| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanan H Haga. The protective effect of taurine against cyclosporine A-induced oxidative stress and hepatotoxicity in rats. Toxicology letters. vol 151. issue 2. 2004-07-20. PMID:15183458. |
hepatotoxicity was assessed by reduced serum total protein level and increased serum levels of gamma glutamyl transferase (ggt), alanine aminotransferase (alt), and aspartate aminotransaminase (ast). |
2004-07-20 |
2023-08-12 |
rat |
| V V Zinchuk, M N Khodosovsky, D A Maslako. Influence of different oxygen modes on the blood oxygen transport and prooxidant-antioxidant status during hepatic ischemia/reperfusion. Physiological research. vol 52. issue 5. 2004-07-14. PMID:14535828. |
the severity of reperfusion damage was evaluated by the activities of alanine and aspartate aminotransferases (alt, ast) in the blood. |
2004-07-14 |
2023-08-12 |
Not clear |
| J Ziolkowski, L Paczek, M Niewczas, G Senatorski, U Oldakowska-Jedynak, J Wyzgal, B Foroncewicz, K Mucha, J Zegarska, P Nyckowski, K Zieniewicz, W Patkowski, M Krawczyk, B Ziarkiewicz-Wroblewska, B Gornick. Acute liver transplant rejection: incidence and the role of high-doses steroids. Transplantation proceedings. vol 35. issue 6. 2004-07-08. PMID:14529918. |
the only biochemical parameter that was significantly lower in the non-ar group was the aspartate aminotransferase (ast). |
2004-07-08 |
2023-08-12 |
human |
| Theodore A G Smith, Neeraja Idamakanti, Jennifer Marshall-Neff, Michele L Rollence, Patrick Wright, Michele Kaloss, Laura King, Christine Mech, Lisa Dinges, William O Iverson, Alfred D Sherer, Judit E Markovits, Russette M Lyons, Michael Kaleko, Susan C Stevenso. Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates. Human gene therapy. vol 14. issue 17. 2004-07-02. PMID:14633402. |
the ability to detarget the liver corresponded with decreased elevations in liver serum enzymes (aspartate transferase [ast] and alanine transferase [alt]) 24 hr after vector administration and also in serum interleukin (il)-6 levels 6 hr after vector administration. |
2004-07-02 |
2023-08-12 |
mouse |
| Shing Y Ma, Wing Y Au, Irene O L Ng, Albert K W Lie, Anskar Y H Leung, Raymond Liang, George K K Lau, Yok L Kwon. Hepatitic graft-versus-host disease after hematopoietic stem cell transplantation: clinicopathologic features and prognostic implication. Transplantation. vol 77. issue 8. 2004-06-30. PMID:15114094. |
a hepatitic variant was recently recognized, with more than a 10-fold increase in aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels. |
2004-06-30 |
2023-08-12 |
Not clear |
| Mokhtar I Youse. Aluminium-induced changes in hemato-biochemical parameters, lipid peroxidation and enzyme activities of male rabbits: protective role of ascorbic acid. Toxicology. vol 199. issue 1. 2004-06-29. PMID:15125998. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), acid phosphatase (acp), and phosphorylase activities were significantly decreased in liver and testes due to alcl3 administration. |
2004-06-29 |
2023-08-12 |
rabbit |
| Saburo Yoshioka, Atsuhide Hamada, Tailin Cui, Junko Yokota, Sayaka Yamamoto, Masahiko Kusunose, Mitsuhiko Miyamura, Shojiro Kyotani, Ryou Kaneda, Yasuyuki Tsutsui, Kazuhiro Odani, Ichiro Odani, Yutaka Nishiok. Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect. Biological & pharmaceutical bulletin. vol 26. issue 11. 2004-06-28. PMID:14600400. |
furthermore, when prepared hyperlipemia rabbits were administered deep-sea water (desalinated water, hardness 28, 300, and 1200), there were no significant changes in aspartate aminotransferase (ast), alanine aminotransferase (alt), high density lipoprotein cholesterol (hdl-cho), or triglyceride (tg) levels. |
2004-06-28 |
2023-08-12 |
Not clear |
| Kuppuswamy Raju, Govindaraju Anbuganapathi, Velusamy Gokulakrishnan, Balasubramanian Rajkapoor, Balasundarm Jayakar, Sellamuthu Mania. Effect of dried fruits of Solanum nigrum LINN against CCl4-induced hepatic damage in rats. Biological & pharmaceutical bulletin. vol 26. issue 11. 2004-06-28. PMID:14600413. |
the activity was evaluated using biochemical parameters such as serum aspartate amino transferase (ast), alanine amino transferase (alt), alkaline phosphatase (alp) and total bilirubin. |
2004-06-28 |
2023-08-12 |
rat |
| Ji-Xing Nan, Eun-Jeon Park, Jeong Bum Nam, Yu-Zhe Zhao, Xing Fu Cai, Young Ho Kim, Dong Hwan Sohn, Jung-Joon Le. Effect of Acanthopanax koreanum Nakai (Araliaceae) on D-galactosamine and lipopolysaccharide-induced fulminant hepatitis. Journal of ethnopharmacology. vol 92. issue 1. 2004-06-24. PMID:15099851. |
intraperitoneal pretreatment with the water extract or the ethanol-insoluble component of the water extract markedly reduced the elevated levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and tumor necrosis factor-alpha (tnf-alpha), reduced the histological changes in the liver, and attenuated hepatocyte apoptosis confirmed by the terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling method and dna fragmentation assay. |
2004-06-24 |
2023-08-12 |
mouse |
| Lasantha R Bandara, Mike D Kelly, Edward A Lock, Sandy Kenned. A potential biomarker of kidney damage identified by proteomics: preliminary findings. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. vol 8. issue 3-4. 2004-06-23. PMID:12944177. |
therefore, fah may function in a fashion analogous to the aspartate aminotransferase (ast) and alanine aminotransferase (alt) enzymes that are used to measure liver injury. |
2004-06-23 |
2023-08-12 |
human |
| Murat Yagmurca, Ersin Fadillioglu, Hasan Erdogan, Muharrem Ucar, Sadik Sogut, M Kemal Irma. Erdosteine prevents doxorubicin-induced cardiotoxicity in rats. Pharmacological research. vol 48. issue 4. 2004-06-16. PMID:12902208. |
the protein carbonyl content, the activities of myeloperoxidase, aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and creatine kinase (ck) as well as heart rate and blood pressures were significantly increased in dxr group in comparison with the other groups. |
2004-06-16 |
2023-08-12 |
rat |
| A Topal, N Gül, Y Ilçöl, O S Görgü. Hepatic effects of halothane, isoflurane or sevoflurane anaesthesia in dogs. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 50. issue 10. 2004-06-15. PMID:15157022. |
serum level of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp) and gamma-glutamyltransferase (ggt), lactate dehydrogenase (ldh ggt) activities and bilirubin concentration were measured. |
2004-06-15 |
2023-08-12 |
Not clear |
| Daniela M Mori, Amanda M Baviera, Lizeti Toledo de Oliveira Ramalho, Regina C Vendramini, Iguatemy L Brunetti, Maria T Pepat. Temporal response pattern of biochemical analytes in experimental diabetes. Biotechnology and applied biochemistry. vol 38. issue Pt 2. 2004-06-10. PMID:12826018. |
the activities of the enzymes aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ld), creatine kinase (ck), amylase (ams) and angiotensin converting enzyme (ace) have been used to assess the toxic effects of xenobiotics that have hypoglycaemic action in hepatic, pancreatic, renal and muscle tissue. |
2004-06-10 |
2023-08-12 |
rat |
| Lazaros E Tsalikis, Eleftherios G Kaklamanos, Smaragda Kavadia-Tsatala, Eleni Chasapopoulou, Ifigenia Pidonia-Manik. Association of gingival crevicular fluid and serum intracytoplasmic enzyme levels in periodontally healthy homozygous (major) beta-thalassemia patients. Journal of clinical periodontology. vol 31. issue 5. 2004-06-03. PMID:15086617. |
to assess tissue necrosis in beta-thalassemia major patients, as in other areas of medicine, lactate dehydrogenase (ldh), aspartate aminotransferase (ast) and alanine aminotransferase (alt) have been widely used. |
2004-06-03 |
2023-08-12 |
Not clear |
| Frank Par. Correction of bleeding diathesis without liver toxicity using arenaviral-pseudotyped HIV-1-based vectors in hemophilia A mice. Human gene therapy. vol 14. issue 15. 2004-06-02. PMID:14577928. |
interestingly, similar doses of lcmv-pseudotyped lentiviral vectors resulted in minimal systemic or hepatic injury as measured by plasma alanine transferase (alt), aspartate transferase (ast), and tumor necrosis factor (tnf)-alpha compared to the more commonly used envelope, vsv-g. |
2004-06-02 |
2023-08-12 |
mouse |
| Edward Kowalczyk, Anna Kopff, Paweł Fijałkowski, Maria Kopff, Jan Niedworok, Jan Błaszczyk, Józef Kedziora, Piotr Tyślerowic. Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium. Acta biochimica Polonica. vol 50. issue 2. 2004-06-01. PMID:12833179. |
administering anthocyanins with cadmium chloride resulted in a statistically significant decrease of aspartate aminotransferase (ast) and alanine aminotransferase (alt) activity, concentration of bilirubin and urea in blood serum and decreased cadmium cumulation in liver and kidneys in relation to animals receiving cadmium chloride only. |
2004-06-01 |
2023-08-12 |
human |
| Gennaro Nuzzo, Felice Giuliante, Maria Vellone, Germano De Cosmo, Francesco Ardito, Marino Murazio, Fabrizio D'Acapito, Ivo Giovannin. Pedicle clamping with ischemic preconditioning in liver resection. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 10. issue 2 Suppl 1. 2004-05-27. PMID:14762840. |
in spite of the longer duration of ischemia (p=.001), patients with ip had lower aspartate aminotransferase (ast; p=.03) and alanine aminotransferase (alt; p=not significant) at postoperative day 1, with a similar trend at postoperative day 3. |
2004-05-27 |
2023-08-12 |
Not clear |
| Thiruma V Arumugam, Naomi Arnold, Lavinia M Proctor, Michelle Newman, Robert C Reid, Karl A Hansford, David P Fairlie, Ian A Shiels, Stephen M Taylo. Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British journal of pharmacology. vol 140. issue 1. 2004-05-25. PMID:12967936. |
(2) in an acute model of ischaemia (30 min) and reperfusion (150 min) injury in the absence of inhibitors, there was significant intestinal haemorrhage, oedema and mucosal damage, neutropenia, elevated serum levels of aspartate aminotransferase (ast) and hypotension. |
2004-05-25 |
2023-08-12 |
rat |
| Archana Sud, Jason M Hui, Geoffrey C Farrell, Priyanka Bandara, James G Kench, Carolyn Fung, Rita Lin, Dev Samarasinghe, Christopher Liddle, Geoffrey W McCaughan, Jacob Georg. Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance in a probability index. Hepatology (Baltimore, Md.). vol 39. issue 5. 2004-05-24. PMID:15122752. |
among 18 variables associated with severe fibrosis on univariate analysis, multiple logistic regression analysis identified age, aspartate aminotransferase (ast), total cholesterol level, insulin resistance (by homeostasis model), and past alcohol intake as independent predictors of significant fibrosis. |
2004-05-24 |
2023-08-12 |
human |
| Sanjay B Jadhao, Rong-Ze Yang, Qiang Lin, Hong Hu, Frank A Anania, Alan R Shuldiner, Da-Wei Gong, Sanjay B Jadah. Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver. Hepatology (Baltimore, Md.). vol 39. issue 5. 2004-05-24. PMID:15122758. |
furthermore, in fatty liver, total hepatic alt activity is elevated significantly by 30% whereas aspartate aminotransferase (ast) activity remains unchanged. |
2004-05-24 |
2023-08-12 |
mouse |