| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter D Jensen, Finn T Jensen, Thorkil Christensen, Johan L Nielsen, Joergen Ellegaar. Relationship between hepatocellular injury and transfusional iron overload prior to and during iron chelation with desferrioxamine: a study in adult patients with acquired anemias. Blood. vol 101. issue 1. 2003-03-18. PMID:12393528. |
we therefore investigated the relationship between the extent of hepatocellular injury as reflected by serum levels of aminotransferases (alanine aminotransferase [alt] and aspartate aminotransferase [ast]) and several iron status indices in 39 anti-hepatitis c virus-negative (hcv(-)) nonthalassemic patients with transfusional iron overload owing to acquired anemias. |
2003-03-18 |
2023-08-12 |
Not clear |
| John Collins, Detlef Ritter, Bruce R Bacon, Michael Landt, Michael H Cree. Macro-aspartate aminotransferase in a female with antibodies to hepatitis C virus. Liver. vol 22. issue 6. 2003-03-18. PMID:12445176. |
persistent elevation of aspartate aminotransferase (ast) activity in serum due to the presence of a macroenzyme form of ast (macro-ast) may lead to diagnostic confusion in many clinical conditions, particularly those associated with chronic liver disease. |
2003-03-18 |
2023-08-12 |
Not clear |
| Theo O Dare, Huw A Davies, John A Turton, Lee Lomas, Thomas C Williams, Malcom J Yor. Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinary parvalbumin-alpha: a biomarker of compound-induced skeletal muscle toxicity in the rat. Electrophoresis. vol 23. issue 18. 2003-03-17. PMID:12298096. |
the skeletal muscle toxicity was monitored using established endpoints such as increase in serum aldolase (aldol), aspartate aminotransferase (ast) and histopathology, and also using seldi retentate chromatography mass spectrometry of urine samples. |
2003-03-17 |
2023-08-12 |
rat |
| Barry Weinberger, Kazimierz Watorek, Richard Strauss, Gisela Witz, Mark Hiatt, Thomas Hegy. Association of lipid peroxidation with hepatocellular injury in preterm infants. Critical care (London, England). vol 6. issue 6. 2003-03-13. PMID:12493074. |
we hypothesized that elevated urinary thiobarbituric-acid-reacting substances (tbars), a marker of oxidative stress, would be associated with hepatocellular injury as measured by serum alanine transaminase (alt) and aspartate transaminase (ast) levels. |
2003-03-13 |
2023-08-12 |
Not clear |
| Ramez Labib, Mohamed S Abdel-Rahman, Rita Turkal. N-acetylcysteine pretreatment decreases cocaine and endotoxin-induced hepatotoxicity. Journal of toxicology and environmental health. Part A. vol 66. issue 3. 2003-03-13. PMID:12521669. |
for the cocaine alone and cocaine and lps groups, nac pretreatment significantly decreased serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities with absence of necrotic hepatic lesions, indicating a reduction of liver injury. |
2003-03-13 |
2023-08-12 |
mouse |
| Hong-min Jian. [Twin test in the determination of alanine aminotransferase and aspartate aminotransferase in the serum]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. vol 27. issue 2. 2003-03-10. PMID:12575344. |
to explore a method which can simultaneously determine alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the serum. |
2003-03-10 |
2023-08-12 |
Not clear |
| Hirokazu Yokoyama, Hiroshi Hirose, Susumu Moriya, Ikuo Sait. Significant correlation between insulin resistance and serum gamma-glutamyl transpeptidase (gamma-GTP) activity in non-drinkers. Alcoholism, clinical and experimental research. vol 26. issue 8 Suppl. 2003-03-07. PMID:12198383. |
the gamma-gtp level was positively correlated with levels of various liver function tests including aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2003-03-07 |
2023-08-12 |
human |
| Nigel W Brown, Marion M Aw, Georgina Mieli-Vergani, Anil Dhawan, J Michael Tredge. Mycophenolic acid and mycophenolic acid glucuronide pharmacokinetics in pediatric liver transplant recipients: effect of cyclosporine and tacrolimus comedication. Therapeutic drug monitoring. vol 24. issue 5. 2003-03-05. PMID:12352931. |
children with elevated aspartate transaminase (ast; but with no evidence of rejection on liver biopsy, n = 7) had significantly lower mpa trough levels compared with those in whom ast was normal (0. |
2003-03-05 |
2023-08-12 |
human |
| J D Tankson, J P Thaxton, Y Vizzier-Thaxto. Biochemical and immunological changes in chickens experiencing pulmonary hypertension syndrome caused by Enterococcus faecalis. Poultry science. vol 81. issue 12. 2003-03-04. PMID:12512573. |
in the present study, serum hemoglobin, glucose, protein, cholesterol, aspartate amino transferase (ast) and creatine kinase-mb (myocardial in origin) enzymes, differential leukocyte numbers, and specific antibody levels against ent. |
2003-03-04 |
2023-08-12 |
Not clear |
| Isabel Villegas, Catalina Alarcón de la Lastra, M José Martín, Virginia Motilva, Carmen La Casa Garcí. Gastric damage induced by subchronic administration of preferential cyclooxygenase-1 and cyclooxygenase-2 inhibitors in rats. Pharmacology. vol 66. issue 2. 2003-03-03. PMID:12207113. |
aspartate aminotransferase (ast or got) increased significantly after 14 days, but after 28 days the values returned to normality. |
2003-03-03 |
2023-08-12 |
rat |
| Jeffrey F Waring, Rebecca Gum, David Morfitt, Robert A Jolly, Rita Ciurlionis, Matthew Heindel, Lori Gallenberg, Bruno Buratto, Roger G Ulric. Identifying toxic mechanisms using DNA microarrays: evidence that an experimental inhibitor of cell adhesion molecule expression signals through the aryl hydrocarbon nuclear receptor. Toxicology. vol 181-182. 2003-02-28. PMID:12505364. |
in a 3-day toxicity study in sprague-dawley rats, a-277249 induced hypertrophy of the liver and elevated serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp). |
2003-02-28 |
2023-08-12 |
rat |
| B J Hargreaves, D S Kronfeld, J N Waldron, M A Lopes, L S Gay, K E Saker, W L Cooper, D J Sklan, P A Harri. Antioxidant status and muscle cell leakage during endurance exercise. Equine veterinary journal. Supplement. issue 34. 2003-02-26. PMID:12405670. |
packed cell volume (pcv), total plasma protein (tpp), plasma ascorbic acid (vit c), plasma alpha-tocopherol (vit e) and erythrocyte glutathione (gsh) concentrations, erythrocyte glutathione peroxidase (gpx), plasma aspartate aminotransferase (ast) and plasma creatine kinase (ck) activities were measured at 0, 40, 80 km and 60 min of recovery (rec) at od80, and 0, 64, 106, 142, 160 km and rec at od160. |
2003-02-26 |
2023-08-12 |
Not clear |
| A Muñoz, C Riber, R Santisteban, R G Lucas, F M Castejó. Effect of training duration and exercise on blood-borne substrates, plasma lactate and enzyme concentrations in Andalusian, Anglo-Arabian and Arabian breeds. Equine veterinary journal. Supplement. issue 34. 2003-02-26. PMID:12405695. |
venous blood samples were collected during the ets and plasma glucose (glu), free fatty acids (ffa), lactate (la), creatine kinase (ck), lactate dehydrogenase (ldh), alpha-hydroxybutyrate dehydrogenase (hbhd), aspartate aminotransferase (ast), na+, k+ and cl- were measured. |
2003-02-26 |
2023-08-12 |
Not clear |
| M Dunnett, R C Harris, C E Dunnett, P A Harri. Plasma carnosine concentration: diurnal variation and effects of age, exercise and muscle damage. Equine veterinary journal. Supplement. issue 34. 2003-02-26. PMID:12405702. |
an apparent relationship was observed between elevated plasma carnosine and increased plasma creatine kinase (ck) and aspartate transaminase (ast) activities. |
2003-02-26 |
2023-08-12 |
Not clear |
| Gamal H El-Sokkary, Hosam M Omar, Abdel-Fattah M M Hassanein, Salvatore Cuzzocrea, Russel J Reite. Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. Free radical biology & medicine. vol 32. issue 4. 2003-02-24. PMID:11841922. |
in the serum, cholesterol levels and liver damage (alkaline phosphatase (alp), aspartate transaminases (ast), total protein, and albumin) were monitored. |
2003-02-24 |
2023-08-12 |
mouse |
| Charles H Halsted, Jesus A Villanueva, Angela M Devli. Folate deficiency, methionine metabolism, and alcoholic liver disease. Alcohol (Fayetteville, N.Y.). vol 27. issue 3. 2003-02-07. PMID:12163145. |
the combined regimen elevated plasma homocysteine, hepatic s-adenosylhomocysteine (sah), urinary 8-hydroxy-2-deoxyguanosine (oxy(8)dg), an index of dna oxidation, and serum aspartate aminotransferase (ast) levels. |
2003-02-07 |
2023-08-12 |
Not clear |
| Charles S Liebe. S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings. Alcohol (Fayetteville, N.Y.). vol 27. issue 3. 2003-02-07. PMID:12163146. |
oral administration of same resulted in its hepatic repletion with a corresponding attenuation of the ethanol-induced oxidative stress and liver injury, with significantly less gsh depletion, less increases in plasma aspartate aminotransferase (ast) levels, less leakage of mitochondrial glutamic dehydrogenase into the plasma, and fewer megamitochondria. |
2003-02-07 |
2023-08-12 |
human |
| A Viveros, A Brenes, I Arija, C Centen. Effects of microbial phytase supplementation on mineral utilization and serum enzyme activities in broiler chicks fed different levels of phosphorus. Poultry science. vol 81. issue 8. 2003-01-24. PMID:12211310. |
by decreasing npp levels in the diet, plasma ca (p < 0.0001), mg (p < 0.0001) and zn (p < 0.0048) concentrations, and alkaline phosphatase (alp) activity (p < 0.0299) increased, and plasma p content (p < 0.0001), aspartate aminotransferase (ast) activity (p < 0.0001), and total protein (tp) content (p < 0.0050) were reduced. |
2003-01-24 |
2023-08-12 |
Not clear |
| Görgün Akpek, John K Boitnott, Linda A Lee, Jason P Hallick, Michael Torbenson, David A Jacobsohn, Sally Arai, Viki Anders, Georgia B Vogelsan. Hepatitic variant of graft-versus-host disease after donor lymphocyte infusion. Blood. vol 100. issue 12. 2003-01-23. PMID:12393729. |
after viral hepatitis and recent drug exposure were excluded, 11 (50%) patients were given a diagnosis of a hepatitic variant of gvhd based on histologic evidence of lobular hepatitis (n = 5), elevation of maximum serum alanine aminotransferase (alt) or aspartate aminotransferase (ast) level more than 10 times the upper normal limit (n = 9), or both. |
2003-01-23 |
2023-08-12 |
Not clear |
| Martin Beránek, Jaroslav Drsata, Vladimír Palick. In vitro glycation of aminotransferases: a process closely depending on the employed experimental conditions. Acta medica (Hradec Kralove). vol 45. issue 3. 2003-01-23. PMID:12515044. |
the aim of the present study is to investigate the influence of various experimental conditions, i.e., two different concentrations of d-fructose as a rapidly glycating substance and three incubation temperatures, on the glycation reaction of alanine aminotransferase (alt, ec 2.6.1.2) and aspartate aminotransferase (ast, ec 2.6.1.1) expressed by decreasing catalytic activities of the enzymes during a 56 day in vitro incubation period. |
2003-01-23 |
2023-08-12 |
Not clear |