| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Mahmoud, S M el-Dafrawy, K A el-Sayed, A T Sharaf el-Di. Effect of Echinostoma liei infection on alterations of protein content and some enzymes in Biomphalaria alexandrina snails. Journal of the Egyptian Society of Parasitology. vol 32. issue 2. 2002-12-12. PMID:12214914. |
a significant elevation in the levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) enzymes was recorded also in exposed snails than unexposed ones (control snails). |
2002-12-12 |
2023-08-12 |
Not clear |
| B W Echard, N A Talpur, A Y Fan, D Bagchi, H G Preus. Hepatoprotective ability of a novel botanical formulation on mild liver injury in rats produced by acute acetaminophen and/or alcohol ingestion. Research communications in molecular pathology and pharmacology. vol 110. issue 1-2. 2002-12-10. PMID:12090358. |
we performed four separate studies using elevations of liver enzymes [aspartate aminotransferase (ast) and alanine aminotransferase (alt)] as our primary biomarkers of hepatotoxicity. |
2002-12-10 |
2023-08-12 |
rat |
| A S El-Khatib, M A Mansou. Prior treatment with captopril attenuates carbon tetrachloride-induced liver injury in mice. Research communications in molecular pathology and pharmacology. vol 110. issue 1-2. 2002-12-10. PMID:12090355. |
twenty-four hours after a single intraperitoneal injection of ccl4 (20 microl/kg), hepatotoxicity was evidenced in the serum by elevated levels of aspartate transaminase (ast; ec: 2.6.1.1), alanine transaminase (alt; ec: 2.6.1.2) and lactate dehydrogenase (ldh; ec: 1.1.1.27) and in the liver by depleted level of reduced glutathione (gsh), enhanced activity of glutathione peroxidase (gsh-px; ec: 1i.11.1.9) and elevated level of lipid peroxides (lp). |
2002-12-10 |
2023-08-12 |
mouse |
| M M Ansar, A Koolooband. Prevalence of hepatitis C virus infection in thalassemia and haemodialysis patients in north Iran-Rasht. Journal of viral hepatitis. vol 9. issue 5. 2002-12-04. PMID:12225335. |
in hcv-positive haemodialysis patients, it was found that there was no correlation with liver function tests (alanine aminotransferase and aspartate aminotransferase: alt and ast), but a significant correlation was observed in respect to the duration of dialysis(p=0.000) and the number of units transfused (p=0.000). |
2002-12-04 |
2023-08-12 |
Not clear |
| Nicole A Stassen, James K Lukan, Eddy H Carrillo, David A Spain, Lisa A Norfleet, Frank B Miller, Hiram C Pol. Examination of the role of abdominal computed tomography in the evaluation of victims of trauma with increased aspartate aminotransferase in the era of focused abdominal sonography for trauma. Surgery. vol 132. issue 4. 2002-12-04. PMID:12407348. |
the purpose of this study was to establish the admission aspartate aminotransferase (ast) level below which patients do not need an abdominal ct for injury evaluation and treatment. |
2002-12-04 |
2023-08-12 |
Not clear |
| Caroline A Sabin, Vince Emery, Helen L Devereux, Anja Griffioen, Jeremy Bishop, Geoff Dusheiko, Thynn Thynn Yee, Esteban Herrero-Martinez, Christine A Le. Long-term patterns of hepatitis C virus RNA concentrations in a cohort of HIV seronegative men with bleeding disorders. Journal of medical virology. vol 68. issue 1. 2002-12-03. PMID:12210432. |
the rna concentration correlated strongly with alanine aminotransferase (alt; correlations of 0.41-0.71 depending on stage of infection) and aspartate aminotransferase (ast; 0.20-0.51) levels. |
2002-12-03 |
2023-08-12 |
Not clear |
| b' Davor Stimac, Sandra Mili\\xc4\\x87, Renata Dobrila Dintinjana, Drazen Kovac, Smiljana Risti\\xc4\\x8. Androgenic/Anabolic steroid-induced toxic hepatitis. Journal of clinical gastroenterology. vol 35. issue 4. 2002-11-26. PMID:12352300.' |
on admission, his bilirubin level was 470 micromol/l (direct, 360 micromol/l), his aspartate aminotransferase (ast) level was 5,870 iu/l, his alanine aminotransferase (alt) level was 10,580 iu/l, his alkaline phosphatase (alp) level was 152 iu/l, his gamma-glutamyl-transpeptidase level was 140 iu/l, his albumin level was 27.6 g/l, and his prothrombin time was 29%. |
2002-11-26 |
2023-08-12 |
Not clear |
| Paul S Giffen, Chris R Pick, Mark A Price, Ann Williams, Malcolm J Yor. Alpha-glutathione S-transferase in the assessment of hepatotoxicity--its diagnostic utility in comparison with other recognized markers in the Wistar Han rat. Toxicologic pathology. vol 30. issue 3. 2002-11-20. PMID:12051554. |
the diagnostic utility of alpha-glutathione s-transferase (alphagst) in the assessment of acute hepatotoxicity was compared with a range of markers including alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2002-11-20 |
2023-08-12 |
rat |
| B Zappacosta, S Persichilli, A Mordente, A Minucci, D Lazzaro, E Meucci, B Giardin. Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione. Human & experimental toxicology. vol 21. issue 1. 2002-11-14. PMID:12046726. |
in this study some salivary enzymes (lactic dehydrogenase [ldh], aspartate aminotransferase [ast] and amylase), and total gsh were measured in 20 volunteers smokers, before and just after smoking a single cigarette. |
2002-11-14 |
2023-08-12 |
human |
| Anders Larsson, Bengt Karlsso. [Modest clinical benefits of ASAT analysis in today's health care. A case report of macro-ASAT giving rise to pathologically increased ASAT levels]. Lakartidningen. vol 99. issue 38. 2002-11-14. PMID:12389251. |
aspartate aminotransferase (ast) may occur as a macroenzyme after forming a complex with immunoglobulins. |
2002-11-14 |
2023-08-12 |
Not clear |
| Yoshihito Takahashi, Raymond W Ganster, Andrea Gambotto, Lifang Shao, Takashi Kaizu, Tong Wu, Gautam P Yagnik, Atsunori Nakao, George Tsoulfas, Takashi Ishikawa, Toyokazu Okuda, David A Geller, Noriko Muras. Role of NF-kappaB on liver cold ischemia-reperfusion injury. American journal of physiology. Gastrointestinal and liver physiology. vol 283. issue 5. 2002-11-13. PMID:12381532. |
in uninfected control livers, nf-kappab was activated biphasically at 1-3 and 12 h after reperfusion with aspartate transaminase (ast) levels of 4,244 +/- 691 iu/l. |
2002-11-13 |
2023-08-12 |
rat |
| A Imaeda, T Kaneko, T Aoki, Y Kondo, N Nakamura, H Nagase, T Yoshikaw. Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 40. issue 10. 2002-11-04. PMID:12387303. |
a single intraperitoneal injection of stz (150 mg/kg) increased serum levels of glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt) and blood urea nitrogen (bun), and also caused dna damage in the liver and kidney. |
2002-11-04 |
2023-08-12 |
mouse |
| H M Levesque, T W Moon, P G C Campbell, A Hontel. Seasonal variation in carbohydrate and lipid metabolism of yellow perch (Perca flavescens) chronically exposed to metals in the field. Aquatic toxicology (Amsterdam, Netherlands). vol 60. issue 3-4. 2002-10-30. PMID:12200090. |
activities of pyruvate kinase (pyk), aspartate transaminase (ast), phosphoenolpyruvate carboxykinase (pepck) and malate dehydrogenase (mdh), were higher in fish from contaminated lakes in fall but not in summer. |
2002-10-30 |
2023-08-12 |
Not clear |
| Ramez Labib, Rita Turkall, Mohamed S Abdel-Rahma. Inhibition of cocaine oxidative metabolism attenuates endotoxin potentiation of cocaine mediated hepatotoxicity. Toxicology. vol 179. issue 1-2. 2002-10-29. PMID:12204538. |
pretreatment with skf-525a reversed the hepatic injury caused by cocaine alone or cocaine and lps treatments, as indicated by both histologic evaluation and serum alanine transaminase (alt) and aspartate transaminase (ast) activities. |
2002-10-29 |
2023-08-12 |
mouse |
| Yen-Hung Yeh, Dar-Yi Wang, Shu-Kong Chen, Jou-Fang Deng, Deng-Fwu Hwan. Effect of chenodeoxycholic acid on the toxicity of 5alpha-cyprinol sulfate in rats. Toxicology. vol 179. issue 1-2. 2002-10-29. PMID:12204539. |
after treated with 5alpha-cyprinol sulfate/chenodeoxycholic acid (9:1), 5alpha-cyprinol sulfate and chenodeoxycholic acid, the relative ratios of liver and kidney weight to body weight, the concentrations of red blood cells (rbc), hemoglobin and hematocrit in the blood, the levels of aspartate transferase (ast), alanine transferase (alt), alkaline phosphatase (alp), blood urea nitrogen (bun) and creatinine in the plasma, and the levels of bun and creatinine in the urine of rats were significantly increased, but body weight of rats and the levels of na(+), k(+), ca(++) in the urine of rats were significantly decreased, especially for both groups of 5alpha-cyprinol sulfate/chenodeoxycholic acid (9:1) and 5alpha-cyprinol sulfate. |
2002-10-29 |
2023-08-12 |
rat |
| Toru Ishidao, Naoki Kunugita, Yukiko Fueta, Keiichi Arashidani, Hajime Hor. Effects of inhaled 1-bromopropane vapor on rat metabolism. Toxicology letters. vol 134. issue 1-3. 2002-10-24. PMID:12191883. |
hepatic cytochromes p450, aspartate aminotransferase (ast) and alanine aminotransferase (alt) in blood decreased significantly with 1-bp exposure, but other enzyme activities did not differ significantly. |
2002-10-24 |
2023-08-12 |
rat |
| Fatma Cağlayan, Osman Cağlayan, Engin Gunel, Yesim Elcuman, Murat Cakma. Intestinal ischemia-reperfusion and plasma enzyme levels. Pediatric surgery international. vol 18. issue 4. 2002-10-18. PMID:12021974. |
plasma aspartate aminotransferase (ast) showed a significant increase during reperfusion while lactate dehydrogenase (ldh) and creatine kinase (ck) levels were significantly increased at the end of ischemia and continued to be so throughout reperfusion. |
2002-10-18 |
2023-08-12 |
Not clear |
| Wen-Hui Fang, Yong-Ming Yao, Zhi-Guo Shi, Yan Yu, Ye Wu, Lian-Rong Lu, Zhi-Yong Shen. The significance of changes in high mobility group-1 protein mRNA expression in rats after thermal injury. Shock (Augusta, Ga.). vol 17. issue 4. 2002-10-10. PMID:11954836. |
in addition, there were high positive correlations between hepatic hmg-1 mrna and serum aminoleucine transferase (alt) and aspartate aminotransferase (ast) levels, and also between pulmonary hmg-1 mrna and myeloperoxidase activities (p < 0.05-0.01). |
2002-10-10 |
2023-08-12 |
mouse |
| Hiroyuki Taniguchi, Eiji Yomota, Koji Nogi, Yuichi Onod. Effects of anti-ulcer agents on ethanol-induced gastric mucosal lesions in D-galactosamine-induced hepatitis rats. Arzneimittel-Forschung. vol 52. issue 8. 2002-10-01. PMID:12236047. |
subcutaneous injection of galn (1 g/kg) remarkably increased serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities suggesting induction of hepatic injury. |
2002-10-01 |
2023-08-12 |
rat |
| Melanie Beaton, Dominique Guyader, Yves Deugnier, Romain Moirand, Subrata Chakrabarti, Paul Adam. Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis. Hepatology (Baltimore, Md.). vol 36. issue 3. 2002-09-27. PMID:12198660. |
ferritin, blood platelets, and aspartate transaminase (ast) level were selected for the clinical index. |
2002-09-27 |
2023-08-12 |
Not clear |