| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hilda Bajova, Thomas E Nelson, Donna L Gruo. Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture. Journal of neuroimmunology. vol 195. issue 1-2. 2008-07-10. PMID:18329727. |
in the current study, western blot analyses show that in rat hippocampal neuronal/glial cell cultures chronic cxcl10 increases the level of protein for erk1/2 as well as for the transcriptional factors creb and nf-kappab. |
2008-07-10 |
2023-08-12 |
rat |
| Andrea L O Hebb, Harold A Robertson, Eileen M Denovan-Wrigh. Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17913473. |
creb and pde10a protein levels in striatum and hippocampus were determined by western blot. |
2008-07-02 |
2023-08-12 |
mouse |
| Daejong Jeon, Inseon Song, William Guido, Karam Kim, Eunjoon Kim, Uhtaek Oh, Hee-Sup Shi. Ablation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memory. The Journal of biological chemistry. vol 283. issue 18. 2008-06-19. PMID:18339621. |
protein blot analysis showed a slight increase in the level of nmdar-2b in the mutant hippocampus. |
2008-06-19 |
2023-08-12 |
mouse |
| Wencheng Yang, Cheryl Leystra-Lantz, Michael J Stron. Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci). Brain research. vol 1196. 2008-05-30. PMID:18221734. |
the expression of gsk, cdk and p25/p35 was assayed in human frontal, hippocampal, cerebellar, cervical (dorsal and ventral) and lumbar (dorsal and ventral) tissue from neurologically intact control (5), als (5) or alsci (5) patients using rt-pcr, western blot or immunohistochemistry. |
2008-05-30 |
2023-08-12 |
human |
| Inês M Araújo, Joana M Gil, Bruno P Carreira, Paul Mohapel, Asa Petersen, Paulo S Pinheiro, Denis Soulet, Ben A Bahr, Patrik Brundin, Caetana M Carvalh. Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus. Journal of neurochemistry. vol 105. issue 3. 2008-05-22. PMID:18088374. |
immunohistochemistry and western blot analysis for the calpain-derived breakdown products of spectrin showed evidence of increased calpain activity in the same regions of the hippocampus where cell death is observed. |
2008-05-22 |
2023-08-12 |
rat |
| Natalia Jaworska, Suzanne M Dwyer, Benjamin Rusa. Repeated neonatal separation results in different neurochemical and behavioral changes in adult male and female Mongolian gerbils. Pharmacology, biochemistry, and behavior. vol 88. issue 4. 2008-05-08. PMID:18048094. |
western blot and optical densitometry measurements in the hippocampus did not reveal significant group differences in synaptophysin levels in either sex, but there was a tendency toward decreased levels of synaptophysin in the entire hippocampus as well as the ca1 hippocampal subregion of separated males. |
2008-05-08 |
2023-08-12 |
Not clear |
| Erik A Johnson, Kelly S Daugherty, Sarah J Gallagher, Anita V Moran, S Michelle DeFor. Glutamate receptor pathology is present in the hippocampus following repeated sub-lethal soman exposure in the absence of spatial memory deficits. Neurotoxicology. vol 29. issue 1. 2008-05-02. PMID:17942156. |
additionally, hippocampal lysates were probed for cytoskeletal, synaptic and glutamate receptor proteins using western blot analyses. |
2008-05-02 |
2023-08-12 |
Not clear |
| Keun W Park, Byung K Ji. Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: role of neuronal NADPH oxidase. Journal of neuroscience research. vol 86. issue 5. 2008-04-23. PMID:18183616. |
in addition, western blot analysis and double-label immunocytochemistry showed an up-regulation in the expression of cytosolic components (rac 1 and p67(phox)), the translocation of cytosolic proteins (p47(phox) and p67(phox)) to the membrane, and the localization of gp91(phox) or p47(phox) expression in hippocampal neurons of cultures and ca1 layer. |
2008-04-23 |
2023-08-12 |
Not clear |
| Y Oida, M Shimazawa, K Imaizumi, H Har. Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18082969. |
immunohistochemical and western blot analyses of the hippocampal cornet d'ammon (ca)1 subfield showed that bip expression was increased at 12 h, peaked at 3 days, then decreased (versus the control group). |
2008-04-22 |
2023-08-12 |
Not clear |
| Feng Guo, Na Yu, Ji-Qun Cai, Tim Quinn, Zhi-Hong Zong, Yan-Jun Zeng, Li-Ying Ha. Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat. Brain research bulletin. vol 75. issue 1. 2008-04-11. PMID:18158113. |
in this study, the mrna expressions of na(v)1.1, na(v)1.3 and beta(1) subunit in sers hippocampus were significantly higher than those in control rats hippocampus by real-time rt-pcr; the protein distributions and expressions of na(v)1.1, na(v)1.3 and beta(1) subunit in sers hippocampus were detected by immunofluorescence, immunohistochemistry and western blot, and the protein expressions of na(v)1.1, na(v)1.3 and beta(1) subunit were significantly increased. |
2008-04-11 |
2023-08-12 |
human |
| Joanna M Wierońska, Kinga Kłak, Agnieszka Pałucha, Piotr Brański, Andrzej Pil. Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex. Brain research. vol 1184. 2008-04-08. PMID:17976546. |
in the present study, the effects of chronic imipramine (10 mg/kg, 21 days) or citalopram (10 mg/kg, 21 days) treatment on the mglu4 or mglu7 receptors' protein levels in the frontal cortex and hippocampus of the rat brain were examined using the western blot analysis. |
2008-04-08 |
2023-08-12 |
rat |
| M Cachard-Chastel, S Devers, S Sicsic, M Langlois, F Lezoualc'h, A M Gardier, C Belzun. Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice. Behavioural brain research. vol 187. issue 2. 2008-04-07. PMID:18061284. |
western blot analysis of tissue homogenates in the cortex and hippocampus shows that sappalpha levels did not differ between saline- and scopolamine-treated mice. |
2008-04-07 |
2023-08-12 |
mouse |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
western blot analysis showed that nobiletin-stimulated phosphorylation of multiple protein kinase a (pka) substrates at 10 min following the treatment in cultured hippocampal neurons. |
2008-04-03 |
2023-08-12 |
Not clear |
| María Geraldina Bersier, Clara Peña, Georgina Rodríguez de Lores Arnai. The expression of NMDA receptor subunits in cerebral cortex and hippocampus is differentially increased by administration of endobain E, a Na+, K+-ATPase inhibitor. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17680361. |
the effect of endobain e on expression of nmda receptor subunits in membranes of rat cerebral cortex and hippocampus was analyzed by western blot. |
2008-04-01 |
2023-08-12 |
rat |
| Tyson B Brust, Francisco S Cayabyab, Brian A MacVica. C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:17967469. |
in support of our electrophysiological findings, western blot analysis showed that a1 receptor stimulation resulted in a transient increase in jnk phosphorylation in the membrane fraction of hippocampal lysates. |
2008-03-21 |
2023-08-12 |
rat |
| Noriyuki Akahoshi, Yoshiya L Murashima, Toshiyuki Himi, Yasuki Ishizaki, Isao Ishi. Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures. Neuroscience letters. vol 429. issue 2-3. 2008-03-04. PMID:17997037. |
western blot analysis of the hippocampal homogenates revealed that kainate induced a 3.3-fold increase in cathepsin s expression. |
2008-03-04 |
2023-08-12 |
mouse |
| Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain. vol 3. 2008-02-21. PMID:17974009. |
western blot analyses demonstrated that in the spinal cord, cfa also increased levels of phosphorylated camp response element-binding protein (creb), while in the hippocampus the activation of this transcription factor was significantly reduced, further suggesting that tissue specific transcription of either nk-1 or bdnf genes may be partially regulated by common intracellular transduction mechanisms mediated through activation of creb. |
2008-02-21 |
2023-08-12 |
rat |
| Fang Fang, Gengtao Li. A novel cyclic squamosamide analogue compound FLZ improves memory impairment in artificial senescence mice induced by chronic injection of D-galactose and NaNO2. Basic & clinical pharmacology & toxicology. vol 101. issue 6. 2008-01-29. PMID:17971066. |
immunoreactive cells of bcl-2 in the hippocampus were counted by immunohistochemical staining, and bcl-2 protein expression was analysed by western blot method. |
2008-01-29 |
2023-08-12 |
mouse |
| Ghanshyam N Pandey, Yogesh Dwivedi, Xinguo Ren, Hooriyah S Rizavi, Rosalinda C Roberts, Robert R Conle. Cyclic AMP response element-binding protein in post-mortem brain of teenage suicide victims: specific decrease in the prefrontal cortex but not the hippocampus. The international journal of neuropsychopharmacology. vol 10. issue 5. 2008-01-17. PMID:16978443. |
we determined cre-dna binding using the gel shift assay, as well as protein expression of creb using the western blot technique, and the mrna expression of creb using a quantitative reverse transcriptase-polymerase chain reaction (rt-pcr) technique in the prefrontal cortex (pfc), and hippocampus obtained from 17 teenage suicide victims and 17 matched normal control subjects. |
2008-01-17 |
2023-08-12 |
human |
| Mostofa Jamal, Kiyoshi Ameno, Uekita Ikuo, Mitsuru Kumihashi, Weihuan Wang, Iwao Ijir. Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain. Novartis Foundation symposium. vol 285. 2008-01-17. PMID:17590992. |
second, the effects of etoh and acetaldehyde on choline acetyltransferase (chat) and acetylcholinesterase (ache) were investigated in the frontal cortex and hippocampus of high acetaldehyde-producing rats using rt-pcr and western blot. |
2008-01-17 |
2023-08-12 |
rat |