| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chaohui Lisa Zhao, Amy Rapkiewicz, Mona Maghsoodi-Deerwester, Mala Gupta, Wenqing Cao, Thomas Palaia, Jianhong Zhou, Bebu Ram, Duc Vo, Behnam Rafiee, Zarrin Hossein-Zadeh, Bahram Dabiri, Iman Hann. Pathological findings in the postmortem liver of patients with coronavirus disease 2019 (COVID-19). Human pathology. vol 109. 2021-04-05. PMID:33307078. |
we collected the clinical data from 17 autopsy cases of patients with covid-19 including age, sex, body mass index (bmi), liver function test (alanine aminotransaminase (alt), aspartate aminotransaminase (ast), alkaline phosphatase (alp), direct bilirubin, and total bilirubin), d-dimer, and anticoagulation treatment. |
2021-04-05 |
2023-08-13 |
Not clear |
| Chunmiao Jiang, Cunhui Fan, Xinbo Yu, Tao Xu, Jia Cai, Xiaoyu Fan, Jie Zhan. Comparison of the efficacy of different periodic periodontal scaling protocols for oral hygiene in adolescents with fixed orthodontic appliances: A prospective cohort study. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. vol 159. issue 4. 2021-04-05. PMID:33573896. |
the purpose of this reseach was to compare the effects of different periodic periodontal scaling protocols on the periodontal health of adolescents with fixed orthodontic appliances by assessing the aspartate aminotransferase (ast) and alkaline phosphatase (alp) levels in gingival crevicular fluid and periodontal clinical indexes in a prospective cohort study. |
2021-04-05 |
2023-08-13 |
Not clear |
| Tadatoshi Ohtaki, Kanae Ogata, Hiroshi Kajikawa, Toshiaki Sumiyoshi, Sanae Asano, Shigehisa Tsumagari, Tetsuya Horikit. Effect of high-concentrate corn grain diet-induced elevated ruminal lipopolysaccharide levels on dairy cow liver function. The Journal of veterinary medical science. vol 82. issue 7. 2021-04-01. PMID:32461536. |
in the hc group, the hp levels and aspartate transaminase (ast) activity were significantly higher and the total cholesterol levels were significantly lower after high-concentrate diet feeding than before feeding. |
2021-04-01 |
2023-08-13 |
cattle |
| Adil Farooq Wali, Muneeb U Rehman, Mohammad Raish, Mohsin Kazi, Padma G M Rao, Osamah Alnemer, Parvaiz Ahmad, Ajaz Ahma. Zingerone [4-(3-Methoxy-4-hydroxyphenyl)-butan-2] Attenuates Lipopolysaccharide-Induced Inflammation and Protects Rats from Sepsis Associated Multi Organ Damage. Molecules (Basel, Switzerland). vol 25. issue 21. 2021-04-01. PMID:33158114. |
the blood samples were collected and used for the analysis of biochemical parameters like alanine transaminase (alt), alkaline phosphatase (alp), aspartate transaminase (ast), blood urea nitrogen (bun), cr, urea, lactate dehydrogenase (ldh), albumin, bilirubin (bil), and total protein. |
2021-04-01 |
2023-08-13 |
rat |
| Satyanarayana R Pondugula, Mohammed Majrashi, Mohammed Almaghrabi, Kodye Abbott, Manoj Govindarajulu, Sindhu Ramesh, Kristina Gill, Eddie Fahoury, Natasha Narayanan, Darshini Desai, Rishi Nadar, Edwin McElroy, Timothy Moore, Muralikrishnan Dhanasekara. Predictable hematological markers associated with cognitive decline in valid rodent models of cognitive impairment. Toxicology mechanisms and methods. vol 30. issue 6. 2021-03-31. PMID:32329394. |
there was a significant increase in creatinine kinase, lactate dehydrogenase and aspartate aminotransferase (ast) in the chemotherapy group. |
2021-03-31 |
2023-08-13 |
human |
| Michel Rayar, Jean-Marie Beaurepaire, Emma Bajeux, Stéphanie Hamonic, Thomas Renard, Clara Locher, Véronique Desfourneaux, Aude Merdrignac, Damien Bergeat, Mohamed Lakehal, Laurent Sulpice, Pauline Houssel-Debry, Caroline Jezequel, Christophe Camus, Edouard Bardou-Jacquet, Bernard Meunie. Hypothermic Oxygenated Perfusion Improves Extended Criteria Donor Liver Graft Function and Reduces Duration of Hospitalization Without Extra Cost: The PERPHO Study. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 27. issue 3. 2021-03-31. PMID:33237618. |
immediately after lt, the median aspartate aminotransferase (ast) level was significantly lower in the hope group (724ui versus 1284ui; p = 0.046) as were the alanine aminotransferase (alt; 392ui versus 720ui; p = 0.01), lactate (2.2 versus 2.7; p = 0.01) there was a significant reduction in intensive care unit stay (3 versus 5 days; p = 0.01) and hospitalization (15 versus 20 days; p = 0.01). |
2021-03-31 |
2023-08-13 |
Not clear |
| Maruthanayagam Alaguprathana, Mani Poonkotha. Haematological, biochemical, enzymological and histological responses of Labeo rohita exposed to methyl orange dye solution treated with Oedogonium subplagiostomum AP1. Environmental science and pollution research international. vol 28. issue 14. 2021-03-31. PMID:33400116. |
the behavioural response, mortality, haematological (red blood corpuscles (rbc), packed cell volume (pcv), haemoglobin (hb), white blood corpuscles (wbc), mean corpuscular volume (mcv), mean corpuscular haemoglobin (mch) and mean corpuscular haemoglobin concentration (mchc)), biochemical (plasma glucose and protein), enzymological (aspartate amino transaminases (ast) and alanine amino transaminases (alt)) and histological examination (gills, liver and kidney) of labeo rohita are exposed to untreated and treated methyl orange dye solutions were assessed on 7th day. |
2021-03-31 |
2023-08-13 |
Not clear |
| Johanna Winter, Max M Lenders, Maximilian Gassenmaier, Andrea Forschner, Ulrike Leiter, Benjamin Weide, Mette-Triin Purde, Lukas Flatz, Antonio Cozzio, Martin Röcken, Claus Garbe, Thomas K Eigentler, Nikolaus B Wagne. Prognostic role of gamma-glutamyl transferase in metastatic melanoma patients treated with immune checkpoint inhibitors. Cancer immunology, immunotherapy : CII. vol 70. issue 4. 2021-03-30. PMID:33113003. |
in contrast to the liver transaminases alanine aminotransferase (alt) and aspartate aminotransferase (ast), only little is known about the frequency and impact of gamma-glutamyl transferase (ggt) elevations. |
2021-03-30 |
2023-08-13 |
Not clear |
| Kai Kang, Yue Sun, Dan Pan, Li-Xuan Sang, Ming-Jun Sun, Yi-Ling Li, Bing Chan. Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic-associated fatty liver disease in mice. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-30. PMID:33777186. |
after 8 weeks, the levels of plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), total cholesterol (tc), lipopolysaccharide (lps), tumor necrosis factor (tnf)-α, interleukin (il)-6, il-1β and il-10 were assessed and h&e staining of mouse liver tissue was performed. |
2021-03-30 |
2023-08-13 |
mouse |
| Prabin Khatri, Aryan Neupane, Suman Raj Sapkota, Bibhav Bashyal, Dipesh Sharma, Ashmita Chhetri, K C Chirag, Ashish Banjade, Priyanka Sapkota, Subarna Bhandar. Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma. Case reports in hepatology. vol 2021. 2021-03-30. PMID:33777462. |
the standard liver function test measures alanine aminotransferase (alt), aspartate aminotransferase (ast), alanine phosphatase (alp), bilirubin levels (total, direct, and indirect), proteins (total protein and albumin), and pt-inr (prothrombin time and international normalized ratio). |
2021-03-30 |
2023-08-13 |
Not clear |
| Amit Kundu, Prasanta Dey, Jae Hyeon Park, In Su Kim, Seung Jun Kwack, Hyung Sik Ki. EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats. Cells. vol 9. issue 5. 2021-03-29. PMID:32365537. |
in this study, ex-527 (5 µg/kg), administered to hfd rats twice a week for ten weeks, reduced the serum levels of triglyceride (tg), total cholesterol, alanine aminotransferase (alt), and aspartate aminotransferase (ast) and attenuated hepatic fibrosis evidenced by masson's trichrome and hepatic fat by oil red-o staining. |
2021-03-29 |
2023-08-13 |
human |
| Weidong Qin, Wenwu Bai, Keyin Liu, Ya Liu, Xiao Meng, Kai Zhang, Mingxiang Zhan. Clinical Course and Risk Factors of Disease Deterioration in Critically Ill Patients with COVID-19. Human gene therapy. vol 32. issue 5-6. 2021-03-29. PMID:33412996. |
the levels of aspartate transaminase (ast), brain natriuretic peptide (bnp), creatine kinase isoenzyme mb (ck-mb), lactate dehydrogenase (ldh), and c-reactive protein (crp) were also significantly increased in the nonsurviving group. |
2021-03-29 |
2023-08-13 |
Not clear |
| Domenico Ferro, Francesco Baratta, Daniele Pastori, Nicholas Cocomello, Alessandra Colantoni, Francesco Angelico, Maria Del Be. New Insights into the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Gut-Derived Lipopolysaccharides and Oxidative Stress. Nutrients. vol 12. issue 9. 2021-03-26. PMID:32927776. |
in addition, many antibiotics have regulatory effects on intestinal microbiota and were able to reduce serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and tumor necrosis factor alpha (tnf-α) in nash animal models. |
2021-03-26 |
2023-08-13 |
human |
| Mishah Azhar, Muhammad Hammami, Ahmad Musmar, Matthew Brome. Glycogen Hepatopathy: A Reversible yet Relapsing Cause of Hepatitis in Type 1 Diabetics. Cureus. vol 13. issue 2. 2021-03-26. PMID:33763324. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) had ranged from 100's to over 7000 u/l while alkaline phosphatase (alp) was elevated to over 400 iu/l. albumin, total bilirubin, platelets, international normalized ratio (inr), eosinophils, viral hepatitis panel, antinuclear antibody (ana), smooth muscle antibody (ab), anti-liver-kidney microsomal (lkm) ab, celiac serologies, ceruloplasmin, alpha 1 antitrypsin, iron studies, and acetaminophen levels were all normal. an abdominal ultrasound showed "fatty liver" and an atrophic pancreas. ct abdomen showed hepatomegaly. |
2021-03-26 |
2023-08-13 |
Not clear |
| Javier Ampuero, Yolanda Sánchez, María Rosario García-Lozano, Douglas Maya-Miles, Manuel Romero Góme. Impact of liver injury on the severity of COVID-19: a systematic review with meta-analysis. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. vol 113. issue 2. 2021-03-25. PMID:33267597. |
we assessed the impact of baseline liver function (aspartate aminotransferase [ast], alanine aminotransferase [alt], bilirubin) on covid-19-related outcomes, including mortality, intensive care unit (icu) admissions, and non-fatal severe complications. |
2021-03-25 |
2023-08-13 |
Not clear |
| Damoon Ashtary-Larky, Reza Bagheri, Matin Ghanavati, Omid Asbaghi, Grant M Tinsley, Delsa Mombaini, Wesam Kooti, Sara Kashkooli, Alexei Won. Effects of betaine supplementation on cardiovascular markers: A systematic review and Meta-analysis. Critical reviews in food science and nutrition. 2021-03-25. PMID:33764214. |
moreover, our analysis indicated that betaine supplementation did not affect serum concentrations of triglyceride (tg), high-density lipoprotein (hdl), fasting blood glucose (fbg), c-reactive protein (crp), liver enzymes [alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transferase (ggt)], and blood pressure. |
2021-03-25 |
2023-08-13 |
Not clear |
| Sedigheh Amiresmaili, Nader Shahrokhi, Mohammad Khaksari, Gholamreza AsadiKaram, Mohammad Reza Aflatoonian, Sara Shirazpour, Ladan Amirkhosravi, Abbas Mortazaeizade. The Hepatoprotective mechanisms of 17β-estradiol after traumatic brain injury in male rats: Classical and non-classical estrogen receptors. Ecotoxicology and environmental safety. vol 213. 2021-03-23. PMID:33582408. |
the results indicated that tbi induces a significant increase in liver enzymes [alkaline phosphatase (alp), aspartate aminotransferase (ast), alanine aminotransferase (alt), glutamyl transferase (ggt)], and oxidants levels [malondialdehyde (mda), nitric oxide (no)] and decreases in antioxidant biomarkers [glutathione peroxidase (gpx) and superoxide dismutase (sod)] in the brain and liver, and plasma. |
2021-03-23 |
2023-08-13 |
rat |
| Yun Huang, Yuyu Zhang, Lili M. Meta-analysis of laboratory results in patients with severe coronavirus disease 2019. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-23. PMID:33747184. |
the results demonstrated that the incidence of leukocytosis, lymphocytopenia, increased procalcitonin (pct), c-reactive protein (crp), aspartate aminotransferase (ast) and lactic dehydrogenase (ldh) levels was associated with a nearly 3-fold (or=3.44; 95% ci: 2.15-5.49), 4-fold (or=4.39; 95% ci: 1.82-10.60), 5-fold (or=5.28; 95% ci: 3.42-8.15), 4-fold (or=3.99; 95% ci: 2.61-6.12), 3-fold (or=3.02; 95% ci: 2.13-4.26) and 8-fold (or=8.33; 95% ci: 1.75-39.69) higher risk of severe covid-19 infection, respectively. |
2021-03-23 |
2023-08-13 |
Not clear |
| Pooya Afaghi, Michael Anthony Lapolla, Khashayar Ghand. Percutaneous microwave ablation applications for liver tumors: recommendations for COVID-19 patients. Heliyon. vol 7. issue 3. 2021-03-23. PMID:33748501. |
as liver injury is also a risk due to covid-19, it is recommended to apply liver function tests to monitor abnormal levels in alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin, and other liver function indicators. |
2021-03-23 |
2023-08-13 |
Not clear |
| Baozeng Chen, Mingjing Feng, Chen Sheng, Yinhua Wang, Wenya Ca. The risk factors for delayed recovery in patients with cardiopulmonary bypass: Why should we care? Medicine. vol 100. issue 11. 2021-03-22. PMID:33725927. |
there were significant differences on the age, aspartate aminotransferase (ast), glutamic pvruvic transaminase (alt), blood urea nitrogen (bun), and serum creatinine (scr) between patients with and without dr (all p < .05); there were no significant differences in the types of surgical procedure (all p > .05); there were significant differences on the duration of cpb, duration of aortic cross clamp (acc), duration of surgery, minimum nasopharyngeal temperature, and transfusion of packed red blood cells between patients with and without dr (all p < .05). |
2021-03-22 |
2023-08-13 |
Not clear |