| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Lelorier, F E Shidema. Acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. The Journal of pharmacy and pharmacology. vol 28. issue 3. 1976-08-23. PMID:6692. |
acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. |
1976-08-23 |
2023-08-11 |
chicken |
| J Lelorier, F E Shidema. Acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. The Journal of pharmacy and pharmacology. vol 28. issue 3. 1976-08-23. PMID:6692. |
three and 4 day old embryonic chicken hearts were examined for their responsiveness to acetylcholine and presence of acetylcholinesterase (ache) to determine the role of the enzyme in the cardiac effects of the transmitter. |
1976-08-23 |
2023-08-11 |
chicken |
| B Désiré, G Blanchet, G Definod, R Arnau. [Acetylcholinesterase. II. Experimental aspects of interaction with reversible effectors under conditions of high ionic strength]. Biochimie. vol 57. issue 11-12. 1976-07-06. PMID:4154. |
detailed kinetic investigation of the hydrolysis of acetylcholine by acetylcholinesterase in the presence of modifiers shows that the effects produced by numerous quaternary nitrogen compounds on the enzyme can be explained on the basis of binding of the effectors to the anionic subsite of the active center. |
1976-07-06 |
2023-08-11 |
cattle |
| J G Clement, E H Colhou. Inhibition of choline transport into human erythrocytes by choline mustard aziridinium ion. Canadian journal of physiology and pharmacology. vol 53. issue 6. 1976-07-06. PMID:177158. |
it is concluded that acetylcholinesterase (ec 3.1.1.7) of red cells rapidly hydrolyzes acetylcholine mustard aziridinium ion to acetate and choline mustard aziridinium and the latter compound can act as a potent inhibitor of choline transport. |
1976-07-06 |
2023-08-11 |
mouse |
| K G Lloy. Special chemistry of the basal ganglia 2. Distribution of acetylcholine, choline acetyltransferase and acetylcholinesterase. Pharmacology & therapeutics. Part B: General & systematic pharmacology. vol 1. issue 1. 1976-07-06. PMID:817321. |
distribution of acetylcholine, choline acetyltransferase and acetylcholinesterase. |
1976-07-06 |
2023-08-11 |
Not clear |
| A K Ho, C S Tsai, B Kissi. Neurochemical correlates of alcohol preference in inbred strains of mice. Pharmacology, biochemistry, and behavior. vol 3. issue 6. 1976-07-06. PMID:1223897. |
brain content of acetylcholine, uptake of 14c-choline by whole brain homogenate were significantly higher in the c57b1/6j mice whereas brain acetylcholinesterase was higher in the dba/2j mice. |
1976-07-06 |
2023-08-11 |
mouse |
| J K Reed, M A Rafter. Properties of the tetrodotoxin binding component in plasma membranes isolated from Electrophorus electricus. Biochemistry. vol 15. issue 5. 1976-06-02. PMID:3213. |
membrane fragments from the electroplaque were isolated essentially by differential centrifugation and characterized with respect to the plasma membrane markers acetylcholine receptors, acetylcholinesterase, (na+ + k+)atpase, and [3h]ttx binding. |
1976-06-02 |
2023-08-11 |
Not clear |
| T Bartfai, P Berg, M Schultzberg, E Heilbron. Isolation of a synaptic membrane fraction enriched in cholinergic receptors by controlled phospholipase A2 hydrolysis of synaptic membranes. Biochimica et biophysica acta. vol 426. issue 2. 1976-05-25. PMID:1252506. |
a procedure is described for the isolation of synaptic membrane fragments that retain such functionally important proteins as acetylcholine receptors, acetylcholinesterase, 3',5'-cyclic nucleotide phosphodiesterase, and (na+ + k+)-atpase. |
1976-05-25 |
2023-08-11 |
cattle |
| B Désiré, G Blanche. [The interaction of acetylcholinesterase with thioridazine chlorohydrate and thiazinamium methylsulfate]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. vol 281. issue 15. 1976-04-23. PMID:813887. |
in reaction mixture containing 0,1 m nacl and acetylcholine used as substrate, the kinetics of the inhibition of bovine erythrocyte acetylcholinesterase (ec 3.1.1.7) by thioridazine hydrochloride and thiazinamium methylsulfate imply the simultaneous binding of two thioridazine or thiazinamium molecules at the free enzyme and of two thioridazine molecules at the acetylated enzyme. |
1976-04-23 |
2023-08-11 |
cattle |
| E R Martínez de Melían, R D Morero, R N Faría. Multiple forms of acetylcholinesterase from rat erythrocytes. Effect of fat-free diet. Biochimica et biophysica acta. vol 422. issue 1. 1976-04-19. PMID:1247591. |
electrophoretic patterns of acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) from rat erythrocyte were studied. |
1976-04-19 |
2023-08-11 |
rat |
| S M Pojd. [Acetylcholine content and acetylcholinesterase activity of the retina in white rats with experimental hyperlipemia]. Klinika oczna. vol 45. issue 12. 1976-04-09. PMID:1214442. |
[acetylcholine content and acetylcholinesterase activity of the retina in white rats with experimental hyperlipemia]. |
1976-04-09 |
2023-08-11 |
rat |
| Y Kimhi, C Palfrey, I Spector, Y Barak, U Z Littaue. Maturation of neuroblastoma cells in the presence of dimethylsulfoxide. Proceedings of the National Academy of Sciences of the United States of America. vol 73. issue 2. 1976-04-02. PMID:1756. |
a high degree of electrical excitability was found in these cells, but there was no clear correlation of this property with the level of induction of either acetylcholinesterase (acetylcholine hydrolase; ec 3.1.1.7) or tyrosine hydroxylase [l-tyrosine, tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating); ec 1.14.16.2]. |
1976-04-02 |
2023-08-11 |
mouse |
| G N Mirotvorskai. [A histochemical study of brain tissue in experimental convulsive seizures (componetns of acetylcholine metabolism)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 75. issue 7. 1976-04-01. PMID:1210983. |
the author studied substances related to acetylcholine metabolism (acetylcholinesterase, non-specific acetylcholinesterase, sh, ss-groups, histidine, ca) using histochemical methods. |
1976-04-01 |
2023-08-11 |
Not clear |
| J S Meyer, E O Ott, M Aoyagi, Y Kawamura, Y Tagashir. [Double cholinergic and adrenergic regulation of cerebral blood flow]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 61. issue 10. 1976-03-11. PMID:812735. |
cerebral vascular tonus was measurably influenced by both alpha or beta adrenergic blockade and by inhibition of cerebrovascular acetylcholine or acetylcholinesterase. |
1976-03-11 |
2023-08-11 |
Not clear |
| T L Rosenberr. Catalysis by acetylcholinesterase: evidence that the rate-limiting step for acylation with certain substrates precedes general acid-base catalysis. Proceedings of the National Academy of Sciences of the United States of America. vol 72. issue 10. 1976-03-01. PMID:668. |
inferences about the catalytic mechanism of acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) are frequently made on the basis of a presumed analogy with chymotrypsin, ec 3.4.21.1. |
1976-03-01 |
2023-08-11 |
Not clear |
| P D Hrdina, P K Ghosh, R B Rastogi, R L Singha. Ontogenic pattern of dopamine, acetylcholine, and acetylcholinesterase in the brains of normal and hypothyroid rats. Canadian journal of physiology and pharmacology. vol 53. issue 5. 1976-03-01. PMID:1201478. |
ontogenic pattern of dopamine, acetylcholine, and acetylcholinesterase in the brains of normal and hypothyroid rats. |
1976-03-01 |
2023-08-11 |
rat |
| P D Hrdina, P K Ghosh, R B Rastogi, R L Singha. Ontogenic pattern of dopamine, acetylcholine, and acetylcholinesterase in the brains of normal and hypothyroid rats. Canadian journal of physiology and pharmacology. vol 53. issue 5. 1976-03-01. PMID:1201478. |
the influence of neonatal thyroidectomy (tx) on developmental changes in dopamine (da), acetylcholine (ach), and acetylcholinesterase (ache) was studied in the whole brain of rats. |
1976-03-01 |
2023-08-11 |
rat |
| R M Krupk. Differential effects of denaturing agents on acetylcholinesterase: insensitivity of the reaction of methanesulfonyl fluoride compared to diisopropylphosphorofluoridate and p-nitrophenyl acetate. Biochimica et biophysica acta. vol 410. issue 1. 1976-02-13. PMID:172135. |
the effects of various agents that could be expected to perturb enzyme structure in a non-specific and reversible manner (alcohols, dimethylsulfoxide, dimethylformamide, dinitrobenzene, urea and guanidine - hcl) have been determined on reaction of acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) with a substrate, p-nitrophenyl acetate, and two irreversible inhibitors, diisopropylphosphorofluoridate and methanesulfonyl fluoride. |
1976-02-13 |
2023-08-11 |
Not clear |
| R M Krupk. Indophenyl acetate and acetylcholinesterase: binding of a non-specific substrate on the margin of the active center. Biochimica et biophysica acta. vol 410. issue 1. 1976-02-13. PMID:1238116. |
indophenyl acetate is a very poor substrate of eel or bovine acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7), with a v less than 5% of that of phenyl acetate, but it is a labile ester and in imidazole buffer is hydrolyzed, non-enzymically, even faster than phenyl acetate. |
1976-02-13 |
2023-08-11 |
cattle |
| J A Maglothin, P Wins, I B Wilso. Reactivation and aging of diphenyl phosphoryl acetylcholinesterase. Biochimica et biophysica acta. vol 403. issue 2. 1976-01-29. PMID:241402. |
acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) is readily in hibited by 10(-5) m diphenylphosphorochloridate even though the inhibitor hydrolyzes in a few seconds. |
1976-01-29 |
2023-08-11 |
Not clear |