| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Peña, L Thompson-Snipes, P R Calkins, N Tatevian, M Puppi, M J Finegol. Alterations in myeloid dendritic cell innate immune responses in the Galphai2-deficient mouse model of colitis. Inflammatory bowel diseases. vol 15. issue 2. 2009-07-23. PMID:19037851. |
the g protein alpha subunit type-2 (galpha(i)2)-deficient mouse develops inflammatory bowel disease (ibd) with increased severity in mice on a 129svev (129) background compared to the c57bl/6 (b6) background. |
2009-07-23 |
2023-08-12 |
mouse |
| Christine G DiRienzo, George F Murphy, Thea M Friedman, Robert Korngol. T-cell receptor V(alpha) usage by effector CD4+Vbeta11+ T cells mediating graft-versus-host disease directed to minor histocompatibility antigens. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. vol 13. issue 3. 2007-06-14. PMID:17317580. |
polymerase chain reaction (pcr)-based complementarity-determining region 3 (cdr3)-sized spectratype analysis of b6 vbeta11(+) t cells from the spleens of recipient balb.b mice undergoing gvhd indicated biased use within the v(alpha)6, 9, 13, 14, 18, and 22 families. |
2007-06-14 |
2023-08-12 |
mouse |
| Christine G DiRienzo, George F Murphy, Thea M Friedman, Robert Korngol. T-cell receptor V(alpha) usage by effector CD4+Vbeta11+ T cells mediating graft-versus-host disease directed to minor histocompatibility antigens. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. vol 13. issue 3. 2007-06-14. PMID:17317580. |
to probe deeper into this limited v(alpha) response, the current study was undertaken to further define trav-jalpha (traj) nucleotide sequences found in host-presensitized b6 vbeta11(+) t cells proliferating in response to in vitro stimulation with balb.b splenocytes. |
2007-06-14 |
2023-08-12 |
mouse |
| Geri R Brown, Edward L Lee, Jihad El-Hayek, Katherine Kintner, Cheryl Luc. IL-12-independent LIGHT signaling enhances MHC class II disparate CD4+ T cell alloproliferation, IFN-gamma responses, and intestinal graft-versus-host disease. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 8. 2005-05-17. PMID:15814693. |
an inhibitor protein of light and lt alpha beta2 (lt beta r-ig) and an inhibitor protein of light (hvem-ig) caused similar decreases in alloresponses of control b6 or b6.129s1-il12rb2(tm1jm) (b6.il12r-/-) spleen cells (spc) in a mhc class ii-disparate mlc. |
2005-05-17 |
2023-08-12 |
Not clear |
| Hong Xu, Beate G Exner, Paula M Chilton, Carrie Schanie, Suzanne T Ildsta. CD45 congenic bone marrow transplantation: evidence for T cell-mediated immunity. Stem cells (Dayton, Ohio). vol 22. issue 6. 2005-04-01. PMID:15536194. |
when b6 tcr beta(-/-), tcr delta(-/-), or tcr beta(-/-)/delta(-/-) (cd45.2) mice were transplanted with cd45.1 bone marrow, significantly enhanced engraftment occurred in recipients lacking alpha beta-tcr(+) t cells (p < .00005). |
2005-04-01 |
2023-08-12 |
mouse |
| Andrew I Webb, Natalie A Borg, Michelle A Dunstone, Lars Kjer-Nielsen, Travis Beddoe, James McCluskey, Francis R Carbone, Stephen P Bottomley, Marie-Isabel Aguilar, Anthony W Purcell, Jamie Rossjoh. The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 1. 2004-08-17. PMID:15210799. |
the altered dynamics of arg(62), coupled with a small rigid-body movement in the alpha(1) helix encompassing this residue, correlated with biased valpha usage in the b6 mice. |
2004-08-17 |
2023-08-12 |
mouse |
| C A F von Arnim, E Verstege, M W Riep. Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus. Neuroscience letters. vol 365. issue 3. 2004-08-09. PMID:15246542. |
we investigated mrna expression of known markers of hypoxic tolerance by a semiquantitative rt-pcr (adenosine receptors (a1 and a3), nitric oxide synthases (enos and nnos), app production, progesterone receptor, and estrogen receptors alpha and beta) in cd-1, c3h, and b6 mice. |
2004-08-09 |
2023-08-12 |
mouse |
| Kelly B Reilly, Suseela Srinivasan, Melissa E Hatley, Mary Kim Patricia, Joanne Lannigan, David T Bolick, George Vandenhoff, Hong Pei, Rama Natarajan, Jerry L Nadler, Catherine C Hedric. 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo. The Journal of biological chemistry. vol 279. issue 10. 2004-07-06. PMID:14676201. |
in a series of blocking studies, antibodies to alpha(4) and beta(2) integrins in wehi monocytes blocked monocyte adhesion to both lotg and b6 control ec. |
2004-07-06 |
2023-08-12 |
mouse |
| E Allison Green, Leonid Gorelik, Catrin M McGregor, Elise H Tran, Richard A Flavel. CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 19. 2003-10-29. PMID:12949259. |
transgenic expression of tumor necrosis factor alpha from birth to 25 days of age in the islets of b6 mice that constitutively express cd80 on their beta cells results in accumulation of cd4+cd25+tgf-beta+ cells exclusively in the islets and pancreatic lymph nodes, which delays diabetes progression. |
2003-10-29 |
2023-08-12 |
mouse |
| Zoran Kurepa, Jie Su, James Forma. Memory phenotype of CD8+ T cells in MHC class Ia-deficient mice. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 11. 2003-09-02. PMID:12759416. |
in contrast to b6 animals, most of the cd8 t cells from these mice have a memory phenotype (cd44(high)cd122(high) cd62l(low)) including both cd8 alpha beta and cd8 alpha alpha subsets. |
2003-09-02 |
2023-08-12 |
mouse |
| Tamara Krajina, Frank Leithäuser, Peter Möller, Zlatko Trobonjaca, Jörg Reiman. Colonic lamina propria dendritic cells in mice with CD4+ T cell-induced colitis. European journal of immunology. vol 33. issue 4. 2003-05-07. PMID:12672074. |
cd4(+) alpha beta t cells from normal or mhc class ii-deficient b6 mice transferred into congenic rag1(-/-) hosts induce a progressive, lethal colitis. |
2003-05-07 |
2023-08-12 |
mouse |
| L Graves, A Dalvi, I Lucki, J A Blendy, T Abe. Behavioral analysis of CREB alphadelta mutation on a B6/129 F1 hybrid background. Hippocampus. vol 12. issue 1. 2002-10-04. PMID:11918283. |
mice with targeted deletions of two creb isoforms (alpha and delta; creb alphadelta mice) have been characterized on a mixed genetic background of c57bl/6 (b6) and 129/svev (129), as well as on a defined f1 hybrid of b6 and fvb/n, and these results suggest that the phenotype of creb alphadelta mice depends critically on genetic background. |
2002-10-04 |
2023-08-12 |
mouse |
| Amalia Sapag, Johan Wouters, Christophe Lambert, Pablo de Ioannes, Jaime Eyzaguirre, Eric Depiereu. The endoxylanases from family 11: computer analysis of protein sequences reveals important structural and phylogenetic relationships. Journal of biotechnology. vol 95. issue 2. 2002-05-08. PMID:11911922. |
four boxes defining segments of highest similarity were detected; they correspond to regions of defined secondary structure: b5, b6, b8 and the carboxyl end of the alpha helix, respectively. |
2002-05-08 |
2023-08-12 |
Not clear |
| Yoshiaki Shimizu, Julie A Margenthaler, Keith Landeros, Naoki Otomo, Gerard Doherty, M Wayne Fly. The resistance of P. acnes--primed interferon gamma-deficient mice to low-dose lipopolysaccharide-induced acute liver injury. Hepatology (Baltimore, Md.). vol 35. issue 4. 2002-04-17. PMID:11915026. |
although low-dose (20 microg) lps alone had no effect on survival, the administration of 800 microg lps alone resulted in 100% mortality in both b6 and gko mice without significant hepatic mononuclear cellular infiltration or differences in elevated plasma tumor necrosis factor alpha (tnf-alpha), interleukin 6 (il-6), and il-12 levels. |
2002-04-17 |
2023-08-12 |
mouse |
| Z Trobonjaca, F Leithäuser, P Möller, H Bluethmann, Y Koezuka, H R MacDonald, J Reiman. MHC-II-independent CD4+ T cells induce colitis in immunodeficient RAG-/- hosts. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 6. 2001-05-17. PMID:11238623. |
cd4(+) alpha beta t cells from either normal c57bl/6 (b6) or mhc-ii-deficient (a alpha(-/-) or a beta(-/-)) b6 donor mice engrafted into congenic immunodeficient rag1(-/-) b6 hosts induced an aggressive inflammatory bowel disease (ibd). |
2001-05-17 |
2023-08-12 |
mouse |
| Z Trobonjaca, F Leithäuser, P Möller, H Bluethmann, Y Koezuka, H R MacDonald, J Reiman. MHC-II-independent CD4+ T cells induce colitis in immunodeficient RAG-/- hosts. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 6. 2001-05-17. PMID:11238623. |
ibd-associated clp th1 cd4(+) t cell populations were polyclonal and mhc-ii-restricted when derived from normal b6 donor mice, but oligoclonal and apparently mhc-i-restricted when derived from mhc-ii-deficient (a alpha(-/-) or a beta(-/-)) b6 donor mice. |
2001-05-17 |
2023-08-12 |
mouse |
| X L Rudner, K A Kernacki, R P Barrett, L D Hazlet. Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulates macrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 12. 2000-07-20. PMID:10843717. |
the kinetics of il-1 (alpha and beta) production after pseudomonas aeruginosa corneal infection was examined in susceptible (cornea perforates) c57bl/6j (b6) and resistant (cornea heals) balb/cbyj (balb/c) mice. |
2000-07-20 |
2023-08-12 |
mouse |
| P K Mehta, P Christe. The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes. Advances in enzymology and related areas of molecular biology. vol 74. 2000-07-12. PMID:10800595. |
family profile analysis of amino acid sequences supported by comparison of the available three-dimensional (3-d) crystal structures indicates that the b6 enzymes known to date belong to four independent evolutionary lineages of homologous (or more precisely paralogous) proteins, of which the alpha family is by far the largest. |
2000-07-12 |
2023-08-12 |
Not clear |
| D B Drachman, K R McIntosh, B Yan. Factors that determine the severity of experimental myasthenia gravis. Annals of the New York Academy of Sciences. vol 841. 1998-08-04. PMID:9668247. |
these considerations have led to the following scheme, illustrated diagrammatically in figure 2, to explain the differences in eamg in b6 and bm12 mice: (1) the mhc class ii of b6 mice binds the alpha 146-162 peptide of torpedo achr with high affinity, while the genetically altered mhc class ii of bm12 mice does not, as previously suggested (see figure 2). |
1998-08-04 |
2023-08-12 |
mouse |
| D B Drachman, K R McIntosh, B Yan. Factors that determine the severity of experimental myasthenia gravis. Annals of the New York Academy of Sciences. vol 841. 1998-08-04. PMID:9668247. |
(2) the alpha 146-162/mhc class ii complex occurs only in b6 mice and interacts with t cells having appropriate tcrs, resulting in their stimulation and expansion. |
1998-08-04 |
2023-08-12 |
mouse |