvan Khoramipour, Maryam Hossein Rezaei, Elham Madadizadeh, Mahdieh Sadat Hosseini, Zahra Soltani, Janis Schierbauer, Othmar Mose. High Intensity Interval Training can Ameliorate Hypothalamic Appetite Regulation in Male Rats with Type 2 Diabetes: The Role of Leptin. Cellular and molecular neurobiology. 2023-10-12. PMID:37828299. |
anova and tukey post hoc tests were used to compare the results between the groups. the levels of leps and ins, as well as the levels of lep-r, jak-2, stat-3, pomc, and cart in the hypothalamus were found to be higher in the t2d + ex group compared to the t2d group. |
2023-10-12 |
2023-10-15 |
rat |
Kayvan Khoramipour, Maryam Hossein Rezaei, Elham Madadizadeh, Mahdieh Sadat Hosseini, Zahra Soltani, Janis Schierbauer, Othmar Mose. High Intensity Interval Training can Ameliorate Hypothalamic Appetite Regulation in Male Rats with Type 2 Diabetes: The Role of Leptin. Cellular and molecular neurobiology. 2023-10-12. PMID:37828299. |
graphical abstract (leptin signaling in the hypothalamus), leptin (lep), leptin receptor (lep-r), janus kinase 2 (jak2), signal transducer and activator of transcription 3 (stat3), expressing neuropeptide y (npy), agouti-related protein (agrp), anorexigenic neurons (expressing pro-opiomelanocortin cocaine (pomc), amphetamine-related transcript (cart), suppressor of cytokine signaling (socs3), forkhead box protein o1 (foxo1). |
2023-10-12 |
2023-10-15 |
rat |
Di Peng, Linwei Yang, Xu-Fang Liang, Farui Cha. Dietary zinc levels affect growth, appetite, and lipid metabolism of Chinese perch (Siniperca chuatsi). Fish physiology and biochemistry. 2023-09-17. PMID:37718352. |
the qrt-pcr results showed that the expression of center appetite regulation factors in the hypothalamus was significantly regulated, and 149 mg/kg significantly increased mrna expression of npy (neuropeptide y) and decreased pomc (anorexigenic proopiomelanocortin) and cart (cocaine- and amphetamine-regulated transcript) gene expression. |
2023-09-17 |
2023-10-07 |
Not clear |
Shobha Bhargava, Ketaki Shetye, Swapnil Shewale, Nitin Sawant, Sneha Sagarkar, Nishikant Subheda. Mate calling alters expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain of male frog Microhyla nilphamariensis. Neuropeptides. vol 102. 2023-09-10. PMID:37690194. |
cart immunoreactivity was far more in the preoptic area (poa), anteroventral tegmentum (av), ventral hypothalamus (vhy), pineal (p) and pituitary gland of croaking frog compared to non-croaking animals. |
2023-09-10 |
2023-10-07 |
Not clear |
Y Y Zhao, C X Li, X Y Wang, Z J Wang, J C Wang, W R Zhen, S C Huang, T S Li, H Y Fan, Y B Ma, C Zhan. Effects of Glycyrrhiza polysaccharide on growth performance, appetite, and hypothalamic inflammation in broilers. Journal of animal science. 2023-01-18. PMID:36652259. |
from day 1 to day 21, the addition of gcp to the diet significantly improved the adfi and the adg of broilers, and the mrna levels of npy and agrp were significantly increased while pomc and cart were decreased in the hypothalamus of broilers; gcp also significantly decreased the mrna levels of il-1β, il-6, tnf-α, tlr-4, myd88 and nf-κb, and increased the il-4 and il-10 in the hypothalamus from day 1 to day 42. |
2023-01-18 |
2023-08-14 |
Not clear |
Sevag Hamamah, Mihai Covas. Gut Microbiota Restores Central Neuropeptide Deficits in Germ-Free Mice. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233056. |
specifically, we injected and measured serum leptin in both gf and conv-r mice and measured expression of orexigenic and anorexigenic peptides npy, agrp, pomc, and cart in the hypothalamus and hindbrain to examine whether the gm has an impact on central nervous system regulation of energy homeostasis. |
2022-10-14 |
2023-08-14 |
mouse |
Kavita N Hadawale, Swapnil Shewale, Ketaki C Shetye, Sneha Sagarkar, Amul Sakharkar, Shobha Y Bhargav. Reproductive phase related variations in the expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain and pituitary gland of adult male Microhyla ornata. Neuroscience letters. 2022-07-10. PMID:35810962. |
similarly, highest mrna levels of cart were also observed in the breeding season in the middle region of brain that includes hypothalamus and pituitary gland. |
2022-07-10 |
2023-08-14 |
Not clear |
Rafael Estevan Sabioni, Evandro Kleber Lorenz, José Eurico Possebon Cyrino, Helene Volkof. Feed intake and gene expression of appetite-regulating hormones in Salminus brasiliensis fed diets containing soy protein concentrate. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2022-04-03. PMID:35367384. |
this study aimed at evaluating feed intake and gene expression of appetite- regulating hormones [orexin, cocaine and amphetamine regulated transcript (cart), leptin, cholecystokinin (cck) and peptide yy (pyy)] in the intestine, pyloric caeca and hypothalamus of juvenile dourado fed diets containing graded levels of spc and fm as dietary protein sources for a period of three weeks. |
2022-04-03 |
2023-08-13 |
Not clear |
Taisy Cinthia Ferro Cavalcante, Renata Cristinny de Farias Campina, Julliet Araújo de Souza, Amanda Alves Marcelino da Silva, Sandra Lopes de Souz. Hypothalamic peptide and nutrient sensors gene expression in the hypothalamus of neonatal rat. Brain research bulletin. vol 164. 2021-10-29. PMID:32858126. |
gene expression of hypothalamic peptides, neuropeptide y(npy), agouti-related peptide(agrp), proopiomelanocortin(pomc), cocaine-and amphetamine-regulated transcript(cart), and energy sensors mechanistic target of rapamycin(mtor) and amp-activated protein kinase(ampk) in the hypothalamus was seen. |
2021-10-29 |
2023-08-13 |
rat |
Xiao-Yan Liu, Jian-Hua Shi, Wen-Hua DU, Yan-Ping Fan, Xiao-Lei Hu, Chen-Chen Zhang, Huan-Bai Xu, Yan-Jun Miao, Hai-Yan Zhou, Ping Xiang, Feng-Ling Che. Glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats. Experimental and therapeutic medicine. vol 2. issue 5. 2021-10-21. PMID:22977608. |
the expression levels of npy, agrp and cart mrna in the hypothalamus were measured by real-time quantitative pcr. |
2021-10-21 |
2023-08-12 |
rat |
Xiao-Yan Liu, Jian-Hua Shi, Wen-Hua DU, Yan-Ping Fan, Xiao-Lei Hu, Chen-Chen Zhang, Huan-Bai Xu, Yan-Jun Miao, Hai-Yan Zhou, Ping Xiang, Feng-Ling Che. Glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats. Experimental and therapeutic medicine. vol 2. issue 5. 2021-10-21. PMID:22977608. |
gc treatment decreased appetite and body weight, induced apparent glucolipid metabolic disturbances and hyperinsulinemia, while down-regulated mrna expression levels of the orexigenic neuropeptides, npy and agrp, and anorexigenic neuropeptide, cart, in the hypothalamus in the rats. |
2021-10-21 |
2023-08-12 |
rat |
Zhi Yi Ong, Gavan P McNall. CART in energy balance and drug addiction: Current insights and mechanisms. Brain research. vol 1740. 2021-09-01. PMID:32335093. |
cocaine amphetamine related transcript (cart) is a neuropeptide first isolated and sequenced from ovine hypothalamus and later shown to have functions related to drug taking, drug seeking, and energy balance. |
2021-09-01 |
2023-08-13 |
Not clear |
Anna Idelevich, Kazusa Sato, Byron Avihai, Kenichi Nagano, Antonin Galien, Glenn Rowe, Francesca Gori, Roland Baro. Both NPY-Expressing and CART-Expressing Neurons Increase Energy Expenditure and Trabecular Bone Mass in Response to AP1 Antagonism, But Have Opposite Effects on Bone Resorption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 35. issue 6. 2021-07-28. PMID:31995643. |
within the ventral hypothalamus (vht), the orexigenic neurons co-express agouti-related peptide (agrp) and neuropeptide y (npy) and the anorexigenic neurons co-express, α-melanocyte stimulating hormone derived from proopiomelanocortin (pomc), and cocaine and amphetamine-regulated transcript (cart). |
2021-07-28 |
2023-08-13 |
mouse |
Swapnil A Shewale, Shantaj M Deshbhratar, Ameeta Ravikumar, Shobha Y Bhargav. Cocaine and amphetamine regulated transcript peptide (CART) in the tadpole brain: Response to different energy states. Neuropeptides. vol 88. 2021-07-12. PMID:33932859. |
glucose administration increased the cart immunoreactivity in the entopeduncular neurons (en), preoptic area (poa), ventral hypothalamus (vhy) and the edinger westphal nucleus (ew) while cart positive cells decrease in response to fasting and glucoprivation. |
2021-07-12 |
2023-08-13 |
Not clear |
Xiaoping Jing, Yamin Guo, Allan Degen, Wenji Wang, Jingpeng Kang, Luming Ding, Zhanhuan Shang, Ruijun Long, Jianwei Zho. Hypothalamic regulation of energy homoeostasis when consuming diets of different energy concentrations: comparison between Tibetan and Small-tailed Han sheep. The British journal of nutrition. 2021-06-30. PMID:34085612. |
the arcuate nucleus of the hypothalamus in tibetan sheep had greater protein expressions of neuropeptide y (npy) and agouti-related peptide (agrp) when in negative energy balance, but lesser protein expressions of proopiomelanocortin (pomc) and cocaine and amphetamine-regulated transcript (cart) when in positive energy balance than small-tailed han sheep. |
2021-06-30 |
2023-08-13 |
Not clear |
Caitlin S Mitchell, Denovan P Beg. The regulation of food intake by insulin in the central nervous system. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33656205. |
within the hypothalamus, the arcuate nucleus (arc) contains subpopulations of neurones that produce orexinergic neuropeptides agouti-related peptide (agrp)/neuropeptide y (npy) and anorexigenic neuropeptides, pro-opiomelanocortin (pomc)/cocaine- and amphetamine-regulated transcript (cart). |
2021-06-15 |
2023-08-13 |
Not clear |