| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaojiang Tang, Bingling Que, Xiangrong Song, Senhua Li, Xiaojun Yang, Hailan Wang, Hanlin Huang, Michihiro Kamijima, Tamie Nakajima, Yongcheng Lin, Laiyu L. Characterization of liver injury associated with hypersensitive skin reactions induced by trichloroethylene in the guinea pig maximization test. Journal of occupational health. vol 50. issue 2. 2008-06-05. PMID:18403861. |
in the group of tce 4500 mg/kg (ii), alanine aminotransferase (alt) and aspartate aminotransferase (ast) increased (p<0.01), while total protein and globulin decreased (p<0.05). |
2008-06-05 |
2023-08-12 |
Not clear |
| Jae Kyung Kim, Nak Yun Sung, Periasamy Srinivasan, Jong-il Choi, Sang Kyum Kim, Jung Min Oh, Jae Hoon Kim, Beom Seok Song, Hyun Jin Park, Myung Woo Byun, Ju Woon Le. Effect of gamma irradiated hyaluronic acid on acetaminophen induced acute hepatotoxicity. Chemico-biological interactions. vol 172. issue 2. 2008-06-03. PMID:18237725. |
the degree of acute hepatotoxicity was measured by aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2008-06-03 |
2023-08-12 |
mouse |
| Selda Gezginci-Oktayoglu, Sevim Tunali, Refiye Yanardag, Sehnaz Bolken. Effects of Z-FA.FMK on D-galactosamine/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice : effects of Z-FA.FMK on TNF-alpha-mediated kidney injury. Molecular and cellular biochemistry. vol 309. issue 1-2. 2008-05-30. PMID:18008146. |
results in the group given d-galn/tnf-alpha, the following results were found: severe degenerative morphological changes in the kidney tissue, a significant increase in the number of activated caspase-3-positive tubular epithelial cell, an insignificant increase in the number of proliferating cell nuclear antigen (pcna)-positive tubular epithelial cell, a decrease in the kidney glutathione (gsh) levels, catalase (cat), superoxide dismutase (sod) and glutathione peroxidase (gpx) activities, an increase in the kidney lipid peroxidation (lpo) levels, lactate dehydrogenase (ldh) activity, serum aspartate aminotransferase (ast), and alanine aminotransferase (alt) activities, uric acid and urea levels. |
2008-05-30 |
2023-08-12 |
mouse |
| M Tolulope Olaleye, B T João Roch. Acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 59. issue 5. 2008-05-21. PMID:18054472. |
the alanine aminotransferase (alt), and aspartate aminotransferase (ast) activities were determined in the plasma of mice. |
2008-05-21 |
2023-08-12 |
mouse |
| Alfonso S Gozalo, Alfonso Chavera, Enrique J Montoya, Juan Takano, Richard E Welle. Relationship of creatine kinase, aspartate aminotransferase, lactate dehydrogenase, and proteinuria to cardiomyopathy in the owl monkey (Aotus vociferans). Journal of medical primatology. vol 37 Suppl 1. 2008-05-21. PMID:18269526. |
the purpose of this study was to determine serum reference values for creatine kinase (ck), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) in captive-born and wild-caught owl monkeys to assess their usefulness for diagnosing myocardial disease. |
2008-05-21 |
2023-08-12 |
monkey |
| Jorge R Mera, Beverly Dickson, Mark Feldma. Influence of gender on the ratio of serum aspartate aminotransferase (AST) to alanine aminotransferase (ALT) in patients with and without hyperbilirubinemia. Digestive diseases and sciences. vol 53. issue 3. 2008-05-15. PMID:17717745. |
influence of gender on the ratio of serum aspartate aminotransferase (ast) to alanine aminotransferase (alt) in patients with and without hyperbilirubinemia. |
2008-05-15 |
2023-08-12 |
Not clear |
| Abigail Fraser, Shah Ebrahim, George Davey Smith, Debbie A Lawlo. The associations between birthweight and adult markers of liver damage and function. Paediatric and perinatal epidemiology. vol 22. issue 1. 2008-05-12. PMID:18173779. |
no evidence was found for associations of birthweight with aspartate aminotransferase (ast), total bilirubin and albumin. |
2008-05-12 |
2023-08-12 |
human |
| Kazuki Abe, Tadayuki Ikeda, Kenjiro Wake, Tetsuji Sato, Toshitsugu Sato, Hideo Inou. Glycyrrhizin prevents of lipopolysaccharide/D-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice. The Journal of pharmacy and pharmacology. vol 60. issue 1. 2008-05-12. PMID:18251086. |
levels of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) increased after lps/ galn treatment. |
2008-05-12 |
2023-08-12 |
mouse |
| Yeong-Min Yoo, Jung-Hwan Nam, Min-Young Kim, Jongwon Choi, Hee-Juhn Par. Pectolinarin and Pectolinarigenin of Cirsium setidens Prevent the Hepatic Injury in Rats Caused by D-Galactosamine via an Antioxidant Mechanism. Biological & pharmaceutical bulletin. vol 31. issue 4. 2008-05-12. PMID:18379079. |
hepatoprotective activity was measured by the activity of serum aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), and lactate dehydrogenase (ldh). |
2008-05-12 |
2023-08-12 |
rat |
| Josef Ozer, Marcia Ratner, Martin Shaw, Wendy Bailey, Shelli Schomake. The current state of serum biomarkers of hepatotoxicity. Toxicology. vol 245. issue 3. 2008-05-06. PMID:18291570. |
the published literature suggests that these markers, once examined collectively in a large qualification study, could provide additional information relative to serum alt and aspartate aminotransferase (ast) values. |
2008-05-06 |
2023-08-12 |
rat |
| Zhen-ji Wang, Quan Liu, Ping-ping Li, Chen-hui Zou, Zhu-fang She. Effect of GCP-02, a PPARalpha/gamma dual activator, on glucose and lipid metabolism in insulin-resistant mice. European journal of pharmacology. vol 580. issue 1-2. 2008-05-01. PMID:18048028. |
mice were sacrificed, and body length and weight were measured; intraperitoneal adipose, heart and liver weighed; and plasma alanine aminotransferase (alt) level and aspartate aminotransferase (ast) activity measured. |
2008-05-01 |
2023-08-12 |
mouse |
| Muazzez Oner, Gülüzar Atli, Mustafa Canl. Changes in serum biochemical parameters of freshwater fish Oreochromis niloticus following prolonged metal (Ag, Cd, Cr, Cu, Zn) exposures. Environmental toxicology and chemistry. vol 27. issue 2. 2008-05-01. PMID:18348636. |
activities of alkaline phosphatase (alp), alanine transaminase (alt), and aspartate transaminase (ast) were altered only in cu- and cd-exposed fish. |
2008-05-01 |
2023-08-12 |
Not clear |
| G Forlani, P Di Bonito, E Mannucci, B Capaldo, S Genovese, M Orrasch, L Scaldaferri, P Di Bartolo, P Melandri, A Dei Cas, I Zavaroni, G Marchesin. Prevalence of elevated liver enzymes in Type 2 diabetes mellitus and its association with the metabolic syndrome. Journal of endocrinological investigation. vol 31. issue 2. 2008-04-30. PMID:18362506. |
data of 9621 consecutive type 2 diabetes patients (males, 52.4%; median age, 65 yr) were analyzed, and alanine and aspartate aminotransferase (alt, ast) and gamma-glutamyltransferase (ggt) levels were related to body mass index (bmi), metabolic control and the presence of the metabolic syndrome. |
2008-04-30 |
2023-08-12 |
Not clear |
| Ben-Jian Zhang, Dan Xu, Yu Guo, Jie Ping, Liao-Bin Chen, Hui Wan. Protection by and anti-oxidant mechanism of berberine against rat liver fibrosis induced by multiple hepatotoxic factors. Clinical and experimental pharmacology & physiology. vol 35. issue 3. 2008-04-29. PMID:17973934. |
serum levels of alanine aminotransferase (alt) and serum aspartate aminotransferase (ast), hepatic activity of superoxide dismutase (sod) and hepatic malondialdehyde (mda) and hepatic hydroxyproline (hyp) content were determined. |
2008-04-29 |
2023-08-12 |
rat |
| Cheol Young Choi, Kwang Wook An, Myung In A. Molecular characterization and mRNA expression of glutathione peroxidase and glutathione S-transferase during osmotic stress in olive flounder (Paralichthys olivaceus). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 149. issue 3. 2008-04-25. PMID:18302988. |
also, the levels of na(+) and cl(-) decreased, and aspartate aminotransferase (ast) and alanine aminotransferase (alt) increased during the experimental period. |
2008-04-25 |
2023-08-12 |
Not clear |
| Ismail Celik, Ismail Isi. Determination of chemopreventive role of Foeniculum vulgare and Salvia officinalis infusion on trichloroacetic acid-induced increased serum marker enzymes lipid peroxidation and antioxidative defense systems in rats. Natural product research. vol 22. issue 1. 2008-04-24. PMID:17999340. |
the chemopreventive potential of the plant infusions were evaluated by measuring levels of serum marker enzymes [aspartate aminotransferase (ast), alanin aminotransferase (alt), creatine phosphokinase (cpk), acid phosphatase (acp), alkaline phosphatase (alp) and lactate dehydrogenase (ldh)], antioxidant defense systems [reduced glutathione (gsh), glutathione reductase (gr), superoxide dismutase (sod), glutathione-s-transferase (gst) and catalase (cat)] and lipid peroxidation level (malondialdehyde = mda) in various tissues of rats. |
2008-04-24 |
2023-08-12 |
rat |
| Rohit Loomba, Shih-Jen Hwang, Christopher J O'Donnell, R Curtis Ellison, Ramachandran S Vasan, Ralph B D'Agostino, T Jake Liang, Caroline S Fo. Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study. Gastroenterology. vol 134. issue 4. 2008-04-24. PMID:18395076. |
obesity is an important correlate of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels. |
2008-04-24 |
2023-08-12 |
Not clear |
| S Gopumadhavan, Mohammed Rafiq, M Azeemuddin, S K Mitr. Ameliorative effect of Partysmart in rat model of alcoholic liver disease. Indian journal of experimental biology. vol 46. issue 2. 2008-04-22. PMID:18335812. |
after 8 weeks, parameters such as liver weight, liver function serum markers alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) and lipid peroxidation were studied. |
2008-04-22 |
2023-08-12 |
rat |
| Tetsuya Sano, Shunji Kurotobi, Kouji Matsuzaki, Takehisa Yamamoto, Ichiro Maki, Kazunori Miki, Shigetoyo Kogaki, Junichi Har. Prediction of non-responsiveness to standard high-dose gamma-globulin therapy in patients with acute Kawasaki disease before starting initial treatment. European journal of pediatrics. vol 166. issue 2. 2008-04-17. PMID:16896641. |
univariate analysis of pre-ivig data showed that the neutrophil count and serum levels of c-reactive protein (crp), total bilirubin (tb), aspartate aminotransferase (ast), alanine aminotransferase, and lactate dehydrogenase (ldh) were significantly higher in ivig-non-responsive versus responsive patients. |
2008-04-17 |
2023-08-12 |
human |
| Mitsutoshi Kimura, Tadashi Moro, Hajime Motegi, Hiroyuki Maruyama, Mariko Sekine, Hiroshi Okamoto, Hideo Inoue, Toshitsugu Sato, Masahiko Ogihar. In vivo glycyrrhizin accelerates liver regeneration and rapidly lowers serum transaminase activities in 70% partially hepatectomized rats. European journal of pharmacology. vol 579. issue 1-3. 2008-04-15. PMID:18022618. |
serum activity of liver-related transaminases, such as alanine aminotransferase (alt) and aspartate aminotransferase (ast), elevated rapidly on day 1 and decreased to near pre-operative levels on day 5 after 70% partial hepatectomy in saline-treated control rats. |
2008-04-15 |
2023-08-12 |
rat |