| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Nicol\\xc3\\xa1s Unsain, Laura Ester Montroull, Daniel Hugo Masc\\xc3\\xb. Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus. Journal of neurochemistry. vol 111. issue 2. 2009-10-22. PMID:19686240.' |
brain-derived neurotrophic factor (bdnf) is involved in many aspects of neuronal biology and hippocampal physiology. |
2009-10-22 |
2023-08-12 |
human |
| Britta Haenisch, Andras Bilkei-Gorzo, Marc G Caron, Heinz Bönisc. Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression. Journal of neurochemistry. vol 111. issue 2. 2009-10-22. PMID:19694905. |
chronic stress caused down-regulation of bdnf, nerve growth factor, and neurotrophin-3 in hippocampus and cerebral cortex and up-regulation of these targets in striatal regions. |
2009-10-22 |
2023-08-12 |
mouse |
| Y Yu, Q Wang, X-F Huan. Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice. Neuroscience. vol 160. issue 2. 2009-10-21. PMID:19217934. |
using in situ hybridization, dio mice had significantly decreased levels of bdnf mrna expression (-32% to -37%) and trkb (-21% to -23%) in the hippocampus compared to dr mice on an hf diet, but not on energy-restricted pair-feeding and lf diets. |
2009-10-21 |
2023-08-12 |
mouse |
| Y Yu, Q Wang, X-F Huan. Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice. Neuroscience. vol 160. issue 2. 2009-10-21. PMID:19217934. |
these findings suggest that decreased hippocampal bdnf and trkb expression plays an important role in high-fat diet induced obesity. |
2009-10-21 |
2023-08-12 |
mouse |
| Grace Sophia Griesbach, David Allen Hovda, Fernando Gomez-Pinill. Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation. Brain research. vol 1288. 2009-10-15. PMID:19555673. |
we have previously shown that voluntary exercise upregulates brain derived neurotrophic factor (bdnf) within the hippocampus and is associated with an enhancement of cognitive recovery after a lateral fluid percussion injury (fpi). |
2009-10-15 |
2023-08-12 |
rat |
| Roberto Toro, Marie Chupin, Line Garnero, Gabriel Leonard, Michel Perron, Bruce Pike, Alain Pitiot, Louis Richer, Suzanne Veillette, Zdenka Pausova, Tomás Pau. Brain volumes and Val66Met polymorphism of the BDNF gene: local or global effects? Brain structure & function. vol 213. issue 6. 2009-10-12. PMID:19205731. |
a common single-nucleotide polymorphism in the brain-derived neurotrophic factor (bdnf) gene coding the val66met substitution in the pro-bdnf protein has been associated with a number of behavioural and neuroanatomical phenotypes; the latter include, for example, regional differences in volumes of the hippocampus and prefrontal grey matter. |
2009-10-12 |
2023-08-12 |
Not clear |
| Camin Dean, Huisheng Liu, F Mark Dunning, Payne Y Chang, Meyer B Jackson, Edwin R Chapma. Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release. Nature neuroscience. vol 12. issue 6. 2009-10-09. PMID:19448629. |
we found that syt-iv localized to brain-derived neurotrophic factor (bdnf)-containing vesicles in hippocampal neurons. |
2009-10-09 |
2023-08-12 |
mouse |
| Yu-Fan Liu, Hsiun-ing Chen, Chao-Liang Wu, Yu-Min Kuo, Lung Yu, A-Min Huang, Fong-Sen Wu, Jih-Ing Chuang, Chauying J Je. Differential effects of treadmill running and wheel running on spatial or aversive learning and memory: roles of amygdalar brain-derived neurotrophic factor and synaptotagmin I. The Journal of physiology. vol 587. issue Pt 13. 2009-10-09. PMID:19451201. |
brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and synaptotagmin i (syt i), in hippocampus and amygdala were determined by elisa or immunoblotting. |
2009-10-09 |
2023-08-12 |
mouse |
| Synphen H Wu, Juan Carlos Arévalo, Federica Sarti, Lino Tessarollo, Wen-Biao Gan, Moses V Cha. Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Developmental neurobiology. vol 69. issue 9. 2009-10-08. PMID:19449316. |
here we report that a substrate of bdnf signaling, the ankyrin repeat-rich membrane spanning (arms) protein or kidins220, plays a critical role in the branching of cortical and hippocampal dendrites and in the turnover of cortical spines. |
2009-10-08 |
2023-08-12 |
mouse |
| Hervé Fiorentino, Nicola Kuczewski, Diabe Diabira, Nadine Ferrand, Menelas N Pangalos, Christophe Porcher, Jean-Luc Gaiars. GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 37. 2009-10-02. PMID:19759312. |
using whole-cell patch-clamp recordings on newborn mouse hippocampi lacking functional gaba(b) receptors (gaba(b)-rs) and time-lapse fluorescence imaging on cultured hippocampal neurons expressing gfp-tagged brain-derived neurotrophic factor (bdnf), we found that activation of metabotropic gaba(b) receptors (gaba(b)-rs) triggers secretion of bdnf and promotes the development of perisomatic gabaergic synapses in the newborn mouse hippocampus. |
2009-10-02 |
2023-08-12 |
mouse |
| Michael D Hammonds, Seong S Shi. Effects of 4-week treatment with lithium and olanzapine on levels of brain-derived neurotrophic factor, B-cell CLL/lymphoma 2 and phosphorylated cyclic adenosine monophosphate response element-binding protein in the sub-regions of the hippocampus. Basic & clinical pharmacology & toxicology. vol 105. issue 2. 2009-09-29. PMID:19486334. |
to understand a common molecular mechanism underlying the neuroplastic actions of lithium and olanzapine, we assessed the effect of 4-week lithium and olanzapine treatment on the levels of bdnf, bcl-2 and cyclic adenosine monophosphate response element-binding protein (creb), a transcription factor involved in expression of bdnf and bcl-2, in the dentate gyrus and hippocampal area ca1. |
2009-09-29 |
2023-08-12 |
Not clear |
| Nikola N Lucas, Diane W Le. BDNF increases BrdU-IR cells in the injured adult zebra finch hippocampus. Neuroreport. vol 20. issue 12. 2009-09-29. PMID:19512953. |
bdnf increases brdu-ir cells in the injured adult zebra finch hippocampus. |
2009-09-29 |
2023-08-12 |
Not clear |
| Nikola N Lucas, Diane W Le. BDNF increases BrdU-IR cells in the injured adult zebra finch hippocampus. Neuroreport. vol 20. issue 12. 2009-09-29. PMID:19512953. |
to address this, adult male zebra finches received bilateral hippocampal lesions by infusing saline into one hemisphere and bdnf into the other. |
2009-09-29 |
2023-08-12 |
Not clear |
| Nikola N Lucas, Diane W Le. BDNF increases BrdU-IR cells in the injured adult zebra finch hippocampus. Neuroreport. vol 20. issue 12. 2009-09-29. PMID:19512953. |
a greater number of brdu-immunoreactive (brdu-ir) cells were observed in the bdnf-treated hemisphere in the hippocampus, but not in the septum or stem cell-rich subventricular zone, indicating that bdnf promoted localized cell proliferation and incorporation at the injury site only. |
2009-09-29 |
2023-08-12 |
Not clear |
| Marko Sallert, Tomi Rantamäki, Aino Vesikansa, Heidi Anthoni, Kirsi Harju, Jari Yli-Kauhaluoma, Tomi Taira, Eero Castren, Sari E Laur. Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 36. 2009-09-28. PMID:19741136. |
application of bdnf in neonate hippocampal slices resulted in increase in synaptic transmission that fully occluded the immature-type kar activity in area ca1. |
2009-09-28 |
2023-08-12 |
Not clear |
| Phu V Tran, Stephanie J B Fretham, Erik S Carlson, Michael K Georgief. Long-term reduction of hippocampal brain-derived neurotrophic factor activity after fetal-neonatal iron deficiency in adult rats. Pediatric research. vol 65. issue 5. 2009-09-24. PMID:19190544. |
fetal-neonatal iron deficiency acutely alters hippocampal biochemistry, neural morphology, and electrophysiology accompanied by a downregulation of brain-derived neurotrophic factor (bdnf). |
2009-09-24 |
2023-08-12 |
rat |
| Phu V Tran, Stephanie J B Fretham, Erik S Carlson, Michael K Georgief. Long-term reduction of hippocampal brain-derived neurotrophic factor activity after fetal-neonatal iron deficiency in adult rats. Pediatric research. vol 65. issue 5. 2009-09-24. PMID:19190544. |
collectively, fetal-neonatal iron deficiency lowers hippocampal bdnf expression and function beyond the period of iron deficiency. |
2009-09-24 |
2023-08-12 |
rat |
| Li-he Jiang, Yan Shi, Li-sheng Wang, Zhi-rong Yan. The influence of orally administered docosahexaenoic acid on cognitive ability in aged mice. The Journal of nutritional biochemistry. vol 20. issue 9. 2009-09-21. PMID:18829287. |
the protein levels of bdnf in hippocampus tissue were assessed by western blotting. |
2009-09-21 |
2023-08-12 |
mouse |
| Li-he Jiang, Yan Shi, Li-sheng Wang, Zhi-rong Yan. The influence of orally administered docosahexaenoic acid on cognitive ability in aged mice. The Journal of nutritional biochemistry. vol 20. issue 9. 2009-09-21. PMID:18829287. |
the results showed that the cognitive capability of mice was significantly different between the dha-treated groups and the control group; the protein level of bdnf was significantly increased in the hippocampus; the levels of no and da were significantly increased in hippocampus and striatum tissues. |
2009-09-21 |
2023-08-12 |
mouse |
| Li-he Jiang, Yan Shi, Li-sheng Wang, Zhi-rong Yan. The influence of orally administered docosahexaenoic acid on cognitive ability in aged mice. The Journal of nutritional biochemistry. vol 20. issue 9. 2009-09-21. PMID:18829287. |
in conclusion, during aging, dha supplementation can improve the cognitive function in mice and can increase the protein level of bdnf in hippocampus tissue and the levels of no and da in hippocampus and striatum tissues. |
2009-09-21 |
2023-08-12 |
mouse |