| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Carlos Hernandez, Da-Wei Yeh, Joel Marh, Hye Yeon Choi, Julia Kim, Shefali Chopra, Li Ding, Matthew Thornton, Brendan Grubbs, Leonard Makowka, Linda Sher, Keigo Machid. Activated and nonactivated MSCs increase survival in humanized mice after acute liver injury through alcohol binging. Hepatology communications. 2022-03-05. PMID:35246968. |
blood samples were obtained at the end of the binge drinking and at the time of death to measure alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels. |
2022-03-05 |
2023-08-13 |
mouse |
| Shuai Wang, Xuemei Fan, Yang Gao, Lijuan Zuo, Mingqi Hong, Yan X. The Relationship Between Zinc Deficiency and Hepatocellular Carcinoma Associated with Hepatitis B Liver Cirrhosis: A 10-year Follow-up Study. Biological trace element research. 2022-03-05. PMID:35247138. |
compared with the non-zinc deficiency group, the zinc deficiency group is older, has a higher proportion of hepatic encephalopathy, higher levels of aspartate aminotransferase(ast), international normalized ratio(inr) and tb, and lower levels of cholinesterase (che), creatinine, and platelet counts (p< 0.05). |
2022-03-05 |
2023-08-13 |
Not clear |
| Pan Ke, Lirong Zhong, Wei Peng, Minzhi Xu, Jie Feng, Qingfeng Tian, Yan He, Rowan Dowling, Wenning Fu, Heng Jiang, Zhiguang Zhao, Kai Lu, Zuxun L. Association of the Serum transaminase with mortality among the United States elderly population. Journal of gastroenterology and hepatology. 2022-03-02. PMID:35233823. |
considering the inconsistent findings of research into the associations between serum levels of liver enzymes (aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyltransferase (ggt)) and mortality among elderly people, we aimed to investigate the associations of alt, ast, ggt and de-ritis ratio (drr, defined as ast/alt) and all-cause or cause-specific mortality among the us elderly people using national health and nutrition examination surveys (nhanes) data. |
2022-03-02 |
2023-08-13 |
Not clear |
| Wenbo Ding, Xiuwei Chen, Licheng Yang, Yaping Chen, Jie Song, Weiquan Bu, Bin Feng, Meng Zhang, Yi Luo, Xiaobin Jia, Liang Fen. Combination of ShuangDan Capsule and Sorafenib Inhibits Tumor Growth and Angiogenesis in Hepatocellular Carcinoma Via PI3K/Akt/mTORC1 Pathway. Integrative cancer therapies. vol 21. 2022-03-02. PMID:35234063. |
sorafenib monotherapy elicited hepatotoxicity for specific expression in the up-regulated level of aspartate transaminase (ast) and ast/glutamic-pyruvic transaminase (alt) ratio, but the co-administration could remedy this adverse effect. |
2022-03-02 |
2023-08-13 |
Not clear |
| Ikponmwosa Ojo, Augustine Apiamu, Egoamaka O Egbune, Nyerhovwo J Tonukar. Biochemical Characterization of Solid-State Fermented Cassava Stem (Manihot esculenta Crantz-MEC) and Its Application in Poultry Feed Formulation. Applied biochemistry and biotechnology. 2022-03-01. PMID:35230606. |
also, examination of alkaline phosphatase (alp) and alanine and aspartate aminotransferases (alt and ast) showed no marked difference in their activities for fermented feed at increasing inoculum sizes when compared with typical poultry feed, respectively (p > 0.05). |
2022-03-01 |
2023-08-13 |
Not clear |
| Ubaid Khan, Rana Uzair Ahmad, Zabeeh Ullah, Tooba Fida, Muhammad Shehrya. Parvovirus b19-Induced Acute Hepatitis With Hepatosplenomegaly and Polyarthropathy. Cureus. vol 14. issue 1. 2022-02-28. PMID:35223271. |
laboratory investigations showed highly elevated aspartate transaminase (ast), alanine transaminase (alt), and bilirubin. |
2022-02-28 |
2023-08-13 |
Not clear |
| Ali Khalifa, Laura Andreias, Sugirdhana Velpar. Adenovirus Hepatitis in Immunocompetent Adults. Journal of investigative medicine high impact case reports. vol 10. 2022-02-28. PMID:35225036. |
laboratory work was normal except for elevated liver function test (lft): alkaline phosphatase (ap) (296), aspartate transaminase (ast) (343), alanine transaminase (alt) (378), and international normalized ratio (inr) (1.23). |
2022-02-28 |
2023-08-13 |
Not clear |
| Sabit Cakmak, Anna Lukina, Subramanian Karthikeyan, Ella Atlas, Robert Dale. The association between blood PFAS concentrations and clinical biochemical measures of organ function and metabolism in participants of the Canadian Health Measures Survey (CHMS). The Science of the total environment. 2022-02-26. PMID:35218824. |
an increase in perfluorooctanoic acid (pfoa) equivalent to the magnitude of its geometric mean (gm) of 2.0 μg/l was associated with percentage (95% ci) increases in serum enzymes reflecting liver function: aspartate aminotransferase (ast) 3.7 (1.1, 6.4), gamma-glutamyl transferase (ggt) 11.8 (2.5, 21.8), alanine aminotransferase (alt) 3.2 (0.5, 5.9), and bilirubin 3.6 (2.7, 4.5). |
2022-02-26 |
2023-08-13 |
human |
| Petr Kelbich, Petr Vachata, Vilem Maly, Tomas Novotny, Jan Spicka, Inka Matuchova, Tomas Radovnicky, Ivan Stanek, Jan Kubalik, Ondrej Karpjuk, Frantisek Smisko, Eva Hanuljakova, Jan Krejse. Neutrophils in Extravascular Body Fluids: Cytological-Energy Analysis Enables Rapid, Reliable and Inexpensive Detection of Purulent Inflammation and Tissue Damage. Life (Basel, Switzerland). vol 12. issue 2. 2022-02-25. PMID:35207447. |
we assessed the relationships between percentages of neutrophils, aerobic and anaerobic metabolism, and tissue damage via the determination of aspartate aminotransferase catalytic activities (ast) in cerebrospinal fluid (csf), pleural effusions (pe), abdominal effusions (ae), and synovial fluids (sf). |
2022-02-25 |
2023-08-13 |
Not clear |
| Han Gyung Kim, Chaeyoung Lee, Ji Hye Yoon, Ji Hye Kim, Jae Youl Ch. BN82002 alleviated tissue damage of septic mice by reducing inflammatory response through inhibiting AKT2/NF-κB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 148. 2022-02-24. PMID:35202908. |
lung edema and serum alanine transaminase (alt), aspartate transaminase (ast), tnf-α, il-1β, and nitric oxide (no) levels also were decreased by bn82002 (20 mg/kg). |
2022-02-24 |
2023-08-13 |
mouse |
| Kai Kang, Yunpeng Luo, Yang Gao, Jiannan Zhang, Changsong Wang, Dongsheng Fei, Wei Yang, Xianglin Meng, Ming Ye, Yan Gao, Haitao Liu, Xue Du, Yuanyuan Ji, Jieling Wei, Wanqiu Xie, Jun Wang, Mingyan Zhao, Kaijiang Y. Continuous Renal Replacement Therapy With oXiris Filter May Not be an Effective Resolution to Alleviate Cytokine Release Syndrome in Non-AKI Patients With Severe and Critical COVID-19. Frontiers in pharmacology. vol 13. 2022-02-21. PMID:35185571. |
clinical data, including the severity of covid-19 white blood cell count (wbc), neutrophil proportion (neut%), lymphocyte count (lymph), lymphocyte percentage (lym%), platelet (plt), c-reaction protein (crp), high sensitivity c-reactive protein (hs-crp), alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tb), albumin (alb), serum creatinine (scr), d-dimer, fibrinogen (fib), il-2, il-4, il-6, il-10, tnf-α, ifn-γ, number of hospital days and sequential organ failure assessment (sofa) score were obtained and collated from medical records, and then compared between the two groups. |
2022-02-21 |
2023-08-13 |
Not clear |
| Ghusoon Al-Janabi, Hayder Neamah Hassan, Ali Al-Fahha. Biochemical changes in patients during hypothyroid phase after thyroidectomy. Journal of medicine and life. vol 15. issue 1. 2022-02-21. PMID:35186143. |
the study also revealed a significant increase in the liver enzymes aspartate aminotransferase (ast) and alanine transaminase (alt) and a significant decrease in alkaline phosphatase (alp) in patients with thyroidectomy compared to the control group. |
2022-02-21 |
2023-08-13 |
human |
| Nour Ibrahim, Jad Hosri, Yara Bteich, Alfred Dib, Antoine Abou Rache. COVID-19 and Liver Dysfunction. Cureus. vol 14. issue 1. 2022-02-21. PMID:35186564. |
results the prevalence of abnormal liver tests among the sample population with severe covid-19 infection were as follows: aspartate aminotransferase (ast), 77%; alanine aminotransferase (alt), 49%; alkaline phosphatase (alp), 12%; and gamma-glutamyl transferase (ggt), 37%. |
2022-02-21 |
2023-08-13 |
Not clear |
| Muhammad Ali Mohsin, Huiru Yu, Rongze He, Peng Wang, Linli Gan, Yulan Du, Yunfei Huang, Muhammad Bakhsh Abro, Sarmad Sohaib, Mariusz Pierzchala, Przemysław Sobiech, Klaudia Miętkiewska, Chandra S Pareek, Bao Xiang H. Differentiation of Subclinical Ketosis and Liver Function Test Indices in Adipose Tissues Associated With Hyperketonemia in Postpartum Dairy Cattle. Frontiers in veterinary science. vol 8. 2022-02-21. PMID:35187139. |
in experiment-2, dynamic monitoring of lft indices namely, alanine aminotransferase (alt), aspartate aminotransferase (ast), γ-glutamyl transpeptidase (ggt), total bilirubin (tbil), direct bilirubin (dbil), total protein (tp), albumin (alb), globulin (glob) and albumin/globulin (a/g) were examined. |
2022-02-21 |
2023-08-13 |
cattle |
| Yue-Hang Jiang, Yue Zhang, Yan-Yan Wang, Wen-Xin Zhang, Meng-Wen Wang, Chao-Qun Liu, Dai-Yin Peng, Nian-Jun Yu, Lei Wang, Wei-Dong Che. [Extracts of Poria cocos polysaccharides improves alcoholic liver disease in mice via CYP2E1 and NF-κB inflammatory pathways]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 1. 2022-02-18. PMID:35178920. |
serum levels of alanine aminotransferase(alt) and aspartate aminotransferase(ast) were detected. |
2022-02-18 |
2023-08-13 |
mouse |
| Zhe Zhang, Yun-Fang Huang, Wen-Wen Zhao, Xiu-Rui Sun, Hong-Cui Han, Xue Wang, Zi-Qi Jing, Peng-Kai Ma, Yu-Jie Zhan. [Effect of Suanzaoren Decoction on molecular levels of bile acids in serum, liver, and ileum of insomnia mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 1. 2022-02-18. PMID:35178923. |
after suanzaoren decoction(48.96 mg·kg~(-1)·d~(-1)) intervention by gavage for 7 days, the related indicators, such as water consumption, food intake, body weight, aspartate aminotransferase(ast), alanine transaminase(alt), and total bile acid(tba) were detected, and the pathological changes of the liver and ileum were observed. |
2022-02-18 |
2023-08-13 |
mouse |
| Man-Ting Hou, Kai-Xin Ding, Ting-Ting He, Yan Yang, Zhao-Fang Bai, Xiao-He Xia. [Meta-analysis of efficacy and safety of Liuwei Wuling Tablets combined with conventional drugs in treatment of liver fibrosis and cirrhosis in chronic hepatitis B]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 1. 2022-02-18. PMID:35178929. |
the meta-analysis results showed that compared with conventional drugs alone, liuwei wuling tablets combined with conventional drugs could increase the effective rate of clinical treatment by reducing serum hyaluronic acid(ha), laminin(ln), procollagen type Ⅲ(pcⅢ), and type Ⅳ collagen(Ⅳ-c) to improve liver function, decreasing the levels of total bilirubin(tbil), alanine amino-transferase(alt), and aspartate aminotransferase(ast), and improving the negative conversion ratio of hepatitis b virus(hbv) dna. |
2022-02-18 |
2023-08-13 |
Not clear |
| Meng-Yao Wang, Gai Gao, Er-Wen Li, Xiao-Wei Zhang, Hui Wang, Jiang-Yan Xu, Zhen-Qiang Zhang, Pan Wang, Zhi-Shen Xi. [Mechanism of Zexie Decoction in improvement of nonalcoholic fatty liver disease based on LKB1/AMPK/PGC-1α pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 2. 2022-02-18. PMID:35178989. |
as revealed by the mtt assay, zxd had no effect on hepg2 activity, but dose-dependently down-regulated alanine aminotransferase(alt) and aspartate aminotransferase(ast) in the liver cell medium induced by pa, and decreased the plasma levels of alt and ast, and total cholesterol(tc) and triglyceride(tg) levels in the liver. |
2022-02-18 |
2023-08-13 |
mouse |
| L V Shevchenko, O M Iakubchak, V A Davydovych, V V Honchar, M Ciorga, J Hartung, R Kołac. Influence of lycopene and astaxanthin in feed on metabolic parameters of laying hens, yolk color of eggs and their content of carotenoids and vitamin A when stored under refrigerated conditions. Polish journal of veterinary sciences. vol 24. issue 4. 2022-02-18. PMID:35179839. |
orientating investigations were carried out in order to test the influence of oil extracts of lycopene (20, 40 and 60 mg/kg feed) and astaxanthin (10, 20 and 30 mg/kg feed) as feed additives on the metabolic parameters (glucose, creatinine, cholesterol) and enzyme activities (alanine aminotransferase, alt; aspartate transaminase, ast) of laying hens. |
2022-02-18 |
2023-08-13 |
Not clear |
| Xin Zhu, Yinhang Zhang, Yingzhuo Zhao, Lijuan Tao, Haiying Liu, Weiguo Dong, Guiqin Yang, Lin L. Effects of dietary supplementation with itaconic acid on the growth performance, nutrient digestibility, slaughter variables, blood biochemical parameters, and intestinal morphology of broiler chickens. Poultry science. vol 101. issue 4. 2022-02-17. PMID:35176702. |
adding ia to the diet had significant effects on superoxide dismutase (sod), alanine aminotransferase (alt), aspartate aminotransferase (ast), and catalase (cat) levels in serum at d 21 and on total antioxidation capacity (t-aoc) at d 42. |
2022-02-17 |
2023-08-13 |
cat |