| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling Chen, Kiyofumi Yamada, Toshitaka Nabeshima, Masahiro Sokab. alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats. Neuropharmacology. vol 50. issue 2. 2006-04-12. PMID:16324726. |
here, using a real-time optical recording technique, we demonstrate that basal synaptic transmission and several forms of synaptic plasticity, including long-term potentiation (ltp), post-tetanic potentiation (ptp) and paired-pulse facilitation (ppf) are deficient at the schaffer collateral-ca1 synapse in hippocampal slices from abeta-infused brain. |
2006-04-12 |
2023-08-12 |
rat |
| Evelin L Schaeffer, Wagner F Gatta. Inhibition of calcium-independent phospholipase A2 activity in rat hippocampus impairs acquisition of short- and long-term memory. Psychopharmacology. vol 181. issue 2. 2006-04-10. PMID:15830227. |
in rat hippocampal slices, both intracellular cytosolic ca(2+)-dependent pla(2) (cpla(2)) and ca(2+)-independent pla(2) (ipla(2)) have been implicated in mechanisms of synaptic plasticity underlying memory processes. |
2006-04-10 |
2023-08-12 |
mouse |
| Alain Artola, Josefien C von Frijtag, Patrick C J Fermont, Willem Hendrik Gispen, Loes H Schrama, Amer Kamal, Berry M Spruij. Long-lasting modulation of the induction of LTD and LTP in rat hippocampal CA1 by behavioural stress and environmental enrichment. The European journal of neuroscience. vol 23. issue 1. 2006-04-06. PMID:16420435. |
because activity-dependent persistent changes in synaptic strength are believed to mediate memory processes in brain areas such as hippocampus, we tested whether behaviour has also long-lasting effects on synaptic plasticity by examining the induction of long-term potentiation (ltp) and long-term depression (ltd) in slices of hippocampal ca1 obtained from rats either 7-9 months after social defeat (behavioural stress) or 3-5 weeks after 5-week exposure to environmental enrichment. |
2006-04-06 |
2023-08-12 |
rat |
| Chie Harashima, David M Jacobowitz, Jassir Witta, Rosemary C Borke, Tyler K Best, Richard J Siarey, Zygmunt Galdzick. Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome. The Journal of comparative neurology. vol 494. issue 5. 2006-04-04. PMID:16374808. |
ts65dn, a mouse model of down syndrome (ds), demonstrates abnormal hippocampal synaptic plasticity and behavioral abnormalities related to spatial learning and memory. |
2006-04-04 |
2023-08-12 |
mouse |
| Chi-Shing Chan, Edwin J Weeber, Lin Zong, Elaine Fuchs, J David Sweatt, Ronald L Davi. Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399691. |
beta 1-integrins are required for hippocampal ampa receptor-dependent synaptic transmission, synaptic plasticity, and working memory. |
2006-03-31 |
2023-08-12 |
mouse |
| G M Rune, M Frotsche. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience. vol 136. issue 3. 2006-03-30. PMID:16344155. |
neurosteroid synthesis in the hippocampus: role in synaptic plasticity. |
2006-03-30 |
2023-08-12 |
Not clear |
| G M Rune, M Frotsche. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience. vol 136. issue 3. 2006-03-30. PMID:16344155. |
we recently showed, for the first time, that estrogens are synthesized de novo in hippocampal neurons and that these hippocampus-derived estrogens are essential for synaptic plasticity. |
2006-03-30 |
2023-08-12 |
Not clear |
| G M Rune, M Frotsche. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience. vol 136. issue 3. 2006-03-30. PMID:16344155. |
our data provide strong evidence for estrogens being potent modulators of structural synaptic plasticity and point to a paracrine rather than endocrine mechanism of estrogen action in the hippocampus. |
2006-03-30 |
2023-08-12 |
Not clear |
| Ouissame Mnie-Filali, Mostafa El Mansari, Agnès Espana, Connie Sànchez, Nasser Haddjer. Allosteric modulation of the effects of the 5-HT reuptake inhibitor escitalopram on the rat hippocampal synaptic plasticity. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16330146. |
allosteric modulation of the effects of the 5-ht reuptake inhibitor escitalopram on the rat hippocampal synaptic plasticity. |
2006-03-29 |
2023-08-12 |
rat |
| Adele P Chen, Masuo Ohno, K Peter Giese, Ralf Kühn, Rachel L Chen, Alcino J Silv. Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory. Journal of neuroscience research. vol 83. issue 1. 2006-03-29. PMID:16342120. |
our findings demonstrate that b-raf plays a role in hippocampal erk activation, synaptic plasticity, and l&m. |
2006-03-29 |
2023-08-12 |
mouse |
| Irma E Holopaine. Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity. Neurochemical research. vol 30. issue 12. 2006-03-21. PMID:16362771. |
organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity. |
2006-03-21 |
2023-08-12 |
human |
| Y Izumi, K Nagashima, K Murayama, C F Zorumsk. Acute effects of ethanol on hippocampal long-term potentiation and long-term depression are mediated by different mechanisms. Neuroscience. vol 136. issue 2. 2006-03-17. PMID:16216426. |
to determine potential mechanisms contributing to ethanol-induced cognitive impairment, we examined acute effects of ethanol on hippocampal n-methyl-d-aspartate receptors and forms of synaptic plasticity thought to underlie memory processing. |
2006-03-17 |
2023-08-12 |
rat |
| C A Grillo, G G Piroli, G E Wood, L R Reznikov, B S McEwen, L P Reaga. Immunocytochemical analysis of synaptic proteins provides new insights into diabetes-mediated plasticity in the rat hippocampus. Neuroscience. vol 136. issue 2. 2006-03-17. PMID:16226381. |
accordingly, the aim of this study was to identify markers of synaptic plasticity using rapid and reliable techniques such as radioimmunocytochemistry and confocal microscopy, thereby providing a "birds-eye view" of the whole hippocampus under hypercorticosteronemic conditions. |
2006-03-17 |
2023-08-12 |
rat |
| C A Grillo, G G Piroli, G E Wood, L R Reznikov, B S McEwen, L P Reaga. Immunocytochemical analysis of synaptic proteins provides new insights into diabetes-mediated plasticity in the rat hippocampus. Neuroscience. vol 136. issue 2. 2006-03-17. PMID:16226381. |
collectively, these results demonstrate that changes in the expression and distribution of synaptic proteins provide another measure of synaptic plasticity in the rat hippocampus in response to glucocorticoid exposure, changes that may accompany or contribute to neuroanatomical, neurochemical, and behavioral changes observed in experimental models of type 1 diabetes. |
2006-03-17 |
2023-08-12 |
rat |
| Chu Chen, Mattie Hardy, Jian Zhang, Gerald J LaHoste, Nicolas G Baza. Altered NMDA receptor trafficking contributes to sleep deprivation-induced hippocampal synaptic and cognitive impairments. Biochemical and biophysical research communications. vol 340. issue 2. 2006-03-17. PMID:16376302. |
the results suggest that the reduction of functional nmdar in hippocampal neurons may underlie the sd-induced deficits in hippocampus-dependent contextual memory and long-term synaptic plasticity. |
2006-03-17 |
2023-08-12 |
mouse |
| Jessica L Banko, Francis Poulin, Lingfei Hou, Christine T DeMaria, Nahum Sonenberg, Eric Klan. The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 42. 2006-03-15. PMID:16237163. |
the translation repressor 4e-bp2 is critical for eif4f complex formation, synaptic plasticity, and memory in the hippocampus. |
2006-03-15 |
2023-08-12 |
mouse |
| Maria Kukley, Maximilian Schwan, Bertil B Fredholm, Dirk Dietric. The role of extracellular adenosine in regulating mossy fiber synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 11. 2006-03-13. PMID:15772343. |
in this study, we reassessed the role of ambient adenosine in regulating mossy fiber synaptic plasticity in mouse and rat hippocampal slices. |
2006-03-13 |
2023-08-12 |
mouse |
| Kristen L Brunson, Enikö Kramár, Bin Lin, Yuncai Chen, Laura Lee Colgin, Theodore K Yanagihara, Gary Lynch, Tallie Z Bara. Mechanisms of late-onset cognitive decline after early-life stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 41. 2006-03-13. PMID:16221841. |
here, we demonstrate that a period of early-life "psychological" stress causes late-onset, selective deterioration of both complex behavior and synaptic plasticity: two forms of memory involving the hippocampus, were severely but selectively impaired in middle-aged, but not young adult, rats exposed to fragmented maternal care during the early postnatal period. |
2006-03-13 |
2023-08-12 |
rat |
| Amor Belmeguenai, Christian Hanse. A role for protein phosphatases 1, 2A, and 2B in cerebellar long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 46. 2006-03-10. PMID:16291950. |
at other types of synapses (e.g., in the hippocampus), bidirectional synaptic plasticity is under control of a kinase/phosphatase switch, with pkc and camkii (calcium/calmodulin-dependent kinase ii) activity promoting ltp induction and phosphatase activity promoting ltd induction. |
2006-03-10 |
2023-08-12 |
rat |
| Boyer D Winters, Timothy J Busse. Glutamate receptors in perirhinal cortex mediate encoding, retrieval, and consolidation of object recognition memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 17. 2006-03-09. PMID:15858050. |
these results further demonstrate the importance of perirhinal cortex for object recognition memory and suggest that, as in the hippocampus, ampa and nmda receptors mediate synaptic transmission and activity-dependent synaptic plasticity, respectively, in several stages of memory processing. |
2006-03-09 |
2023-08-12 |
human |