| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuan-ying Li, Li Sun, Jie He, Zhao-li Chen, Fang Zhou, Xiao-yan Liu, Ruo-shan Li. The kappa-opioid receptor is upregulated in the spinal cord and locus ceruleus but downregulated in the dorsal root ganglia of morphine tolerant rats. Brain research. vol 1326. 2010-06-25. PMID:20206145. |
competitive real-time pcr, immunohistochemistry, and western blot analyses were used to assess kor expression in related regions of the nervous system, including the thalamus, hypothalamus, hippocampus, locus ceruleus (lc), periaqueductal gray (pag), lumber-sacral spinal cord, and dorsal root ganglia (drg). |
2010-06-25 |
2023-08-12 |
rat |
| Eduardo M Goto, Marcelo de Paula Silva, Sandra R Perosa, Gustavo A Argañaraz, João B Pesquero, Esper A Cavalheiro, Maria G Naffah-Mazzacoratti, Vicente P C Teixeira, José A Silv. Akt pathway activation and increased neuropeptide Y mRNA expression in the rat hippocampus: implications for seizure blockade. Neuropeptides. vol 44. issue 2. 2010-05-25. PMID:20064661. |
immunohistochemistry assay was employed to place ilk distribution in the hippocampus and western blot technique was used to determine akt activation level. |
2010-05-25 |
2023-08-12 |
rat |
| Afia Akram, James Schmeidler, Pavel Katsel, Patrick R Hof, Vahram Haroutunia. Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus. Brain research. vol 1318. 2010-05-20. PMID:20079340. |
to gain insight into atp-binding cassette transporter a1 (abca1) function and its potential role in ad pathology, we analyzed the expression of the cholesterol transporter abca1 in postmortem hippocampus from persons at different stages of dementia and ad associated neuropathology relative to cognitively intact normal donors by quantitative polymerase chain reaction (qpcr) and western blot. |
2010-05-20 |
2023-08-12 |
Not clear |
| Feng Guo, Feng Sun, Jun-Ling Yu, Qing-Hua Wang, Da-Yu Tu, Xiao-Yuan Mao, Rui Liu, Kun-Can Wu, Ni Xie, Li-Ying Hao, Ji-Qun Ca. Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus. Brain research bulletin. vol 81. issue 4-5. 2010-05-06. PMID:19853022. |
in this study, the glutamate concentration in sers hippocampus was increased compared with that of control rats by high performance liquid chromatography; the mrna expressions of glast and mglur1 in sers hippocampus were significantly lower than those in control rats hippocampus, whereas an abundant increase in mrna for glt-1 was observed by rt-pcr; eaac-1 and mglur1 protein in sers and control rats were localized widely in the hippocampus including ca1, ca3 and dentate gyrus regions by immunohistochemistry; the number of glast and mglur1-positive cells in the hippocampus of sers were less than those in control rats, especially for ca3 and dg region; the protein expression of glt-1 was up-regulated, but the protein expressions of glast and mglur1 were down-regulated in ser hippocampus by western blot. |
2010-05-06 |
2023-08-12 |
rat |
| Kara McNair, Rosemary Spike, Clare Guilding, George C Prendergast, Trevor W Stone, Stuart R Cobb, Brian J Morri. A role for RhoB in synaptic plasticity and the regulation of neuronal morphology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 9. 2010-05-05. PMID:20203211. |
in wild-type mice (rhob(+/+)), western blot analysis of potentiated hippocampus showed significant increases in phosphorylated cofilin relative to nonpotentiated slices, which were dramatically impaired in rhob(-/-) slices. |
2010-05-05 |
2023-08-12 |
mouse |
| Arianna Rinaldi, Sara Vincenti, Francesca De Vito, Irene Bozzoni, Alberto Oliverio, Carlo Presutti, Paola Fragapane, Andrea Mel. Stress induces region specific alterations in microRNAs expression in mice. Behavioural brain research. vol 208. issue 1. 2010-05-03. PMID:19913057. |
finally, northern blot analysis of the selected mirs on rna extracted from the hippocampus of stressed mice demonstrated that such changes were region specific, as no differences were observed in the hippocampus. |
2010-05-03 |
2023-08-12 |
mouse |
| Hongmei Shen, Ying Yuan, Fei Ding, Nan Hu, Jie Liu, Xiaosong G. Achyranthes bidentata polypeptides confer neuroprotection through inhibition of reactive oxygen species production, Bax expression, and mitochondrial dysfunction induced by overstimulation of N-methyl-D-aspartate receptors. Journal of neuroscience research. vol 88. issue 3. 2010-03-30. PMID:19774671. |
western blot analysis and colorimetric enzymatic assay demonstrated that abpp pretreatment inhibited nmda-induced increase of bax protein expression or caspase-3 activity in cultured hippocampal neurons. |
2010-03-30 |
2023-08-12 |
rat |
| Paul A Adlard, Jacqui M Parncutt, David I Finkelstein, Ashley I Bus. Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 5. 2010-03-05. PMID:20130173. |
these deficits are associated with significant alterations in key hippocampal proteins involved in learning and memory, as assessed by western blot. |
2010-03-05 |
2023-08-12 |
mouse |
| Keun W Park, Hyung H Baik, Byung K Ji. Interleukin-4-induced oxidative stress via microglial NADPH oxidase contributes to the death of hippocampal neurons in vivo. Current aging science. vol 1. issue 3. 2010-03-04. PMID:20021392. |
in parallel, western blot analysis and hydroethidine histochemistry revealed activation of nadph oxidase (as demonstrated by increased translocation of the cytosolic proteins p67(phox) and p47(phox)), generation of reactive oxygen species (ros), and oxidative damage in the hippocampal ca1 area, where degeneration of hippocampal neurons was evident. |
2010-03-04 |
2023-08-12 |
rat |
| Jun-De Zheng, Ai-Lian Hei, Ping-Ping Zuo, Yi-Long Dong, Xiao-Ning Song, Yasumitsu Takagi, Mutsuo Sekiguchi, Jian-Ping Ca. Age-related alterations in the expression of MTH2 in the hippocampus of the SAMP8 mouse with learning and memory deterioration. Journal of the neurological sciences. vol 287. issue 1-2. 2010-02-12. PMID:19735921. |
immunohistochemical and western blot analysis revealed that the level of mth2 protein in the hippocampus of the samp8 mouse progressively decreases beginning from four months after birth, whereas no such change was observed in the control senescence-accelerated resistant mouse 1 (samr1). |
2010-02-12 |
2023-08-12 |
mouse |
| Yin Gao, Xiubin Fang, He Sun, Yu Wang, Li Jie Yao, Jing Ping Li, Yue Tong, Baohui Zhang, Yuli Li. Toll-like receptor 4-mediated myeloid differentiation factor 88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in hippocampal CA1 region in mice. Biological & pharmaceutical bulletin. vol 32. issue 10. 2010-01-28. PMID:19801825. |
we determined the result of tlr4 antibodies-blocking and mice cerebral ischemia-reperfusion injuries by western blot, and evaluated neuronal damage in the hippocampus. |
2010-01-28 |
2023-08-12 |
mouse |
| Yangtao He, Wenqin Cai, Liyan Wang, Penghui Che. A developmental study on the expression of PDGFalphaR immunoreactive cells in the brain of postnatal rats. Neuroscience research. vol 65. issue 3. 2010-01-18. PMID:19665498. |
western blot analysis revealed that the expression of pdgfalphar in the cerebral cortex and hippocampus increased from p0 to p7 and then decreased gradually. |
2010-01-18 |
2023-08-12 |
rat |
| Haihong Li, Lei Zhang, Qingjun Huan. Differential expression of mitogen-activated protein kinase signaling pathway in the hippocampus of rats exposed to chronic unpredictable stress. Behavioural brain research. vol 205. issue 1. 2010-01-12. PMID:19576250. |
western blot of hippocampus showed that cus significantly decreased pcreb and pjnk levels, but there was no statistical difference between two groups in creb, erk1/2, perk1/2, p38, pp38 and jnk levels. |
2010-01-12 |
2023-08-12 |
rat |
| b' Grazyna Lietzau, Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Zbigniew Karwacki, Jerzy Dziewiatkowski, Ma\\xc5\\x82gorzata Witkowska, Justyna Sidor-Kaczmarek, Janusz Mory\\xc5\\x9. The molecular mechanisms of cell death in the course of transient ischemia are differentiated in evolutionary distinguished brain structures. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19693659.' |
using western blot, we studied changes in expression of caspases: 3, 8, 9, and aif in the frontoparietal neocortex, archicortex (ca1 and ca2 sectors of the hippocampus) and striatum, during reperfusion after 1 h occlusion of the middle cerebral artery. |
2009-12-30 |
2023-08-12 |
Not clear |
| Yukihiro Ohno, Shizuka Ishihara, Ryo Terada, Miki Kikuta, Nobumasa Sofue, Yoshiko Kawai, Tadao Serikawa, Masashi Sas. Preferential increase in the hippocampal synaptic vesicle protein 2A (SV2A) by pentylenetetrazole kindling. Biochemical and biophysical research communications. vol 390. issue 3. 2009-12-29. PMID:19751703. |
western blot analysis revealed that, among the secretary machinery proteins examined, hippocampal sv2a was selectively elevated by ptz kindling. |
2009-12-29 |
2023-08-12 |
mouse |
| Paula M Canas, João M N Duarte, Ricardo J Rodrigues, Attila Köfalvi, Rodrigo A Cunh. Modification upon aging of the density of presynaptic modulation systems in the hippocampus. Neurobiology of aging. vol 30. issue 11. 2009-12-07. PMID:18304697. |
thus, we now explored by western blot analysis how the density of different presynaptic markers and receptors changes with aging in rat hippocampal synaptosomes (purified nerve terminals). |
2009-12-07 |
2023-08-12 |
rat |
| Alessandra Tamburella, Vincenzo Micale, Andrea Navarria, Filippo Drag. Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: behavioral and neurochemical studies in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19596038. |
the expression of hippocampal neurotrophic factors, such as the brain-derived neurotrophic factor (bdnf), the phosphorilated camp response element-binding protein (p-creb), the b cell lymphoma-2 (bcl-2), the bax and the vascular endothelium growth factor (vegf) were also evaluated by western blot analysis. |
2009-11-17 |
2023-08-12 |
rat |
| Alessandra Tamburella, Vincenzo Micale, Andrea Navarria, Filippo Drag. Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: behavioral and neurochemical studies in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19596038. |
western blot analysis of hippocampal homogenates showed an enhancement of p-creb, bdnf bcl-2 and vegf protein levels in sl65.0155 treated groups, but not in citalopram or clomipramine treated groups, used here as positive control. |
2009-11-17 |
2023-08-12 |
rat |
| Keun W Park, Hyung H Baik, Byung K Ji. IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 7. 2009-11-16. PMID:19752235. |
in parallel, western blot analysis and hydroethidine histochemistry disclosed activation of nadph oxidase, generation of reactive oxygen species, and oxidative damage in the hippocampal ca1 area showing hippocampal neuron degeneration. |
2009-11-16 |
2023-08-12 |
Not clear |
| Xin Tang, Fei Ding, Yumin Yang, Nan Hu, Hong Wu, Xiaosong G. Evaluation on in vitro biocompatibility of silk fibroin-based biomaterials with primarily cultured hippocampal neurons. Journal of biomedical materials research. Part A. vol 91. issue 1. 2009-11-02. PMID:18780373. |
moreover, immunocytochemistry, rt-pcr, and western blot analysis revealed that no significant difference was found in mrna or protein levels of the growth-associated molecules, such as brain-derived neurotrophic factor, growth-associated protein-43, neurofilament, nerve growth factor, and nerve growth factor-receptor p75, between the hippocampal neurons cultured in the silk fibroin extract and in plain neuronal culture medium. |
2009-11-02 |
2023-08-12 |
Not clear |