Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K H Janbaz, S A Saeed, A H Gilan. Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 11. issue 5. 2004-09-16. PMID:15330498. |
oral administration of sub-lethal dose of paracetamol (640 mg/kg) produced liver damage in rats as manifested by the significant (p<0.01) rise in serum levels of aminotransferases (aspartate transaminase (ast) and alanine transaminase (alt)) compared to respective control values. |
2004-09-16 |
2023-08-12 |
mouse |
R S Devi, Shoba Narayan, K Vijai Mohan, K E Sabitha, C S Shyamala Dev. Effect of a polyherbal formulation, Ambrex, on butylated hydroxy toluene (BHT) induced toxicity in rats. Indian journal of experimental biology. vol 41. issue 11. 2004-09-16. PMID:15332500. |
liver damage was proved by elevated levels of serum protein and markers such as ldh, alp, aspartate amino transferase (ast), alanine amino transferase (alt), decreased level of lipid peroxides (lpo) in serum and glutathione (gsh) in liver. |
2004-09-16 |
2023-08-12 |
rat |
Sarah Donald, Richard D Verschoyle, Peter Greaves, Tina Colombo, Massimo Zucchetti, Cristiano Falcioni, Marco Zaffaroni, Maurizio D'Incalci, Margaret M Manson, Jose Jimeno, William P Steward, Andreas J Gesche. Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma. International journal of cancer. vol 111. issue 6. 2004-09-14. PMID:15300810. |
hepatotoxicity was adjudged by measurement of plasma levels of bilirubin, alkaline phosphatase (alp) and aspartate aminotransferase (ast) and by liver histopathology. |
2004-09-14 |
2023-08-12 |
rat |
Gholamreza Asadi Karam, Mostafa Reisi, Ali Alizadeh Kaseb, Mohammad Khaksari, Abbas Mohammadi, Mehdi Mahmood. Effects of opium addiction on some serum factors in addicts with non-insulin-dependent diabetes mellitus. Addiction biology. vol 9. issue 1. 2004-09-07. PMID:15203439. |
fasting glucose, glycated haemoglobin (hba1c), total cholesterol, high density lipoproteins-cholesterol (hdl-c), triglycerides (tgs), sodium (na(+)), potassium (k(+)), calcium (ca(2+)), iron (fe(2+)), total iron binding capacity (tibc), serum total protein, albumin, alanine aminotransferase (alt), aspartate aminotransferase (ast), uric acid and urea were measured in the serum of the two groups. |
2004-09-07 |
2023-08-12 |
Not clear |
Sezgin Ulukaya, Cigdem Arikan, Sema Aydogdu, Hilmi Omer Ayanoglu, Yaman Toka. Immediate tracheal extubation of pediatric liver transplant recipients in the operating room. Pediatric transplantation. vol 7. issue 5. 2004-09-03. PMID:14738299. |
the aspartate transaminase (ast), alanine transaminase (alt) and protrombin time (pt) were normalized within a week. |
2004-09-03 |
2023-08-12 |
Not clear |
Yasuo Arakawa, Shuichi Amaki, Hiroshi Miyakawa, Toshimitsu Sakai, Iori Gotou, Naohide Tanaka, Mitsuhiko Moriyama, Ariyoshi Iwasaki, Masahiko Sugitani, Yasuyuki Arakaw. PBC-AIH overlap syndrome with concomitant ITP and Hashimoto's disease with positivity for anti-centromere antibody. Journal of gastroenterology. vol 39. issue 5. 2004-08-30. PMID:15175950. |
blood tests revealed: total protein (tp), 6.6 g/dl; gamma-globulin (glb), 35.9%; total bilirubin (t-bil), 9.41 mg/dl; direct bilirubin (d-bil), 7.52 mg/dl; aspartate aminotransferase (ast), 957 u/l; alanine aminotransferase (alt), 651 u/l; alkaline phosphatase (alp), 595 u/l; gamma-guanosine triphosphate (gtp), 129 u/l; igg, 2620 mg/dl; igm, 223 mg/dl; hepatitis b surface antigen (hbsag), negative; anti-hepatitis c virus (hcv), negative; antinuclear antibody, positive; antimitchondrial antibody (ama), negative (by the immunofluorescence [if] method); and anti-pyruvate dehydrogenase complex (pdc)-e2 antibody, positive (by western blotting). |
2004-08-30 |
2023-08-12 |
Not clear |
Jeffrey W-D Foy, Robert A Schat. Inhibition of rat respiratory-tract cytochrome P-450 activity after acute low-level m-xylene inhalation: role in 1-nitronaphthalene toxicity. Inhalation toxicology. vol 16. issue 3. 2004-08-30. PMID:15204773. |
serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were not changed in animals exposed to 1-nn but were increased by m-xylene coexposure. |
2004-08-30 |
2023-08-12 |
rat |
Nimesh S A Patel, Salvatore Cuzzocrea, Prabal K Chatterjee, Rosanna Di Paola, Lidia Sautebin, Domenico Britti, Christoph Thiemerman. Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. Molecular pharmacology. vol 66. issue 2. 2004-08-30. PMID:15266012. |
plasma urea, creatinine, and aspartate aminotransferase (ast) were measured as markers of renal dysfunction and reperfusion injury. |
2004-08-30 |
2023-08-12 |
mouse |
T Sattler, M Fürl. Creatine kinase and aspartate aminotransferase in cows as indicators for endometritis. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 51. issue 3. 2004-08-26. PMID:15214854. |
and aspartate aminotransferase (ast; ec 2.6.1.1.) |
2004-08-26 |
2023-08-12 |
Not clear |
Suresh Chari, Madhur Gupt. Status of blood antioxidant enzymes in alcoholic cirrhosis. Indian journal of physiology and pharmacology. vol 47. issue 3. 2004-08-25. PMID:14723322. |
it was observed that the parameters of liver function like total bilirubin, alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), gamma glutamyl transfarase (gammagt) were increased in cirrhotic (alcoholic or non alcoholic) patients as compared to normal controls. |
2004-08-25 |
2023-08-12 |
human |
Rocco Orlando, Aniello Carbone, Flavio Liruss. Macro-aspartate aminotransferase (macro-AST). A 12-year follow-up study in a young female. European journal of gastroenterology & hepatology. vol 15. issue 12. 2004-08-24. PMID:14624163. |
we describe a case of chronic elevation of serum aspartate aminotransferase (ast) activity due to the presence of a macro-enzyme form of ast (macro-ast) in a young female followed up for 12 years. |
2004-08-24 |
2023-08-12 |
Not clear |
U Jayasree, A Gopala Reddy, K S Reddy, Y Anjaneyulu, B Kalakuma. Evaluation of vitamin E against deltamethrin toxicity in broiler chicks. Indian journal of physiology and pharmacology. vol 47. issue 4. 2004-08-20. PMID:15266958. |
weekly body weights, feed conversion ratio, glutathione (gsh) concentration and high density lipoproteins (hdl) were significantly (p < 0.05) reduced, while the activities of glutathione peroxidase (gsh-px), glutathione reductase (gsh-r), catalase, aspartate aminotransferase (ast) and lactate dehydrogenase (ldh), and the lipid profile and renal biomarkers were increased significantly (p < 0.05) in group 2 and 3 at the end of 4th wk as compared to group 1. |
2004-08-20 |
2023-08-12 |
Not clear |
Miwako Dakeishi, Toyoto Iwata, Noriko Ishii, Katsuyuki Murat. Effects of alcohol consumption on hepatocellular injury in Japanese men. The Tohoku journal of experimental medicine. vol 202. issue 1. 2004-08-19. PMID:14738322. |
to clarify the effects of alcohol consumption on hepatocellular injury, we examined aspartate and alanine aminotransferases (ast and alt), and gamma-glutamyltransferase (ggt), together with weekly alcohol consumption calculated from a self-rating questionnaire, in 1113 japanese salesmen. |
2004-08-19 |
2023-08-12 |
Not clear |
N H El-Sayed, A S Awaad, T J Mabr. Phytochemical studies and effect on urine volume of Glossostemon bruguieri Desf. constituents. Indian journal of experimental biology. vol 42. issue 2. 2004-08-19. PMID:15282952. |
the rat sera were collected and used to determine liver and kidney functions based on alanine amino transferase (alt) and aspartate amino transferase (ast) for both single and repeated administration. |
2004-08-19 |
2023-08-12 |
mouse |
C A Williams, D S Kronfeldt, T M Hess, K E Saker, J N Waldron, K M Crandell, R M Hoffman, P A Harri. Antioxidant supplementation and subsequent oxidative stress of horses during an 80-km endurance race. Journal of animal science. vol 82. issue 2. 2004-08-16. PMID:14974559. |
plasma was assayed for lipid hydroperoxides, alpha-tocopherol, total ascorbate, albumin, creatine kinase (ck), and aspartate aminotransferase (ast). |
2004-08-16 |
2023-08-12 |
Not clear |
Ayman M Gamal el-din, Adel M Mostafa, Othman A Al-Shabanah, Abdullah M Al-Bekairi, Mahmoud N Nag. Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice. Pharmacological research. vol 48. issue 6. 2004-08-12. PMID:14527829. |
arabic gum administration dramatically reduced acetaminophen-induced hepatotoxicity as evidenced by reduced serum alanine (alt) and aspartate aminotransferase (ast) activities. |
2004-08-12 |
2023-08-12 |
mouse |
Takahiro Uenishi, Shoji Kubo, Takatsugu Yamamoto, Taichi Shuto, Masao Ogawa, Hiromu Tanaka, Shogo Tanaka, Kenji Kaneda, Kazuhiro Hirohash. Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence. Cancer science. vol 94. issue 10. 2004-08-06. PMID:14556657. |
log-rank test revealed that ck7 expression, ck19 expression, high aspartate aminotransferase (ast) activity, low albumin concentration, portal invasion, intrahepatic metastasis, and severe fibrosis (cirrhosis) reduced the tumor-free survival rate. |
2004-08-06 |
2023-08-12 |
Not clear |
M A Khasina, S A Dvinskaia, S I Beloglazova, M Iu Khasina, T F Puchinskai. [Vapor condensate of exhaled air in evaluating the impaired metabolism of the bronchopulmanory system in nonspecific lung diseases]. Klinicheskaia laboratornaia diagnostika. issue 5. 2004-08-06. PMID:15230110. |
enzymes alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase, alkaline phosphatase (ap), gamma-glutamate amino-transpeptidase (ggt) as well as parameters of protein metabolism--common protein, seromucoid (sc), c-reactive protein and urea. |
2004-08-06 |
2023-08-12 |
Not clear |
Moritz von Frankenberg, Markus Golling, Arianeb Mehrabi, Hagen Nentwich, Ernst Klar, Thomas W Krau. Donor pretreatment with gadolinium chloride improves early graft function and survival after porcine liver transplantation. Transplant international : official journal of the European Society for Organ Transplantation. vol 16. issue 11. 2004-07-27. PMID:12879229. |
at 1 and 24 h after ltx, the perfusion values were re-evaluated and histology, biochemical (aspartate aminotransferase, ast) and functional parameters (partial thromboplastin time, prothrombin time, and bilirubin) were analyzed. |
2004-07-27 |
2023-08-12 |
rat |
Takayuki Masaki, Seiichi Chiba, Hiroshi Tatsukawa, Tohru Yasuda, Hitoshi Noguchi, Masataka Seike, Hironobu Yoshimats. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology (Baltimore, Md.). vol 40. issue 1. 2004-07-27. PMID:15239101. |
galn/lps treatment induced significant increases in aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in the blood, apoptotic and necrotic changes in hepatocytes, and/or showed a high degree of lethality. |
2004-07-27 |
2023-08-12 |
mouse |