| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernard Nsengimana, Edozie Samuel Okpara, Wanqing Hou, Chuyun Yan, Shuxin Ha. Involvement of oxidative species in cyclosporine-mediated cholestasis. Frontiers in pharmacology. vol 13. 2022-11-25. PMID:36425570. |
additionally, cyclosporine exerts adverse effects on liver function and redox balance responses in treated rats, as evidenced by its increasing levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and bilirubin while also decreasing the levels of glutathione and nadph. |
2022-11-25 |
2023-08-14 |
rat |
| Flavia Urbano, Mariangela Chiarito, Crescenza Lattanzio, Angela Messa, Marco Ferrante, Mariantonietta Francavilla, Irsida Mehmeti, Giuseppe Lassandro, Paola Giordano, Maria Felicia Faienz. Sex Hormone-Binding Globulin (SHBG) Reduction: The Alarm Bell for the Risk of Non-Alcoholic Fatty Liver Disease in Adolescents with Polycystic Ovary Syndrome. Children (Basel, Switzerland). vol 9. issue 11. 2022-11-24. PMID:36421197. |
thirty-two girls were assessed for anthropometric and biochemical markers: total cholesterol (tc), high density lipoprotein cholesterol (hdl-c), low density lipoprotein cholesterol (ldl-c), triglycerides (tg), glucose, insulin, alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma glutamyl transpeptidase (γgt). |
2022-11-24 |
2023-08-14 |
human |
| Qixin Wang, Yuwen Huang, Yu Li, Luyun Zhang, Huan Tang, Junzhe Zhang, Guangqing Cheng, Minghong Zhao, Tianming Lu, Qian Zhang, Piao Luo, Yinhua Zhu, Fei Xia, Ying Zhang, Dandan Liu, Chen Wang, Haiyan Li, Chong Qiu, Jigang Wang, Qiuyan Gu. Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress. Metabolites. vol 12. issue 11. 2022-11-24. PMID:36422270. |
the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (akp), superoxide dismutase (sod), malondialdehyde (mda), glutathione (gsh), catalase (cat), lactate dehydrogenase (ldh), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β) and interleukin-6 (il-6) were quantified. |
2022-11-24 |
2023-08-14 |
cat |
| Panpan Zhao, Yan Wang, Qiankun Yang, Guili Yu, Fenfen Ma, Jingquan Don. Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell death. Environmental science and pollution research international. 2022-11-23. PMID:36418824. |
abamectin exposure caused cardiac dysfunction by upregulating lactate dehydrogenase (ldh), aspartate aminotransferase (ast), creatine kinase (ck), creatine kinase mb isoenzyme (ck-mb) and white blood cells (wbcs), and decreasing red blood cells (rbcs) and hemoglobin (hb). |
2022-11-23 |
2023-08-14 |
Not clear |
| Luan Manh Chu, Chandima Karunanayake, Palok Aich, Markus Hecker, Punam Pahw. Association between liver enzymes and metabolic syndrome in Canadian adults: results from the Canadian health measures survey - cycles 3 &4. Journal of diabetes and metabolic disorders. vol 21. issue 2. 2022-11-21. PMID:36404860. |
the biomarkers selected were gamma-glutamyl transferase (ggt), aspartate aminotransferase (ast), and alkaline phosphatase (alkp). |
2022-11-21 |
2023-08-14 |
Not clear |
| Anuoluwapo Adelodun, Amro Abdellatief, Oyedotun Babajid. Epstein-Barr Virus Hepatitis Masquerading as Painless Jaundice. Cureus. vol 14. issue 10. 2022-11-21. PMID:36407142. |
she had elevated transaminases: alanine transaminase (alt) of 1287u/l and aspartate aminotransferase of (ast) 1057u/l but her alkaline phosphatase (alp) was only slightly above normal at 109u/l (normal range 35-104u/l), with a direct hyperbilirubinemia - total bilirubin 9.5mg/dl, direct bilirubin 6.8mg/dl; the abdominal ultrasound revealed non-dilated bile ducts. |
2022-11-21 |
2023-08-14 |
Not clear |
| Haijing Zhang, Yifei Yang, Feifei Guo, Rong He, Shuangrong Gao, Chunyu Cao, Chunhui Zhao, Bing Xia, Qihua Xu, Ping Gong, Lifang Wang, Ping Su, Ting Li. Danlu tongdu tablets: Preclinical safety evaluation and mechanism of hepatotoxicity. Frontiers in pharmacology. vol 13. 2022-11-21. PMID:36408216. |
the wide application of danlu tongdu in therapy has raised some clinical adverse reactions, such as significant elevation of alanine transaminase (alt) and aspartate transaminase (ast) in individual patients after use. |
2022-11-21 |
2023-08-14 |
rat |
| Guoxin Xu, Yanping Gong, Fenying Lu, Bin Wang, Zaixing Yang, Long Chen, Jingyu Min, Cuie Cheng, Tingwang Jian. Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis. Scientific reports. vol 12. issue 1. 2022-11-18. PMID:36396948. |
alanine transaminase (alt), alkaline phosphatase (alp), aspartate transaminase (ast), and γ-glutamyltranspetidase (ggt) (4 liver function indexes) serum levels were detected with corresponding activity assay kits. |
2022-11-18 |
2023-08-14 |
mouse |
| Ufuk Yildirim, Fuatcan Balaba. Laboratory markers at admission to predict the presence of totally occluded culprit artery in NSTEMI. Medicine. vol 101. issue 45. 2022-11-18. PMID:36397332. |
neutrophil count [8.13 (2.82-27.88) × 103/µl vs 5.59 (1.85-19.71) × 103/µl, p < .001] and aspartate aminotransferase (ast) level [45 (12-405) u/l vs 25 (5-143) u/l, p < .001] were significantly higher in patients with oca. |
2022-11-18 |
2023-08-14 |
Not clear |
| Ahmed Hamza Al-Shammari, Mohammed Abd Ali Shahadh. The effect of Favipiravir on liver enzyme among patients with mild to moderate COVID-19 infection: A prospective cohort study. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique. vol 29. issue 4. 2022-11-18. PMID:36398597. |
during this period, a baseline assessment of liver enzymes (aspartate aminotransferase - ast, alanine transaminase - alt and alkaline phosphatase - alp) in addition to bilirubin before initiation of therapy and after 1 day of completion of therapy were carried out. |
2022-11-18 |
2023-08-14 |
Not clear |
| Ya-Wen Chen, Chich-Hsiu Hun. Fatigue in Patients with Chronic Hepatitis C. Clinical nursing research. 2022-11-17. PMID:36384333. |
pegylated interferon plus ribavirin dosages and serum values (hemoglobin, alanine aminotransferase [alt], and aspartate aminotransferase [ast]) were monitored before and during the antiviral therapy at 4, 8, 12, 16, 20, and 24 weeks. |
2022-11-17 |
2023-08-14 |
human |
| Jin-Cheng Tian, Hui Liu, Lun-Jie Yan, Zi-Niu Ding, Cheng-Long Han, Bao-Wen Tian, Si-Yu Tan, Zhao-Ru Dong, Dong-Xu Wang, Jun-Shuai Xue, Xin-Cheng Mao, Yu-Chuan Yan, Tao L. Adverse events of immune checkpoint inhibitors in hepatocellular carcinoma: a systemic review and meta-analysis. Clinical and experimental medicine. 2022-11-17. PMID:36385419. |
aspartate aminotransferase (ast) increase (38%, 95% ci 35-40%) is the most common traes. |
2022-11-17 |
2023-08-14 |
Not clear |
| Ting-Li Tang, Yan Yang, Lin Guo, Shuang Xia, Bikui Zhang, Miao Ya. Sunitinib induced hepatotoxicity in L02 cells Frontiers in pharmacology. vol 13. 2022-11-17. PMID:36386201. |
sunitinib significantly reduced the survival of human normal hepatocytes (l02 cells), induced the increase of alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh). |
2022-11-17 |
2023-08-14 |
human |
| Isabella C Hirako, Maísa Mota Antunes, Rafael Machado Rezende, Natália Satchiko Hojo-Souza, Maria Marta Figueiredo, Thomaz Dias, Helder Nakaya, Gustavo Batista Menezes, Ricardo Tostes Gazzinell. Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections. Scientific reports. vol 12. issue 1. 2022-11-17. PMID:36396745. |
similar to patients, infection with plasmodium chabaudi induced acute liver damage as determined by serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) elevation. |
2022-11-17 |
2023-08-14 |
mouse |
| Abhishek Kumar, Ashish Anjanka. A Narrative Review of Vitamin A Supplementation in Preterm and Term Infants. Cureus. vol 14. issue 10. 2022-11-16. PMID:36381685. |
there were no discernible variations in the occurrence of momentarily increased aspartate aminotransferase (ast), alanine transaminase (alt), or alkaline phosphatase between the leading group and the trace group. |
2022-11-16 |
2023-08-14 |
Not clear |
| Ola Nafea, Fatma Ibrahim, Walaa Abdelhami. The reversed De Ritis ratio for predicting in-hospital mortality among intensive care patients with organophosphate poisoning. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2022-11-15. PMID:36377078. |
this study was designed to explore the prognostic role of on-admission hepatic aminotransferases [alanine aminotransferase (alt) and aspartate aminotransferase (ast), and the reversed de ritis ratio (alt/ast)] in the prediction of in-hospital mortality among patients with acute organophosphate (op) poisoning. |
2022-11-15 |
2023-08-14 |
Not clear |
| Hayder Kadhim Jabbar, Meaad Kadhum Hassan, Lamia Mustafa Al-Naam. Lipids profile in children and adolescents with β-thalassemia major. Hematology, transfusion and cell therapy. 2022-11-15. PMID:36379885. |
complete blood count, serum lipids and ferritin, liver function tests, c-reactive protein (crp), high-sensitivity crp (hs-crp) and serum malondialdehyde (mda) were evaluated results: patients with β-tm had significantly lower hemoglobin (hb), total cholesterol (tc), high-density lipoprotein (hdl), low-density lipoprotein (ldl) and non-high-density lipoprotein (non-hdl) and significantly higher very low-density lipoprotein (vldl), triglycerides (tgs), ldl/hdl ratio, mda, hs-crp, total serum bilirubin (tsb), alanine aminotransferase (alt) and aspartate aminotransferase (ast) than the control group (p < 0.05). |
2022-11-15 |
2023-08-14 |
Not clear |
| Yanfei Wei, Jiansheng Cai, Xiaoting Mo, Min Xu, Qiumei Liu, Junling Zhang, Shuzhen Liu, Yinxia Lin, Shenxiang Huang, Jian Qin, Zhiyong Zhan. Associations of Dietary and Plasma Copper Levels with Liver Function in a Chinese Population. Biological trace element research. 2022-11-12. PMID:36369451. |
a cross-sectional study was performed to assess liver function biomarkers-namely, levels of total bilirubin (tbil), direct bilirubin (dbil), indirect bilirubin (ibil), alanine transaminase (alt), and aspartate transaminase (ast)-in 2376 subjects in guangxi, china. |
2022-11-12 |
2023-08-14 |
human |
| Fazul Nabi, Muhammad Asif Arain, Zohaib Ahmed Bhutto, Qurban Ali Shah, Nasrullah Bangulzai, Nisar Ahmed Ujjan, Sarfaraz Ali Fazlan. Effect of early feeding of L-arginine and L-threonine on hatchability and post-hatch performance of broiler chicken. Tropical animal health and production. vol 54. issue 6. 2022-11-12. PMID:36370219. |
the plasma concentration of aspartate aminotransferase (ast) and alanine aminotransferase (alt) were noted to decrease in arg + thr group. |
2022-11-12 |
2023-08-14 |
chicken |
| Gjin Ndrepepa, Stefan Holdenrieder, Adnan Kastrat. Prognostic Value of De Ritis Ratio with Aspartate Aminotransferase and Alanine Aminotransferase Within the Reference Range. Clinica chimica acta; international journal of clinical chemistry. 2022-11-12. PMID:36370837. |
whether aspartate aminotransferase (ast) to alanine aminotransferase (alt ratio (de ritis ratio) with ast and alt activities within the reference range has prognostic value is unknown. |
2022-11-12 |
2023-08-14 |
Not clear |