| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Siwen Li, Jiaqi Xie, Yiang Bai, Zhihao Jiang, Keman Li, Chunling W. Synthetic phenolic antioxidants evoked hepatoxicity in grass carp (Ctenopharyngodon idella) through modulating the ROS-PI3K/mTOR/AKT pathway: Apoptosis-autophagy crosstalk. Fish & shellfish immunology. 2023-06-22. PMID:37348686. |
we observed that bha and bht exposure significantly increased the levels of serum aminotransferase (alt) and aspartate aminotransferase (ast) in grass carp, accompanied by mild inflammatory cell infiltration and irregularity in the shape of hepatocytes. |
2023-06-22 |
2023-08-14 |
cat |
| Muxue Gong, Li Dai, Zhuobei Xie, Dengxiao Hong, Ning Li, Xiaoyun Fan, Changhao Xi. Serological and clinical associations of autoantibodies in Chinese patients with new-onset systemic lupus erythematosus. Scientific reports. vol 13. issue 1. 2023-06-21. PMID:37344560. |
patients with anti-ssb (43.95 ± 73.12 vs. 40.92 ± 75.75, p = 0.004; 63.93 ± 103.56 vs. 55.06 ± 120.84, p = 0.008 respectively) antibodies had higher levels of alanine aminotransferase (alt) and aspartate transaminase (ast), whereas those with anti-p antibody (28.90 ± 25.70 vs. 50.08 ± 93.00, p = 0.014; 38.51 ± 48.19 vs. 69.95 ± 142.67, p = 0.047, respectively) had lower levels of them. |
2023-06-21 |
2023-08-14 |
Not clear |
| Wenmiao He, Aihua Gu, Dayong Wan. Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice. The Science of the total environment. 2023-06-19. PMID:37336398. |
biochemical parameters of liver (alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp)) and kidney (urea and creatinine) were all significantly upregulated by repeated injection with 0.4 and 4 mg/kg 6-ppdq. |
2023-06-19 |
2023-08-14 |
mouse |
| Ashraf B Abdel-Naim, Emad H M Hassanein, Lenah S Binmahfouz, Amina M Bagher, Rawan H Hareeri, Mardi M Algandaby, Yousef A J Fadladdin, Lotfi Aleya, Mohamed M Abdel-Dai. Lycopene attenuates chlorpyrifos-induced hepatotoxicity in rats via activation of Nrf2/HO-1 axis. Ecotoxicology and environmental safety. vol 262. 2023-06-17. PMID:37329850. |
lcp offered protection as evidenced by inhibiting the rise in serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and lactate dehydrogenase (ldh) induced by cpf. |
2023-06-17 |
2023-08-14 |
rat |
| Ali Ardekani, Reza Tabrizi, Elham Maleki, Kamran Bagheri Lankarani, Seyed Taghi Heydari, Mehdi Moradinazar, Maryam Akbar. Effects of coenzyme Q10 supplementation on lipid profiles and liver enzymes of nonalcoholic fatty liver disease (NAFLD) patients: A systematic review and meta-analysis of randomized controlled trials. Food science & nutrition. vol 11. issue 6. 2023-06-16. PMID:37324909. |
the analysis of the six included studies indicated an overall non-significant decrease in the lipid profiles (total cholesterol (tc), low-density lipoprotein cholesterol (ldl), high-density lipoprotein cholesterol (hdl), and triglyceride (tg)), and liver enzymes (aspartate transaminase (ast), alanine transaminase (alt), and gamma-glutamyltransferase (ggt)) of nafld patients who received coq10. |
2023-06-16 |
2023-08-14 |
Not clear |
| Mahmoud M Abo Ghanima, Mohamed E Abd El-Hack, Aljohara M Al-Otaibi, Samia Nasr, Najlaa H Almohmadi, Ayman E Taha, Mariusz Jaremko, Nagwa I El-Kasraw. Growth performance, liver and kidney functions, blood hormonal profile, and economic efficiency of broilers fed different levels of threonine supplementation during feed restriction. Poultry science. vol 102. issue 8. 2023-06-15. PMID:37321031. |
also, a significant increase in alanine aminotransferase (alt), aspartate aminotransferase (ast), and urea levels was observed in feed-restricted birds supplemented with 120 and 130% levels of threonine. |
2023-06-15 |
2023-08-14 |
Not clear |
| Masoud Khosravipour, Masoud Ghanbari Kakavandi, Faramarz Gharagozlou, Farshad Nadri, Akbar Barzegar, Khosro Emami, Hossein Valadi Atha. Independent, modified, and interacting effects of long-term noise, extremely low-frequency electromagnetic fields, and shift work exposures on liver enzymes. Environmental pollution (Barking, Essex : 1987). 2023-06-15. PMID:37321317. |
the fasting blood samples were taken to determine liver enzymes (ast, aspartate transaminase; alt, alanine transaminase). |
2023-06-15 |
2023-08-14 |
human |
| R Ahmed Mohammed, Q J Fadhee. Hepatoprotective Effect of Vitamin B12 in Acetaminophen Induce Hepatotoxicity in Male Rats. Archives of Razi Institute. vol 78. issue 1. 2023-06-14. PMID:37312722. |
plasma levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), glutathione (gsh), total antioxidant capacity (tac), caspase3, malondialdehyde (mda), interleukin-6 (il-6), and tumor necrosis factor-alpha (tnf-) were measured in the cardiac blood samples. |
2023-06-14 |
2023-08-14 |
human |
| Sipra Nayak, Samarendra Das, Rajesh Kumar, Ipsita Iswari Das, Aman Kumar Mohanty, Lakshman Sahoo, Gokul Krsihnan, Jitendra Kumar Sundara. Biochemical and histopathological alterations in freshwater fish, Labeo rohita (Hamilton, 1822) upon chronic exposure to a commonly used hopper insecticide, triflumezopyrim. Chemosphere. 2023-06-14. PMID:37315855. |
the liver, kidney, gills, muscle, and brain tissues of the fish were examined for physiological parameters and biochemical parameters such as catalase (cat), superoxide dismutase (sod), lactate dehydrogenase (ldh), malate dehydrogenase (mdh), alanine aminotransaminase (alt), aspartate aminotransaminase (ast), acetylcholinessterase (ache), and hexokinase. |
2023-06-14 |
2023-08-14 |
cat |
| Hussein G Sawie, Yasser A Khadrawy, Mayada M El-Gizawy, Hagar H Mourad, Enayat A Omara, Eman N Hosn. Effect of alpha-lipoic acid and caffeine-loaded chitosan nanoparticles on obesity and its complications in liver and kidney in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2023-06-12. PMID:37306714. |
at the end of the experiment, the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp) and the levels of urea, creatinine, interleukin-1β (il-1β), and tumor necrosis factor-α (tnf-α) were determined in the sera of animals. |
2023-06-12 |
2023-08-14 |
rat |
| Pedro Fernandes Moura, Inês De Albuquerque Monteiro, Filipa S Pinho, Pedro M Neves, Pedro Silveir. Acute Cocaine Intoxication: An Approach to Severe Hepatic and Renal Dysfunctions. Cureus. vol 15. issue 5. 2023-06-08. PMID:37288187. |
the patient had marked hepatic cytolysis with a peak on the third day with alanine aminotransferase (alt) and aspartate aminotransferase (ast): 7941 and 4453 iu/l, respectively with mild coagulopathy and hyperbilirubinemia. |
2023-06-08 |
2023-08-14 |
Not clear |
| Bing-Yin Li, Jun-Ming Wang, Ling-Ling Song, Ya-Qian Duan, Bing-Yu Long, Ling-Yu Qin, Xiao-Hui Wu, Yan-Mei Wang, Ming-Zhu Gon. [Toxicity attenuation processing technology and mechanism of Rhizoma Dioscoreae Bulbiferae stir-fried with Paeoniae Radix Alba decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 9. 2023-06-07. PMID:37282874. |
the results showed that the processed products of rhizoma dioscoreae bulbiferae stir-fried with paeoniae radix alba decoction reduced the content of diosbulbin b and improved the liver injury induced by rhizoma dioscoreae bul-biferae to varying degrees, and the processing technology of a_2b_2c_3 reduced the excessive levels of alanine transaminase(alt) and aspartate transaminase(ast) induced by raw rhizoma dioscoreae bulbiferae by 50.2% and 42.4%, respectively(p<0.01, p<0.01). |
2023-06-07 |
2023-08-14 |
mouse |
| De-Hua Li, Rui-Sheng Wang, Zhen-Ling Zhang, Jian-Guang Zhu, Meng-Mei Sun, Jia Qia. [Difference of lipid-lowering efficacy of "Xinjianqu" before and after fermentation and its mechanism based on LKB1-AMPK pathway and 16S rDNA sequencing technology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 8. 2023-06-07. PMID:37282903. |
the effects of xinjianqu before and after fermentation on total cholesterol(tc), triacylglyceride(tg), high-density lipoprotein cholesterol(hdl-c), low-density lipoprotein cholesterol(ldl-c), alanine aminotransferase(alt), aspartate aminotransferase(ast), blood urea nitrogen(bun), creatinine(cr), motilin(mtl), gastrin(gas), and the na~+-k~+-atpase levels were determined by enzyme-linked immunosorbent assay(elisa). |
2023-06-07 |
2023-08-14 |
rat |
| Guo-Liang Yin, Hong-Yi Liang, Peng-Peng Liang, Ya-Nan Feng, Su-Wen Chen, Xiang-Yi Liu, Wen-Chao Pan, Feng-Xia Zhan. [Effect of diosgenin on mTOR/FASN/HIF-1α/VEGFA expression in rats with non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 7. 2023-06-07. PMID:37282950. |
the levels of triglyceride(tg), total cholesterol(tc), low-density lipoprotein cholesterol(ldl-c), alanine transaminase(alt), and aspartate transaminase(ast) in the serum were detected by the biochemical method. |
2023-06-07 |
2023-08-14 |
rat |
| Milan Holeče. Roles of malate and aspartate in gluconeogenesis in various physiological and pathological states. Metabolism: clinical and experimental. 2023-06-07. PMID:37286128. |
alternatively, aspartate synthesized from oa by mitochondrial aspartate aminotransferase (ast) is transported to the cytosol in exchange for glutamate via the aspartate-glutamate carrier 2 (agc2). |
2023-06-07 |
2023-08-14 |
Not clear |
| Hongzhu Zhang, Huimin Shi, Shendong Zhou, Guozhen Wei, Wan Xie, Meijuan Meng, Guangjun Chang, Xiangzhen She. Dietary disodium fumarate supplementation alleviates subacute ruminal acidosis (SARA)-induced liver damage by inhibiting pyroptosis Frontiers in immunology. vol 14. 2023-06-06. PMID:37275885. |
using elisa kits and biochemical analyzer, we identified that the contents of interleukin 1beta (il-1β), interleukin 18 (il-18), caspase-1, and the activity of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in hepatic vein were elevated in the hc group. |
2023-06-06 |
2023-08-14 |
Not clear |
| Sallam K Tony, Mohamed Sh Hassan, Hamadi A Ismail, Gamal F Abd El-Naem, Hanaa S S Gazw. Effect of anthocyanin-rich blackberry juice on endoplasmic reticulum stress in streptozotocin-induced diabetic rats. Environmental science and pollution research international. 2023-06-06. PMID:37280499. |
additionally, the levels of blood glucose, total protein, aspartate aminotransferase (ast), albumin, alanine aminotransferase (alt), uric acid, creatinine, and urea improved after the administration of blackberry juice in diabetic rats. |
2023-06-06 |
2023-08-14 |
rat |
| Yuan-Yu Lin, Pei-En Chang, Shih-Yi Shen, Sheng-Der Wan. Effects of indoor and outdoor rearing system on geese biochemical parameters and cecal microbial composition. Poultry science. vol 102. issue 8. 2023-06-05. PMID:37276705. |
our results showed that geese reared in an outdoor system had significantly lower serum aspartate aminotransferase (ast) compared to those reared indoors, but lower levels of high-density lipoprotein (hdl) and higher levels of low-density lipoprotein (ldl). |
2023-06-05 |
2023-08-14 |
Not clear |
| Siwen Li, Jiaqi Xie, Xinlian Li, Qiuyue Li, Xiaoqing Tang, Dongke Yu, Xuan Xion. Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS/Nrf2 and NF-κB signaling in yellow catfish (Pelteobagrus fulvidraco). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-06-03. PMID:37269917. |
at first, yellow catfish (pelteobagrus fulvidraco) exposed to uv-234 (10 μg/l) showed up-regulated serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) and hepatic reactive oxygen species (ros) overproduction, along with significantly reduced activities of antioxidants enzymes and nuclear factor erythroid-derived 2-related factor 2 (nrf2) basal levels. |
2023-06-03 |
2023-08-14 |
Not clear |
| Qi Zheng, Hanzhou Wang, Chao Xue, Shuhan Yang, Yan Wang, Wei Hou, Ying Zhan. A retrospect study based on real-world data to observe metabolic function in cancer patients using albumin-bound paclitaxel. Scientific reports. vol 13. issue 1. 2023-06-03. PMID:37270638. |
the purpose of our study was to determine the levels of serum creatinine (cre), aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), creatine kinase (ck), creatine kinase isoenzyme (ck-mb), white blood cells (wbc) and hemoglobin (hgb) in cancer patients treated with albumin-conjugated paclitaxel. |
2023-06-03 |
2023-08-14 |
Not clear |