| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A A Galoyan, Gurvitis BYa, L A Shuvalova, M T Davis, J E Shively, T D Le. A hypothalamic activator of calmodulin-dependent enzymes is thymosin beta 4 (1-39). Neurochemical research. vol 17. issue 8. 1992-09-03. PMID:1641059. |
the potency of the stimulators in activating the enzyme was: c3 greater than beta 4 greater than (cam+ca2+) greater than alpha 1. |
1992-09-03 |
2023-08-11 |
rabbit |
| N Julen, C Davrinche, D Ozanne, J P Lebreton, M Fontaine, J Ripoche, M Davea. Differential modulation of complement factor H and C3 expression by TNF-alpha in the rat. In vitro and in vivo studies. Molecular immunology. vol 29. issue 7-8. 1992-08-26. PMID:1386144. |
recombinant human interleukin-1 alpha (rhil-1 alpha) did not alter the expression of factor h, whereas it increased c3 expression, and recombinant human interleukin-6 (rhil-6) stimulated expression of both proteins. |
1992-08-26 |
2023-08-11 |
human |
| M Botto, K Y Fong, A K So, R Barlow, R Routier, B J Morley, M J Walpor. Homozygous hereditary C3 deficiency due to a partial gene deletion. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 11. 1992-06-26. PMID:1350678. |
restriction enzyme analysis showed a gene deletion of 800 base pairs (bp) mapping to the alpha chain of c3. |
1992-06-26 |
2023-08-11 |
Not clear |
| L Isaac, D E Isenma. Structural requirements for thioester bond formation in human complement component C3. Reassessment of the role of thioester bond integrity on the conformation of C3. The Journal of biological chemistry. vol 267. issue 14. 1992-06-09. PMID:1577777. |
a unique thioester bond, formed between the side chains of neighboring c and q residues, is present in complement components c3 and c4 and the protease inhibitor alpha 2-macroglobulin. |
1992-06-09 |
2023-08-11 |
human |
| M Nonaka, M Takahash. Complete complementary DNA sequence of the third component of complement of lamprey. Implication for the evolution of thioester containing proteins. Journal of immunology (Baltimore, Md. : 1950). vol 148. issue 10. 1992-06-09. PMID:1578150. |
lamprey liver mrna sequences were amplified by reverse transcriptase-polymerase chain reaction using primers synthesized according to the amino acid sequences at the thioester region common to the mammalian c3, c4, and alpha 2-macroglobulin (alpha 2m). |
1992-06-09 |
2023-08-11 |
mouse |
| M Nonaka, M Takahash. Complete complementary DNA sequence of the third component of complement of lamprey. Implication for the evolution of thioester containing proteins. Journal of immunology (Baltimore, Md. : 1950). vol 148. issue 10. 1992-06-09. PMID:1578150. |
two different cdna species were identified that showed a close similarity to the mammalian c3 or alpha 2m sequences, respectively. |
1992-06-09 |
2023-08-11 |
mouse |
| M Nonaka, M Takahash. Complete complementary DNA sequence of the third component of complement of lamprey. Implication for the evolution of thioester containing proteins. Journal of immunology (Baltimore, Md. : 1950). vol 148. issue 10. 1992-06-09. PMID:1578150. |
the deduced amino acid sequence of the putative lamprey pro-c3 contained 1660 amino acids and showed 31%, 22%, 23%, and 16% amino acid sequence identity with mouse c3, c4, c5, and human alpha 2m, respectively. |
1992-06-09 |
2023-08-11 |
mouse |
| M K Pangbur. Spontaneous reformation of the intramolecular thioester in complement protein C3 and low temperature capture of a conformational intermediate capable of reformation. The Journal of biological chemistry. vol 267. issue 12. 1992-05-28. PMID:1569104. |
three human plasma proteins contain intramolecular thioester bonds: complement components c3 and c4 and alpha 2-macroglobulin. |
1992-05-28 |
2023-08-11 |
human |
| U Schöffel, F Bonnaire, B U van Specht, E H Kune. Monitoring the response to injury. Injury. vol 22. issue 5. 1992-05-14. PMID:1806499. |
in severely injured patients with multiple trauma three out of 14 parameters measured at the time of admission proved to be indicators of subsequent septic complications with a high degree of accuracy: fibrinopeptide a (fpa--the first split product of fibrinogen), the c3 split product c3a, and the elastase-alpha 1 proteinase inhibitor-complex (e alpha 1 pi). |
1992-05-14 |
2023-08-11 |
Not clear |
| H Matsuo, M Tsujihata, A Satoh, G Takeo, T Yoshimura, S Nagatak. Myasthenogenicity of a human acetylcholine receptor alpha-subunit peptide: morphology and immunology. Muscle & nerve. vol 15. issue 3. 1992-05-07. PMID:1372965. |
each of 10 rats inoculated with a synthetic peptide comprising residues 125-147 (without a disulfide bond) of human acetylcholine receptor (achr) alpha-subunit (h alpha) had deposits of igg and c3 (immune complexes) and showed morphological changes in the fine structure at the motor end-plates 5 weeks after a single immunization. |
1992-05-07 |
2023-08-11 |
human |
| E Yefenof, I Algarra, O F Ramos, E Klei. Activation and fixation of C3 by human B cell lines is enhanced by interferon-gamma and tumor necrosis factor alpha. Complement and inflammation. vol 8. issue 5-6. 1992-04-24. PMID:1666351. |
activation and fixation of c3 by human b cell lines is enhanced by interferon-gamma and tumor necrosis factor alpha. |
1992-04-24 |
2023-08-11 |
human |
| E Yefenof, I Algarra, O F Ramos, E Klei. Activation and fixation of C3 by human B cell lines is enhanced by interferon-gamma and tumor necrosis factor alpha. Complement and inflammation. vol 8. issue 5-6. 1992-04-24. PMID:1666351. |
all cell lines activated c3 with higher efficiency when treated with interferon gamma or tumor necrosis factor alpha. |
1992-04-24 |
2023-08-11 |
human |
| U Wolf, D Bauer, W H Trau. Collagenase of Clostridium perfringens type A: degradation of human complement component C1q. Zentralblatt fur Bakteriologie : international journal of medical microbiology. vol 276. issue 1. 1992-04-02. PMID:1665065. |
the following purified human serum proteins were refractory: c components c3, c4, c5, c6, c7, c8, and c9; immunoglobulin (ig)a (from colostrum), igg, and igm; alpha 2-macroglobulin, haptoglobin, and c-reactive protein. |
1992-04-02 |
2023-08-11 |
human |
| U Wolf, D Bauer, W H Trau. Metalloproteases of Serratia liquefaciens: degradation of purified human serum proteins. Zentralblatt fur Bakteriologie : international journal of medical microbiology. vol 276. issue 1. 1992-04-02. PMID:1724153. |
as demonstrated with sds-page electrophoresis, the two metalloproteases attacked the following purified human serum proteins: complement components c3, c4, c5, c6, c7, c8, and c9, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, fibronectin, type iii fibrinogen, immunoglobulin g (heavy chains), and igm (heavy chains). |
1992-04-02 |
2023-08-11 |
human |
| T Onbe, H Makino, T Haramoto, J Wada, T Ogura, I Kumagai, K Murakami, M Fukushima, Z Ot. [Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect]. Nihon Jinzo Gakkai shi. vol 33. issue 8. 1992-02-27. PMID:1770635. |
in order to reveal the mechanism of the effect laboratory data such as granulocyte elastase, ch50, c3, c4, fibrinogen, platelate factor 4, beta-thromboglobulin, thromboxane b2 and prostaglandin f1 alpha were evaluated before and after the treatment. |
1992-02-27 |
2023-08-11 |
Not clear |
| H G Rus, L M Kim, F I Niculescu, M L Shi. Induction of C3 expression in astrocytes is regulated by cytokines and Newcastle disease virus. Journal of immunology (Baltimore, Md. : 1950). vol 148. issue 3. 1992-02-19. PMID:1530957. |
tnf, il-1 beta, and il-8 also increased the levels of c3 mrna and protein whereas il-1 alpha and il-6 had no effect, although all of these cytokines are inducible by lps. |
1992-02-19 |
2023-08-11 |
rat |
| M Miyazaki, L Bai, H Taga, H Hirai, J Sato, M Namb. Expression of liver-specific functions and secretion of a hepatocyte growth factor by a newly established rat hepatoma cell line growing in a chemically-defined serum-free medium. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 191. issue 5. 1992-02-06. PMID:1836893. |
also, the cells secreted alpha-fetoprotein, albumin, transferrin, alpha 1-acid glycoprotein, c-reactive protein, fibrinogen, complement component c3, and other five-serum proteins. |
1992-02-06 |
2023-08-11 |
rat |
| H Hayakawa, A Sato, K Chida, M Iwat. [The significance of the heparin precipitable fraction in lung diseases]. Nihon Kyobu Shikkan Gakkai zasshi. vol 29. issue 8. 1992-01-30. PMID:1721660. |
the data revealed that there were correlations between hpf and esr, crp, alpha 1-globulin, alpha 2-globulin, complement (c3) or fibrinogen. |
1992-01-30 |
2023-08-11 |
human |
| R E Spitzer, A E Stitzel, G C Tsoko. Autoantibody to the alternative pathway C3/C5 convertase and its anti-idiotypic response. A study in affinity. Journal of immunology (Baltimore, Md. : 1950). vol 148. issue 1. 1992-01-27. PMID:1727863. |
in an effort to understand the development and control of autoantibody production, we studied the affinity of autoantibody to the alternative pathway c3/c5 convertase (c3 nephritic factor (c3nef)) and its autoanti-idiotypic antibodies, ab2 alpha and ab2 beta. |
1992-01-27 |
2023-08-11 |
human |
| M Elkashab, P Lal. PGE2 receptors on murine splenic lymphocytes: effects of tumor bearing. Immunology letters. vol 30. issue 1. 1992-01-09. PMID:1660031. |
pge2 receptors were examined on both unfractionated and monocyte-macrophage-depleted splenocytes of normal or tumor-bearing c3h/hej mice (at 25 days following s.c. transplantation of 10(6) c3 mammary adenocarcinoma cells) using a [3h]pge2 binding assay in the presence of increasing (up to 10(4)-fold) concentrations of unlabeled pge2 (or pga or pgf2 alpha as specificity controls) followed by a scatchard analysis. |
1992-01-09 |
2023-08-11 |
mouse |