| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Rydzewska, A Gabryelewic. [Diagnostic usefulness and prognostic value of inhibitory capacity and other biochemical parameters of plasma in acute pancreatitis in humans]. Polskie Archiwum Medycyny Wewnetrznej. vol 84. issue 2. 1991-03-05. PMID:1703653. |
no significant differences were noted in the concentration of alpha 1 protease inhibitor and c3 and c4 complement components, in the studied groups. |
1991-03-05 |
2023-08-11 |
human |
| C Y Y. The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene. Journal of immunology (Baltimore, Md. : 1950). vol 146. issue 3. 1991-02-25. PMID:1988494. |
comparison of human c4 with published data for mouse c4, human c3 and rat alpha 2 macroglobulin genes revealed that these evolutionary-related genes share very similar exon-intron structures. |
1991-02-25 |
2023-08-11 |
mouse |
| P O Nylander, L Beckman, G Holmgren, L Stee. Association of C3 and C4A complement types with familial amyloidotic polyneuropathy. Human heredity. vol 40. issue 5. 1991-02-08. PMID:2265853. |
we have studied a number of serum protein markers (alpha 1-antitrypsin, properdin factor b, c3, c4a, c4b, haptoglobin, transferrin and group-specific component) in fap patients and healthy controls in an attempt to identify additional pathogenic factors which may influence the risk for developing fap in male and female patients as well as the age of onset of the disease. |
1991-02-08 |
2023-08-11 |
Not clear |
| F Noël, M Fagoo, T Godfrain. A comparison of the affinities of rat (Na+ + K+)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration. Biochemical pharmacology. vol 40. issue 12. 1991-01-31. PMID:2175607. |
it was observed that: (i) ouabain and digoxin had higher affinity (p less than 0.01) for alpha 3 isozyme (kd of 0.071 +/- 0.004 and 0.066 +/- 0.001 microm, respectively) than for alpha 1 isozyme (kd of 15.9 +/- 0.8 and 1.78 +/- 0.46 microm, respectively) and alpha 2 isozyme (kd of 0.26 +/- 0.04 and 0.15 +/- 0.06 microm, respectively); (ii) saturation of the c20-c22 bond on the c17 beta lactone ring present in ouabain and digoxin markedly decreased the drug affinity for all isozymes (p less than 0.01); and (iii) suppression of the c3 beta osidic chain decreased the affinity of ouabain and digoxin to a higher extent for alpha 2 and alpha 3 than for alpha 1 (p less than 0.01). |
1991-01-31 |
2023-08-11 |
rat |
| S L Reed, I Gigl. Lysis of complement-sensitive Entamoeba histolytica by activated terminal complement components. Initiation of complement activation by an extracellular neutral cysteine proteinase. The Journal of clinical investigation. vol 86. issue 6. 1991-01-22. PMID:2254446. |
activation of complement by entamoeba histolytica may be initiated by the extracellular 56-kd neutral cysteine proteinase which cleaves the alpha chain of c3. |
1991-01-22 |
2023-08-11 |
chicken |
| S L Reed, I Gigl. Lysis of complement-sensitive Entamoeba histolytica by activated terminal complement components. Initiation of complement activation by an extracellular neutral cysteine proteinase. The Journal of clinical investigation. vol 86. issue 6. 1991-01-22. PMID:2254446. |
when 125i-c3 was incubated with trophozoites in serum, c3 in the fluid phase was cleaved to c3b or c3bi, but the alpha chain of the c3 molecules on the cell surface appeared intact. |
1991-01-22 |
2023-08-11 |
chicken |
| N Basset-Séguin, S W Caughman, K B Yance. A-431 cells and human keratinocytes synthesize and secrete the third component of complement. The Journal of investigative dermatology. vol 95. issue 6. 1991-01-17. PMID:2250103. |
pulse-chase studies in a-431 cells demonstrate that epithelial cell-derived c3 is produced as a 195-kd precursor molecule, pro-c3, which is processed intracellularly by limited proteolysis into 120- and 75-kd c3 alpha and beta chains. |
1991-01-17 |
2023-08-11 |
human |
| N Basset-Séguin, S W Caughman, K B Yance. A-431 cells and human keratinocytes synthesize and secrete the third component of complement. The Journal of investigative dermatology. vol 95. issue 6. 1991-01-17. PMID:2250103. |
treatment of biosynthetically labeled a-431 cell culture supernatants with normal human serum and zymosan produces c3 alpha chain cleavage and specific c3 fragments that are not present in control culture supernatants treated with heat-inactivated human serum and zymosan. |
1991-01-17 |
2023-08-11 |
human |
| B Nilsson, K N Ekdahl, M Svarvare, A Bjelle, U R Nilsso. Purification and characterization of IgG immunoconglutinins from patients with systemic lupus erythematosus: implications for a regulatory function. Clinical and experimental immunology. vol 82. issue 2. 1990-12-31. PMID:2146995. |
furthermore, western blot analysis revealed no immunoconglutinin-binding to reduced c3 peptides and no binding was shown to soluble c3 alpha and beta chain by elisa. |
1990-12-31 |
2023-08-11 |
human |
| B Nilsson, K N Ekdahl, M Svarvare, A Bjelle, U R Nilsso. Purification and characterization of IgG immunoconglutinins from patients with systemic lupus erythematosus: implications for a regulatory function. Clinical and experimental immunology. vol 82. issue 2. 1990-12-31. PMID:2146995. |
the two former immunoconglutinins also inhibited all three factor i cleavages in c3 alpha chain but the latter inhibited only the third cleavage. |
1990-12-31 |
2023-08-11 |
human |
| K S Ulicny, L F Hiratzka, R B Williams, G L Grunkemeier, J B Flege, C B Wright, G M Callard, D L Mitts, E J Dun. Sternotomy infection: poor prediction by acute phase response and delayed hypersensitivity. The Annals of thoracic surgery. vol 50. issue 6. 1990-12-26. PMID:1700683. |
there was no significant correlation between preoperative nutritional protein concentrations (retinol-binding protein, prealbumin, and transferrin) and acute phase protein levels (c-reactive protein, alpha 1-acid glycoprotein, and complements b and c3), nor a statistically significant relationship between nutritional state or acute phase protein response and the development of sternal infection. |
1990-12-26 |
2023-08-11 |
Not clear |
| K S Ulicny, L F Hiratzka, R B Williams, G L Grunkemeier, J B Flege, C B Wright, G M Callard, D L Mitts, E J Dun. Sternotomy infection: poor prediction by acute phase response and delayed hypersensitivity. The Annals of thoracic surgery. vol 50. issue 6. 1990-12-26. PMID:1700683. |
although statistically insignificant, possibly due to the small number of patients in whom sternal infection developed in this study (type ii error), a larger study might find preoperative complement c3 and post-operative alpha 1-acid glycoprotein levels to be predictive of patients at risk for the development of sternal wound infection. |
1990-12-26 |
2023-08-11 |
Not clear |
| C T Wong, N Sah. Changes in serum proteins (albumin, immunoglobulins and acute phase proteins) in pulmonary tuberculosis during therapy. Tubercle. vol 71. issue 3. 1990-12-18. PMID:1700523. |
serum levels of three immunoglobulins (igg, iga & igm), albumin and six acute phase proteins (alpha 1-antitrypsin, haptoglobin, transferrin, alpha 2-macroglobulin, complements c3 & c4) were measured by immunoelectrophoresis in 57 patients with pulmonary tuberculosis when they were first diagnosed, and followed at 1 month, 2 month and 4 month intervals during anti-tuberculosis treatment. |
1990-12-18 |
2023-08-11 |
Not clear |
| G Lengyel, B Joachim, G Acs, J Fehé. [The role of interleukin-1 beta in the regulation of liver-specific gene expression in human hepatoblastoma cells]. Orvosi hetilap. vol 131. issue 42. 1990-12-12. PMID:2172889. |
they found that treating human hepatoma (hep g2) cells with interleukin-1 (il-1) leads to the induction of alpha-1-acidglycoprotein (agp) and complement 3 (c3) mrna synthesis, and to a concomitant downregulation of albumin (alb), alpha-fetoprotein (afp) and alpha-2-macroglobulin (alpha 2m) mrna synthesis. |
1990-12-12 |
2023-08-11 |
human |
| R W Baro. Cleavage of purified bovine complement component C3 in larval Hypoderma lineatum (Diptera: Oestridae) hypodermins. Journal of medical entomology. vol 27. issue 5. 1990-12-05. PMID:2231625. |
crude extracts (raw insect homogenate) and purified hypodermin a and b were effective in degrading the alpha chain of c3 at a concentration of 1 microgram/ml. |
1990-12-05 |
2023-08-11 |
cattle |
| M Botto, K Y Fong, A K So, A Rudge, M J Walpor. Molecular basis of hereditary C3 deficiency. The Journal of clinical investigation. vol 86. issue 4. 1990-11-21. PMID:2212005. |
30 exons have been characterized, spanning the entire beta chain of c3 and the alpha chain as far as the c3d region. |
1990-11-21 |
2023-08-11 |
Not clear |
| K R Dadiani, N E Voĭto, V A Tutel'ia. [The immunological reactivity indices (the humoral component) in persons in contact with mycotoxin-contaminated food products]. Voprosy pitaniia. issue 3. 1990-10-18. PMID:2399678. |
blood serum levels of immunoglobulins (igg, iga, igm, igd, ige), concentration of complement components (c1-inhibitor, c3, c4, c5, c9) as well as the content of some protein fractions (transferrin, ceruloplasmin, haptoglobin, orosomucoid, alpha 1-antitrypsin, alpha 2-macroglobulin, albumin and prealbumin) in the plasma were assayed in subjects exposed (due to their occupational necessity) to food raw materials (wheat, corn, barley, combined fodder) contaminated with mycotoxins. |
1990-10-18 |
2023-08-11 |
human |
| Iu V Krizhevskaia, L M Vavilova, M Iu Kuz'micheva, O A Markova, N N Tibilova, O N Ermol'chu. [Study of the complement system and the inhibitors of plasma proteolytic enzymes in the erythrocytes during blood preservation]. Gematologiia i transfuziologiia. vol 35. issue 5. 1990-10-09. PMID:1697549. |
a decrease, detected in the level of c1, c3 and alpha 2-macroglobulin, was more pronounced in the erythroconcentrate than in the red blood cell pack. |
1990-10-09 |
2023-08-11 |
Not clear |
| L Sottrup-Jensen, W Borth, M Hall, J P Quigley, P B Armstron. Sequence similarity between alpha 2-macroglobulin from the horseshoe crab, Limulus polyphemus, and proteins of the alpha 2-macroglobulin family from mammals. Comparative biochemistry and physiology. B, Comparative biochemistry. vol 96. issue 3. 1990-10-04. PMID:1697231. |
purified alpha 2-macroglobulin (alpha 2m) from the american horseshoe crab, limulus polyphemus was cleaved with trypsin and 20 of the tryptic peptides were sequenced and compared with the sequences of human alpha 2m, rat alpha 1m, alpha 2m, and alpha 1-inhibitor 3, and human complement proteins c3 and c4. |
1990-10-04 |
2023-08-11 |
human |
| Y Misumi, K Ohkubo, M Sohda, N Takami, K Oda, Y Ikehar. Intracellular processing of complement pro-C3 and proalbumin is inhibited by rat alpha 1-protease inhibitor variant (Met352----Arg) in transfected cells. Biochemical and biophysical research communications. vol 171. issue 1. 1990-10-04. PMID:2393391. |
complement c3, when its cdna was transfected into cos-1 cells, was synthesized as a precursor, pro-c3, which was intracellularly processed into the alpha and beta subunits, although not completely. |
1990-10-04 |
2023-08-11 |
rat |