| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shane A Perrine, Jonathon S Miller, Ellen M Unterwal. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18717814. |
amygdala, nucleus accumbens, caudate putamen, and hippocampus tissues were dissected 30 min following the last injection and analyzed for phosphorylated and total akt and gsk3(alpha and beta) protein levels using western blot analysis. |
2008-12-24 |
2023-08-12 |
rat |
| Amita Kapoor, Jason Leen, Stephen G Matthew. Molecular regulation of the hypothalamic-pituitary-adrenal axis in adult male guinea pigs after prenatal stress at different stages of gestation. The Journal of physiology. vol 586. issue 17. 2008-12-18. PMID:18635650. |
corticosteroid receptors in the hippocampus, hypothalamus and pituitary were measured, as well as corticotropin-releasing hormone (crh), pro-opiomelanocortin (pomc) and adrenal enzymes in the paraventricular nucleus, pituitary and adrenal cortex, respectively, by in situ hybridization and western blot. |
2008-12-18 |
2023-08-12 |
human |
| Stacy L Sell, Rebecca M Craft, Patricia K Seitz, Sonja J Stutz, Kathryn A Cunningham, Mary L Thoma. Estradiol-sertraline synergy in ovariectomized rats. Psychoneuroendocrinology. vol 33. issue 8. 2008-12-09. PMID:18650020. |
immediately after the fst, midbrain, hippocampus and prefrontal cortex tissue was removed and frozen for analysis of gene expression via quantitative real-time pcr (midbrain tissue) and protein expression via western blot (prefrontal cortex and hippocampal tissue). |
2008-12-09 |
2023-08-12 |
rat |
| Katarina Stark, Zhong-Liu Wu, Cheryl J Bartleson, F Peter Guengeric. mRNA distribution and heterologous expression of orphan cytochrome P450 20A1. Drug metabolism and disposition: the biological fate of chemicals. vol 36. issue 9. 2008-11-07. PMID:18541694. |
mrna expression was detected in human liver, and extrahepatic expression was noted in several human brain regions, including substantia nigra, hippocampus, and amygdala, using conventional polymerase chain reaction and rna dot blot analysis. |
2008-11-07 |
2023-08-12 |
human |
| Saravana R K Murthy, Georgeta Teodorescu, Ingrid M Nijholt, Amalia M Dolga, Stephan Grissmer, Joachim Spiess, Thomas Blan. Identification and characterization of a novel, shorter isoform of the small conductance Ca2+ -activated K+ channel SK2. Journal of neurochemistry. vol 106. issue 6. 2008-11-07. PMID:18624921. |
western blot analysis of mouse hippocampal tissue revealed a 47 kda protein product as predicted for sk2-sh along with a 64 kda band representing the standard sk2 isoform. |
2008-11-07 |
2023-08-12 |
mouse |
| A Toledano, M I Alvarez, I Caballero, P Carmona, E De Migue. Immunohistochemical increase in cyclooxygenase-2 without apoptosis in different brain areas of subchronic nicotine- and D-amphetamine-treated rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 8. 2008-10-24. PMID:18351285. |
to clarify whether nicotine-induced upregulation of cox-2 occurs, and to analyse its significance, a comparative immunohistochemical and western blot study was performed on the frontoparietal cortex, hippocampus and cerebellar cortex of rats treated (14 days) with nicotine, d(+)amphetamine (0.35 and 1.16 mg free base/kg/day, respectively), or both drugs simultaneously. |
2008-10-24 |
2023-08-12 |
rat |
| A Toledano, M I Alvarez, I Caballero, P Carmona, E De Migue. Immunohistochemical increase in cyclooxygenase-2 without apoptosis in different brain areas of subchronic nicotine- and D-amphetamine-treated rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 8. 2008-10-24. PMID:18351285. |
western blot analysis revealed a 50-80% increase in cox-2 in the brain cortex and hippocampus of nicotine-treated rats, and similar increases (150-200%) in the cortex of the d(+)amphetamine- and nicotine + d(+)amphetamine-treated rats. |
2008-10-24 |
2023-08-12 |
rat |
| Charles E Wood, Maureen Keller-Woo. Ontogeny of androgen receptor expression in the ovine fetal central nervous system and pituitary. Neuroscience letters. vol 439. issue 2. 2008-10-14. PMID:18514409. |
in hippocampus and brainstem ar mrna was constant throughout the latter half of gestation, and ar protein was below the sensitivity of our western blot assay. |
2008-10-14 |
2023-08-12 |
Not clear |
| Jungsook Cho, Donna L Gruo. The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells. Journal of neuroimmunology. vol 199. issue 1-2. 2008-10-14. PMID:18584881. |
in the current study, western blot analysis showed that in rat hippocampal neuronal/glial cultures the signal transduction pathway activated by ccl2, a chemokine expressed in the normal brain and at elevated levels during neuroinflammation, involves a g-protein coupled receptor, p38 mapk as well as its immediate upstream kinase mkk3/6, and the downstream transcription factor creb. |
2008-10-14 |
2023-08-12 |
rat |
| Lin Xiao, Yizhang Che. Culture condition and embryonic stage dependent silence of glucocorticoid receptor expression in hippocampal neurons. The Journal of steroid biochemistry and molecular biology. vol 111. issue 1-2. 2008-09-30. PMID:18625317. |
in this study, using western blot, immunofluorescence staining and real-time rt-pcr, we found that while this silence occurred in hippocampal neurons isolated from e16 and e18 rats, it did not happen in those from e20 and neonatal (p0) rats. |
2008-09-30 |
2023-08-12 |
rat |
| Kazue Kikuchi-Utsumi, Toshio Nakak. Chronic treatment with a selective ligand for the sigma-1 receptor chaperone, SA4503, up-regulates BDNF protein levels in the rat hippocampus. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18547721. |
bdnf protein levels were estimated by western blot analysis in the striatum, midbrain, frontal cortex, hippocampus and thalamus. |
2008-09-26 |
2023-08-12 |
rat |
| Tao Wen, Yu-Chun Liu, Hui-Wen Yang, Hai-Yan Liu, Xiao-Dong Liu, Guang-Ji Wang, Lin Xi. Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain. Journal of the neurological sciences. vol 270. issue 1-2. 2008-09-24. PMID:18440557. |
western blot result suggested that the protein level of p-gp in cortex and hippocampus of rats exposed to drugs was significantly higher than that of control rats. |
2008-09-24 |
2023-08-12 |
rat |
| Ichiro Nozaki, Takuo Watanabe, Makoto Kawaguchi, Hiroyasu Akatsu, Koichi Tsuneyama, Yasuhiko Yamamoto, Kazuyo Ohe, Hideto Yonekura, Masahito Yamada, Hiroshi Yamamot. Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains. Archives of histology and cytology. vol 70. issue 5. 2008-09-19. PMID:18431028. |
in this study, the expression of esrage in the hippocampal tissues from ad brains compared with control (non-ad) was examined by immunohistochemistry and western blot analysis. |
2008-09-19 |
2023-08-12 |
Not clear |
| Thomas F Tropea, Barry E Kosofsky, Anjali M Rajadhyaksh. Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18554320. |
to better understand the mechanism of cocaine-conditioned place preference we have used western blot analysis to examine changes in phosphorylation of camp-response element binding protein (creb), dopamine- and cyclic amp-regulated phosphoprotein 32 (darpp-32), extracellular signal-regulated kinase (erk) and glur1, key molecular substrates altered by cocaine, in the nucleus accumbens (nac) and dorsal hippocampus (dhc) of c57bl/6 mice. |
2008-09-12 |
2023-08-12 |
mouse |
| M-S Kwon, Y-J Seo, S-M Choi, J-K Lee, J-S Jung, S-H Park, H-W Su. The effect of formalin pretreatment on nicotine-induced antinociceptive effect: the role of mu-opioid receptor in the hippocampus. Neuroscience. vol 154. issue 2. 2008-08-29. PMID:18456411. |
in western blot assay, we examined s.c. formalin injection down-regulated mu-opioid receptor in the hippocampus after 40 h, and its effect was maintained for 1 week. |
2008-08-29 |
2023-08-12 |
Not clear |
| b' N Unsain, N Nu\\xc3\\xb1ez, A Anastas\\xc3\\xada, D H Masc\\xc3\\xb. Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: an initial event in neuronal injury induction. Neuroscience. vol 154. issue 3. 2008-08-29. PMID:18511210.' |
here, using western blot and immunohistochemistry analyses in the hippocampus, we found that 3-h se caused a remarkable decrease in trkb expression and phosphorylation, and a significant increase in p75ntr. |
2008-08-29 |
2023-08-12 |
Not clear |
| Michael E Calhoun, Bonnie R Fletcher, Stella Yi, Diana C Zentko, Michela Gallagher, Peter R Rap. Age-related spatial learning impairment is unrelated to spinophilin immunoreactive spine number and protein levels in rat hippocampus. Neurobiology of aging. vol 29. issue 8. 2008-08-21. PMID:17353069. |
by comparison, spinophilin protein levels in the hippocampus, measured by western blot analysis, failed to differ as a function of age. |
2008-08-21 |
2023-08-12 |
rat |
| Kenji Hashimoto, Yuko Fujita, Tamaki Ishima, Shigeyuki Chaki, Masaomi Iy. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 6. 2008-08-13. PMID:17804206. |
furthermore, western blot analysis revealed that levels of glyt-1 in the hippocampus, but not frontal cortex, of the pcp (10 mg/kg/day for 10 days)-treated mice were significantly higher than those of saline-treated mice. |
2008-08-13 |
2023-08-12 |
mouse |
| Raffaella Molteni, Matteo Pasini, Stefania Moraschi, Massimo Gennarelli, Filippo Drago, Giorgio Racagni, Marco A Riv. Reduced activation of intracellular signaling pathways in rat prefrontal cortex after chronic phencyclidine administration. Pharmacological research. vol 57. issue 4. 2008-07-29. PMID:18406625. |
western blot analysis has been performed to determine total and phospho-protein levels of extracellular signal-regulated kinases 1/2 (erk1/2), type ii calcium/calmodulin-dependent protein kinase (alphacamkii) and camp-response element binding protein (creb) in prefrontal cortex (pfc) and hippocampus (hip) of rat chronically treated with pcp, whereas their mrna levels were determined by real time rt-pcr. |
2008-07-29 |
2023-08-12 |
rat |
| K Sharma, Raj D Mehr. Long-term administration of estrogen or tamoxifen to ovariectomized rats affords neuroprotection to hippocampal neurons by modulating the expression of Bcl-2 and Bax. Brain research. vol 1204. 2008-07-22. PMID:18342840. |
the remaining animals in each group were utilized for protein and western blot analyses using unfixed hippocampal tissue. |
2008-07-22 |
2023-08-12 |
rat |