| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanghong Meng, Yu Zhang, Vitali Tregoubov, Douglas L Falls, Zhengping Ji. Regulation of spine morphology and synaptic function by LIMK and the actin cytoskeleton. Reviews in the neurosciences. vol 14. issue 3. 2003-10-23. PMID:14513866. |
using a combination of genetic manipulations and electrophysiological recordings in mice, we have demonstrated that limk-1 signaling is important in vivo in the regulation of the actin cytoskeleton, spine morphology, and synaptic function, including hippocampal long-term potentiation (ltp), a prominent form of long lasting synaptic plasticity thought to be critical to memory formation. |
2003-10-23 |
2023-08-12 |
mouse |
| Junfang Wu, Kuo-Ping Huang, Freesia L Huan. Participation of NMDA-mediated phosphorylation and oxidation of neurogranin in the regulation of Ca2+- and Ca2+/calmodulin-dependent neuronal signaling in the hippocampus. Journal of neurochemistry. vol 86. issue 6. 2003-10-17. PMID:12950461. |
these findings support the hypothesis that the derangement of hippocampal signal transduction cascades in ng ko mice causes the deficits in synaptic plasticity, learning and memory that occur in these mice. |
2003-10-17 |
2023-08-12 |
mouse |
| Graham L Collingridge, John T R Isaa. Functional roles of protein interactions with AMPA and kainate receptors. Neuroscience research. vol 47. issue 1. 2003-10-15. PMID:12941441. |
we have studied the functional roles of the interactions of these proteins in regulating ampa receptor-mediated synaptic transmission and synaptic plasticity in the hippocampus. |
2003-10-15 |
2023-08-12 |
Not clear |
| N Z Gerges, A M Aleisa, K A Alkadh. Impaired long-term potentiation in obese zucker rats: possible involvement of presynaptic mechanism. Neuroscience. vol 120. issue 2. 2003-10-14. PMID:12890522. |
electrophysiological investigation of basal synaptic transmission and synaptic plasticity in the ca1 region of the hippocampus was carried out in anesthetized obese zucker rats (ozr). |
2003-10-14 |
2023-08-12 |
rat |
| Sonia Hennou, Akihiko Kato, Edith M Schneider, Kenneth Lundstrom, Beat H Gähwiler, Kaoru Inokuchi, Urs Gerber, Markus U Ehrengrube. Homer-1a/Vesl-1S enhances hippocampal synaptic transmission. The European journal of neuroscience. vol 18. issue 4. 2003-10-14. PMID:12925007. |
our results show that homer-1a potentiates synaptic ampa receptor function, supporting a critical role for homer-1a in hippocampal synaptic plasticity. |
2003-10-14 |
2023-08-12 |
rat |
| Martin Theis, Kausik Si, Eric R Kande. Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 16. 2003-10-03. PMID:12871996. |
increasing evidence also implicates cpeb proteins as being important in the hippocampus, where these proteins are thought to regulate local protein synthesis and synaptic plasticity. |
2003-10-03 |
2023-08-12 |
mouse |
| Thérèse M Ja. Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. Progress in neurobiology. vol 69. issue 6. 2003-10-01. PMID:12880632. |
it is only recently that a number of studies on synaptic plasticity in the hippocampus and other brain areas have considered that a heterosynaptic modulatory input could be recruited as well as the coincident firing of pre- and post-synaptic neurons. |
2003-10-01 |
2023-08-12 |
Not clear |
| Thérèse M Ja. Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. Progress in neurobiology. vol 69. issue 6. 2003-10-01. PMID:12880632. |
this review will focus on dopamine contribution to synaptic plasticity in different brain areas (hippocampus, striatum and prefrontal cortex) with, for each region, a few lines on the distribution of da projections and receptors. |
2003-10-01 |
2023-08-12 |
Not clear |
| Pamela C Hebbard, Rebecca R King, Charles W Malsbury, Carolyn W Harle. Two organizational effects of pubertal testosterone in male rats: transient social memory and a shift away from long-term potentiation following a tetanus in hippocampal CA1. Experimental neurology. vol 182. issue 2. 2003-09-16. PMID:12895458. |
earlier data suggest pubertal testosterone reduces adult hippocampal synaptic plasticity. |
2003-09-16 |
2023-08-12 |
rat |
| Chi-Shing Chan, Edwin J Weeber, Sindhu Kurup, J David Sweatt, Ronald L Davi. Integrin requirement for hippocampal synaptic plasticity and spatial memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 18. 2003-09-09. PMID:12904471. |
integrin requirement for hippocampal synaptic plasticity and spatial memory. |
2003-09-09 |
2023-08-12 |
mouse |
| S Blackshaw, M J L Eliasson, A Sawa, C C Watkins, D Krug, A Gupta, T Arai, R J Ferrante, S H Snyde. Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831857. |
species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity. |
2003-09-05 |
2023-08-12 |
mouse |
| Catherine A Leamey, Chrystal L Ho-Pao, Mriganka Su. Role of calcineurin in activity-dependent pattern formation in the dorsal lateral geniculate nucleus of the ferret. Journal of neurobiology. vol 56. issue 2. 2003-09-05. PMID:12838580. |
calcineurin is a calcium/calmodulin dependent serine, threonine protein phosphatase suggested to mediate nmda-receptor dependent synaptic plasticity in the hippocampus. |
2003-09-05 |
2023-08-12 |
Not clear |
| D A Richards, T V P Bliss, C D Richard. Differential modulation of NMDA-induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons. The European journal of neuroscience. vol 17. issue 11. 2003-09-04. PMID:12814365. |
therefore two substances implicated in synaptic plasticity (arachidonic acid and nitric oxide) differentially modulate nmda-mediated ca2+ entry into hippocampal neurons. |
2003-09-04 |
2023-08-12 |
Not clear |
| Kenneth D Harris, Jozsef Csicsvari, Hajime Hirase, George Dragoi, György Buzsák. Organization of cell assemblies in the hippocampus. Nature. vol 424. issue 6948. 2003-08-19. PMID:12891358. |
because this temporal window matches the membrane time constant of pyramidal neurons, the period of the hippocampal gamma oscillation and the time window for synaptic plasticity, we propose that cooperative activity at this timescale is optimal for information transmission and storage in cortical circuits. |
2003-08-19 |
2023-08-12 |
Not clear |
| Tomás R Guilarte, Jennifer L McGlotha. Selective decrease in NR1 subunit splice variant mRNA in the hippocampus of Pb2+-exposed rats: implications for synaptic targeting and cell surface expression of NMDAR complexes. Brain research. Molecular brain research. vol 113. issue 1-2. 2003-08-18. PMID:12750004. |
our present findings indicate that pb(2+)-induced changes in nr1 subunit splice variant mrna expression in the hippocampus may provide a mechanism by which pb(2+)-exposure can modify nmdar-mediated calcium signaling and influence the degree of synaptic plasticity. |
2003-08-18 |
2023-08-12 |
rat |
| Bo Yang, Takashi Sakurai, Toshihiro Takata, Koichi Yokon. Effects of lactate/pyruvate on synaptic plasticity in the hippocampal dentate gyrus. Neuroscience research. vol 46. issue 3. 2003-08-14. PMID:12804794. |
effects of lactate/pyruvate on synaptic plasticity in the hippocampal dentate gyrus. |
2003-08-14 |
2023-08-12 |
Not clear |
| John A Wemmie, Candice C Askwith, Ejvis Lamani, Martin D Cassell, John H Freeman, Michael J Wels. Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 13. 2003-08-14. PMID:12843249. |
the acid-sensing ion channel, asic1, contributes to synaptic plasticity in the hippocampus and to hippocampus-dependent spatial memory. |
2003-08-14 |
2023-08-12 |
mouse |
| Valentin Stein, David R C House, David S Bredt, Roger A Nicol. Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 13. 2003-08-14. PMID:12843250. |
to determine whether this effect is related to synaptic plasticity at these synapses, we examined whether psd-95 expression mimics long-term potentiation (ltp), and also whether it influences ltp and long-term depression (ltd) in hippocampal slice cultures. |
2003-08-14 |
2023-08-12 |
Not clear |
| Mariana Alonso, Monica R M Vianna, Ivan Izquierdo, Jorge H Medin. Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cellular and molecular neurobiology. vol 22. issue 5-6. 2003-08-13. PMID:12585686. |
given that brain-derived neutrophic factor (bdnf) modulates both short-term synaptic function and activity-dependent synaptic plasticity in the adult hippocampus, here we examined signaling mechanisms in vivo in the hippocampus mediating bdnf modulation of long-term memory (ltm) formation of a one-trial fear-motivated learning task in rats. |
2003-08-13 |
2023-08-12 |
human |
| Detlef Balschun, David P Wolfer, Peter Gass, Theo Mantamadiotis, Hans Welzl, Günther Schütz, Julietta U Frey, Hans-Peter Lip. Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 15. 2003-08-13. PMID:12867515. |
does camp response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory? |
2003-08-13 |
2023-08-12 |
mouse |