| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tony J Fang, Jiun-Ting Guo, Ming-Kuem Lin, Meng-Shiou Lee, Yen-Lien Chen, Wen-Hsin Li. Protective effects of Lactobacillus plantarum against chronic alcohol-induced liver injury in the murine model. Applied microbiology and biotechnology. vol 103. issue 20. 2020-02-04. PMID:31515596. |
the liver injury was examined by measuring the levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), malondialdehyde (mda), anti-oxidative enzyme, endotoxin, inflammatory cytokines, and lipid accumulation in the liver or serum among different groups. |
2020-02-04 |
2023-08-13 |
mouse |
| Anna Nowakowska, Dorota Kostrzewa-Nowak, Rafał Buryta, Robert Nowa. Blood Biomarkers of Recovery Efficiency in Soccer Players. International journal of environmental research and public health. vol 16. issue 18. 2020-02-03. PMID:31500120. |
the levels of (ast) (aspartate aminotransferase), (alt) (alanine aminotransferase) and (cr) creatinine were higher in the midfielder/defender group than in the control group, but only ast and cr significantly varied over time (ast decreased, and cr increased with time). |
2020-02-03 |
2023-08-13 |
human |
| Fan Li, Yi-Zhu Dong, Dan Zhang, Xiao-Meng Zhang, Zhi-Jian Lin, Bing Zhan. Molecular mechanisms involved in drug-induced liver injury caused by urate-lowering Chinese herbs: A network pharmacology study and biology experiments. PloS one. vol 14. issue 5. 2020-01-31. PMID:31141540. |
in conclusion, the current research revealed that the compounds with potential liver injury including diosgenin, baicalin, saikosaponin d, tetrandrine, rutaecarpine and evodiamine from urate-lowering chinese herbs, could lead to decline the survival rate of l-02 cell, increase the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and alkaline phosphatase (alp) in cell-culture medium, enhance the expression of p-p38/p38, while the p38 inhibitor could achieve the trend of regulating and controlling liver injury. |
2020-01-31 |
2023-08-13 |
Not clear |
| S Klainbart, M Grabernik, E Kelmer, O Chai, O Cuneah, G Segev, I Aroc. Clinical manifestations, laboratory findings, treatment and outcome of acute organophosphate or carbamate intoxication in 102 dogs: A retrospective study. Veterinary journal (London, England : 1997). vol 251. 2020-01-31. PMID:31492383. |
common laboratory abnormalities included decreased butyrylcholine esterase activity, acidemia, increased total plasma protein, leukocytosis, hypochloridemia, hyperbilirubinemia, increased creatinine and alanine transaminase (alt), aspartate transaminase (ast) and creatine kinase activities, and prolonged activated partial thromboplastin time (aptt). |
2020-01-31 |
2023-08-13 |
Not clear |
| Lin Wang, Xi Cao, Zhenzi Wang, Yuhua Gao, Juan Deng, Xueen Liu, Hui Zhuan. Correlation of HBcrAg with Intrahepatic Hepatitis B Virus Total DNA and Covalently Closed Circular DNA in HBeAg-Positive Chronic Hepatitis B Patients. Journal of clinical microbiology. vol 57. issue 1. 2020-01-30. PMID:30355757. |
serum hbcrag and other parameters, including hbv dna, hbv rna, hbeag, hepatitis b surface antigen (hbsag), hepatitis b core antibody (anti-hbc), alanine aminotransferase (alt), and aspartate aminotransferase (ast) were quantitatively measured at baseline and follow-up time points. |
2020-01-30 |
2023-08-13 |
Not clear |
| S Rashid, M Irshadulla. Evaluation of antioxidant and oxidant status of goats ( Journal of helminthology. vol 94. 2020-01-30. PMID:30761971. |
abomasal tissues from non-infected and infected goats were used for the determination of catalase (cat), glutathione s-transferase (gst), glutathione reductase (gr), glutathione peroxidase (gpx), aspartate (ast) and alanine (alt) aminotransferases, acid (acp) and alkaline (alp) phosphatases, superoxide content (o2-), protein carbonyl (pc), malondialdehyde (mda) and reduced glutathione (gsh). |
2020-01-30 |
2023-08-13 |
cat |
| Yuning Chen, Wen Lu, Zhengyu Jin, Jian Yu, Bimin Sh. Carbenoxolone ameliorates hepatic lipid metabolism and inflammation in obese mice induced by high fat diet via regulating the JAK2/STAT3 signaling pathway. International immunopharmacology. vol 74. 2020-01-28. PMID:31261036. |
blood was collected for detection of triglycerides (tg), total cholesterol (tc), density lipoprotein (ldl), high-density lipoprotein (hdl), alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2020-01-28 |
2023-08-13 |
mouse |
| Jiankang Wang, Yutong He, Deqing Yu, Liang Jin, Xiaobao Gong, Baoshun Zhan. Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 135. 2020-01-27. PMID:31743741. |
pero pretreatment markedly promoted the serum levels of alanine transaminase (alt) and aspartate transaminase alanine (ast) and inhibited the levels of glucose (glu), glucose-6-phosphate dehydrogenase (g6pd), triglycerides (tgs) and total cholesterol (tc). |
2020-01-27 |
2023-08-13 |
mouse |
| Fenghua Yao, Li Zhang, Zhong Yin, Bo Fu, Zhe Feng, Zongze He, Qinggang Li, Jijun Li, Xiangmei Che. The renal level of a novel cytokine IL-35 is related to sepsis-associated acute kidney injury in mice. International journal of clinical and experimental pathology. vol 10. issue 11. 2020-01-26. PMID:31966444. |
blood creatinine (cr), urea nitrogen (bun), alanine transaminase (alt) and aspartate transaminase (ast) were measured to assess kidney and liver injury. |
2020-01-26 |
2023-08-13 |
mouse |
| Qingming Lu, Yan Lu, Ying Zhang, Zhaohui Li, Xiaohua Xi. Establishment and evaluation of rat trauma hemorrhagic liver injury model. International journal of clinical and experimental pathology. vol 10. issue 7. 2020-01-26. PMID:31966574. |
the levels of the following proteins were determined by the enzyme-linked immunosorbent assay (elisa) in our fracture and hemorrhage-based model system: serum alanine transaminase (alt), aspartate aminotransferase (ast), inflammatory cytokines such as interleukin-1β, interleukin-6, and tumor necrosis factor-α, chemokines such as c-c motif ligand 2, c-c motif ligand 5, c-c motif ligand 13, and c-x-c motif ligand 2. |
2020-01-26 |
2023-08-13 |
rat |
| Su-Xia Zheng, Chun-Hui Sun, Jing Che. Cardioprotective effect of indirubin in experimentally induced myocardial infarction in wistar rats. International journal of clinical and experimental pathology. vol 10. issue 7. 2020-01-26. PMID:31966661. |
the iso induced mi injury was confirmed via enhanced level of enzymes markers viz., creatine kinase-mb, creatine kinase, lactate dehydrogensae, troponin-t, alanine transaminase (alt) and aspartate transaminase (ast) in the rats serum. |
2020-01-26 |
2023-08-13 |
rat |
| Wen-Juan Qian, Qing-Hong Chen. Endoplasmic reticulum stress-mediated apoptosis signal pathway is involved in sepsis-induced liver injury. International journal of clinical and experimental pathology. vol 10. issue 9. 2020-01-26. PMID:31966888. |
the levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were detected via colorimetric activity assays. |
2020-01-26 |
2023-08-13 |
rat |
| Asif Zaman, Zarina Arif, Moinuddin, Kafil Akhtar, Wasif Mohammad Ali, Khursheed Ala. A study on hepatopathic, dyslipidemic and immunogenic properties of fructosylated-HSA-AGE and binding of autoantibodies in sera of obese and overweight patients with fructosylated-HSA-AGE. PloS one. vol 14. issue 5. 2020-01-24. PMID:31116779. |
interestingly, alanine aminotransferase (alt), aspartate aminotransferase (ast), bilirubin, total cholesterol (tc) and triglyceride (tg) profiles confirms usg images of overweight, obese patients. |
2020-01-24 |
2023-08-13 |
Not clear |
| Shafinaz Abd Gani, Suleiman Alhaji Muhammad, Aminu Umar Kura, Farahnaz Barahuie, Mohd Zobir Hussein, Sharida Fakuraz. Effect of protocatechuic acid-layered double hydroxide nanoparticles on diethylnitrosamine/phenobarbital-induced hepatocellular carcinoma in mice. PloS one. vol 14. issue 5. 2020-01-24. PMID:31141523. |
deterioration of hepatic cells and a significant increase of aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) were observed in the cancer-induced untreated group compared with that in the groups treated with nanoparticles. |
2020-01-24 |
2023-08-13 |
mouse |
| Ingo Mrosewski, Beate Bredlau, Yusuf Öztürk, Rafael Switkowsk. Persistent Isolated Elevation of Aspartate Aminotransferase in an Asymptomatic Female Patient: a Case Report and Review of Current Literature. Clinical laboratory. vol 65. issue 8. 2020-01-24. PMID:31414761. |
persistent isolated elevation of aspartate aminotransferase (ast) is a rare observation and might lead to unnecessary laboratory testing and invasive procedures, if the possibility of macro-ast is not considered. |
2020-01-24 |
2023-08-13 |
Not clear |
| Yu Jiang, Lianhong Zou, Sulai Liu, Xiehong Liu, Fang Chen, Xiaoliang Liu, Yimin Zh. GC/MS-based metabonomics approach reveals effects of Xuebijing injection in CLP induced septic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 117. 2020-01-22. PMID:31238257. |
the survival rates were monitored for 7d, the effects of xbj on liver and kidney tissue morphology, serum biochemistry [alanine aminotransferase (alt), aspartate aminotransferase (ast), blood urea nitrogen (bun), and creatinine (cr)] and cytokines [tumor necrosis factor-α (tnf-α) and interleukin 6 (il-6)] production were assessed. |
2020-01-22 |
2023-08-13 |
rat |
| Farzin Firouzian, Parisa Pourshoja, Amir Nili-Ahmadabadi, Akram Ranjba. Hepatoprotective effect of N-acetylcystein loaded niosomes on liver function in paraquat-induced acute poisoning. Pesticide biochemistry and physiology. vol 160. 2020-01-21. PMID:31519249. |
alanine (ast) and aspartate (alt) aminotransferase levels, and oxidative stress biomarkers including total antioxidant capacity (tac), lipid peroxidation (lpo), and total thiol groups (ttg) levels were determined. |
2020-01-21 |
2023-08-13 |
rat |
| P Perumal, S Chang, K Khate, K Vupru, S Ba. Flaxseed oil modulates semen production and its quality profiles, freezability, testicular biometrics and endocrinological profiles in mithun. Theriogenology. vol 136. 2020-01-20. PMID:31247386. |
biochemical profiles (aspartate aminotransferase; ast, alanine aminotransferase; alt, total cholesterol; cho), antioxidant profiles (superoxide dismutase; sod, catalase; cat, glutathione; gsh, total antioxidant capacity; tac) and oxidative stress profile (malondialdehyde; mda) were estimated in fresh semen whereas ast, alt, lactate dehydrogenase (ldh), tac and mda were estimated in the frozen thawed semen samples. |
2020-01-20 |
2023-08-13 |
cat |
| S W Odeyemi, J De La Mare, A L Edkins, A J Afolaya. In vitro and in vivo toxicity assessment of biologically synthesized silver nanoparticles from Elaeodendron croceum. Journal of complementary & integrative medicine. vol 16. issue 3. 2020-01-17. PMID:30735482. |
similarly, there was no significant difference (p>0.05) for serum electrolytes (na+, mg2+ k+, cl-, and ca2+), total protein, urea, ɣ-glutamyl transferase (ggt), aspartate aminotransferase (ast), alkaline phosphatase (alp), alanine aminotransferase (alt), albumin, total and conjugated bilirubin between the treatment and the control group. |
2020-01-17 |
2023-08-13 |
rat |
| Muyiwa Samuel Fageyinbo, Abidemi James Akindele, Sunday Oluwaseun Adenekan, Esther Oluwatoyin Agbaj. Evaluation of in-vitro and in-vivo antidiabetic, antilipidemic and antioxidant potentials of aqueous root extract of Strophanthus hispidus DC (Apocynaceae). Journal of complementary & integrative medicine. vol 16. issue 3. 2020-01-17. PMID:31318693. |
blood samples were collected on day 28 for serum biochemical (albumin, total protein [tp], creatinine, alanine transaminase [alt], aspartate transaminase [ast], alkaline phosphatase [alp], triglycerides [tg], total cholesterol [tc], high-density lipoprotein [hdl], low-density lipoprotein [ldl], bilirubin and urea) and hematological assays. |
2020-01-17 |
2023-08-13 |
rat |