| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Ryoul Yang, Seungju Song, Hongik Hwang, Jung Hoon Jung, Su-Jeong Kim, Sora Yoon, Jin-Hoe Hur, Jae-Il Park, Cheol Lee, Dougu Nam, Young-Kyo Seo, Joung-Hun Kim, Hyewhon Rhim, Pann-Ghill Su. Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation. Scientific reports. vol 7. 2018-11-14. PMID:28368052. |
memory and synaptic plasticity are impaired by dysregulated hippocampal o-glcnacylation. |
2018-11-14 |
2023-08-13 |
Not clear |
| Haiying Gao, Lingyu Zhang, Zhenyi Chen, Shuncui Liu, Qinghong Zhang, Bingxi Zhan. Effects of intravenous anesthetics on the phosphorylation of cAMP response element‑binding protein in hippocampal slices of adult mice. Molecular medicine reports. vol 18. issue 1. 2018-11-13. PMID:29749444. |
camp response‑element binding protein (creb) functions in hippocampal synaptic plasticity and memory formation. |
2018-11-13 |
2023-08-13 |
mouse |
| Jihye Lee, Huiyoung Kwon, Jimin Yu, Eunbi Cho, Jieun Jeon, Seungheon Lee, Jong Hoon Ryu, Young Choon Lee, Dong Hyun Kim, Ji Wook Jun. The enhancing effect of Aubang Gahl Soo on the hippocampal synaptic plasticity and memory through enhancing cholinergic system in mice. Journal of ethnopharmacology. vol 224. 2018-11-13. PMID:29842961. |
the enhancing effect of aubang gahl soo on the hippocampal synaptic plasticity and memory through enhancing cholinergic system in mice. |
2018-11-13 |
2023-08-13 |
mouse |
| Di Yun, Yinghan Zhuang, Michael R Kreutz, Thomas Behnisc. The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. Neuropharmacology. vol 133. 2018-11-05. PMID:29407217. |
the role of 19s proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. |
2018-11-05 |
2023-08-13 |
mouse |
| Di Yun, Yinghan Zhuang, Michael R Kreutz, Thomas Behnisc. The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. Neuropharmacology. vol 133. 2018-11-05. PMID:29407217. |
however, their potential contribution to hippocampal synaptic plasticity has not been addressed in detail. |
2018-11-05 |
2023-08-13 |
mouse |
| Di Yun, Yinghan Zhuang, Michael R Kreutz, Thomas Behnisc. The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity. Neuropharmacology. vol 133. 2018-11-05. PMID:29407217. |
altogether, these results indicate an essential role of 19s proteasome associated dubs in regulating activity-dependent hippocampal synaptic plasticity. |
2018-11-05 |
2023-08-13 |
mouse |
| Paula Paci, Sylvain Gabriele, Laurence Ri. A new method allowing long-term potentiation recordings in hippocampal organotypic slices. Brain and behavior. vol 7. issue 5. 2018-11-02. PMID:28523233. |
hippocampal organotypic slices are used to improve the understanding of synaptic plasticity mechanisms because they allow longer term studies compared to acute slices. |
2018-11-02 |
2023-08-13 |
Not clear |
| Stine N Hansen, Jane M Bjørn Jørgensen, Jens R Nyengaard, Jens Lykkesfeldt, Pernille Tveden-Nybor. Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model. Nutrients. vol 10. issue 6. 2018-11-01. PMID:29890692. |
we hypothesized that vitc deficiency leads to decreased brain-derived neurotrophic factor and synaptic plasticity markers in selected brain areas (frontal cortex, hippocampus and striatum) and cause morphological changes in cornu ammonis 1 pyramidal neurons of the hippocampus either through a direct effect or indirectly by increased oxidative stress. |
2018-11-01 |
2023-08-13 |
Not clear |
| Fang Chen, Yingkun He, Pengwen Wang, Peng Wei, Huili Feng, Yingxue Rao, Jing Shi, Jinzhou Tia. Banxia Xiexin decoction ameliorated cognition via the regulation of insulin pathways and glucose transporters in the hippocampus of APPswe/PS1dE9 mice. International journal of immunopathology and pharmacology. vol 32. 2018-10-31. PMID:29873261. |
this research aimed to investigate the effects of banxia xiexin decoction (bxd) on cognitive deficits in appswe/ps1de9 double transgenic mice and verify the hypothesis that bxd treatment improves cognitive function via improving insulin signalling, glucose metabolism and synaptic plasticity in the hippocampus of appswe/ps1de9 double transgenic mice. |
2018-10-31 |
2023-08-13 |
mouse |
| Cailey Bromer, Thomas M Bartol, Jared B Bowden, Dusten D Hubbard, Dakota C Hanka, Paola V Gonzalez, Masaaki Kuwajima, John M Mendenhall, Patrick H Parker, Wickliffe C Abraham, Terrence J Sejnowski, Kristen M Harri. Long-term potentiation expands information content of hippocampal dentate gyrus synapses. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 10. 2018-10-30. PMID:29463730. |
an approach combining signal detection theory and precise 3d reconstructions from serial section electron microscopy (3dem) was used to investigate synaptic plasticity and information storage capacity at medial perforant path synapses in adult hippocampal dentate gyrus in vivo. |
2018-10-30 |
2023-08-13 |
Not clear |
| Cailey Bromer, Thomas M Bartol, Jared B Bowden, Dusten D Hubbard, Dakota C Hanka, Paola V Gonzalez, Masaaki Kuwajima, John M Mendenhall, Patrick H Parker, Wickliffe C Abraham, Terrence J Sejnowski, Kristen M Harri. Long-term potentiation expands information content of hippocampal dentate gyrus synapses. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 10. 2018-10-30. PMID:29463730. |
thus, synaptic plasticity altered total capacity, yet hippocampal subregions differed dramatically in their synaptic information storage capacity, reflecting their diverse functions and activation histories. |
2018-10-30 |
2023-08-13 |
Not clear |
| Jeehae Rhee, Kwanghoon Park, Ki Chan Kim, Chan Young Shin, ChiHye Chun. Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29696935. |
impaired hippocampal synaptic plasticity and enhanced excitatory transmission in a novel animal model of autism spectrum disorders with telomerase reverse transcriptase overexpression. |
2018-10-30 |
2023-08-13 |
mouse |
| Jeehae Rhee, Kwanghoon Park, Ki Chan Kim, Chan Young Shin, ChiHye Chun. Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29696935. |
we found that tert overexpression results in enhanced hippocampal excitation with no changes in inhibition and significantly impairs long-term synaptic plasticity. |
2018-10-30 |
2023-08-13 |
mouse |
| Md Mohibbullah, Jae-Suk Choi, Mohammad Maqueshudul Haque Bhuiyan, Md Nazmul Haque, Md Khalilur Rahman, Il Soo Moon, Yong-Ki Hon. The Red Alga Gracilariopsis chorda and Its Active Constituent Arachidonic Acid Promote Spine Dynamics via Dendritic Filopodia and Potentiate Functional Synaptic Plasticity in Hippocampal Neurons. Journal of medicinal food. vol 21. issue 5. 2018-10-29. PMID:29498567. |
the red alga gracilariopsis chorda and its active constituent arachidonic acid promote spine dynamics via dendritic filopodia and potentiate functional synaptic plasticity in hippocampal neurons. |
2018-10-29 |
2023-08-13 |
mouse |
| Aisa N Chepkova, Olga A Sergeeva, Boris Görg, Helmut L Haas, Nikolaj Klöcker, Dieter Häussinge. Impaired novelty acquisition and synaptic plasticity in congenital hyperammonemia caused by hepatic glutamine synthetase deficiency. Scientific reports. vol 7. 2018-10-18. PMID:28067279. |
we investigated alterations in behavior, synaptic plasticity and gene expression in the hippocampus and dorsal striatum of transgenic mice with systemic hyperammonemia resulting from conditional knockout of hepatic glutamine synthetase (lgs-ko). |
2018-10-18 |
2023-08-13 |
mouse |
| Aisa N Chepkova, Olga A Sergeeva, Boris Görg, Helmut L Haas, Nikolaj Klöcker, Dieter Häussinge. Impaired novelty acquisition and synaptic plasticity in congenital hyperammonemia caused by hepatic glutamine synthetase deficiency. Scientific reports. vol 7. 2018-10-18. PMID:28067279. |
thus, inborn systemic hyperammonemia resulted in significant deficits in novelty acquisition and disturbed synaptic plasticity in corticostriatal and hippocampal pathways involved in learning and goal-directed behavior. |
2018-10-18 |
2023-08-13 |
mouse |
| Nam-Kyung Yu, Heesoo Uhm, Jaehoon Shim, Jun-Hyeok Choi, Sangsu Bae, Todd Charlton Sacktor, Sungchul Hohng, Bong-Kiun Kaan. Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors. Molecular brain. vol 10. issue 1. 2018-10-16. PMID:29202853. |
in the current study, using a single-molecule live imaging technique, we report that the overexpression of pkmζ in hippocampal neurons immobilized glua2-containing ampars, highlighting a potential novel mechanism by which pkmζ may regulate memory and synaptic plasticity. |
2018-10-16 |
2023-08-13 |
Not clear |
| Yang Yao, Faqi Wang, Xuening Yang, Dawei Zang, Jiajia Yang, Zhiyun Wan. Bombesin attenuated ischemia-induced spatial cognitive and synaptic plasticity impairment associated with oxidative damage. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-15. PMID:29635132. |
however, the effects of grp agonist on spatial cognition and hippocampal synaptic plasticity are rarely investigated, especially in pathologic condition. |
2018-10-15 |
2023-08-13 |
rat |
| Yue Cao, Christian Hölscher, Meng-Ming Hu, Ting Wang, Fang Zhao, Yu Bai, Jun Zhang, Mei-Na Wu, Jin-Shun Q. DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease. European journal of pharmacology. vol 827. 2018-10-09. PMID:29551659. |
therefore, the neuroprotection of da5-ch in alleviating cognitive impairments and pathological damages might be associated with the improvement of hippocampal synaptic plasticity and activation of the pi3k/akt signaling pathway. |
2018-10-09 |
2023-08-13 |
mouse |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 and DPP-4 inhibitor equally prevents cognitive decline in obese rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-10-05. PMID:29793329. |
however, only fgf21 treatment led to significantly reduced body weight gain, visceral fat, systemic inflammation, improved hippocampal synaptic plasticity, enhanced fgf21 mediated signaling in the brain leading to prevention of early cognitive decline. |
2018-10-05 |
2023-08-13 |
human |