| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Göker, E Yurtsever, A Sene. Effect of tenoxicam on biochemical serum parameters of rats. Drug metabolism and drug interactions. vol 15. issue 2-3. 2000-05-04. PMID:10707126. |
the use of tenoxicam has recently increased and it is reported in the literature that treatments lasting between a few weeks to three months caused increases in serum alanine transferase (alt), aspartate transferase (ast), gamma glutamyl transferase (ggt) and bilirubin in humans. |
2000-05-04 |
2023-08-12 |
rat |
| G S Bondy, C L Armstrong, I H Curran, M G Barker, R Meht. Retrospective evaluation of serum ornithine carbamyltransferase activity as an index of hepatotoxicity in toxicological studies with rats. Toxicology letters. vol 114. issue 1-3. 2000-05-01. PMID:10713481. |
changes in serum oct activities were compared with the more widely used clinical endpoints, alanine aminotranserase (alt) and aspartate aminotransferase (ast). |
2000-05-01 |
2023-08-12 |
rat |
| P M López, I T Fiñana, M C De Agueda, E C Sánchez, M C Muñoz, J P Alvarez, E J De La Torre Lozan. Protective effect of melatonin against oxidative stress induced by ligature of extra-hepatic biliary duct in rats: comparison with the effect of S-adenosyl-L-methionine. Journal of pineal research. vol 28. issue 3. 2000-04-25. PMID:10739300. |
the severity of the cholestasis and hepatic injury were determined by the changes in the plasma enzyme activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (ap), g-glutamyl-transpeptidase (ggt), and levels of albumin, total bilirubin (tb) and direct bilirubin (db). |
2000-04-25 |
2023-08-12 |
rat |
| Y L Lin, C C Liu, H Y Lei, T M Yeh, Y S Lin, R M Chen, H S Li. Infection of five human liver cell lines by dengue-2 virus. Journal of medical virology. vol 60. issue 4. 2000-04-20. PMID:10686026. |
moreover, we found that the severity of morphologic aberration and the increase in aspartate aminotransferase (ast) levels correlated with the virus replication rate in the four infected hepatoma cells. |
2000-04-20 |
2023-08-12 |
human |
| N Nakanishi, K Nakamura, K Suzuki, K Tatar. Effects of coffee consumption against the development of liver dysfunction: a 4-year follow-up study of middle-aged Japanese male office workers. Industrial health. vol 38. issue 1. 2000-04-18. PMID:10680318. |
the association of coffee consumption with the development of increased serum aspartate aminotransferase (ast) and/or alanine aminotransferase (alt) activities over 4 years was studied in 1221 liver dysfunction-free (serum ast and alt < or = 39 iu/l and no medical care for or no past history of liver disease) japanese male office workers aged 35 to 56 years. |
2000-04-18 |
2023-08-12 |
Not clear |
| J X Nan, E J Park, H J Kim, G Ko, D H Soh. Antifibrotic effects of the methanol extract of Polygonum aviculare in fibrotic rats induced by bile duct ligation and scission. Biological & pharmaceutical bulletin. vol 23. issue 2. 2000-04-13. PMID:10706393. |
in bdl/s rats, the levels of aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), total bilirubin in serum and hydroxyproline content in liver were dramatically increased. |
2000-04-13 |
2023-08-12 |
rat |
| E Osuna, M D Pérez-Cárceles, M Moreno, A Bedate, J Conejero, J M Abenza, P Martínez, A Lun. Vitreous humor carbohydrate-deficient transferrin concentrations in the postmortem diagnosis of alcoholism. Forensic science international. vol 108. issue 3. 2000-04-13. PMID:10737467. |
in clinical practice biochemical markers, particularly serum gamma-glutamyl-transpeptidase (ggt), alanine aminotransferase (alt), aspartate transaminase (ast), carbohydrate-deficient transferrin (cdt), and erythrocyte mean corpuscular volume are used to diagnose heavy alcohol consumption. |
2000-04-13 |
2023-08-12 |
Not clear |
| B Mohan, A K Patwari, V K Anan. Hepatic dysfunction in childhood dengue infection. Journal of tropical pediatrics. vol 46. issue 1. 2000-04-12. PMID:10730040. |
on admission, levels of serum aspartate transaminase (ast), serum alanine transaminase (alt) and serum alkaline phosphatase (ap) were raised in 80-87 per cent of children with hepatomegaly (group i) and 81 per cent of cases without hepatomegaly (group ii). |
2000-04-12 |
2023-08-12 |
Not clear |
| V Zanardo, L Rizzo, D Trevisanuto, K A Simbi, R Golin, M Magarotto, F Marzar. Serum enzyme activities in premature infants with bronchopulmonary dysplasia. Fetal diagnosis and therapy. vol 14. issue 6. 2000-04-07. PMID:10640872. |
serum alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyltranspeptidase (gamma-gt) and lactate dehydrogenase (ldh) activities were measured in 26 premature infants with bronchopulmonary dysplasia (bpd) (group 1), and in 24 premature controls, matched for gestational age and birth weight (group 2). |
2000-04-07 |
2023-08-12 |
Not clear |
| G Bolger, N Lapeyre, M Rhéaume, P Kibler, C Bousquet, M Garneau, M Cordingle. Acute murine cytomegalovirus infection: a model for determining antiviral activity against CMV induced hepatitis. Antiviral research. vol 44. issue 3. 2000-03-01. PMID:10651067. |
acute intraperitoneal infection of weanling balb/c mice with murine cytomegalovirus (mcmv) resulted in an inoculum titer-dependent weight loss, mortality and elevation of plasma transaminases (alt: alanine transaminase and ast: aspartate transaminase). |
2000-03-01 |
2023-08-12 |
mouse |
| D Tan, Z Xie, M Zhong, Q He, J Li. [Changes of serum myocardial enzymes in patients with malignant hematologic diseases]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. vol 23. issue 5. 2000-03-01. PMID:10682571. |
myocardial enzymes including aspartate aminotransferase (ast), lactate dehydrogenase (ldh), hbd (ldh1 and ldh2), and creatine kinase (ck) and its isoenzyme were monitored in 106 cases of malignant hematologic diseases. |
2000-03-01 |
2023-08-12 |
Not clear |
| Y Iimuro, B U Bradford, S Yamashina, I Rusyn, M Nakagami, N Enomoto, H Kono, W Frey, D Forman, D Brenner, R G Thurma. The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat. Hepatology (Baltimore, Md.). vol 31. issue 2. 2000-02-24. PMID:10655262. |
after 4 weeks, serum aspartate transaminase (ast), necrosis and inflammation were elevated significantly by ethanol compared with appropriate high-fat controls, effects blocked by otc. |
2000-02-24 |
2023-08-12 |
rat |
| J P Fontes, M Gonçalves, V G Ribeir. [Serum markers for ischemic myocardial damage]. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. vol 18. issue 12. 2000-02-24. PMID:10661020. |
assays of serum enzymes, such as aspartate aminotransferase (ast), lactate dehydrogenase (ldh), creatine kinase (ck) and isoenzyme mb, are widely performed in the early phase of suspected ischemic myocardial injury. |
2000-02-24 |
2023-08-12 |
human |
| K Laitinen, T Taub. Clodronate as a cause of aminotransferase elevation. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. vol 10. issue 2. 2000-02-07. PMID:10501791. |
among these groups an elevation above the normal limits occurred in up to 11.7% of the volunteers for aspartate aminotransferase (ast) and up to 17.7% for alt. |
2000-02-07 |
2023-08-12 |
human |
| N Saha, S Dutta, D Häussinge. Changes in free amino acid synthesis in the perfused liver of an air-breathing walking catfish, Clarias batrachus infused with ammonium chloride: a strategy to adapt under hyperammonia stress. The Journal of experimental zoology. vol 286. issue 1. 2000-02-01. PMID:10607365. |
the changes in the free amino acid (faa) levels, the rate of efflux of faas from the perfused liver, and the activity of some enzymes related to amino acid metabolism such as glutamate dehydrogenase (gdh, both reductive amination and oxidative deamination), glutamine synthetase (gs), aspartate aminotransferase (ast), and alanine aminotransferase (alt) were studied in the liver of a freshwater air-breathing teleost, the walking catfish, clarias batrachus, perfused with 5 and 10 mm nh(4)cl. |
2000-02-01 |
2023-08-12 |
Not clear |
| Y Sugimoto, T Tarumi, Y Kaneko, S Isayama, N Kawai, H Sugimoto, H Yamada, C Kame. Effect of propolis extract on D-galactosamine-induced hepatic injury in rats. Biological & pharmaceutical bulletin. vol 22. issue 11. 2000-01-31. PMID:10598035. |
serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities were significantly increased at 24 h after intraperitoneal injection of d-galactosamine (400 mg/kg) in the animals. |
2000-01-31 |
2023-08-12 |
rat |
| K Nosaka, K Sakamot. Changes in plasma enzyme activity after intramuscular injection of bupivacaine into the human biceps brachii. Acta physiologica Scandinavica. vol 167. issue 3. 2000-01-27. PMID:10606828. |
the purpose of this study was to examine the time course of changes in plasma creatine kinase (ck), lactate dehydrogenase (ldh), aspartate (ast) and alanine aminotransferase (alt) activity after intramuscular injection of 0.5% bupivacaine (bpvc). |
2000-01-27 |
2023-08-12 |
human |
| N A Franken, E Strootman, L Hollaar, A van der Laarse, J Wonderge. Myocardial enzyme activities in plasma after whole-heart irradiation in rats. Journal of cancer research and clinical oncology. vol 126. issue 1. 2000-01-27. PMID:10641746. |
therefore, activities of creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), alanine aminotransferase (alt), and alpha-hydroxybutyrate dehydrogenase (alpha-hbdh) were determined in the plasma and left ventricular myocardium of rats following local heart irradiation with a single dose of 20 gy. |
2000-01-27 |
2023-08-12 |
rat |
| M C McDonald, H M Filipe, C Thiemerman. Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock. British journal of pharmacology. vol 128. issue 6. 2000-01-24. PMID:10578150. |
4 haemorrhagic shock resulted in enhanced serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt) and lipase, indicating the development of hepatocellular and pancreatic injury, respectively. |
2000-01-24 |
2023-08-12 |
rat |
| G J Diaz, E J Squires, R J Julia. The use of selected plasma enzyme activities for the diagnosis of fatty liver-hemorrhagic syndrome in laying hens. Avian diseases. vol 43. issue 4. 2000-01-20. PMID:10611993. |
plasma activity of lactate dehydrogenase (ldh), glutamate dehydrogenase (gdh), aspartate aminotransferase (ast), alanine aminotransferase (alt), and creatine kinase (ck) averaged 194 +/- 27, 4.0 +/- 2.8, 146 +/- 20, 1.0 +/- 1.0, and 1041 +/- 268 u/liter, respectively in normal birds. |
2000-01-20 |
2023-08-12 |
Not clear |