| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Varsha Rani, Yeshvandra Verma, Kavita Rana, Suresh Vir Singh Ran. Zinc oxide nanoparticles inhibit dimethylnitrosamine induced liver injury in rat. Chemico-biological interactions. vol 295. 2018-12-12. PMID:29024620. |
it diminishes serum alt (alanine transaminases), ast (aspartate transaminases) and ldh (lactate dehydrogenase) showing improvement in liver function. |
2018-12-12 |
2023-08-13 |
rat |
| M G Helal, S E Ayoub, W F Elkashefand, T M Ibrahi. Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention. Human & experimental toxicology. vol 37. issue 9. 2018-12-11. PMID:29249184. |
the hfd-induced liver injury is determined biochemically by evaluating serum alanine aminotransferase (alt), aspartate aminotransferase (ast), albumin, bilirubin, triglycerides, cholesterol, and high-density lipoprotein-cholesterol and by histopathological examination. |
2018-12-11 |
2023-08-13 |
rat |
| Yohei Nakayama, Miyuki Takei-Obi, Izumi Toyoshima-Matsumura, Mai Tsutamori, Ayako Kato, Chiharu Okano, Masaru Mezawa, Yorimasa Ogat. Clinical usability of aspartate aminotransferase to evaluate the prognosis of periodontal regeneration therapies: prospective, longitudinal study. Odontology. vol 106. issue 3. 2018-12-11. PMID:29256042. |
to evaluate the degree of periodontal tissue destruction, aspartate aminotransferase (ast) levels in the gingival crevicular fluid (gcf) are utilized as a predictor of periodontal therapy. |
2018-12-11 |
2023-08-13 |
Not clear |
| Xiang Wang, Jiao Wan. High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. Biological chemistry. vol 399. issue 4. 2018-12-11. PMID:29261513. |
the serum levels of alanine transaminase (alt), aspartate transaminase (ast), total cholesterol (tch) and triglycerides (tg) were measured. |
2018-12-11 |
2023-08-13 |
mouse |
| Kentigern Thorburn, Crawford Fulton, Charlotte King, Difijah Ramaneswaran, Abdulaziz Alammar, Paul S McNamar. Transaminase levels reflect disease severity in children ventilated for respiratory syncytial virus (RSV) bronchiolitis. Scientific reports. vol 8. issue 1. 2018-12-11. PMID:29379110. |
alanine transaminase (alt) and aspartate transaminase (ast) levels were measured daily. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yasser El-Nahhal, Raed Lubba. Acute and single repeated dose effects of low concentrations of chlorpyrifos, diuron, and their combination on chicken. Environmental science and pollution research international. vol 25. issue 11. 2018-12-11. PMID:29397503. |
the effects were determined as biological response (chicken behavior); physiological response (body weight, gaining weight); and biochemical response such as reduction of acetylcholine esterase activity (ache), changes in liver biomarkers, such as (1) alkaline phosphatase (alp), (2) aspartate aminotransferase (ast), and (3) alanine aminotransferase (alp), and effects on kidney biomarkers such as total protein, creatinine, uric acid, and urea. |
2018-12-11 |
2023-08-13 |
chicken |
| Qudsia Kanwal, Abdul Qadir, Amina, Asmatullah, Hafiza Hira Iqbal, Bushra Muni. Healing potential of Adiantum capillus-veneris L. plant extract on bisphenol A-induced hepatic toxicity in male albino rats. Environmental science and pollution research international. vol 25. issue 12. 2018-12-11. PMID:29446025. |
it was concluded that the bpa can reduce the body and liver weight, increase in biochemical levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), total bilirubin, and disturb the normal hepatic physiology, histology, and metabolism. |
2018-12-11 |
2023-08-13 |
rat |
| K Isoda, T Nozawa, Y Taira, I Taira, Y Shimizu, I Ishid. Effects of surface charge and palladium on hepatic and kidney injury induced by polystyrene nanoparticles co-administered to mice with paraquat and cisplatin. Die Pharmazie. vol 73. issue 3. 2018-12-11. PMID:29544565. |
the results showed that when npp50-nh2, npp50-cooh, or pd-npp50 was administered alone via the mouse tail vein, serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and blood urea nitrogen (bun) did not increase or cause injury. |
2018-12-11 |
2023-08-13 |
mouse |
| Yongxia Yin, Xiaofeng Liu, Jinping Liu, Enbo Cai, Hongyan Zhu, Haijun Li, Lianxue Zhang, Pingya Li, Yan Zha. Beta-sitosterol and its derivatives repress lipopolysaccharide/d-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice. Bioorganic & medicinal chemistry letters. vol 28. issue 9. 2018-12-11. PMID:29622518. |
final experimental results showed that sit-n significantly decreased the serum activity of aspartate transaminase (ast) and alanine aminotransferase (alt); sit-n also markedly reduced tumor necrosis factor (tnf-α), interleukin-1β (il-1β) and interleukin-6 (il-6) levels. |
2018-12-11 |
2023-08-13 |
mouse |
| M E Erdemli, B Yigitcan, M Gul, H G Bag, S Gul, Z Aksungu. Thymoquinone is protective against 2,3,7,8-tetrachlorodibenzo-p-dioxin induced hepatotoxicity. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 93. issue 6. 2018-12-11. PMID:29701106. |
tcdd administration increased malondialdehyde (mda), total oxidant status (tos), alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) levels in rat liver tissue and reduced glutathione (gsh), superoxide dismutase (sod), catalase (cat) and total antioxidant status (tas) levels compared to all other groups. |
2018-12-11 |
2023-08-13 |
rat |
| Johann F Coetzee, Michael D Kleinhenz, Drew R Magstadt, Vickie L Cooper, Larry W Wulf, Nicholas K Van Engen, Joseph S Smith, Nathan Rand, Butch KuKanich, Patrick J Gorde. Pneumatic dart delivery of tulathromycin in calves results in lower antimicrobial concentrations and increased biomarkers of stress and injection site inflammation compared with subcutaneous injection. Journal of animal science. vol 96. issue 8. 2018-12-11. PMID:29873747. |
serum tulathromycin, cortisol, creatine kinase (ck), and aspartate aminotransferase (ast) concentrations were determined in combination with other biomarkers of inflammation including mechanical nociceptive threshold (mnt), infrared thermography (irt), and swelling at the injection site over 432 h after administration. |
2018-12-11 |
2023-08-13 |
cattle |
| Ziyi Li, Fazhang Zhao, Yonggang Cao, Jingyan Zhang, Pilong Shi, Xueying Sun, Feng Zhang, Liquan Ton. DHA attenuates hepatic ischemia reperfusion injury by inhibiting pyroptosis and activating PI3K/Akt pathway. European journal of pharmacology. vol 835. 2018-12-11. PMID:30075219. |
here, we show that dha protected hepatic i/r injury by reducing aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels and decreasing the oxidative stress in liver tissues. |
2018-12-11 |
2023-08-13 |
rat |
| Pankaj G Jain, Umesh B Mahajan, Sachin D Shinde, Sanjay J Suran. Cardioprotective role of FA against isoproterenol induced cardiac toxicity. Molecular biology reports. vol 45. issue 5. 2018-12-11. PMID:30105550. |
subcutaneously for two consecutive days in the experimental group resulted in acute cardiac toxicity as evidenced by changes in electrocardiogram (ecg) pattern and marked elevation of serum cardiac enzymes viz aspartate aminotransferase (ast), alanine transaminase (alt), creatinine kinase (ck-mb) and lactate dehydrogenase (ldh) also increases inflammatory cytokines. |
2018-12-11 |
2023-08-13 |
rat |
| Shulan Li, Juan Liu, Mengya Zhang, Yuan Chen, Tianxing Zhu, Jun Wan. Protective Effect of Eckol against Acute Hepatic Injury Induced by Carbon Tetrachloride in Mice. Marine drugs. vol 16. issue 9. 2018-12-11. PMID:30150561. |
results revealed that eckol pre-treatment at the dose of 0.5 and 1.0 mg/kg/day for 7 days significantly suppressed the ccl₄-induced increases of alanine transaminase (alt) and aspartate aminotransferase (ast) levels in serum and meliorated morphological liver injury. |
2018-12-11 |
2023-08-13 |
mouse |
| Ponmari Guruvaiah, Huimin Guo, Daxiang Li, Zhongwen Xi. Preventive Effect of Flavonol Derivatives Abundant Sanglan Tea on Long-Term High-Fat-Diet-Induced Obesity Complications in C57BL/6 Mice. Nutrients. vol 10. issue 9. 2018-12-11. PMID:30201876. |
a dietary supplement of slt efficiently managed the blood glucose elevation, retained the serum total cholesterol (tc), ldl-cholesterol (ldl-c), and triglyceride (tg) levels, as well as aspartate aminotransferase (ast) and alanine aminotransferase (alt) activity, and reduced the fat storage in the liver induced by a high-fat diet. |
2018-12-11 |
2023-08-13 |
mouse |
| Yanni Pan, Xingyao Long, Ruokun Yi, Xin Zha. Polyphenols in Liubao Tea Can Prevent CCl₄-Induced Hepatic Damage in Mice through Its Antioxidant Capacities. Nutrients. vol 10. issue 9. 2018-12-11. PMID:30201943. |
plt also downregulates aspartate aminotransferase (ast), alanine aminotransferase (alt), triglycerides (tgs), and malondialdehyde (mda), and upregulates superoxide dismutase (sod) and glutathione peroxidase (gsh-px) in the sera of mice with liver injury. |
2018-12-11 |
2023-08-13 |
mouse |
| Milan Radovanovic, Tetyana Dushenkovska, Ivan Cvorovic, Natasa Radovanovic, Vimala Ramasamy, Katarina Milosavljevic, Jelena Surla, Mladen Jecmenica, Miroslav Radulovic, Tamara Milovanovic, Igor Dumi. Idiosyncratic Drug-Induced Liver Injury Due to Ciprofloxacin: A Report of Two Cases and Review of the Literature. The American journal of case reports. vol 19. 2018-12-11. PMID:30266895. |
on the second day of ciprofloxacin treatment, he developed abdominal pain, nausea, vomiting and increased serum levels of liver transaminases, aspartate aminotransferase (ast), and alanine aminotransferase (alt). |
2018-12-11 |
2023-08-13 |
Not clear |
| Adriele Dandara Levorato, Daniela Vanessa Moris, Ricardo de Souza Cavalcante, Tatiane Fernanda Sylvestre, Priscila Zacarias de Azevedo, Lídia Raquel de Carvalho, Rinaldo Poncio Mende. Evaluation of the hepatobiliary system in patients with paracoccidioidomycosis treated with cotrimoxazole or itraconazole. Medical mycology. vol 56. issue 5. 2018-11-27. PMID:29420819. |
serum levels of direct bilirubin (db), total bilirubin (tb), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and gamma-glutamyl transferase (ggt) were evaluated. |
2018-11-27 |
2023-08-13 |
Not clear |
| Bin Li, Dongnan Li, Yuehua Wang, Xianjun Meng, Xiyun Sun, Jinlong Tian, Lin Shi, Fengming M. Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway. Experimental animals. vol 67. issue 4. 2018-11-27. PMID:29806627. |
the activities of aspartate aminotransferase (ast, 61.90 ± 14.65 vs. 93.65 ± 20.50, 50.46 ± 13.21 vs. 93.65 ± 20.50) and alanine transaminase (alt, 41.29 ± 9.20 vs. 64.04 ± 18.13, 36.52 ± 7.71 vs. 64.04 ± 18.13) in the serum of ali mice were significantly reduced by 100 mg/kg or 200 mg/kg sina when compared with control mice. |
2018-11-27 |
2023-08-13 |
mouse |
| Xiao-Di Fan, Hai-Bo Zheng, Xiu-Shuang Fan, Shan L. Increase of SOX9 promotes hepatic ischemia/reperfusion (IR) injury by activating TGF-β1. Biochemical and biophysical research communications. vol 503. issue 1. 2018-11-26. PMID:29879429. |
in the present study, a hepatic ir injury model was established, supported by a significant histological alteration with high suzuki scores, and a remarkable up-regulation of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2018-11-26 |
2023-08-13 |
mouse |