All Relations between bdnf and hippocampus

Publication Sentence Publish Date Extraction Date Species
D K Avrova, L V Bayunova, N F Avrova, I O Zakharov. The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury. Bulletin of experimental biology and medicine. 2024-06-21. PMID:38907060. the expression of neurotrophic factor bdnf in the ca1 region of hippocampus did not differ in sham-operated rats and animals exposed to ischemia/reperfusion. 2024-06-21 2024-06-24 rat
Xiaoyu Wang, Qian Pang, Jiangqi Hu, Bin Luo, Yunping Lu, Xu Sun, Shixiang Meng, Qingsong Jian. Cognitive decline in Sprague-Dawley rats induced by neuroplasticity changes after occlusal support loss. CNS neuroscience & therapeutics. vol 30. issue 6. 2024-06-20. PMID:38898731. the most well-known function of the hippocampus is learning and memory, and the mechanism behind is neuroplasticity, which strongly depends on the level of brain-derived neurotrophic factor (bdnf). 2024-06-20 2024-06-22 rat
Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. icv-stz induced a reduction in viable cells, depletion of bdnf, and triggered astrogliosis and microgliosis in the cortex and hippocampus. 2024-06-19 2024-06-22 mouse
Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. additionally, it prevented bdnf depletion in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions), and mitigated astrogliosis and microgliosis in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions). 2024-06-19 2024-06-22 mouse
Mira Hamze, Cathy Brier, Emmanuelle Buhler, Jinwei Zhang, Igor Medina, Christophe Porche. Regulation of Neuronal Chloride Homeostasis by Pro- and Mature Brain-Derived Neurotrophic Factor (BDNF) via KCC2 Cation-Chloride Cotransporters in Rat Cortical Neurons. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892438. we investigated the interplay between both forms of bdnf and chloride homeostasis in rat hippocampal neurons and in utero electroporated cortices of rat pups, spanning the behavioral, cellular, and molecular levels. 2024-06-19 2024-06-21 rat
Changjian Wan, Lulu Shi, Yuying Lai, Zhuhong Wu, Mingzhe Zou, Zhibin Liu, Wei Meng, Songhua Wan. Long-term voluntary running improves cognitive ability in developing mice by modulating the cholinergic system, antioxidant ability, and BDNF/PI3K/Akt/CREB pathway. Neuroscience letters. 2024-06-18. PMID:38889879. additionally, exercise also upregulated the expression of brain-derived neurotrophic factor (bdnf), tropomyosin receptor kinase b (trkb), phosphoinositide 3 kinases (pi3k), akt, camp response element-binding protein (creb), and phosphorylated camp response element-binding protein (p-creb) in the hippocampus. 2024-06-18 2024-06-21 mouse
Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. this study aims to determine the effect of chronic meth administration on the expression of bdnf protein using immunohistochemistry in the rat frontal cortex and hippocampus. 2024-06-17 2024-06-21 rat
Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. the results showed that hippocampal ca1 bdnf protein was significantly increased by 72 % above control values in the ed-binge rats, while other hippocampal regions and frontal cortex were not significantly affected. 2024-06-17 2024-06-21 rat
Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. the hippocampal bdnf increase may reflect an initial increase in a protective factor produced in response to elevated glutamate release resulting in neurodegenerative excitotoxicity. 2024-06-17 2024-06-21 rat
Shiyan Zhang, Boya Gu, Kai Zhen, Liwen Du, Yuanyuan Lv, Laikang Y. Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis. Archives of gerontology and geriatrics. vol 126. 2024-06-15. PMID:38878598. in addition, exercise significantly increased bdnf levels in the hippocampus (smd = 0.92, p< 0.00001) and cortex (smd = 1.56, p= 0.02) of ad models. 2024-06-15 2024-06-18 Not clear
Shiyan Zhang, Boya Gu, Kai Zhen, Liwen Du, Yuanyuan Lv, Laikang Y. Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis. Archives of gerontology and geriatrics. vol 126. 2024-06-15. PMID:38878598. exercise, especially treadmill exercise, swimming, and voluntary wheel running, significantly increased bdnf levels in hippocampus and cortex of ad models, with swimming being the most effective intervention type. 2024-06-15 2024-06-18 Not clear
Caíque Olegário Diniz E Magalhães, Ricardo Augusto Leoni De Sousa, Bruno Ferreira Mendes, Isabela Rocha Dias, Ramona Ramalho Souza Pereira, Gabriela Cruz Pereira, Kil Sun Lee, Marco Fabricio Dias Peixoto, Ricardo Cardoso Cassilha. Accumulated HIIT inhibits anxiety and depression, improves cognitive function, and memory-related proteins in the hippocampus of aged rats. Experimental brain research. 2024-06-12. PMID:38864869. rats were euthanized, and the hippocampus was harvested for western blot analyses (camkii and bdnf). 2024-06-12 2024-06-14 rat
Ashrakt H Abdelhamid, Eman M Mantawy, Riham S Said, Ebtehal El-Demerdas. Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway. Toxicology and applied pharmacology. 2024-06-10. PMID:38857790. furthermore, saxa boosted hippocampal neurogenesis by upregulating brain-derived neurotrophic factor (bdnf) expression. 2024-06-10 2024-06-14 rat
Ayman Alzu'bi, Ejlal Abu-El-Rub, Fatimah Almahasneh, Lena Tahat, Rabaa Y Athamneh, Ramada Khasawneh, Hiba Alzoubi, Doaa S Ghorab, Rawan Almazari, Mazhar Salim Al Zoubi, Raed M Al-Zoub. Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice. Neurotoxicology. vol 103. 2024-06-08. PMID:38823587. these findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (bdnf), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. 2024-06-08 2024-06-11 mouse
Hiroyoshi Harada, Masayoshi Mori, Yusuke Murata, Yuri Kohno, Kazuki Terada, Kenji Ohe, Munechika Enjoj. Divergent effects of chronic continuous and intermittent social defeat stress on emotional behaviors: Impact on phosphorylated CREB and BDNF protein levels in the rat hippocampus. Neuroscience letters. 2024-06-05. PMID:38838971. conversely, is resulted in increased anxiety-like behavior and behavioral despair alongside decreased levels of phosphorylated creb and bdnf, particularly in the dorsal hippocampus. 2024-06-05 2024-06-08 rat
Hiroyoshi Harada, Masayoshi Mori, Yusuke Murata, Yuri Kohno, Kazuki Terada, Kenji Ohe, Munechika Enjoj. Divergent effects of chronic continuous and intermittent social defeat stress on emotional behaviors: Impact on phosphorylated CREB and BDNF protein levels in the rat hippocampus. Neuroscience letters. 2024-06-05. PMID:38838971. divergent effects of chronic continuous and intermittent social defeat stress on emotional behaviors: impact on phosphorylated creb and bdnf protein levels in the rat hippocampus. 2024-06-05 2024-06-08 rat
Hiroyoshi Harada, Masayoshi Mori, Yusuke Murata, Yuri Kohno, Kazuki Terada, Kenji Ohe, Munechika Enjoj. Divergent effects of chronic continuous and intermittent social defeat stress on emotional behaviors: Impact on phosphorylated CREB and BDNF protein levels in the rat hippocampus. Neuroscience letters. 2024-06-05. PMID:38838971. however, whether stress episodes divergently could affect hippocampal cyclic amp response element-binding protein (creb)-brain-derived neurotrophic factor (bdnf) signaling remains unclear, a key regulator of psychiatric symptoms. 2024-06-05 2024-06-08 rat
Mikhail Yu Stepanichev, Diana I Mamedova, Natalia V Gulyaev. Hippocampus under Pressure: Molecular Mechanisms of Development of Cognitive Impairments in SHR Rats. Biochemistry. Biokhimiia. vol 89. issue 4. 2024-06-04. PMID:38831507. changes in multiple biochemical glucocorticoid-dependent processes in the hippocampus, including dysfunction of steroid hormones receptors, impairments of neurotransmitter systems, bdnf deficiency, oxidative stress, and neuroinflammation are accompanied by the structural alterations, such as cellular signs of neuroinflammation micro- and astrogliosis, impairments of neurogenesis in the subgranular neurogenic zone, and neurodegenerative processes at the level of synapses, axons, and dendrites up to the death of neurons. 2024-06-04 2024-06-06 rat
Youjin Wang, Dong Peng, Xiang Zhang, Jiayan Chen, Jianfeng Feng, Runze Zhang, Wanwen Mai, Hongxia Chen, Yan Yang, Yadong Huang, Qihao Zhan. PLCβ4 driven by cadmium-exposure during gestation and lactation contributes to cognitive deficits by suppressing PIP2/PLCγ1/CREB/BDNF signaling pathway in male offspring. Journal of hazardous materials. vol 474. 2024-05-31. PMID:38820747. the decreased activation of plcγ1 inhibited the phosphorylation of creb to reduce bdnf transcription, which consequently resulted in the damage of hippocampal neurons and cognitive deficiency. 2024-05-31 2024-06-02 rat
Youjin Wang, Dong Peng, Xiang Zhang, Jiayan Chen, Jianfeng Feng, Runze Zhang, Wanwen Mai, Hongxia Chen, Yan Yang, Yadong Huang, Qihao Zhan. PLCβ4 driven by cadmium-exposure during gestation and lactation contributes to cognitive deficits by suppressing PIP2/PLCγ1/CREB/BDNF signaling pathway in male offspring. Journal of hazardous materials. vol 474. 2024-05-31. PMID:38820747. moreover, the low level of bdnf promoted aep activation to induce aβ deposition in the hippocampus. 2024-05-31 2024-06-02 rat