| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Song-Zhi Kong, Ji-Cheng Li, Si-Dong Li, Ming-Neng Liao, Cheng-Peng Li, Pin-Jin Zheng, Min-Hui Guo, Wei-Xiang Tan, Zhao-Hui Zheng, Zhang H. Anti-Aging Effect of Chitosan Oligosaccharide on d-Galactose-Induced Subacute Aging in Mice. Marine drugs. vol 16. issue 6. 2018-10-10. PMID:29794973. |
furthermore, cos not only elevated the diminished levels of serum immunoglobulin g (igg) and igm induced by d-gal, but also significantly inhibited the d-gal-caused upregulation of serum alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), uric acid (ua) and creatinine (crea) levels as compared with those of mice in the model group. |
2018-10-10 |
2023-08-13 |
mouse |
| Yong Zhang, Xiaoming Lei, Wei Li, Xiaoying Ding, Jie Bai, Jin Wang, Gang W. TNIP1 alleviates hepatic ischemia/reperfusion injury via the TLR2-Myd88 pathway. Biochemical and biophysical research communications. vol 501. issue 1. 2018-10-09. PMID:29709475. |
in the normal transgene (ntg) group, serum liver damage markers alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh) and gamma glutamyl transferase (ggt) in i/r mice significantly increased compared to the sham-operated mice. |
2018-10-09 |
2023-08-13 |
mouse |
| Chantel Raghu, Joanne Ekena, John M Cullen, Craig B Webb, Lauren A Trepanie. Evaluation of potential serum biomarkers of hepatic fibrosis and necroinflammatory activity in dogs with liver disease. Journal of veterinary internal medicine. vol 32. issue 3. 2018-10-04. PMID:29485210. |
serum interleukin 6 (il-6), chemokine ligand 2 (ccl2), c-reactive protein (crp), and the ratio of aspartate transaminase to alanine transaminase (ast:alt) have been correlated with fibrosis and necroinflammatory activity in humans with various hepatopathies. |
2018-10-04 |
2023-08-13 |
Not clear |
| Faiza Mejri, Slimen Selmi, Alice Martins, Haifa Benkhoud, Tarek Baati, Hedia Chaabane, Leila Njim, Maria L M Serralheiro, Amélia P Rauter, Karim Hosn. Broad bean (Vicia faba L.) pods: a rich source of bioactive ingredients with antimicrobial, antioxidant, enzyme inhibitory, anti-diabetic and health-promoting properties. Food & function. vol 9. issue 4. 2018-10-03. PMID:29589631. |
in alloxan-induced diabetic mice, the oral administration of a methanol extract (500 mg per kg bw) attenuated the elevated levels of serum alanine aminotransferase (ala), aspartate aminotransferase (ast), and alkaline phosphatase activities, and urea, uric acid, and creatinine. |
2018-10-03 |
2023-08-13 |
mouse |
| Yan-Dan Zhou, Jin-Gang Hou, Wei Liu, Shen Ren, Ying-Ping Wang, Rui Zhang, Chen Chen, Zi Wang, Wei L. 20(R)-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis. International immunopharmacology. vol 59. 2018-10-03. PMID:29621733. |
our findings demonstrated that a single injection of apap (250 mg/kg) increased the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), tumor necrosis factor-α (tnf-α), and interleukin-1β (il-1β); such increases were attenuated by pretreatment of mice with 20(r)-rg3 for seven days. |
2018-10-03 |
2023-08-13 |
mouse |
| Xiaolei Hu, Dongsheng Yu, Langen Zhuang, Mengyun Zhou, Zhaoming Shi, Guoxi Jin, Xiaomei Zhan. Geniposide improves hepatic inflammation in diabetic db/db mice. International immunopharmacology. vol 59. 2018-10-03. PMID:29655055. |
the oral glucose tolerance test was performed, and the levels of insulin, alanine aminotransferase (alt), aspartate aminotransaminase (ast), total cholesterol (tc) and triglyceride (tg) were determined. |
2018-10-03 |
2023-08-13 |
mouse |
| Neslihan Pınar, Mahir Kaplan, Tümay Özgür, Oğuzhan Özca. Ameliorating effects of tempol on methotrexate-induced liver injury in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 102. 2018-10-02. PMID:29604595. |
malondialdehyde (mda), myeloperoxidase (mpo), aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were found to be significantly lower in the mtx + tempol group then in the mtx group; while superoxide dismutase (sod), catalase (cat) and glutathione peroxidase (gpx) levels were found to be higher in the mtx + tempol group than in the mtx group. |
2018-10-02 |
2023-08-13 |
rat |
| Huimin Dong, Changzhi Xu, Wenying Zhou, Yuan Liao, Junyan Cao, Zhaoxia Li, Bo H. The combination of 5 serum markers compared to FibroScan to predict significant liver fibrosis in patients with chronic hepatitis B virus. Clinica chimica acta; international journal of clinical chemistry. vol 483. 2018-10-02. PMID:29709450. |
we evaluated the performance of serum hyaluronan (ha), procollagen type iii n-terminal peptide (piiinp), type iv collagen (ivc), laminin (ln), alanine aminotransferase (alt), and aspartate aminotransferase (ast), compared to transient elastography (fibroscan) in predicting significant liver fibrosis. |
2018-10-02 |
2023-08-13 |
Not clear |
| Bangxing Yu, Wen Wan. Cardioprotective Effects of Morroniside in Rats Following Acute Myocardial Infarction. Inflammation. vol 41. issue 2. 2018-10-01. PMID:29168080. |
biomarkers such as creatine kinase (ck-mb), lactate dehydrogenase (ldh), ɑ-hydroxybutyrate dehydrogenase (ɑ-hbdh), and aspartate aminotransferase (ast) activities in ami rats in the serum were detected with commercial kits [2]. |
2018-10-01 |
2023-08-13 |
rat |
| Tingting Wang, Ruoting Men, Mingxing Hu, Xiaoli Fan, Xiaoxue Yang, Xiaojun Huang, Tinghong Ye, Li Yan. Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 100. 2018-10-01. PMID:29428670. |
pretreatment with popx significantly alleviated cona-induced liver injury by down-regulating the levels of plasma alanine transaminase (alt), aspartate transaminase (ast) and cytokine, including tnf-α, interferon (ifn) -γ and interleukin (il)-6. |
2018-10-01 |
2023-08-13 |
mouse |
| Duane T March, Kimberly Vinette-Herrin, Andrew Peters, Ellen Ariel, David Blyde, Doug Hayward, Les Christidis, Brendan P Kelahe. Hematologic and biochemical characteristics of stranded green sea turtles. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. vol 30. issue 3. 2018-10-01. PMID:29436286. |
elevated levels of aspartate aminotransferase (ast) and heterophils were poor prognostic indicators in animals from tz, but not dmm. |
2018-10-01 |
2023-08-13 |
Not clear |
| Dingchun Li, Wu Li, Yihui Chen, Lihui Liu, Dehong Ma, Hongtu Wang, Lu Zhang, Shenjun Zhao, Qin Pen. Anti-fibrotic role and mechanism of Periplaneta americana extracts in CCl4-induced hepatic fibrosis in rats. Acta biochimica et biophysica Sinica. vol 50. issue 5. 2018-10-01. PMID:29538616. |
in this study, we routinely detected liver functional indices, such as alanine aminotransferase (alt), aspartate transaminase (ast), and albumin (alb). |
2018-10-01 |
2023-08-13 |
rat |
| Elena Larrieta-Carrasco, Yvonne N Flores, Luis R Macías-Kauffer, Paula Ramírez-Palacios, Manuel Quiterio, Eric G Ramírez-Salazar, Paola León-Mimila, Berenice Rivera-Paredez, Guillermo Cabrera-Álvarez, Samuel Canizales-Quinteros, Zuo-Feng Zhang, Tania V López-Pérez, Jorge Salmerón, Rafael Velázquez-Cru. Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population. Experimental and molecular pathology. vol 104. issue 1. 2018-09-28. PMID:29307798. |
individuals carrying 9-12 risk alleles had 65.8% and 48.5% higher alt and aspartate aminotransferase (ast) levels, respectively, than those with 1-4 risk alleles. |
2018-09-28 |
2023-08-13 |
Not clear |
| Hui-yuan Bai, Shan Fen. [Protection effects of schizandrin B against liver injury induced by clozapine in mice]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 52. issue 3. 2018-09-28. PMID:29979701. |
the changes of alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase(alp) and antioxidation indexes superoxide dismutase (sod), malonic dialdehyde (mda), glutathione (gsh)and liver histological evaluation were determined. |
2018-09-28 |
2023-08-13 |
mouse |
| Wipaporn Jarujareet, Kensuke Taira, Hong Kean Oo. Dynamics of liver enzymes in rabbits experimentally infected with Fasciola sp. (Intermediate form from Japan). The Journal of veterinary medical science. vol 80. issue 1. 2018-09-27. PMID:29118312. |
gradual increase of serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) were observed from 3 weeks post-inoculation (wpi) and peaked at 6 wpi, which corresponded well to the period of migration and development of juvenile fluke in the liver parenchyma and the time when the young adult flukes migrated to the bile duct. |
2018-09-27 |
2023-08-13 |
rabbit |
| Liubing Lin, Renye Que, Yanting Shen, Yirong Chen, Ni Yan, Yong L. Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620210. |
injury was assessed by the levels of serum alanine aminotransferase (alt) and aspartate transaminase (ast). |
2018-09-26 |
2023-08-13 |
Not clear |
| Xia Sheng, Hui Che, Qingming Ji, Fan Yang, Jie Lv, Yueqiu Wang, Huimin Xian, Lihong Wan. The Relationship Between Liver Enzymes and Insulin Resistance in Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 50. issue 5. 2018-09-26. PMID:29723898. |
liver enzymes including alanine aminotransferase (alt), aspartate aminotransferase (ast), and γ-glutamyl transferase (ggt) were measured, serum fasting glucose and serum fasting insulin were obtained. |
2018-09-26 |
2023-08-13 |
Not clear |
| Dinithi Champika Peiris, Thamali Dhanushk. Low doses of chlorpyrifos interfere with spermatogenesis of rats through reduction of sex hormones. Environmental science and pollution research international. vol 24. issue 26. 2018-09-25. PMID:28721614. |
organ weights, epididymal sperm parameters, dna integrity, sex hormonal (fhs and lh) levels, and alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transferase (ggt), and creatinine concentrations were determined on day 31. |
2018-09-25 |
2023-08-13 |
human |
| Xin-Min Xu, Xiao-Yang Zhou, Xiang-Yu Li, Jie Guo, Hui-Zhu Wang, Yue Li, Cheng-Cheng Yang, Teng-Hui Liu, Jian-Ping Ca. Increased oxidative damage of RNA in liver injury caused by hepatitis B virus (HBV) infection. Free radical research. vol 52. issue 4. 2018-09-25. PMID:29424259. |
we also analysed the levels of urinary 8-oxo-gsn and 8-oxo-dgsn with clinical data of hbeag, hbsag, and hbv genotype and detected the levels of plasma aspartate aminotransferase, alanine aminotransferase (ast), platelet, alkaline phosphatase, prothrombin time (pt) and hbv dna, and calculated the aspartate amino transferase-to-platelet ratio index (apri) score. |
2018-09-25 |
2023-08-13 |
Not clear |
| Shiqi Bian, Zhijun Zhu, Liying Sun, Lin Wei, Wei Qu, Zhigui Zeng, Ying Li. Normothermic Machine Perfusion versus Cold Storage of Liver in Pig Model: A Meta-Analysis. Annals of transplantation. vol 23. 2018-09-25. PMID:29567935. |
the combined results showed that nmp significantly decreased alanine aminotransferase (alt), aspartate aminotransferase (ast), and hyaluronic acid levels in serum or perfusate, significantly increased bile production, and had a similar 5-7-days survival rate after liver transplantation compared with the cs group. |
2018-09-25 |
2023-08-13 |
Not clear |