| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Fumagalli, L Madaschi, L Caffino, G Marfia, A M Di Giulio, G Racagni, A Gori. Acute spinal cord injury reduces brain derived neurotrohic factor expression in rat hippocampus. Neuroscience. vol 159. issue 3. 2009-09-21. PMID:19344636. |
we have found that acute sci reduced bdnf expression selectively in the hippocampus of lesioned rats, a decrease which persists at least 1 week, thus identifying the modulation of the neurotrophin biosynthesis as an important mechanism underlying brain vulnerability to sci. |
2009-09-21 |
2023-08-12 |
rat |
| F Fumagalli, L Madaschi, L Caffino, G Marfia, A M Di Giulio, G Racagni, A Gori. Acute spinal cord injury reduces brain derived neurotrohic factor expression in rat hippocampus. Neuroscience. vol 159. issue 3. 2009-09-21. PMID:19344636. |
these data are the first to show that sci alters hippocampal bdnf expression and identify the neurotrophin as a potential target through which sci changes brain functions, a notion that might prove useful in understanding the mechanisms underlying brain vulnerability to sci. |
2009-09-21 |
2023-08-12 |
rat |
| Olaf Schulte-Herbrüggen, Eberhard Fuchs, Nashat Abumaria, Annerose Ziegler, Heidi Danker-Hopfe, Christoph Hiemke, Rainer Hellwe. Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress. Journal of neuroscience research. vol 87. issue 11. 2009-09-21. PMID:19360902. |
the left hippocampus revealed significantly higher amounts of bdnf (2.5-fold increase) protein than the right hippocampus. |
2009-09-21 |
2023-08-12 |
rat |
| Mathew Blurton-Jones, Masashi Kitazawa, Hilda Martinez-Coria, Nicholas A Castello, Franz-Josef Müller, Jeanne F Loring, Tritia R Yamasaki, Wayne W Poon, Kim N Green, Frank M LaFerl. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 32. 2009-09-21. PMID:19633196. |
instead, the mechanism underlying the improved cognition involves a robust enhancement of hippocampal synaptic density, mediated by brain-derived neurotrophic factor (bdnf). |
2009-09-21 |
2023-08-12 |
mouse |
| Mathew Blurton-Jones, Masashi Kitazawa, Hilda Martinez-Coria, Nicholas A Castello, Franz-Josef Müller, Jeanne F Loring, Tritia R Yamasaki, Wayne W Poon, Kim N Green, Frank M LaFerl. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 32. 2009-09-21. PMID:19633196. |
furthermore, loss-of-function studies show that depletion of nsc-derived bdnf fails to improve cognition or restore hippocampal synaptic density. |
2009-09-21 |
2023-08-12 |
mouse |
| Clarissa M Comim, Lisiane Tuon, Laura Stertz, Mariz Vainzof, Flávio Kapczinski, João Queved. Striatum brain-derived neurotrophic factor levels are decreased in dystrophin-deficient mice. Neuroscience letters. vol 459. issue 2. 2009-09-14. PMID:19422882. |
the present study investigated bdnf protein levels by elisa analysis in prefrontal cortex, cerebellum, hippocampus, striatum and cortex tissues from male dystrophic mdx (n=5) and normal c57bl10 mouse (n=5). |
2009-09-14 |
2023-08-12 |
mouse |
| J M Gatt, C B Nemeroff, C Dobson-Stone, R H Paul, R A Bryant, P R Schofield, E Gordon, A H Kemp, L M William. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular psychiatry. vol 14. issue 7. 2009-09-10. PMID:19153574. |
in addition, significant bdnf-els interactions indicated that bdnf met carriers exposed to greater els have smaller hippocampal and amygdala volumes (p=0.013), heart rate elevations (p=0.0002) and a decline in working memory (p=0.022). |
2009-09-10 |
2023-08-12 |
human |
| César Renato Sartori, Fernanda Campos Pelágio, Simone Aparecida Teixeira, Verónica Sandra Valentinuzzi, André Luiz Nascimento, Fábio Rogério, Marcelo Nicolás Muscará, Elenice Aparecida de Moraes Ferrari, Francesco Langon. Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus. Behavioural brain research. vol 203. issue 2. 2009-09-10. PMID:19397936. |
physical activity and seizures have been associated with enhanced hippocampal expression of bdnf, indicating that this protein may have a dual role in epilepsy. |
2009-09-10 |
2023-08-12 |
mouse |
| César Renato Sartori, Fernanda Campos Pelágio, Simone Aparecida Teixeira, Verónica Sandra Valentinuzzi, André Luiz Nascimento, Fábio Rogério, Marcelo Nicolás Muscará, Elenice Aparecida de Moraes Ferrari, Francesco Langon. Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus. Behavioural brain research. vol 203. issue 2. 2009-09-10. PMID:19397936. |
after that, the spatial memory and the expression of the precursor and mature forms of hippocampal bdnf were assessed. |
2009-09-10 |
2023-08-12 |
mouse |
| César Renato Sartori, Fernanda Campos Pelágio, Simone Aparecida Teixeira, Verónica Sandra Valentinuzzi, André Luiz Nascimento, Fábio Rogério, Marcelo Nicolás Muscará, Elenice Aparecida de Moraes Ferrari, Francesco Langon. Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus. Behavioural brain research. vol 203. issue 2. 2009-09-10. PMID:19397936. |
these results show that voluntary physical activity improved the spatial memory and increased the hippocampal content of mature bdnf of mice with pilocarpine-induced status epilepticus. |
2009-09-10 |
2023-08-12 |
mouse |
| Takefumi Kikusui, Sozo Ichikawa, Yuji Mor. Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice. Psychoneuroendocrinology. vol 34. issue 5. 2009-08-25. PMID:19167168. |
maternal deprivation by early weaning increases corticosterone and decreases hippocampal bdnf and neurogenesis in mice. |
2009-08-25 |
2023-08-12 |
mouse |
| Takefumi Kikusui, Sozo Ichikawa, Yuji Mor. Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice. Psychoneuroendocrinology. vol 34. issue 5. 2009-08-25. PMID:19167168. |
early-weaned males, but not females, had less brain-derived neurotrophic factor (bdnf) protein in the hippocampus at 3 weeks of age than standard-weaned mice. |
2009-08-25 |
2023-08-12 |
mouse |
| Takefumi Kikusui, Sozo Ichikawa, Yuji Mor. Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice. Psychoneuroendocrinology. vol 34. issue 5. 2009-08-25. PMID:19167168. |
these results suggest that lack of mother-infant interaction during the late lactation period leads to an increase in corticosterone synthesis for 2 days and a decrease in bdnf synthesis in males; moreover, this lack of interaction transiently inhibits hippocampal cell proliferation and survival in both males and females, although the effects were more pronounced in males. |
2009-08-25 |
2023-08-12 |
mouse |
| Akiko Kurata, Shigeru Morinobu, Manabu Fuchikami, Shigeto Yamamoto, Shigeto Yamawak. Maternal postpartum learned helplessness (LH) affects maternal care by dams and responses to the LH test in adolescent offspring. Hormones and behavior. vol 56. issue 1. 2009-08-21. PMID:19341740. |
plasma corticosterone (cort) levels, hippocampal levels of glucocorticoid receptor (gr) and brain-derived neurotrophic factor (bdnf) mrna were measured before and after the lh test in offspring. |
2009-08-21 |
2023-08-12 |
human |
| Ge Li, Elaine R Peskind, Steven P Millard, Peter Chi, Izabela Sokal, Chang-En Yu, Lynn M Bekris, Murray A Raskind, Douglas R Galasko, Thomas J Montin. Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects. PloS one. vol 4. issue 5. 2009-08-17. PMID:19412541. |
brain-derived neurotrophic factor (bdnf) is an activity-dependent secreted protein that is critical to organization of neuronal networks and synaptic plasticity, especially in the hippocampus. |
2009-08-17 |
2023-08-12 |
human |
| Jennifer L Larimore, Christopher A Chapleau, Shinichi Kudo, Anne Theibert, Alan K Percy, Lucas Pozzo-Mille. Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiology of disease. vol 34. issue 2. 2009-08-04. PMID:19217433. |
bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by rett-associated mecp2 mutations. |
2009-08-04 |
2023-08-12 |
human |
| Betty Zimmerberg, Hannah E Foote, Tracey A Van Kempe. Olfactory association learning and brain-derived neurotrophic factor in an animal model of early deprivation. Developmental psychobiology. vol 51. issue 4. 2009-08-04. PMID:19308959. |
learning the odor association, as revealed in a position preference for the novel odor, was accompanied by an increase in hippocampal bdnf in o/m subjects from undisturbed control litters. |
2009-08-04 |
2023-08-12 |
human |
| Betty Zimmerberg, Hannah E Foote, Tracey A Van Kempe. Olfactory association learning and brain-derived neurotrophic factor in an animal model of early deprivation. Developmental psychobiology. vol 51. issue 4. 2009-08-04. PMID:19308959. |
ed subjects did not make the classically conditioned odor association and did not show an increase in hippocampal bdnf. |
2009-08-04 |
2023-08-12 |
human |
| Darrick T Balu, Georgia E Hodes, Brian T Anderson, Irwin Luck. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19177066. |
protein levels of brain-derived neurotrophic factor (bdnf) in mrl/mpj mice were elevated significantly in the frontal cortex, hippocampus, and amygdala after chronic flx treatment, but increased only in the frontal cortex by chronic dmi. |
2009-08-03 |
2023-08-12 |
mouse |
| Darrick T Balu, Georgia E Hodes, Brian T Anderson, Irwin Luck. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19177066. |
in contrast, bdnf levels in c57bl/6j mice were decreased in the hippocampus and increased in the amygdala after chronic flx, and were decreased in the brain stem after chronic dmi. |
2009-08-03 |
2023-08-12 |
mouse |