| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y H Hu, C L Lin, Y W Huang, P E Liu, D-F Hwan. Dietary amino acid taurine ameliorates liver injury in chronic hepatitis patients. Amino acids. vol 35. issue 2. 2008-10-09. PMID:17690950. |
the 24 chronic hepatitis patients with 2-5 times over normal activities of alanine aminotransferase (alt) or aspartate aminotransferase (ast) were selected and equally divided into taurine treatment and control groups. |
2008-10-09 |
2023-08-12 |
Not clear |
| Sungho Cha, Minjeong Yoon, Yongjoo Ahn, Miyoung Han, Kyung-Lim Yoo. Risk factors for failure of initial intravenous immunoglobulin treatment in Kawasaki disease. Journal of Korean medical science. vol 23. issue 4. 2008-10-07. PMID:18756064. |
in group b, we found that higher bilirubin, aspartate aminotransferase (ast), polymorphonuclear cells (pmn) (%), and lower platelet values at baseline were independent predictors of persistent or recurrent fever in patients with kd. |
2008-10-07 |
2023-08-12 |
Not clear |
| Doni Hikmat Ramdhan, Michihiro Kamijima, Naoyasu Yamada, Yuki Ito, Yukie Yanagiba, Daichi Nakamura, Ai Okamura, Gaku Ichihara, Toshifumi Aoyama, Frank J Gonzalez, Tamie Nakajim. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1. Toxicology and applied pharmacology. vol 231. issue 3. 2008-10-02. PMID:18565563. |
the mice were exposed by inhalation to 0 (control), 1000, or 2000 ppm of tri for 8 h a day, for 7 days, and tri-hepatotoxicity was assessed by measuring plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities and histopathology. |
2008-10-02 |
2023-08-12 |
mouse |
| Yan-Ling Wu, Dong-Ming Piao, Xue-Hua Han, Ji-Xing Na. Protective effects of salidroside against acetaminophen-induced toxicity in mice. Biological & pharmaceutical bulletin. vol 31. issue 8. 2008-09-30. PMID:18670083. |
mice were sacrificed 12 h after the apap injection to determine aspartate aminotransferase (ast), alanine aminotransferase (alt), and tumor necrosis factor-alpha (tnf-alpha) levels in serum and glutathione (gsh) depletion, malondialdehyde (mda) accumulation, and caspase-3 expression in liver tissues. |
2008-09-30 |
2023-08-12 |
mouse |
| Kei Miyanaga, Takashi Yoshioka, Hiroo Nakagawa, Takashi Kitahara, Hideto To, Nobuhiro Ichikawa, Mikiro Nakashima, Koyo Nishida, Junzo Nakamura, Hitoshi Sasak. Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene expression of polyethylenimine/plasmid DNA polyplex. Biological & pharmaceutical bulletin. vol 31. issue 8. 2008-09-30. PMID:18670093. |
the activities of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) in mice indicated the highest peaks at 12 h after d-galn/lps injection, then the activities of serum alt and ast rapidly decreased. |
2008-09-30 |
2023-08-12 |
mouse |
| Ss Yalçin, A Bilgili, I Onbasilar, G Eraslan, M Ozdemi. Synergistic action of sodium selenite and N-acetylcysteine in acetaminophen-induced liver damage. Human & experimental toxicology. vol 27. issue 5. 2008-09-30. PMID:18715889. |
serum alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh) levels were measured. |
2008-09-30 |
2023-08-12 |
mouse |
| b' Roberta Petlevski, Mirko Hadzija, Milivoj Slijepcevi\\xc4\\x87, Dubravka Jureti\\xc4\\x8. Toxicological assessment of P-9801091 plant mixture extract after chronic administration in CBA/HZg mice--a biochemical and histological study. Collegium antropologicum. vol 32. issue 2. 2008-09-30. PMID:18756913.' |
toxic effect of the p-9801091 plant mixture extract was assessed by the following biochemical parameters: urea, creatinine, aspartate aminotransferase (ast), alanine aminotransferase (alt) and cholesterol. |
2008-09-30 |
2023-08-12 |
mouse |
| N A Botsoglou, I A Taitzoglou, E Botsoglou, S N Lavrentiadou, A N Kokoli, N Roubie. Effect of long-term dietary administration of oregano on the alleviation of carbon tetrachloride-induced oxidative stress in rats. Journal of agricultural and food chemistry. vol 56. issue 15. 2008-09-29. PMID:18605733. |
treatment with ccl 4 of rats from the ccl 4 group caused a significant increase in aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) in serum, whereas it decreased cholesterol and triglyceride content as compared to the control. |
2008-09-29 |
2023-08-12 |
rat |
| Saurabh Jha, John W Calvert, Mark R Duranski, Arun Ramachandran, David J Lefe. Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling. American journal of physiology. Heart and circulatory physiology. vol 295. issue 2. 2008-09-25. PMID:18567706. |
h(2)s attenuated the elevation in serum alanine aminotransferase (alt) by 68.6% and aspartate aminotransferase (ast) by 70.8% compared with vehicle group. |
2008-09-25 |
2023-08-12 |
mouse |
| Meltem Kurus, Mukaddes Esrefoglu, Aysun Bay Karabulut, Gokhan Sogutlu, Mine Kaya, Ali Otl. Oral L-arginine protects against cyclosporine-induced hepatotoxicity in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 60. issue 4-5. 2008-09-23. PMID:18583116. |
at the end of the treatments, animals were killed and hepatic tissues were treated for morphological (hematoxylin and eosin) and biochemical (no and malondialdehyde, mda) analyses, and serum was processed for biochemical (alanine transaminase (alt), aspartate transaminase (ast), bilirubin, alkaline phosphatase (alp) and total protein) study. |
2008-09-23 |
2023-08-12 |
rat |
| Christophe Corpechot, Ludovico Abenavoli, Nabila Rabahi, Yves Chrétien, Tony Andréani, Catherine Johanet, Olivier Chazouillères, Raoul Poupo. Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis. Hepatology (Baltimore, Md.). vol 48. issue 3. 2008-09-23. PMID:18752324. |
the efficiency of several combinations of serum bilirubin, alp, and aspartate aminotransferase (ast) threshold values to predict outcome was assessed after 1 year of treatment in 292 patients with pbc. |
2008-09-23 |
2023-08-12 |
Not clear |
| Adriana Kolesarova, Jaroslav Slamecka, Rastislav Jurcik, Frieda Tataruch, Norbert Lukac, Jaroslav Kovacik, Marcela Capcarova, Miroslav Valent, Peter Massany. Environmental levels of cadmium, lead and mercury in brown hares and their relation to blood metabolic parameters. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. vol 43. issue 6. 2008-09-22. PMID:18393073. |
the average concentrations of biochemical parameters in the blood plasma were as follows: ca 3.16 mmol/l, p 2.19 mmol/l, mg 1.40 mmol/l, na 148.71 mmol/l, k 8.12 mmol/l, glucose 6.56 mmol/l, total proteins 56.49 g/l, urea 5.00 mmol/l, total lipids 1.40 g/l, bilirubin 3.97 micro mol/l, cholesterol 1.53 mmol/l, aspartate aminotransferase (ast) 6.06 micro kat/l and alanine aminotransferase (alt) 1.94 micro kat/l. |
2008-09-22 |
2023-08-12 |
Not clear |
| Hirokazu Kano, Yumi Umeda, Misae Saito, Hideki Senoh, Hisao Ohbayashi, Shigetoshi Aiso, Kazunori Yamazaki, Kasuke Nagano, Shoji Fukushim. Thirteen-week oral toxicity of 1,4-dioxane in rats and mice. The Journal of toxicological sciences. vol 33. issue 2. 2008-09-22. PMID:18544906. |
increases in plasma levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) and a decrease in plasma glucose were noted primarily in the rats and mice dosed 25,000 ppm. |
2008-09-22 |
2023-08-12 |
mouse |
| Yusi Zhou, Chung-Mu Park, Chung-Won Cho, Young-Sun Son. Protective effect of pinitol against D-galactosamine-induced hepatotoxicity in rats fed on a high-fat diet. Bioscience, biotechnology, and biochemistry. vol 72. issue 7. 2008-09-22. PMID:18603811. |
the serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and tumor necrosis factor-alpha (tnf-alpha) levels were significantly increased after an injection with galn (p<0.05), but pinitol supplementation at the level of 0.5% reversed these changes to normal levels. |
2008-09-22 |
2023-08-12 |
rat |
| Petra Thulin, Ingalill Rafter, Kenneth Stockling, Celine Tomkiewicz, Ensio Norjavaara, Martine Aggerbeck, Heike Hellmold, Ewa Ehrenborg, Ulf Andersson, Ian Cotgreave, Björn Glinghamma. PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes. Toxicology and applied pharmacology. vol 231. issue 1. 2008-09-19. PMID:18455211. |
in healthy volunteers treated with azd4619, serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities were elevated without an increase in other markers for liver injury. |
2008-09-19 |
2023-08-12 |
human |
| Flavia Carla Meotti, Vanessa Corralo Borges, Juliano Perottoni, Cristina Wayne Nogueir. Toxicological evaluation of subchronic exposure to diphenyl diselenide in rats. Journal of applied toxicology : JAT. vol 28. issue 5. 2008-09-18. PMID:17975852. |
the subchronic administration of diphenyl diselenide at a dose of 300 micromol kg(-1) significantly increased aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities in plasma. |
2008-09-18 |
2023-08-12 |
rat |
| Vladimir Lesnikov, Nicholas Gorden, Nelson Fausto, Emily Spaulding, Jean Campbell, Howard Shulman, Robert E Fleming, H Joachim Dee. Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2. Apoptosis : an international journal on programmed cell death. vol 13. issue 8. 2008-09-17. PMID:18561026. |
here we show in c57bl6j/129 mice with genetic inactivation of transferrin receptor 2 (tfr2(y245x)), that fas-induced hepatotoxicity (apoptosis; rise in plasma aspartate aminotransferase (ast) levels) was comparable to that in wild-type mice, but was not modified by pretreatment with tf. |
2008-09-17 |
2023-08-12 |
mouse |
| S Fakurazi, I Hairuszah, U Nanthin. Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 46. issue 8. 2008-09-15. PMID:18514995. |
the hepatoprotective activity of mo extract was observed following significant histopathological analysis and reduction of the level of alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) in groups pretreated with mo compared to those treated with apap alone. |
2008-09-15 |
2023-08-12 |
rat |
| Toyin Y Faremi, Stephen M Suru, Michael A Fafunso, Udoka E Obioh. Hepatoprotective potentials of Phyllanthusamarus against ethanol-induced oxidative stress in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 46. issue 8. 2008-09-15. PMID:18524448. |
also, p. amarus significantly increased the activities of hepatic alanine transaminase (alt) and aspartate transaminase (ast) as well as alkaline phosphatase (alp), with a concomitant marked reduction in the plasma activity of the transaminases in the ethanol-challenged rats. |
2008-09-15 |
2023-08-12 |
rat |
| Nobuhiko Taniai, Koho Akimaru, Yosinori Ishikawa, Tomohiro Kanada, Daisuke Kakinuma, Yoshiaki Mizuguchi, Yasuhiro Mamada, Hiroshi Yoshida, Takashi Tajir. Hepatotoxicity caused by both tacrolimus and cyclosporine after living donor liver transplantation. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 75. issue 3. 2008-09-11. PMID:18648179. |
the serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and total bilirubin improved initially, but the alt and ast levels later increased. |
2008-09-11 |
2023-08-12 |
Not clear |