| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arezoo Ahmadi, Esfandiar Heidarian, Keihan Ghatreh-Saman. Modulatory effects of artichoke (Cynara scolymus L.) leaf extract against oxidative stress and hepatic TNF-α gene expression in acute diazinon-induced liver injury in rats. Journal of basic and clinical physiology and pharmacology. vol 30. issue 5. 2020-02-21. PMID:31469651. |
after 15 days, serum tumor necrosis factor α (tnf-α), alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), lipid profile, protein carbonyl content, serum and hepatic malondialdehyde (mda), hepatic tnf-α gene expression, hepatic catalase (cat), superoxide dismutase (sod), and vitamin c (vit c) were measured and histopathological examination was performed. |
2020-02-21 |
2023-08-13 |
rat |
| Eun Hye Lee, Su Youn Baek, Ji Young Park, Young Woo Ki. Rifampicin activates AMPK and alleviates oxidative stress in the liver as mediated with Nrf2 signaling. Chemico-biological interactions. vol 315. 2020-02-21. PMID:31678598. |
in vivo, oral administration of rifampicin (100 or 200 mg/kg) attenuated elevation of serum alanine aminotransferase (alt) and aspartate transaminase (ast), serum liver injury markers, against apap treatment and, histologically, ameliorated tissue damage. |
2020-02-21 |
2023-08-13 |
Not clear |
| Shuying Li, Yao Jiang, Qianqian Sun, Scott Coffin, Lili Chen, Kun Qiao, Wenjun Gui, Guonian Zh. Tebuconazole induced oxidative stress related hepatotoxicity in adult and larval zebrafish (Danio rerio). Chemosphere. vol 241. 2020-02-20. PMID:31683439. |
the induction of oxidative stress in adult fish was evaluated by superoxide dismutase (t-sod), catalase (cat), peroxidase (pod), glutathione s-transferase (gst) activity, and the increased aspartate aminotransferase (ast)/alanine aminotransferase (alt) ratio. |
2020-02-20 |
2023-08-13 |
cat |
| Mehdi Zahirian, Alireza Seidavi, Magdalena Solka, Mehran Nosrati, Mirco Corazzi. Dietary supplementation of Aspergillus oryzae meal and its effect on performance, carcass characteristics, blood variables, and immunity of broiler chickens. Tropical animal health and production. vol 51. issue 8. 2020-02-18. PMID:31152336. |
compared with control, ao used during the entire rearing period increased weight gain, reduced relative weight of abdominal fat, aspartate aminotransferase (ast), and alanine aminotransferase (alt) serum levels, and increased antibody titers against influenza and newcastle disease vaccination and sheep red blood cells injection. |
2020-02-18 |
2023-08-13 |
Not clear |
| Thomaz C G de C Rodrigues, Poliane M Freitas, Edson M Santos, Gherman G L de Araújo, Aureliano J V Pires, Maria C C Ayres, Lorendane M de Carvalho, Jocely G Souza, Gleidson G P de Carvalh. Effects of ammoniated pearl millet silage on intake, feeding behavior, and blood metabolites in feedlot lambs. Tropical animal health and production. vol 51. issue 8. 2020-02-17. PMID:31172451. |
increasing urea levels in the silage did not change the blood energy profile (cholesterol and triglycerides) or blood enzyme activity (alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt); p > 0.05). |
2020-02-17 |
2023-08-13 |
Not clear |
| Hong Han, Jiashu Li, Dawei Chen, Feng Zhang, Xin Wan, Changchun Ca. A Clinical Risk Scoring System of Acute Respiratory Distress Syndrome-Induced Acute Kidney Injury. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-14. PMID:31352463. |
the score was allocated in proportion to the corresponding adjusted or, hypertension, ards (moderate-severe), aspartate aminotransferase (ast), d-dimer (2 points each), and unconsciousness (3 points). |
2020-02-14 |
2023-08-13 |
Not clear |
| Liting Zhang, Dan Zhou, Junfeng Li, Xiaoming Yan, Jun Zhu, Ping Xiao, Tuo Chen, Xiaodong Xi. Effects of Bone Marrow-Derived Mesenchymal Stem Cells on Hypoxia and the Transforming Growth Factor beta 1 (TGFβ-1) and SMADs Pathway in a Mouse Model of Cirrhosis. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-14. PMID:31550244. |
results treatment with bm-mscs reduced the expression of alanine aminotransferase (alt) and aspartate aminotransferase (ast) compared with the model group, and reduced liver fibrosis determined histologically using hematoxylin and eosin (h&e) and masson's trichrome staining compared with the model group. |
2020-02-14 |
2023-08-13 |
mouse |
| Jinying Che, Shuo Yang, Zijing Qiao, He Li, Jinghui Sun, Wenyue Zhuang, Jianguang Chen, Chunmei Wan. Schisandra chinensis acidic polysaccharide partialy reverses acetaminophen-induced liver injury in mice. Journal of pharmacological sciences. vol 140. issue 3. 2020-02-13. PMID:31400930. |
scap significantly decreased the serum alanine aminotransferase (alt), aspartate aminotransferas (ast), tumor necrosis factor-α (tnf-α), and interleukin-1β (il-1β) levels, and was found to alleviate hepatic pathological alterations in the mouse model. |
2020-02-13 |
2023-08-13 |
mouse |
| Manal M Sayed, Dalia A Elgamal, Alshaimaa A Farrag, Asmaa M S Goma. Nicotine-induced oxidative stress alters sciatic nerve barriers in rat through modulation of ZO-1 & VEGF expression. Tissue & cell. vol 60. 2020-02-11. PMID:31582019. |
total antioxidant capacity (tac), malondialdehyde (mda), alanine transaminase (alt) and aspartate transaminase (ast) were measured. |
2020-02-11 |
2023-08-13 |
rat |
| Wei Wei, Xiaoning Wu, Jialing Zhou, Yameng Sun, Yuanyuan Kong, Xu Yan. Noninvasive Evaluation of Liver Fibrosis Reverse Using Artificial Neural Network Model for Chronic Hepatitis B Patients. Computational and mathematical methods in medicine. vol 2019. 2020-02-10. PMID:31428186. |
our study manifested that ast (aspartate aminotransferase; importance coefficient = 0.296), plt (platelet count; ic = 0.159), wbc (white blood cell; ic = 0.142), che (cholinesterase; ic = 0.128), lsm (liver stiffness measurement; ic = 0.125), alt (alanine aminotransferase; ic = 0.110), and gender (ic = 0.041) were the most crucial predictors of reverse. |
2020-02-10 |
2023-08-13 |
Not clear |
| Shangyong Li, Ningning He, Linna Wan. Efficiently Anti-Obesity Effects of Unsaturated Alginate Oligosaccharides (UAOS) in High-Fat Diet (HFD)-Fed Mice. Marine drugs. vol 17. issue 9. 2020-02-10. PMID:31533255. |
compared with acid hydrolyzed saturated alginate oligosaccharides (saos), uaos significantly reduced body weight, serum lipid, including triacylglycerol (tg), total cholesterol (tc) and free fatty acids (ffa), liver weight, liver tg and tc, serum alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels, adipose mass, reactive oxygen species (ros) formation, and accumulation induced in hfd mice. |
2020-02-10 |
2023-08-13 |
mouse |
| Hyeong Dong Yuk, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyeon K. De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase) as a Significant Prognostic Factor in Patients Undergoing Radical Cystectomy with Bladder Urothelial Carcinoma: A Propensity Score-Matched Study. Disease markers. vol 2019. 2020-02-10. PMID:31534562. |
to investigate the correlation between preoperative de ritis ratio (aspartate transaminase (ast)/alanine transaminase (alt)) and postoperative outcome in patients with urothelial cell carcinoma (uc) treated with radical cystectomy. |
2020-02-10 |
2023-08-13 |
Not clear |
| Yi Zhao, Youzhi Sun, Gaoyu Wang, Shucao Ge, Hongning Li. Dendrobium Officinale Polysaccharides Protect against MNNG-Induced PLGC in Rats via Activating the NRF2 and Antioxidant Enzymes HO-1 and NQO-1. Oxidative medicine and cellular longevity. vol 2019. 2020-02-07. PMID:31281597. |
alanine aminotransferase (alt), aspartate transaminase (ast), serum creatinine (scr), serum uric acid (ua), blood urea nitrogen (bun), and he staining were detected for liver and kidney function. |
2020-02-07 |
2023-08-13 |
rat |
| Aroon Supramaniam, Helle Bielefeldt-Ohmann, Penny A Rudd, Julie Webster, Vito Ferro, Lara J Herrer. PG545 treatment reduces RRV-induced elevations of AST, ALT with secondary lymphoid organ alterations in C57BL/6 mice. PloS one. vol 14. issue 6. 2020-02-06. PMID:31170255. |
previously unreported, rrv-induced elevations of aspartate aminotransferase (ast) and alanine transaminase (alt) enzymes and creatinine were also noted in the rrv-infected mice. |
2020-02-06 |
2023-08-13 |
mouse |
| Laura Menchetti, Gabriella Guelfi, Roberto Speranza, Pasquale Carotenuto, Livia Moscati, Silvana Diveri. Benefits of dietary supplements on the physical fitness of German Shepherd dogs during a drug detection training course. PloS one. vol 14. issue 6. 2020-02-06. PMID:31199843. |
the supplemented dogs showed the lowest concentrations of creatine kinase (ck; p<0.001), aspartate aminotransferase (ast, p<0.05) and non-esterified fatty acids (nefa; p<0.01) suggesting a reduction in muscle damage and improvement of energy metabolism. |
2020-02-06 |
2023-08-13 |
human |
| Xiao Guo, Chengzhan Zhu, Xiaojun Liu, Yiping Ge, Xianyan Jiang, Wei Zha. Hyperoside protects against heart failure-induced liver fibrosis in rats. Acta histochemica. vol 121. issue 7. 2020-02-06. PMID:31353051. |
moreover, hyperoside could attenuate liver fibrosis and injury in acf rats, as evidenced by reduction of fibrosis area and hydroxyproline content, amelioration of edema and degeneration of liver cell vacuoles, and inhibition of alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) levels. |
2020-02-06 |
2023-08-13 |
rat |
| Mahdi Yaghchiyan, Leila Roshangar, Mahdieh Abbasalizad Farhangi, Mehran Mesgari-Abbasi, Leila Rafiei, Parviz Shahab. Histologic, Metabolic, and Inflammatory Changes in the Liver of High-fat Diet-induced Obese Rats before and after Vitamin D Administration. Iranian journal of allergy, asthma, and immunology. vol 18. issue 4. 2020-02-05. PMID:31522448. |
moreover, a significant reduction in the serum levels of aspartate amino transferase (ast) and alanine amino transferase (alt) in vitamin d treated groups was identified (p<0.05). |
2020-02-05 |
2023-08-13 |
rat |
| Xiao-Ping Wang, Peng-Fei Wang, Ji-Qing Bai, Su Gao, Ya-Heng Wang, Li-Na Quan, Fang Wang, Xiao-Ting Wang, Jin Wang, Yun-Dong Xi. Investigating the effects and possible mechanisms of danshen- honghua herb pair on acute myocardial ischemia induced by isoproterenol in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 118. 2020-02-05. PMID:31545239. |
the results suggested that dhhp significantly ameliorated the myocardial tissue abnormalities, notablely inhibited the elevation of lactate dehydrogenase (ldh), creatine kinase (ck), aspartate aminotransferase (ast), creatinekinase isoenzyme (ck-mb) and cardiac troponin t (ctn-t) in plasma, obviously decreased the plasma levels of tumor necrosis factor α (tnf-α), outstandingly inhibited the reduction of superoxide dismutase (sod), catalase (cat) caused by iso, significantly inhibited the high expression of bcl-2 assaciated x protein (bax) and nuclear transcriptionfactor-κbp65 (nf-κbp65) protein, significantly induced the low expression of b-cell lymphoma-2 (bcl-2) protein in acute myocardial ischemia rats. |
2020-02-05 |
2023-08-13 |
rat |
| Hong-Miao Xia, Jin Wang, Xiao-Jie Xie, Li-Juan Xu, Shi-Qi Tan. Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats. International journal of molecular medicine. vol 44. issue 4. 2020-02-04. PMID:31364723. |
the levels of alanine aminotransferase (alt), aspartate amino-transferase (ast) and inflammatory cytokines in the serum, as well as oxidative stress markers and hepatic lipids in the liver were measured. |
2020-02-04 |
2023-08-13 |
rat |
| Guo Li, Shanshan Huang, Lifei Lian, Xiaoyan Song, Wenzhe Sun, Jinfeng Miao, Bohan Li, Yong Yuan, Shengfan Wu, Xiaoyan Liu, Zhou Zh. Derivation and external validation of a model to predict 2-year mortality risk of patients with advanced schistosomiasis after discharge. EBioMedicine. vol 47. 2020-02-04. PMID:31451437. |
we constructed 4 models based on the 7 selected variables: age, clinical classification, serum direct bilirubin (dbil), aspartate aminotransferase (ast), alkaline phosphatase (alp), hepatitis b surface antigen (hbsag), alpha fetoprotein (afp) at admission. |
2020-02-04 |
2023-08-13 |
Not clear |