All Relations between 5-ht receptor and serotonin

Publication Sentence Publish Date Extraction Date Species
Navoda Jayakodiarachchi, Mallory A Maurer, Daniel C Schultz, Cayden J Dodd, Analisa Thompson Gray, Hyekyung P Cho, Olivier Boutaud, Carrie K Jones, Craig W Lindsley, Aaron M Bende. Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists. ACS medicinal chemistry letters. vol 15. issue 2. 2024-02-14. PMID:38352850. herein, we report the synthesis and characterization of a novel set of substituted indazole-ethanamines and indazole-tetrahydropyridines as potent serotonin receptor subtype 2 (5-ht 2024-02-14 2024-02-16 Not clear
O Aung, Mateus R Amorim, David Mendelowitz, Vsevolod Y Polotsk. Revisiting the Role of Serotonin in Sleep-Disordered Breathing. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338762. 5-ht acts on 5-ht receptor subtypes that modulate neural control of breathing and upper airway patency. 2024-02-10 2024-02-12 Not clear
Chiara Elli, Alessio Novella, Luca Pasin. Serotonin syndrome: A pharmacovigilance comparative study of drugs affecting serotonin levels. European journal of clinical pharmacology. vol 80. issue 2. 2024-02-06. PMID:38032391. serotonin syndrome is a rare and potentially fatal adverse drug reaction caused by serotonergic drugs and is due to an increase in serotonin concentration or activation of the 5-ht receptor in the central nervous system. 2024-02-06 2024-02-09 Not clear
Xia Wu, Ijaz Khan, Xiaoqi Ai, Jiliang Zhang, Haitao Shi, Ding Li, Meiling Hon. Effects of butyl paraben on behavior and molecular mechanism of Chinese striped-necked turtle (Mauremys sinensis). Aquatic toxicology (Amsterdam, Netherlands). vol 268. 2024-02-06. PMID:38320419. the analysis of neurotransmitter in the brain showed that 5-hydroxytryptamine (5-ht) contents in the groups of 500 and 5000 µg/l were significantly higher than the other groups, which was due to an increase in the mrna relative expression levels of the 5-ht receptor gene (5-htr), neurotransmitter transporter genes (drd4, slc6a4), and neurotransmitter synthase tryptophan hydroxylase (tph). 2024-02-06 2024-02-09 Not clear
Mengmeng Shi, Emmanuel J Rupia, Pengxin Jiang, Weiqun L. Switch from fight-flight to freeze-hide: The impacts of severe stress and brain serotonin on behavioral adaptations in flatfish. Fish physiology and biochemistry. 2024-02-03. PMID:38308734. we found that 5-ht suppression with 5-ht synthesis inhibitor p-chlorophenylalanine (pcpa) and 5-ht receptor subtype 1a (5-ht 2024-02-03 2024-02-06 Not clear
Giulia Radocchia, Massimiliano Marazzato, Karim Ben Harbi, Elena Capuzzo, Fabrizio Pantanella, Roberto De Giorgio, Matteo Guarino, Anna Costanzini, Letizia Zenzeri, Pasquale Parisi, Alessandro Ferretti, Enrico Felici, Anna Teresa Palamara, Giovanni Di Nardo, Serena Schipp. Chronic intestinal pseudo-obstruction: associations with gut microbiota and genes expression of intestinal serotonergic pathway. BMC microbiology. vol 24. issue 1. 2024-02-01. PMID:38302874. gut microbiota and its interplay with ens affect 5-ht synthesis, release, and the subsequent serotonin receptor activation. 2024-02-01 2024-02-04 Not clear
Sara Redenšek Trampuž, Sander van Riet, Åsa Nordling, Magnus Ingelman-Sundber. Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model. Scientific reports. vol 14. issue 1. 2024-01-16. PMID:38228622. treatment of the spheroids with 5-ht or free fatty acids (ffa) induced fibrosis, whereas treatment of the spheroids with the 5-ht receptor antagonists ketanserin, pimavanserin, sarpogrelate, and sb269970 inhibited ffa-induced fibrosis via a reduction in stellate cell activation as determined by the expression of vimentin, tgf-β1 and col1a1 production. 2024-01-16 2024-01-19 human
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzli. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT Journal of medicinal chemistry. 2024-01-08. PMID:38190615. first-in-class selenium-containing potent serotonin receptor 5-ht alzheimer's disease (ad) has a complex and not-fully-understood etiology. 2024-01-08 2024-01-10 Not clear
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzli. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT Journal of medicinal chemistry. 2024-01-08. PMID:38190615. recently, the serotonin receptor 5-ht 2024-01-08 2024-01-10 Not clear
Ivona Bečeheli, Marina Horvatiček, Maja Perić, Barbara Nikolić, Cyrielle Holuka, Marija Klasić, Marina Ivanišević, Mirta Starčević, Gernot Desoye, Dubravka Hranilović, Jonathan D Turner, Jasminka Šteful. Methylation of serotonin regulating genes in cord blood cells: association with maternal metabolic parameters and correlation with methylation in peripheral blood cells during childhood and adolescence. Clinical epigenetics. vol 16. issue 1. 2024-01-03. PMID:38172913. dna methylation plays a significant role in modulating the expression of genes responsible for maintaining 5-ht balance, such as 5-ht transporter (slc6a4), monoamine oxidase a (maoa), and 5-ht receptor type 2a (htr2a). 2024-01-03 2024-01-06 human
Jieling Cai, Jamie Cheung, Samson W M Cheung, Karie T C Chin, Ricky W K Leung, Ronald S T Lam, Rakesh Sharma, Jensen H C Yiu, Connie W Wo. Butyrate acts as a positive allosteric modulator of serotonin transporter to decrease ileal serotonin availability. British journal of pharmacology. 2023-12-22. PMID:38129963. the effectiveness of serotonin receptor blocker to treat radiation therapy-induced emesis suggests the pathophysiological role of serotonin. 2023-12-22 2023-12-24 Not clear
Marta Monteiro, Nuno C Pinheiro, Vikesh Samj. Serotonin Syndrome: An Emerging Reality in the Emergency Department. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021488. serotonin syndrome (ss) is an entity caused by interference with the serotonin metabolism and/or by medications that act as serotonin receptor agonists. 2023-12-01 2023-12-07 Not clear
Pareena Sharma, Reid W Collis, Julien Thoma. Serotonin Syndrome Triggered by an Interaction Between Opioid Analgesics and Cobicistat: A Challenging Diagnostic Case Report. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022058. serotonin syndrome is a clinically diagnosed disorder that may occur secondary to medications that increase the release of endogenous serotonin, impair the reuptake of serotonin from the synaptic cleft, are direct serotonin receptor agonists, or increase the sensitivity of the postsynaptic serotonin receptor. 2023-12-01 2023-12-07 Not clear
Marta Monteiro, Nuno C Pinheiro, Vikesh Samj. Serotonin Syndrome: An Emerging Reality in the Emergency Department. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021488. serotonin syndrome (ss) is an entity caused by interference with the serotonin metabolism and/or by medications that act as serotonin receptor agonists. 2023-11-29 2023-12-07 Not clear
Pareena Sharma, Reid W Collis, Julien Thoma. Serotonin Syndrome Triggered by an Interaction Between Opioid Analgesics and Cobicistat: A Challenging Diagnostic Case Report. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022058. serotonin syndrome is a clinically diagnosed disorder that may occur secondary to medications that increase the release of endogenous serotonin, impair the reuptake of serotonin from the synaptic cleft, are direct serotonin receptor agonists, or increase the sensitivity of the postsynaptic serotonin receptor. 2023-11-29 2023-12-07 Not clear
Elena V Mitroshina, Ekaterina A Marasanova, Maria V Vedunov. Functional Dimerization of Serotonin Receptors: Role in Health and Depressive Disorders. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003611. the objective of this review is to consolidate the current understanding of interactions within the 5-ht receptor family and between 5-ht receptors and members of other receptor families. 2023-11-25 2023-11-28 Not clear
Philip J Cowe. SSRIs in the Treatment of Depression: A Pharmacological CUL-DE-SAC? Current topics in behavioral neurosciences. 2023-11-03. PMID:37922101. attempts to supplement serotonin reuptake activity with actions at serotonin receptor sub-types have not yet yielded substantial benefits; however, vortioxetine may provide more utility in the management of cognitive impairment. 2023-11-03 2023-11-08 Not clear
Qiyi You, Qijun Li, Liyuan Lv, Zhihua Lin, Yinghui Dong, Hanhan Ya. Genome-Wide Identification of 5-HT Receptor Gene Family in Razor Clam Animals : an open access journal from MDPI. vol 13. issue 20. 2023-10-30. PMID:37893932. genome-wide identification of 5-ht receptor gene family in razor clam serotonin (5-ht) is primarily distributed in the gastrointestinal and central nervous systems, where it plays a crucial role in regulating various physiological functions such as digestion, reproduction and establishing animal emotions. 2023-10-30 2023-11-08 Not clear
Dhamyaa Abed Najm Al-Halboosi, Olena Savchenko, Lora K Heisler, Sergiy Sylantye. Modulation of GABA release by 5-HT Neuropharmacology. 2023-10-12. PMID:37827445. agonists of the 1b subtype of metabotropic serotonin receptor (5-ht 2023-10-12 2023-10-15 Not clear
Apeksha Parajulee, Kuglae Ki. Structural studies of serotonin receptor family. BMB reports. 2023-10-11. PMID:37817438. understanding the structure, functions and pharmacology of the serotonin receptor family is essential for unraveling the complexities of serotonin signaling and developing targeted therapeutics for neuropsychiatric disorders. 2023-10-11 2023-10-15 Not clear