All Relations between acetylcholinesterase and acetylcholine

Publication Sentence Publish Date Extraction Date Species
Liyuan Guo, Zelei Chang, Jianbo Tong, Peng Gao, Yakun Zhang, Yuan Liu, Yulu Yang, Chunying Wan. Design of vilazodone-donepezil chimeric derivatives as acetylcholinesterase inhibitors by QSAR, molecular docking and molecular dynamics simulations. Physical chemistry chemical physics : PCCP. 2024-06-19. PMID:38896464. acetylcholinesterase (ache) can increase acetylcholine concentrations and improve cognitive function in patients, and is a potential target to develop small molecule inhibitors for the treatment of alzheimer's disease (ad). 2024-06-19 2024-06-21 Not clear
Leonardo F de Sousa, Diego F S Paschoal, Willian T G Novat. Molecular modeling of multi-target analogs of huperzine A and applications in Alzheimer's disease. Journal of molecular modeling. vol 30. issue 7. 2024-06-08. PMID:38850372. moreover, inhibiting acetylcholinesterase represents a pivotal strategy to enhance acetylcholine levels in the synaptic cleft. 2024-06-08 2024-06-11 Not clear
Yashika Sarangle, Kiran Bamel, Ram Singh Purt. Role of acetylcholine and acetylcholinesterase in improving abiotic stress resistance/tolerance. Communicative & integrative biology. vol 17. issue 1. 2024-06-03. PMID:38827581. role of acetylcholine and acetylcholinesterase in improving abiotic stress resistance/tolerance. 2024-06-03 2024-06-05 Not clear
Yashika Sarangle, Kiran Bamel, Ram Singh Purt. Role of acetylcholine and acetylcholinesterase in improving abiotic stress resistance/tolerance. Communicative & integrative biology. vol 17. issue 1. 2024-06-03. PMID:38827581. acetylcholine hydrolyzing enzyme acetylcholinesterase (ache) belongs to the gdsl lipase/acylhydrolase protein family and has been found in several plant species. 2024-06-03 2024-06-05 Not clear
Haiyan Hao, Ailong Sh. Study on Anti-fatigue Effects and Mechanisms of Polysaccharide from Paris polyphylla. Doklady. Biochemistry and biophysics. vol 516. issue 1. 2024-05-25. PMID:38722403. the effects of pppm-1 on the contents of blood lactate, serum urea nitrogen, hepatic glycogen, muscle glycogen in the exercise fatigue model of mice, and acetylcholine (ach) content and acetylcholinesterase (ache) activity at the junction of the frog sciatic nerve-gastrocnemius under normal physiological, and na 2024-05-25 2024-05-27 mouse
Tamara Bernauer, Valentin Nitsche, Jesko Kaiser, Christoph G W Gertzen, Georg Höfner, Karin V Niessen, Thomas Seeger, Dirk Steinritz, Franz Worek, Holger Gohlke, Klaus T Wanner, Franz F Paintne. Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents. Toxicology letters. 2024-05-17. PMID:38759939. poisoning with organophosphorus compounds, which can lead to a cholinergic crisis due to the inhibition of acetylcholinesterase and the subsequent accumulation of acetylcholine (ach) in the synaptic cleft, is a serious problem for which treatment options are currently insufficient. 2024-05-17 2024-05-27 rat
Yuxin Zhang, Xiaoqing Pei, Lingyang Jing, Qingyu Zhang, Hongfeng Zha. Lead induced cerebellar toxicology of developmental Japanese quail (Coturnix japonica) via oxidative stress-based Nrf2/Keap1 pathway inhibition and glutathione-mediated apoptosis signaling activation. Environmental pollution (Barking, Essex : 1987). vol 352. 2024-05-10. PMID:38718965. moreover, cerebellar neurotransmission was disturbed by pb with increasing acetylcholine (ach) and decreasing acetylcholinesterase (ache), dopamine (da), γ-aminobutyric acid (gaba) and na 2024-05-10 2024-05-27 Not clear
Dayan Liu, Tao Song, Kang Na, Shudong Wan. PED: a novel predictor-encoder-decoder model for Alzheimer drug molecular generation. Frontiers in artificial intelligence. vol 7. 2024-05-01. PMID:38690194. acetylcholinesterase (ache) is an efficient hydrolase that catalyzes the hydrolysis of acetylcholine (ach), which regulates the concentration of ach at synapses and then terminates ach-mediated neurotransmission. 2024-05-01 2024-05-03 Not clear
Qiyun Wu, Yingjie Xia, Maggie Suisui Guo, Tsz Yu Au, Gary K W Yuen, Ivan Kong, Zhengqi Wang, Yingyi Lin, Tina T X Dong, Karl W K Tsi. Acetylcholinesterase is regulated by exposure of ultraviolet B in skin keratinocytes: A potential inducer of cholinergic urticaria. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 9. 2024-05-01. PMID:38690717. this skin problem is hypothesized to be attributed to a reduced expression of acetylcholinesterase (ache), an enzyme responsible for hydrolyzing acetylcholine (ach). 2024-05-01 2024-05-03 Not clear
Al-Sayeda Al-Sayed Newairy, Fatma Ahmad Hamaad, Mayssaa Moharm Wahby, Mamdooh Ghoneum, Heba Mohamed Abdo. Neurotherapeutic effects of quercetin-loaded nanoparticles and Biochanin-A extracted from Trifolium alexandrinum on PI3K/Akt/GSK-3β signaling in the cerebral cortex of male diabetic rats. PloS one. vol 19. issue 4. 2024-04-29. PMID:38683825. in addition, these treatments improved neurochemical levels, including acetylcholine, dopamine, and serotonin levels as well acetylcholinesterase and monoamine oxidase activities. 2024-04-29 2024-05-03 rat
Zhi Luo, Zhi-Yu Lin, Zhen-Fei Li, Zhen-Qiang Fu, Feng-Lu Han, Er-Chao L. Next-Generation Neonicotinoid: The Impact of Cycloxaprid on the Crustacean Decapod Penaeus vannamei. Chemosphere. 2024-04-28. PMID:38679174. notably, analyses of the nervous system revealed marked disturbances in neural signaling, as evidenced by elevated acetylcholine, octopamine, and acetylcholinesterase levels. 2024-04-28 2024-05-01 Not clear
Ali Hassan, Lidong Kang, Kaixiong Zhang, Lei Wang, Xianjiao Qin, Guobin Fang, Yongyue Lu, Qiuying Huan. Effect of entomopathogenic fungi on behavior and physiology of Solenopsis invicta (Hymenoptera, Formicidae). Journal of economic entomology. 2024-04-18. PMID:38634604. the activity of acetylcholinesterase, which hydrolyses the important neurotransmitter acetylcholine, also decreased after fungal application compared to the control. 2024-04-18 2024-04-20 Not clear
Juan David Villeda-González, José Luis Gómez-Olivares, Luis Arturo Baiza-Gutma. New paradigms in the study of the cholinergic system and metabolic diseases: Acetyl-and-butyrylcholinesterase. Journal of cellular physiology. 2024-04-12. PMID:38605655. acetylcholinesterase (ache) and butyrylcholinesterase (bche) are enzymes that belong to the neuromuscular cholinergic system, their main function is to hydrolyze the neurotransmitter acetylcholine (ach), through their hydrolysis these enzymes regulate the neuronal and neuromuscular cholinergic system. 2024-04-12 2024-04-14 Not clear
Maciej Zadrozny, Patrycja Drapich, Anna Gasiorowska-Bien, Wiktor Niewiadomski, Charles R Harrington, Claude M Wischik, Gernot Riedel, Grazyna Niewiadomsk. Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model. Cells. vol 13. issue 7. 2024-04-12. PMID:38607082. immunohistochemical staining and quantification of choline acetyltransferase (chat), tyrosine kinase a (trka)-positive neurons and relative optical intensity (roi) for vesicular acetylcholine transporter (vacht), and acetylcholinesterase (ache) reactivity confirmed reversal of the diminished cholinergic phenotype of interneurons (nucleus accumbens, striatum) and projection neurons (medial septum, nucleus basalis magnocellularis) by hmtm, to a greater extent than by rivastigmine alone in l1 mice. 2024-04-12 2024-04-14 mouse
Surbhi Jaiswal, Brijeshwar Singh, Isha Dhingra, Abhijeet Joshi, Prashant Kodgir. Bioremediation and Bioscavenging for elimination of Organophosphorus threats: An approach using enzymatic advancements. Environmental research. 2024-04-10. PMID:38599448. these compounds inhibit the action of the acetylcholinesterase enzyme (ache) by phosphorylation, which prevents the breakdown of acetylcholine (ach) neurotransmitters into choline and acetate. 2024-04-10 2024-04-13 human
Gumpeny R Sridhar, Lakshmi Gumpen. Emerging significance of butyrylcholinesterase. World journal of experimental medicine. vol 14. issue 1. 2024-04-09. PMID:38590305. its other functions include the ability to hydrolyze acetylcholine, the cholinergic neurotransmitter in the brain, when its primary hydrolytic enzyme, acetylcholinesterase, is absent. 2024-04-09 2024-04-11 human
Jae Yeon Park, Seong Doo Kang, Yun Gon Son, Ju Yeon Kim, Gihwan Lee, Kwang Dong Kim, Sang Won Lee, Jeong Yoon Ki. Eucalyptus globulus leaf-isolated isorhapontin serves as a natural insecticide via acetylcholinesterase inhibition. Pesticide biochemistry and physiology. vol 200. 2024-04-08. PMID:38582576. acetylcholinesterase (ache) inhibitors cause insect death by preventing the hydrolysis of the neurotransmitter acetylcholine, which overstimulates the nervous system. 2024-04-08 2024-04-10 Not clear
Francesco Samarelli, Rosa Purgatorio, Gianfranco Lopopolo, Caterina Deruvo, Marco Catto, Michael Andresini, Antonio Carrieri, Orazio Nicolotti, Annalisa De Palma, Daniela Valeria Miniero, Modesto de Candia, Cosimo D Altomar. Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults. European journal of medicinal chemistry. vol 270. 2024-04-05. PMID:38579622. due to the putative role of butyrylcholinesterase (bche) in regulation of acetylcholine levels and functions in the late stages of the alzheimer's disease (ad), the potential of selective inhibitors (bcheis) has been envisaged as an alternative to administration of acetylcholinesterase inhibitors (acheis). 2024-04-05 2024-04-10 Not clear
A Saud, V Krishnaraju, A Taha, K Kalpana, V Malarkodi, S Durgaramani, V Vinoth Prabhu, F A Saleh, S Ezhilarasa. Potential acetylcholinesterase inhibitors to treat Alzheimer's disease. European review for medical and pharmacological sciences. vol 28. issue 6. 2024-04-03. PMID:38567612. acetylcholinesterase is an enzyme that breaks down acetylcholine to an inactive form and causes the death of cholinergic neurons. 2024-04-03 2024-04-05 Not clear
Nkolika Odenigbo, Stanley Nkemjika, Ayodele Atolagbe, Christian Nwabueze, Connie Olwit, Jeffery Lawrence, Tolulope Olupon. Donepezil-induced bradycardia in a schizophrenic patient with comorbid neurocognitive disorder: a case report and review of the literature. Journal of medical case reports. vol 18. issue 1. 2024-03-27. PMID:38532522. donepezil is an acetylcholinesterase inhibitor that improves cognition by preventing postsynaptic degradation of hippocampal acetylcholine in patients with mild-to-moderate dementia. 2024-03-27 2024-03-29 Not clear