Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P V Nguyen, N H Wo. Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. Progress in neurobiology. vol 71. issue 6. 2004-04-15. PMID:15013227. |
protein kinases critically regulate synaptic plasticity in the mammalian hippocampus. |
2004-04-15 |
2023-08-12 |
Not clear |
P V Nguyen, N H Wo. Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. Progress in neurobiology. vol 71. issue 6. 2004-04-15. PMID:15013227. |
we review the roles of pka in activity-dependent forms of hippocampal synaptic plasticity by highlighting particular themes that have emerged in ongoing research. |
2004-04-15 |
2023-08-12 |
Not clear |
P V Nguyen, N H Wo. Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. Progress in neurobiology. vol 71. issue 6. 2004-04-15. PMID:15013227. |
we also discuss many of the substrates that have been implicated as targets for pka's actions in hippocampal synaptic plasticity, including creb, protein phosphatases, and glutamatergic receptors. |
2004-04-15 |
2023-08-12 |
Not clear |
A C Arai, Y-F Xia, E Suzuk. Modulation of AMPA receptor kinetics differentially influences synaptic plasticity in the hippocampus. Neuroscience. vol 123. issue 4. 2004-04-12. PMID:14751292. |
modulation of ampa receptor kinetics differentially influences synaptic plasticity in the hippocampus. |
2004-04-12 |
2023-08-12 |
Not clear |
A C Arai, Y-F Xia, E Suzuk. Modulation of AMPA receptor kinetics differentially influences synaptic plasticity in the hippocampus. Neuroscience. vol 123. issue 4. 2004-04-12. PMID:14751292. |
the present study examined three of these modulators for their effects on synaptic plasticity in field ca1 of hippocampal slices, two of them being the benzamide drugs 1-(quinoxalin-6-ylcarbonyl)piperidine (cx516) and 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (cx546) which prominently enhance synaptic transmission yet differ in their relative impact on amplitude versus duration of the synaptic response. |
2004-04-12 |
2023-08-12 |
Not clear |
A C Arai, Y-F Xia, E Suzuk. Modulation of AMPA receptor kinetics differentially influences synaptic plasticity in the hippocampus. Neuroscience. vol 123. issue 4. 2004-04-12. PMID:14751292. |
these results suggest that (1) modulation of ampa receptors which increases either response amplitude or duration can facilitate ltp formation, (2) modulators that effectively slow response deactivation augment the maximum magnitude of ltp and ltd, and (3) receptor desensitization may have a minor impact on synaptic plasticity in the hippocampus. |
2004-04-12 |
2023-08-12 |
Not clear |
Benedict C Albensi, Gabrielle Ata, Erin Schmidt, Joseph D Waterman, Damir Janigr. Activation of long-term synaptic plasticity causes suppression of epileptiform activity in rat hippocampal slices. Brain research. vol 998. issue 1. 2004-03-22. PMID:14725968. |
activation of long-term synaptic plasticity causes suppression of epileptiform activity in rat hippocampal slices. |
2004-03-22 |
2023-08-12 |
rat |
San Nan Yang, Li-Tung Huang, Chih-Lu Wang, Wu-Fu Chen, Chin-Hwa Yang, Shinn-Zong Lin, Min-Chi Lai, Shyi-Jao Chen, Pao-Luh Ta. Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring. Hippocampus. vol 13. issue 8. 2004-03-12. PMID:14750654. |
collectively, the study suggests that maternal exposure to morphine reduces the range of synaptic plasticity by decreasing the expression of ltd, but not of ltp, in ca1 pyramidal neurons of the hippocampus from rat offspring. |
2004-03-12 |
2023-08-12 |
rat |
M L Hayward, A E Martin, J F Brien, H C Dringenberg, M C Olmstead, J N Reynold. Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14600252. |
increased activity-dependent potentiation of gaba release in the hippocampus may contribute to alterations in synaptic plasticity observed in cpee offspring. |
2004-03-11 |
2023-08-12 |
Not clear |
Hu Zhao, Hong Xu, Xiaohu X. Effects of naloxone on the long-term potentiation of EPSPs from the pathway of Schaffer collateral to CA1 region of hippocampus in aged rats with declined memory. Brain research. vol 996. issue 1. 2004-03-01. PMID:14670637. |
morris water maze (mwm) was employed to distinguish the aged rats with declined memory to investigate the effect of naloxone on the synaptic plasticity of hippocampus in declined memory aged rats. |
2004-03-01 |
2023-08-12 |
rat |
Hu Zhao, Hong Xu, Xiaohu X. Effects of naloxone on the long-term potentiation of EPSPs from the pathway of Schaffer collateral to CA1 region of hippocampus in aged rats with declined memory. Brain research. vol 996. issue 1. 2004-03-01. PMID:14670637. |
it is suggested that naloxone can improve learning and memory through enhancement of the synaptic plasticity of hippocampus in aged rats with declined memory. |
2004-03-01 |
2023-08-12 |
rat |
Yan-You Huang, Christopher Pittenger, Eric R Kande. A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 3. 2004-03-01. PMID:14711997. |
a form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. |
2004-03-01 |
2023-08-12 |
mouse |
Yan-You Huang, Christopher Pittenger, Eric R Kande. A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 3. 2004-03-01. PMID:14711997. |
the late, transcription- and translation-dependent phase of long-term synaptic potentiation (l-ltp) at the schaffer collateral synapse of the hippocampus is an experimental model of the synaptic plasticity underlying long-lasting memory formation. |
2004-03-01 |
2023-08-12 |
mouse |
Robert C Malenk. Synaptic plasticity and AMPA receptor trafficking. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684431. |
the best-characterized forms of such synaptic plasticity are the long-term depression (ltd) and long-term potentiation (ltp) observed at excitatory synapses in the ca1 region of the hippocampus. |
2004-02-13 |
2023-08-12 |
Not clear |
Feng Wang, Nobuya Matsuoka, Seitaro Mutoh, Shuji Kanek. Modulation of Ca2+ channel currents by a novel antidementia drug N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate (FK960) in rat hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 308. issue 1. 2004-02-11. PMID:14569070. |
together, these mechanisms may be involved in the selective effects of fk960 on somatostatin release, excitatory transmission, and synaptic plasticity in the hippocampus. |
2004-02-11 |
2023-08-12 |
rat |
Kimberly A Moore, Roger A Nicoll, Dietmar Schmit. Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 24. 2004-02-02. PMID:14608033. |
adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. |
2004-02-02 |
2023-08-12 |
Not clear |
M E Gilber. Perinatal exposure to polychlorinated biphenyls alters excitatory synaptic transmission and short-term plasticity in the hippocampus of the adult rat. Neurotoxicology. vol 24. issue 6. 2004-01-30. PMID:14637380. |
thus, in addition to impairment in use-dependent synaptic plasticity reported previously, the present report reveals that basic components of information processing within the hippocampus are permanently altered as a result of perinatal exposure to pcbs. |
2004-01-30 |
2023-08-12 |
rat |
Ekrem Dere, Maria A De Souza-Silva, Bianca Topic, Richard E Spieler, Helmut L Haas, Joseph P Husto. Histidine-decarboxylase knockout mice show deficient nonreinforced episodic object memory, improved negatively reinforced water-maze performance, and increased neo- and ventro-striatal dopamine turnover. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 6. 2004-01-30. PMID:14657262. |
the brain's histaminergic system has been implicated in hippocampal synaptic plasticity, learning, and memory, as well as brain reward and reinforcement. |
2004-01-30 |
2023-08-12 |
mouse |
Alexander Kolleker, J Julius Zhu, Bettina J Schupp, Yi Qin, Volker Mack, Thilo Borchardt, Georg Köhr, Roberto Malinow, Peter H Seeburg, Pavel Oste. Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors. Neuron. vol 40. issue 6. 2004-01-28. PMID:14687553. |
trafficking of glur-b(long)-containing receptors thus mediates a glur-a-independent form of glutamatergic synaptic plasticity in the juvenile hippocampus. |
2004-01-28 |
2023-08-12 |
Not clear |
Sandrine Hugues, Karima Kessal, Mark J Hunt, Rene Garci. A conditioned stressful environment causes short-term metaplastic-like changes in the rat nucleus accumbens. Journal of neurophysiology. vol 90. issue 5. 2004-01-22. PMID:14615430. |
stress-related alterations to the induction of hippocampal synaptic plasticity have been implicated in certain forms of psychiatric disorders. |
2004-01-22 |
2023-08-12 |
rat |