| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenneth J O'Riordan, I-Chia Huang, Marina Pizzi, PierFranco Spano, Flora Boroni, Regula Egli, Priyanka Desai, Olivia Fitch, Lauren Malone, Hyung Jin Ahn, Hsiou-Chi Liou, J David Sweatt, Jonathan M Levenso. Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 18. 2006-05-31. PMID:16672661. |
the observations of this deficit in hippocampal synaptic plasticity prompted us to further investigate long-term memory formation in c-rel(-/-) mice. |
2006-05-31 |
2023-08-12 |
mouse |
| V Cheli, M Adrover, C Blanco, C Ferrari, A Cornea, F Pitossi, A L Epstein, D Jerusalinsk. Knocking-down the NMDAR1 subunit in a limited amount of neurons in the rat hippocampus impairs learning. Journal of neurochemistry. vol 97 Suppl 1. 2006-05-23. PMID:16635252. |
perhaps neurons undergoing synaptic plasticity are more susceptible to nr1 knockdown, and hence nmdar are particularly required in those neurons undergoing synaptic plasticity during learning, or perhaps, and more likely, there is not a high level of redundancy in the hippocampal circuits involved, leading to the idea that a certain level of nr1 expression/availability appears necessary for memory formation in most of ca1 pyramidal neurons. |
2006-05-23 |
2023-08-12 |
rat |
| Ana Ledo, Rui M Barbosa, Greg A Gerhardt, Enrique Cadenas, João Laranjinh. Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 48. 2006-05-22. PMID:16293699. |
nitric oxide (*no) production in response to stimulation of the nmda glutamate receptor is implicated not only in the synaptic plasticity in hippocampus but may also participate in excitotoxic cell death. |
2006-05-22 |
2023-08-12 |
rat |
| H Mukai, N Takata, H-T Ishii, N Tanabe, Y Hojo, A Furukawa, T Kimoto, S Kawat. Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: synaptocrinology. Neuroscience. vol 138. issue 3. 2006-05-18. PMID:16310315. |
hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: synaptocrinology. |
2006-05-18 |
2023-08-12 |
rat |
| N J MacLusky, T Hajszan, J Prange-Kiel, C Lerant. Androgen modulation of hippocampal synaptic plasticity. Neuroscience. vol 138. issue 3. 2006-05-18. PMID:16488544. |
androgen modulation of hippocampal synaptic plasticity. |
2006-05-18 |
2023-08-12 |
rat |
| Maria V Tejada-Simon, Laura E Villasana, Faridis Serrano, Eric Klan. NMDA receptor activation induces translocation and activation of Rac in mouse hippocampal area CA1. Biochemical and biophysical research communications. vol 343. issue 2. 2006-05-16. PMID:16546126. |
taken together, our data are consistent with the idea that rac could be participating in nmda receptor-dependent changes in morphology that occur during synaptic plasticity and memory formation in the adult mouse hippocampus. |
2006-05-16 |
2023-08-12 |
mouse |
| Fiona M Laird, Huaibin Cai, Alena V Savonenko, Mohamed H Farah, Kaiwen He, Tatyana Melnikova, Hongjin Wen, Hsueh-Cheng Chiang, Guilian Xu, Vassilis E Koliatsos, David R Borchelt, Donald L Price, Hey-Kyoung Lee, Philip C Won. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 50. 2006-05-11. PMID:16354928. |
however, bace1 null mice manifest alterations in hippocampal synaptic plasticity as well as in performance on tests of cognition and emotion. |
2006-05-11 |
2023-08-12 |
mouse |
| Frank O Maher, Rachael M Clarke, Aine Kelly, Rachel E Nally, Marina A Lync. Interaction between interferon gamma and insulin-like growth factor-1 in hippocampus impacts on the ability of rats to sustain long-term potentiation. Journal of neurochemistry. vol 96. issue 6. 2006-05-10. PMID:16464236. |
il-1beta has a negative impact on synaptic plasticity and therefore an increased concentration of il-1beta, such as that in the hippocampus of the aged rat, is associated with a deficit in long-term potentiation (ltp). |
2006-05-10 |
2023-08-12 |
rat |
| Christian von der Brelie, Robert Waltereit, Lian Zhang, Heinz Beck, Timo Kirschstei. Impaired synaptic plasticity in a rat model of tuberous sclerosis. The European journal of neuroscience. vol 23. issue 3. 2006-05-09. PMID:16487150. |
we have used rats that are heterozygous for an autosomal-dominant germline mutation in the tsc2 gene (tsc2+/- rats) to examine the consequences of tsc2 mutations for hippocampal synaptic plasticity. |
2006-05-09 |
2023-08-12 |
rat |
| J Harvey, L J Shanley, D O'Malley, A J Irvin. Leptin: a potential cognitive enhancer? Biochemical Society transactions. vol 33. issue Pt 5. 2006-05-02. PMID:16246038. |
in the hippocampus, leptin is a potential cognitive enhancer as genetically obese rodents with dysfunctional leptin receptors display impairments in hippocampal synaptic plasticity. |
2006-05-02 |
2023-08-12 |
mouse |
| J Harvey, L J Shanley, D O'Malley, A J Irvin. Leptin: a potential cognitive enhancer? Biochemical Society transactions. vol 33. issue Pt 5. 2006-05-02. PMID:16246038. |
here, we review the data that leptin influences hippocampal synaptic plasticity via enhancing nmda (n-methyl-d-aspartate) receptor function. |
2006-05-02 |
2023-08-12 |
mouse |
| Bonnie R Fletcher, Michael E Calhoun, Peter R Rapp, Matthew L Shapir. Fornix lesions decouple the induction of hippocampal arc transcription from behavior but not plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 5. 2006-04-27. PMID:16452674. |
the results further imply that fornix lesions may impair memory in part by decoupling neuronal activity from signaling pathways required for long-lasting hippocampal synaptic plasticity. |
2006-04-27 |
2023-08-12 |
rat |
| Shaomin Li, Xuejun Tian, Dean M Hartley, Larry A Fei. Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 6. 2006-04-26. PMID:16467520. |
moreover, the postnatal appearance of ras-grf-dependent ltp and ltd coincides with the emergence of hippocampal-dependent behavior, implying that ras-grf proteins contribute to forms of synaptic plasticity that are required specifically for mature hippocampal function. |
2006-04-26 |
2023-08-12 |
mouse |
| Rebecca S Hammond, Chris T Bond, Timothy Strassmaier, Thu Jennifer Ngo-Anh, John P Adelman, James Maylie, Robert W Stackma. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 6. 2006-04-26. PMID:16467533. |
small-conductance ca2+-activated k+ channel type 2 (sk2) modulates hippocampal learning, memory, and synaptic plasticity. |
2006-04-26 |
2023-08-12 |
mouse |
| Rebecca S Hammond, Chris T Bond, Timothy Strassmaier, Thu Jennifer Ngo-Anh, John P Adelman, James Maylie, Robert W Stackma. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 6. 2006-04-26. PMID:16467533. |
blocking all sk channel subtypes with apamin facilitates the induction of hippocampal synaptic plasticity and enhances hippocampal learning. |
2006-04-26 |
2023-08-12 |
mouse |
| Rebecca S Hammond, Chris T Bond, Timothy Strassmaier, Thu Jennifer Ngo-Anh, John P Adelman, James Maylie, Robert W Stackma. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 6. 2006-04-26. PMID:16467533. |
to determine the specific influence of sk2 channels on hippocampal synaptic plasticity, learning, and memory, we used gene targeting through homologous recombination in embryonic stem cells to generate transgenic mice that overexpress sk2 subunits by 10-fold (sk2+/t). |
2006-04-26 |
2023-08-12 |
mouse |
| Rebecca S Hammond, Chris T Bond, Timothy Strassmaier, Thu Jennifer Ngo-Anh, John P Adelman, James Maylie, Robert W Stackma. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 6. 2006-04-26. PMID:16467533. |
we conclude that sk2 channels regulate hippocampal synaptic plasticity and play a critical role in modulating mechanisms of learning and memory. |
2006-04-26 |
2023-08-12 |
mouse |
| Jolanta Orzeł-Gryglewska, Edyta Jurkowlaniec, Weronika Trojnia. Microinjection of procaine and electrolytic lesion in the ventral tegmental area suppresses hippocampal theta rhythm in urethane-anesthetized rats. Brain research bulletin. vol 68. issue 5. 2006-04-20. PMID:16377435. |
in addition mesocortical dopamine was found to influence hippocampus-related memory and hippocampal synaptic plasticity, both being linked to the theta rhythm. |
2006-04-20 |
2023-08-12 |
rat |
| Annette Gärtner, Dorit G Polnau, Volker Staiger, Carla Sciarretta, Liliana Minichiello, Hans Thoenen, Tobias Bonhoeffer, Martin Kort. Hippocampal long-term potentiation is supported by presynaptic and postsynaptic tyrosine receptor kinase B-mediated phospholipase Cgamma signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 13. 2006-04-18. PMID:16571757. |
neurotrophins have been shown to play a critical role in activity-dependent synaptic plasticity such as long-term potentiation (ltp) in the hippocampus. |
2006-04-18 |
2023-08-12 |
mouse |
| Henry D I Abarbanel, Sachin S Talathi, Leif Gibb, M I Rabinovic. Synaptic plasticity with discrete state synapses. Physical review. E, Statistical, nonlinear, and soft matter physics. vol 72. issue 3 Pt 1. 2006-04-13. PMID:16241489. |
experimental observations on synaptic plasticity at individual glutamatergic synapses from the ca3 shaffer collateral pathway onto ca1 pyramidal cells in the hippocampus suggest that the transitions in synaptic strength occur among discrete levels at individual synapses [c. c. h. petersen, proc. |
2006-04-13 |
2023-08-12 |
Not clear |