| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Reiner, V Simeo. Competition between substrates for acetylcholinesterase and cholinesterase. Biochimica et biophysica acta. vol 480. issue 1. 1977-03-31. PMID:831831. |
the kinetics of competition of pairs of two substrates for bovine erythrocyte acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) and horse serum cholinesterase (acylcholine acyl-hydrolase, ec 3.1.1.8) was studied so that the hydrolysis of only one substrate was measured at a time. |
1977-03-31 |
2023-08-11 |
cattle |
| R M Dawso. Inactivation of acetylcholinesterase by propanol and sodium dodecyl sulphate. Biochimica et biophysica acta. vol 452. issue 2. 1977-03-21. PMID:1009118. |
departure from first-order kinetics was observed for the inactivation of bovine erythrocyte and electric eel acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) by n-propanol. |
1977-03-21 |
2023-08-11 |
cattle |
| F R Domer, D M Chihal, H C Charles, A B Reg. Effect of sulfur substitution for the noncarbonyl oxygen in hemicholinium-3 and acetyl-seco-hemicholinium-3. Synthesis, biological activity, and structure-toxicity relationships. Journal of medicinal chemistry. vol 20. issue 1. 1977-03-15. PMID:833827. |
as expected on the basis of conformational differences between acetylcholine and acetylthiocholine both of the thio analogues are produced in the seco form and do not cyclize spontaneously or when subjected to aqueous, acidic conditions up to 100 degrees c. both compounds are stable in aqueous ph 7.4 solutions at 37 degrees c and in slightly acidic d2o solutions for more than 24 h. while thio-seco-hemicholinium 3 (11) is stable in the presence of acetylcholinesterase and butyrylcholinesterase in h2o at ph 7.4, acetylthio-seco-hemicholinium-3 (12) reacts within seconds to form the hemiacetal form of thiohemicholinium-3 (16). |
1977-03-15 |
2023-08-11 |
mouse |
| J R Sanes, D J Prescott, J G Hildebran. Cholinergic neurochemical development of normal and deafferented antennal lobes during metamorphosis of the moth, Manduca sexta. Brain research. vol 119. issue 2. 1977-02-26. PMID:830392. |
levels of acetylcholine, choline acetyltransferase, and acetylcholinesterase rise dramatically in the lobes as sensory axons grow from the antennae to the lobes through the antennal nerves. |
1977-02-26 |
2023-08-11 |
Not clear |
| J R Sanes, D J Prescott, J G Hildebran. Cholinergic neurochemical development of normal and deafferented antennal lobes during metamorphosis of the moth, Manduca sexta. Brain research. vol 119. issue 2. 1977-02-26. PMID:830392. |
levels of acetylcholine, choline acetyltransferase, and acetylcholinesterase, but not of toxin-binding activity, are greatly reduced in lobes deafferented by amputation of developing antennae. |
1977-02-26 |
2023-08-11 |
Not clear |
| F T Schu. [Cholinesterases--a group of enzymes important to the anaesthesiologist (author's transl)]. Der Anaesthesist. vol 25. issue 11. 1977-02-16. PMID:1008237. |
acetylcholinesterase is structurally bound at the cholinergic synaptic junction being of physiological significance for hydrolyzing the transmitter substance acetylcholine. |
1977-02-16 |
2023-08-11 |
human |
| A Ebel, R Jaffard, C Destrade, G Ayad, P Mandel, B Card. [Changes in cholinergic mechanisms and in learning in three strains of inbred mice after electric stimulation of the dorsal hippocampus]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. vol 283. issue 5. 1977-01-29. PMID:825302. |
the second experiment was aimed at studying the stimulation effect on hippocampal cholinergic mechanisms by testing the two main enzymes involved in acetylcholine synthesis and degradation (choline acetyltransferase = chac and acetylcholinesterase = ache). |
1977-01-29 |
2023-08-11 |
mouse |
| P D Hrdina, D A Peters, R L Singha. Effects of chronic exposure to cadmium, lead and mercury of brain biogenic amines in the rat. Research communications in chemical pathology and pharmacology. vol 15. issue 3. 1977-01-29. PMID:996361. |
effects of chronic (45 days) treatment with different doses of cadmium chloride (0.25 and 1.0 mg/kg/day), methylmercury chloride (0.4 and 4.0 mg/kg/day) and lead acetate (0.2 and 1.0 mg/kg/day) and of 28-day withdrawal of treatment on the levels of acetylcholine (ach) and activity of acetylcholinesterase (ache) in cerebral cortex, and concentration of norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in brain-stem were examined in rats. |
1977-01-29 |
2023-08-11 |
rat |
| Z S Herman, A Sokola, H Lenartowicz, M Zieliński, L Dept. The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats. Polish journal of pharmacology and pharmacy. vol 28. issue 4. 1976-12-30. PMID:981020. |
the influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats. |
1976-12-30 |
2023-08-11 |
rat |
| Z S Herman, A Sokola, H Lenartowicz, M Zieliński, L Dept. The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats. Polish journal of pharmacology and pharmacy. vol 28. issue 4. 1976-12-30. PMID:981020. |
rats were treated ip with mao inhibitos (mao-i): nialamid (nl), pivalylbenzylhydrazine, tranylcypromine, pheniprazine (ph) or pargyline, and the leve of total, free and bound acetylcholine (ach) as well as the acetylcholinesterase (ach-e) activity were estimated in four parts of rats brain 2 or 16 hr after the treatment. |
1976-12-30 |
2023-08-11 |
rat |
| G A Ruch, G B Koell. Effect of preganglionic application of vinblastine-impregnated silastic cuffs on acetylcholinesterase, butyrocholinesterase, and acetylcholine contents of cat superior cervical ganglion. Experimental neurology. vol 53. issue 2. 1976-12-23. PMID:976413. |
effect of preganglionic application of vinblastine-impregnated silastic cuffs on acetylcholinesterase, butyrocholinesterase, and acetylcholine contents of cat superior cervical ganglion. |
1976-12-23 |
2023-08-11 |
cat |
| M G McConnell, L L Simpso. The role of acetylcholine receptors and acetylcholinesterase activity in the development of denervation supersensitivity. The Journal of pharmacology and experimental therapeutics. vol 198. issue 3. 1976-12-23. PMID:978456. |
the role of acetylcholine receptors and acetylcholinesterase activity in the development of denervation supersensitivity. |
1976-12-23 |
2023-08-11 |
rat |
| M G McConnell, L L Simpso. The role of acetylcholine receptors and acetylcholinesterase activity in the development of denervation supersensitivity. The Journal of pharmacology and experimental therapeutics. vol 198. issue 3. 1976-12-23. PMID:978456. |
the data suggest that both an increase in acetylcholine receptors and a decrease in acetylcholinesterase activity contribute to the phenomenon of denervation supersensitivity. |
1976-12-23 |
2023-08-11 |
rat |
| C E Reed, W W Busse, T P Le. Adrenergic mechanisms and the adenyl cyclase system in atopic dermatitis. The Journal of investigative dermatology. vol 67. issue 3. 1976-11-21. PMID:9456. |
their lesions have been reported to contain increased amounts of the neurohumors, acetylcholine and norepinephrine, as well as increased activity of acetylcholinesterase and catechol-o-methyltransferase. |
1976-11-21 |
2023-08-11 |
Not clear |
| R W Steele, B N Smallma. Acetylcholinesterase from the house-fly head. Molecular properties of soluble forms. Biochimica et biophysica acta. vol 445. issue 1. 1976-10-29. PMID:953030. |
polyacrylamide gel electrophoresis in tris/glycine buffer (ph 8.3) revealed five forms of acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) in the 100 000 x g, 1-h supernatants of aqueous fly-head extracts from the ddt/s strain. |
1976-10-29 |
2023-08-11 |
Not clear |
| R W Steele, B N Smallma. Acetylcholinesterase of the house-fly head. Affinity purification and subunit composition. Biochimica et biophysica acta. vol 445. issue 1. 1976-10-29. PMID:953031. |
acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7) of house-fly head tissue was solubilized as a 7.4-s form by autolysis for 80-100 h at 25 degrees c and ph 8.0. |
1976-10-29 |
2023-08-11 |
Not clear |
| R Gentinetta, U Brodbec. Differences in subunit activities in acetylcholinesterase as possible cause for apparent deviation from normal Michaelis-Menten kinetics. Biochimica et biophysica acta. vol 438. issue 2. 1976-10-20. PMID:952942. |
form gp of acetylcholinesterase (ec 3.1.1.7) from electric eel gave curved lineweaver-burk plots with acetylcholine. |
1976-10-20 |
2023-08-11 |
Not clear |
| D A Buxton, R W Brimblecombe, M C French, P H Redfer. Brain acetylcholine concentration and acetylcholinesterase activity in selectively-bred strains of rats. Psychopharmacology. vol 47. issue 1. 1976-10-20. PMID:959469. |
brain acetylcholine concentration and acetylcholinesterase activity in selectively-bred strains of rats. |
1976-10-20 |
2023-08-11 |
rat |
| W A Koelle, G B Koelle, E G Smyr. Effects of persistent selective suppression of ganglionic butyrylcholinesterase on steady state and regenerating levels of acetylcholinesterase: implications regarding function of butyrylcholinesterase and regulation of protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. vol 73. issue 8. 1976-10-20. PMID:1066704. |
persistent selective suppression of the butyrylcholinesterase (cholinesterase; acylcholine acyl-hydrolase, ec 3.1.1.8) activity of the superior cervical, stellate, and ciliary ganglia of cats by the daily administration of tetramonoisopropyl pyrophosphortetramide, 3.0 mumol/kg, intravenously, for 6 days produced a significant elevation in the levels of ganglionic acetylcholinesterase (acetylcholine hydrolase, ec 3.1.1.7). |
1976-10-20 |
2023-08-11 |
Not clear |
| P K Das, E H L. Heterogeneity of human erythrocyte acetylcholinesterase. Individual variation revealed by DEAE-cellulose chromatography and polyacrylamide gel disc electrophoresis. Enzyme. vol 21. issue 4. 1976-09-25. PMID:939223. |
acetylcholinesterase (eache; acetylcholine acetyl hydrolase, ec 3.1.1.7) was prepared from the erythrocyte membrane of chinese adult males, and solubilised with 1% triton x-100 in 20 mmol/l phosphate buffer, ph 7.4. |
1976-09-25 |
2023-08-11 |
human |