| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Yang, Yu Pei, Yan-Li Pan, Jun Jia, Chen Shi, Yan Yu, Jia-Hui Deng, Bo Li, Xiao-Li Gong, Xuan Wang, Xiao-Min Wang, Xin M. Enhanced antidepressant-like effects of electroacupuncture combined with citalopram in a rat model of depression. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-07-04. PMID:23737815. |
further investigations revealed that 2 hz ea plus 5 mg/kg citalopram produced a remarkably increased expression of bdnf and its receptor trkb in the hippocampus compared with those measured in the vehicle group. |
2013-07-04 |
2023-08-12 |
rat |
| S Ceccatelli, R Bose, K Edoff, N Onishchenko, S Spulbe. Long-lasting neurotoxic effects of exposure to methylmercury during development. Journal of internal medicine. vol 273. issue 5. 2013-07-02. PMID:23600401. |
the behavioural alterations were associated with a decreased number of proliferating cells and lower expression of brain-derived neurotrophic factor (bdnf) mrna in the hippocampal dentate gyrus. |
2013-07-02 |
2023-08-12 |
mouse |
| Ying Xie, Xi Huang, Sui-yu Hu, Ying-jin Zhang, Yang Wang, Xin-jian Qiu, Ping Ren, Rong Fan, Chun-hu Zhang, Wei-bin Xie, Hui Ji, Juan He, Xiao Chen, Linhong Xie, Zhao-qian Liu, Hong-hao Zho. The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate. Amino acids. vol 44. issue 2. 2013-07-01. PMID:22782214. |
(3) fst enhanced hippocampal erk1/2, p-erk1/2 and bdnf expression levels. |
2013-07-01 |
2023-08-12 |
rat |
| Ying Xie, Xi Huang, Sui-yu Hu, Ying-jin Zhang, Yang Wang, Xin-jian Qiu, Ping Ren, Rong Fan, Chun-hu Zhang, Wei-bin Xie, Hui Ji, Juan He, Xiao Chen, Linhong Xie, Zhao-qian Liu, Hong-hao Zho. The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate. Amino acids. vol 44. issue 2. 2013-07-01. PMID:22782214. |
mh (9 mg/kg) treatment further up-regulated hippocampal p-erk1/2 and bdnf expression levels, and this effect was prevented by nbqx. |
2013-07-01 |
2023-08-12 |
rat |
| Ying Xie, Xi Huang, Sui-yu Hu, Ying-jin Zhang, Yang Wang, Xin-jian Qiu, Ping Ren, Rong Fan, Chun-hu Zhang, Wei-bin Xie, Hui Ji, Juan He, Xiao Chen, Linhong Xie, Zhao-qian Liu, Hong-hao Zho. The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate. Amino acids. vol 44. issue 2. 2013-07-01. PMID:22782214. |
(5) in vitro experiments, we found that incubation of rats hippocampus slices with mh (10, 20 μm respectively) increased concentrations of bdnf and p-erk1/2. |
2013-07-01 |
2023-08-12 |
rat |
| Julie Brossaud, Hélène Roumes, Marie-Pierre Moisan, Véronique Pallet, Anabelle Redonnet, Jean-Benoît Corcuf. Retinoids and glucocorticoids target common genes in hippocampal HT22 cells. Journal of neurochemistry. vol 125. issue 4. 2013-07-01. PMID:23398290. |
we investigated proteins involved either in the signaling pathways [ra receptor β (rarβ) and glucocorticoid receptor (gr)] or in neuron differentiation and plasticity [tissue transglutaminase 2 (ttg) and brain-derived neurotrophic factor (bdnf)] in a hippocampal cell line, ht22. |
2013-07-01 |
2023-08-12 |
Not clear |
| Sinead M Gibney, Barry McGuinness, Christine Prendergast, Andrew Harkin, Thomas J Conno. Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression. Brain, behavior, and immunity. vol 28. 2013-06-28. PMID:23201589. |
these behavioural changes were accompanied by decreased expression of bdnf and trkb in hippocampus and frontal cortex. |
2013-06-28 |
2023-08-12 |
rat |
| Yi-Wei Tsai, Yea-Ru Yang, Synthia H Sun, Keng-Chen Liang, Ray-Yau Wan. Post ischemia intermittent hypoxia induces hippocampal neurogenesis and synaptic alterations and alleviates long-term memory impairment. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 5. 2013-06-28. PMID:23443175. |
hippocampal neo-neurons expressed bdnf and exhibited enhanced presynaptic function as indicated by increases in the psynapsin expression, synaptophysin intensity, and postsynapse density following ih intervention after ischemia. |
2013-06-28 |
2023-08-12 |
Not clear |
| Yi-Wei Tsai, Yea-Ru Yang, Synthia H Sun, Keng-Chen Liang, Ray-Yau Wan. Post ischemia intermittent hypoxia induces hippocampal neurogenesis and synaptic alterations and alleviates long-term memory impairment. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 5. 2013-06-28. PMID:23443175. |
our results suggest that postischemia ih intervention rescued ischemia-induced spatial learning and memory impairment by inducing hippocampal neurogenesis and functional synaptogenesis via bdnf expression. |
2013-06-28 |
2023-08-12 |
Not clear |
| Dong-Ho Kwon, Bum-Soo Kim, Hyukki Chang, Young-In Kim, Sangmee Ahn Jo, Yea-Hyun Lee. Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level. Biochemical and biophysical research communications. vol 434. issue 2. 2013-06-28. PMID:23535373. |
we verified the relationship between oxidative stress and bdnf signaling by treating primary hippocampal cultures with hydrogen peroxide (h2o2), which reduced bdnf and phosphorylated creb and akt (p-creb, p-akt) in a dose-dependent manner. |
2013-06-28 |
2023-08-12 |
Not clear |
| Dong-Ho Kwon, Bum-Soo Kim, Hyukki Chang, Young-In Kim, Sangmee Ahn Jo, Yea-Hyun Lee. Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level. Biochemical and biophysical research communications. vol 434. issue 2. 2013-06-28. PMID:23535373. |
these findings suggest that chronic exercise can ameliorate repeated stress-induced cognitive impairment by detoxifying reactive oxygen species (ros) in the hippocampus and activating bdnf signaling. |
2013-06-28 |
2023-08-12 |
Not clear |
| Sa Rang Oh, Su-Jin Kim, Dong Hyun Kim, Jong Hoon Ryu, Eun-Mi Ahn, Ji Wook Jun. Angelica keiskei ameliorates scopolamine-induced memory impairments in mice. Biological & pharmaceutical bulletin. vol 36. issue 1. 2013-06-26. PMID:23132631. |
additionally, ak significantly recovered the phosphorylation of creb and expression of bdnf reduced by scopolamine in the hippocampus. |
2013-06-26 |
2023-08-12 |
mouse |
| Fatemeh Tanehkar, Ali Rashidy-Pour, Abbas Ali Vafaei, Hamid Reza Sameni, Saeed Haghighi, Hossien Miladi-Gorji, Fereshteh Motamedi, Maziar Mohammad Akhavan, Kowsar Bavarsa. Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats. Hormones and behavior. vol 63. issue 1. 2013-06-24. PMID:23068768. |
we also investigated the effects of nd and voluntary exercise on hippocampal bdnf levels. |
2013-06-24 |
2023-08-12 |
rat |
| Fatemeh Tanehkar, Ali Rashidy-Pour, Abbas Ali Vafaei, Hamid Reza Sameni, Saeed Haghighi, Hossien Miladi-Gorji, Fereshteh Motamedi, Maziar Mohammad Akhavan, Kowsar Bavarsa. Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats. Hormones and behavior. vol 63. issue 1. 2013-06-24. PMID:23068768. |
exercise significantly improved performance during both the training and retention of the water maze task, and enhanced hippocampal bdnf. |
2013-06-24 |
2023-08-12 |
rat |
| Fatemeh Tanehkar, Ali Rashidy-Pour, Abbas Ali Vafaei, Hamid Reza Sameni, Saeed Haghighi, Hossien Miladi-Gorji, Fereshteh Motamedi, Maziar Mohammad Akhavan, Kowsar Bavarsa. Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats. Hormones and behavior. vol 63. issue 1. 2013-06-24. PMID:23068768. |
nd also potentiated the exercise-induced increase in hippocampal bdnf levels. |
2013-06-24 |
2023-08-12 |
rat |
| Lei Liu, Bingjin Li, Yang Zhou, Liang Wang, Fang Tang, Dongyuan Shao, Xiulan Jiang, Hui Zhao, Ranji Cui, Yuxin L. Antidepressant-like effect of Fuzi total alkaloid on ovariectomized mice. Journal of pharmacological sciences. vol 120. issue 4. 2013-06-21. PMID:23196901. |
further experiments showed that fuzi total alkaloid enhanced the ratio of phospho-creb/creb (camp response element-binding) and bdnf (brain-derived neurotrophic factor) protein level in the frontal cortex and hippocampus in ovariectomized mice but not in normal mice. |
2013-06-21 |
2023-08-12 |
mouse |
| Min Chul Lee, Masahiro Okamoto, Yu Fan Liu, Koshiro Inoue, Takashi Matsui, Haruo Nogami, Hideaki Soy. Voluntary resistance running with short distance enhances spatial memory related to hippocampal BDNF signaling. Journal of applied physiology (Bethesda, Md. : 1985). vol 113. issue 8. 2013-06-17. PMID:22936723. |
voluntary resistance running with short distance enhances spatial memory related to hippocampal bdnf signaling. |
2013-06-17 |
2023-08-12 |
rat |
| Min Chul Lee, Masahiro Okamoto, Yu Fan Liu, Koshiro Inoue, Takashi Matsui, Haruo Nogami, Hideaki Soy. Voluntary resistance running with short distance enhances spatial memory related to hippocampal BDNF signaling. Journal of applied physiology (Bethesda, Md. : 1985). vol 113. issue 8. 2013-06-17. PMID:22936723. |
here, we examined whether rwr would have potential effects on hippocampal cognitive functions with enhanced hippocampal brain-derived neurotrophic factor (bdnf), as does wheel running without a load (wr). |
2013-06-17 |
2023-08-12 |
rat |
| Min Chul Lee, Masahiro Okamoto, Yu Fan Liu, Koshiro Inoue, Takashi Matsui, Haruo Nogami, Hideaki Soy. Voluntary resistance running with short distance enhances spatial memory related to hippocampal BDNF signaling. Journal of applied physiology (Bethesda, Md. : 1985). vol 113. issue 8. 2013-06-17. PMID:22936723. |
both rwr and wr led to improved spatial learning and memory as well as gene expressions of hippocampal bdnf signaling-related molecules. |
2013-06-17 |
2023-08-12 |
rat |
| Min Chul Lee, Masahiro Okamoto, Yu Fan Liu, Koshiro Inoue, Takashi Matsui, Haruo Nogami, Hideaki Soy. Voluntary resistance running with short distance enhances spatial memory related to hippocampal BDNF signaling. Journal of applied physiology (Bethesda, Md. : 1985). vol 113. issue 8. 2013-06-17. PMID:22936723. |
rwr increased hippocampal bdnf, tyrosine-related kinase b (trkb), and camp response element-binding (creb) protein levels, whereas wr increased only bdnf. |
2013-06-17 |
2023-08-12 |
rat |