| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matteo Spinelli, Salvatore Fusco, Marco Mainardi, Federico Scala, Francesca Natale, Rosita Lapenta, Andrea Mattera, Marco Rinaudo, Domenica Donatella Li Puma, Cristian Ripoli, Alfonso Grassi, Marcello D'Ascenzo, Claudio Grass. Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a. Nature communications. vol 8. issue 1. 2018-10-01. PMID:29222408. |
brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing glua1 palmitoylation through foxo3a. |
2018-10-01 |
2023-08-13 |
mouse |
| Matteo Spinelli, Salvatore Fusco, Marco Mainardi, Federico Scala, Francesca Natale, Rosita Lapenta, Andrea Mattera, Marco Rinaudo, Domenica Donatella Li Puma, Cristian Ripoli, Alfonso Grassi, Marcello D'Ascenzo, Claudio Grass. Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a. Nature communications. vol 8. issue 1. 2018-10-01. PMID:29222408. |
high-fat diet (hfd) and metabolic diseases cause detrimental effects on hippocampal synaptic plasticity, learning, and memory through molecular mechanisms still poorly understood. |
2018-10-01 |
2023-08-13 |
mouse |
| Εvgenia Dandi, Aikaterini Kalamari, Olga Touloumi, Rosa Lagoudaki, Evangelia Nousiopoulou, Constantina Simeonidou, Evangelia Spandou, Despina A Tat. Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 67. 2018-09-10. PMID:29545098. |
the aim of the present study was to investigate the mediated effects of environmental enrichment on postnatal stress-associated impact with regard to behavior, stress reactivity as well as synaptic plasticity changes in the dorsal hippocampus. |
2018-09-10 |
2023-08-13 |
rat |
| Vijayakumar Govindaraj, Radhika Nagamangalam Shridharan, Addicam Jagannadha Ra. Proteomic changes during adult stage in pre-optic, hypothalamus, hippocampus and pituitary regions of female rat brain following neonatal exposure to estradiol-17β. General and comparative endocrinology. vol 266. 2018-09-03. PMID:29777688. |
the differentially expressed proteins such as 14-3-3 zeta/delta (poa), lmna (hippocampus), axin2 (hypothalamus), syntaxin-7 (hippocampus), prolactin and somatotropin (pituitary) which have very important functions in the process of neuronal differentiation, migration, axon outgrowth, formation of dendritic spine density and synaptic plasticity and memory have not been previously reported in association with neonatal estrogen exposure. |
2018-09-03 |
2023-08-13 |
rat |
| Masoumeh Asadbegi, Alireza Komaki, Iraj Salehi, Parichehreh Yaghmaei, Azadeh Ebrahim-Habibi, Siamak Shahidi, Abdolrahman Sarihi, Sara Soleimani Asl, Zoleikha Golipoo. Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet. Brain research bulletin. vol 137. 2018-08-31. PMID:29339105. |
effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet. |
2018-08-31 |
2023-08-13 |
rat |
| Masoumeh Asadbegi, Alireza Komaki, Iraj Salehi, Parichehreh Yaghmaei, Azadeh Ebrahim-Habibi, Siamak Shahidi, Abdolrahman Sarihi, Sara Soleimani Asl, Zoleikha Golipoo. Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet. Brain research bulletin. vol 137. 2018-08-31. PMID:29339105. |
therefore, in the present study, we examined the protective and therapeutic effects of thy on amyloid-β (aβ)-induced impairments in the hippocampal synaptic plasticity of hfd-fed rats. |
2018-08-31 |
2023-08-13 |
rat |
| Dong-Ho You. Trigeminal long-term potentiation as a cellular substrate for migraine. Medical hypotheses. vol 110. 2018-08-27. PMID:29317063. |
in addition, the plasticity of synaptic transmission between nuclei or subnuclei in the vsn, in particular, the vsp, can be a cellular model for migraine, in the same way as the hippocampal synaptic plasticity is a model for learning and memory. |
2018-08-27 |
2023-08-13 |
Not clear |
| Qing-Hua Ma, Liu-Fang Jiang, Jian-Liang Mao, Wen-Xin Xu, Min Huan. Vildagliptin prevents cognitive deficits and neuronal apoptosis in a rat model of Alzheimer's disease. Molecular medicine reports. vol 17. issue 3. 2018-08-15. PMID:29257340. |
these results indicate that vildagliptin administration exerts a protective effect against cognitive deficits by reducing tau phosphorylation and increasing the expression of proteins associated with synaptic plasticity in the hippocampus. |
2018-08-15 |
2023-08-13 |
rat |
| Vassilios Papaleonidopoulos, George Trompoukis, Andriana Koutsoumpa, Costas Papatheodoropoulo. A gradient of frequency-dependent synaptic properties along the longitudinal hippocampal axis. BMC neuroscience. vol 18. issue 1. 2018-08-13. PMID:29233091. |
short-term synaptic plasticity plays fundamental roles in information processing and may be importantly involved in diversifying the properties of local neuronal network along the hippocampus long axis. |
2018-08-13 |
2023-08-13 |
rat |
| Wei Wang, Tao Tan, Yanzhi Yu, Zhilin Huang, Yehong Du, Huili Han, Zhifang Don. Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression. Behavioural brain research. vol 339. 2018-08-07. PMID:29162383. |
our previous study has shown that pentobarbital causes memory deficits and impairs hippocampal synaptic plasticity. |
2018-08-07 |
2023-08-13 |
Not clear |
| Claudia G Willmes, Till G A Mack, Julia Ledderose, Dietmar Schmitz, Christian Wozny, Britta J Eickhol. Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin. Scientific reports. vol 7. 2018-08-02. PMID:28198431. |
electrophysiological recordings in acute hippocampal slices and primary hippocampal neuronal cultures showed that basal synaptic transmission, and both long-term and homeostatic synaptic plasticity were unchanged, suggesting that loss of dbn is not sufficient in inducing synapse dysfunction. |
2018-08-02 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
mice lacking the transcriptional regulator bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. |
2018-07-30 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
here, we used bhlhe40 null mice on a congenic c57bl6/j background (bhlhe40 ko) to investigate the impact of bhlhe40 on neuronal excitability and synaptic plasticity in the hippocampus. |
2018-07-30 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
however, significant reductions in long term potentiation and long term depression at ca1 synapses were observed in bhlhe40 ko mice, indicating impaired hippocampal synaptic plasticity. |
2018-07-30 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
behavioral testing for spatial learning and memory on the morris water maze (mwm) revealed that while bhlhe40 ko mice performed similarly to wt controls initially, when the hidden platform was moved to the opposite quadrant bhlhe40 ko mice showed impairments in relearning, consistent with decreased hippocampal synaptic plasticity. |
2018-07-30 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
to investigate possible mechanisms for increased neuronal excitability and decreased synaptic plasticity, a whole genome mrna expression profile of bhlhe40 ko hippocampus was performed followed by a chromatin immunoprecipitation sequencing (chip-seq) screen of the validated candidate genes for bhlhe40 protein-dna interactions consistent with transcriptional regulation. |
2018-07-30 |
2023-08-13 |
mouse |
| Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattso. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PloS one. vol 13. issue 5. 2018-07-30. PMID:29715265. |
together, these findings support a role for bhlhe40 in regulating neuronal excitability and synaptic plasticity in the hippocampus and that indirect regulation of ide transcription may be involved in these phenotypes. |
2018-07-30 |
2023-08-13 |
mouse |
| Thais Ceresér Vilela, Alexandre Pastoris Muller, Adriani Paganini Damiani, Tamires Pavei Macan, Sabrina da Silva, Paula Bortoluzzi Canteiro, Alisson de Sena Casagrande, Giulia Dos Santos Pedroso, Renata Tiscoski Nesi, Vanessa Moraes de Andrade, Ricardo Aurino de Pinh. Strength and Aerobic Exercises Improve Spatial Memory in Aging Rats Through Stimulating Distinct Neuroplasticity Mechanisms. Molecular neurobiology. vol 54. issue 10. 2018-07-27. PMID:27878552. |
remarkably, the improvement in spatial memory was accompanied by an increase in synaptic plasticity proteins within the hippocampus after exercise training, with some differences in the intracellular functions of those proteins between the two exercise protocols. |
2018-07-27 |
2023-08-13 |
rat |
| Kelsey E McLimans, Joseph L Webb, Vellareddy Anantharam, Anumantha Kanthasamy, Auriel A Willett. Peripheral versus Central Index of Metabolic Dysfunction and Associations with Clinical and Pathological Outcomes in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue 4. 2018-07-23. PMID:28968233. |
insulin-like growth factor binding protein 2 (igfbp-2) regulates blood glucose levels, facilitates hippocampal synaptic plasticity and may have a predictive value for alzheimer's disease (ad) diagnosis. |
2018-07-23 |
2023-08-13 |
Not clear |
| Benoît Silvestre de Ferron, Catherine Vilpoux, Myriam Kervern, Alexandre Robert, Johan Antol, Mickael Naassila, Olivier Pierrefich. Increase of KCC2 in hippocampal synaptic plasticity disturbances after perinatal ethanol exposure. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27778437. |
increase of kcc2 in hippocampal synaptic plasticity disturbances after perinatal ethanol exposure. |
2018-07-16 |
2023-08-13 |
rat |