| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anubhav Yadav, Shalini Dogra, Arun Kumar Boda, Poonam Kumari, Ajeet Kumar, Manish K Dash, Prem N Yada. Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor ACS chemical neuroscience. 2024-08-27. PMID:39190549. |
previously, we have shown that sustained kor activation leads to a trd-like phenotype in mice, and modulation of brain-derived neurotrophic factor (bdnf) expression in the prefrontal cortex (pfc) appears to be one of the molecular determinants of the antidepressant response. |
2024-08-27 |
2024-08-30 |
mouse |
| Nosarieme Omoregie Abey, Osaretin Albert Taiwo Ebuehi, Ngozi Awa Imag. Effect of perinatal dietary protein deficiency on some neurochemicals and cytoarchitectural balance, in F1 and F2 generations of rats. Nutritional neuroscience. vol 27. issue 9. 2024-08-27. PMID:37995096. |
bdnf and gdnf expression in the hippocampal and prefrontal (pfc) sections, immunohistochemical investigations of the morphological impact on the hippocampus and pfc, were also analyzed. |
2024-08-27 |
2024-08-30 |
rat |
| Nosarieme Omoregie Abey, Osaretin Albert Taiwo Ebuehi, Ngozi Awa Imag. Effect of perinatal dietary protein deficiency on some neurochemicals and cytoarchitectural balance, in F1 and F2 generations of rats. Nutritional neuroscience. vol 27. issue 9. 2024-08-27. PMID:37995096. |
bdnf and gdnf levels in the pfc were reduced in the 5%pd group. |
2024-08-27 |
2024-08-30 |
rat |
| B J Baranowski, A Mohammad, P J LeBlanc, V A Fajardo, R E K MacPherso. Examination of Akt and GSK3β in BDNF-mediated reductions in BACE1 activity in neuronal cells. Physiological reports. vol 12. issue 16. 2024-08-20. PMID:39161054. |
recently published work has demonstrated that bdnf reduces bace1 activity while also elevating the inhibition of gsk3β in the prefrontal cortex of male c57bl/6j mice. |
2024-08-20 |
2024-08-22 |
mouse |
| B J Baranowski, A Mohammad, P J LeBlanc, V A Fajardo, R E K MacPherso. Examination of Akt and GSK3β in BDNF-mediated reductions in BACE1 activity in neuronal cells. Physiological reports. vol 12. issue 16. 2024-08-20. PMID:39161054. |
an in vitro bace1 activity assay utilizing mouse prefrontal cortex (n = 6/group) supplemented with bdnf, bdnf + ana12 (trkb antagonist), or bdnf + wortmannin (akt inhibitor) demonstrated that bdnf reduced bace1 activity; however, in the presence of trkb or akt inhibition, this effect was abolished. |
2024-08-20 |
2024-08-22 |
mouse |
| B J Baranowski, A Mohammad, P J LeBlanc, V A Fajardo, R E K MacPherso. Examination of Akt and GSK3β in BDNF-mediated reductions in BACE1 activity in neuronal cells. Physiological reports. vol 12. issue 16. 2024-08-20. PMID:39161054. |
an in vitro adam10 activity assay utilizing mouse prefrontal cortex (n = 6/group) supplemented with bdnf, bdnf + ana12 (trkb antagonist), or bdnf + wortmannin (akt inhibitor) demonstrated that bdnf did not alter adam10 activity. |
2024-08-20 |
2024-08-22 |
mouse |
| Mohammad-Ali Samizadeh, Seyedeh-Tabassom Abdollahi-Keyvani, Hamed Fallah, Bahar Beigi, Atefeh Motamedi-Manesh, Sogand Adibian, Salar Vasegh. Sex difference alters the behavioral and cognitive performance in a rat model of schizophrenia induced by sub-chronic ketamine. Journal of psychiatric research. vol 178. 2024-08-15. PMID:39146821. |
in the present research, we aimed to investigate the effect of sub-chronic treatment of ketamine on cognitive and behavioral functions, and brain-derived neurotrophic factor (bdnf) expression level in the prefrontal cortex. |
2024-08-15 |
2024-08-18 |
rat |
| Mohammad-Ali Samizadeh, Seyedeh-Tabassom Abdollahi-Keyvani, Hamed Fallah, Bahar Beigi, Atefeh Motamedi-Manesh, Sogand Adibian, Salar Vasegh. Sex difference alters the behavioral and cognitive performance in a rat model of schizophrenia induced by sub-chronic ketamine. Journal of psychiatric research. vol 178. 2024-08-15. PMID:39146821. |
the results showed that ketamine injection for five consecutive days impaired the acquisition of long-term recognition memory and decreased bdnf level in the prefrontal cortex in both sexes. |
2024-08-15 |
2024-08-18 |
rat |
| Sonia Melgar-Locatelli, M Carmen Mañas-Padilla, Adriana Castro-Zavala, Patricia Rivera, María Del Carmen Razola-Díaz, Francisco J Monje, Celia Rodríguez-Pérez, Estela Castilla-Orteg. Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory. Food & function. 2024-07-29. PMID:39069830. |
adult hippocampal neurogenesis and brain-derived neurotrophic factor (bdnf) expression in the hippocampus and prefrontal cortex were evaluated using immunohistochemistry and western blot. |
2024-07-29 |
2024-08-02 |
mouse |
| Rujikan Chaisanam, Jintanaporn Wattanathorn, Wipawee Thukham-Mee, Nawanant Piyavhatkul, Pongsatorn Paholpa. Anxiolytic, Antidepression, and Memory-Enhancing Effects of the Novel Instant Soup RJ6601 in the Middle-Aged of Female Rats. Foods (Basel, Switzerland). vol 13. issue 14. 2024-07-27. PMID:39063255. |
the neuron density and levels of activities of ache, total mao, mao-a, mao-b, mda, sod, cat, gsh-px, il-1β, il-6, and bdnf in the prefrontal cortex at the end of study were also investigated. |
2024-07-27 |
2024-07-29 |
rat |
| Matheus Santos de Sousa Fernandes, Anderson Apolônio da Silva Pedroza, Deyvison Guilherme Martins Silva, Severina Cássia de Andrade Silva, Allifer R Pereira, Mariana P Fernandes, Fatma Hilal Yagin, Luca Paolo Ardigò, Claudia J Lagranh. Moderate aerobic training counterbalances the deleterious effect of undernutrition on oxidative balance and mitochondrial markers. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043767. |
at 60 days of life, the animals were sacrificed and the skeletal muscle, and prefrontal cortex (pfc) were removed to evaluate the oxidative metabolism markers and gene expression of atf-6, grp78, perk and bdnf. |
2024-07-23 |
2024-07-26 |
rat |
| Е М Кондаурова, A A Komarova, T V Ilchibaeva, A Ya Rodnyy, E A Zalivina, V S Naumenk. Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau protein. Vavilovskii zhurnal genetiki i selektsii. vol 28. issue 4. 2024-07-19. PMID:39027123. |
a decrease in the expression of the bdnf and ntrk2 genes in the prefrontal cortex was revealed after administration of aav-tau[r406w]. |
2024-07-19 |
2024-07-21 |
mouse |
| Éverton Renan Quaresma Dos Santos, Lucas Villar Pedrosa da Silva Pantoja, Sarah Viana Farias, Bruno Gonçalves Pinheiro, Eloisa Helena A Andrade, Paulo Fernando Santos Mendes, Jorddy Neves Cruz, Marta Chagas Monteiro, Kelly Davis, Rafael Rodrigues Lima, Jofre Jacob da Silva Freitas, Rommel Mário Rodríguez Burbano, Rui Daniel Prediger, Enéas Andrade Fontes-Junior, José Guilherme S Maia, Cristiane do Socorro Ferraz Mai. Linalool-rich rosewood essential oil (Aniba rosaeodora Ducke) mitigates emotional and neurochemical impairments induced by ethanol binge-like exposure during adolescence in female rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 178. 2024-07-18. PMID:39024836. |
twenty-four hours after treatments, it was evaluated the impact of ethanol exposure and rosewood oil treatment on the putative emotional impairments assessed on the splash and forced swimming tests, as well as the levels of brain-derived neurotrophic factor (bdnf), s100b, oxidative parameters, and inflammatory cytokines in prefrontal cortex and hippocampus. |
2024-07-18 |
2024-07-21 |
rat |
| Zahra Mashahadi, Hakimeh Saadati, Safa Ghaheri Far. Early-life manipulation of the serotonergic system exacerbates the harmful effects of sleep deprivation on cognitive functions. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-07-10. PMID:38984677. |
after the examination of the novel object recognition and passive avoidance memories, the hippocampi and prefrontal cortex were dissected to examine the brain-derived neurotrophic factor (bdnf) mrna expression by pcr. |
2024-07-10 |
2024-07-12 |
Not clear |
| Emilija Glavonic, Milorad Dragic, Milos Mitic, Minja Aleksic, Iva Lukic, Sanja Ivkovic, Miroslav Adzi. Ketamine's Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931336. |
ketamine also increased the akt and mtor activity and the glua1 and glun2a levels in the hpc and upregulated bdnf exon iv mrna expression in the hpc and pfc of the fear-extinguished mice. |
2024-06-27 |
2024-06-29 |
mouse |
| b' Merve Deniz De\\xc4\\x9firmenci, Hasan \\xc3\\x87al\\xc4\\xb1\\xc5\\x9fkan, Emel G\\xc3\\xbcne\\xc5\\x9. Effects of chronic intermittent cold stress on anxiety-depression-like behaviors in adolescent rats. Behavioural brain research. 2024-06-27. PMID:38936426.' |
cold stress resulted in decreased bdnf levels in the prefrontal cortex and striatum (p < 0.05), increased cortisol levels in the prefrontal cortex (p < 0.05), increased il-1β levels in the hippocampus and thalamus (p < 0.05), increased protein carbonyl levels in the striatum (p < 0.05), and decreased tas in the prefrontal cortex and thalamus (p < 0.05). |
2024-06-27 |
2024-06-30 |
human |
| Brian T Kipp, Polliana T Nunes, Lisa M Savag. Dysregulation of Neurotrophin Expression in Prefrontal Cortex and Nucleus Basalis Magnocellularis During and After Adolescent Intermittent Ethanol Exposure. Alcohol (Fayetteville, N.Y.). 2024-06-19. PMID:38897258. |
western blot analyses revealed that ethanol intoxication reduced the expression of bdnf and vesicular acetylcholine transporter (vacht) in the pfc, while ngf was lower in the nbm of aie treated animals. |
2024-06-19 |
2024-06-22 |
human |
| Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. |
additionally, it prevented bdnf depletion in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions), and mitigated astrogliosis and microgliosis in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions). |
2024-06-19 |
2024-06-22 |
mouse |
| Sierra J Stringfield, Erin K Kirschmann, Mary M Torregross. Working memory performance predicts, but does not reduce, cocaine- and cannabinoid-seeking in adult male rats. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853853. |
additionally, brain derived neurotrophic factor (bdnf) can facilitate plasticity in the prefrontal cortex and reduce drug-seeking behaviors. |
2024-06-10 |
2024-06-14 |
rat |
| Sierra J Stringfield, Erin K Kirschmann, Mary M Torregross. Working memory performance predicts, but does not reduce, cocaine- and cannabinoid-seeking in adult male rats. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853853. |
we investigated whether working memory training could elevate bdnf levels in the prefrontal cortex and if this training would predict or protect against cocaine or cannabinoid seeking. |
2024-06-10 |
2024-06-14 |
rat |