| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guilherme M Gomes, Gerusa D Dalmolin, Marta do Nascimento Cordeiro, Marcus V Gomez, Juliano Ferreira, Maribel A Rubi. The selective A-type K+ current blocker Tx3-1 isolated from the Phoneutria nigriventer venom enhances memory of naïve and Aβ(25-35)-treated mice. Toxicon : official journal of the International Society on Toxinology. vol 76. 2014-08-21. PMID:23994427. |
in particular, a-type k(+) currents (ia) play a key role in hippocampal synaptic plasticity. |
2014-08-21 |
2023-08-12 |
mouse |
| Anissa Kempf, Bjoern Tews, Michael E Arzt, Oliver Weinmann, Franz J Obermair, Vincent Pernet, Marta Zagrebelsky, Andrea Delekate, Cristina Iobbi, Ajmal Zemmar, Zorica Ristic, Miriam Gullo, Peter Spies, Dana Dodd, Daniel Gygax, Martin Korte, Martin E Schwa. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS biology. vol 12. issue 1. 2014-08-21. PMID:24453941. |
blockade of s1pr2 strongly enhances long-term potentiation (ltp) in the hippocampus of wild-type but not nogo-a(-/-) mice, indicating a repressor function of the nogo-a/s1pr2 axis in synaptic plasticity. |
2014-08-21 |
2023-08-12 |
mouse |
| Jun Yang, Ming-Xing Li, Yi Luo, Tao Chen, Jing Liu, Peng Fang, Bo Jiang, Zhuang-Li Hu, You Jin, Jian-Guo Chen, Fang Wan. Chronic ceftriaxone treatment rescues hippocampal memory deficit in AQP4 knockout mice via activation of GLT-1. Neuropharmacology. vol 75. 2014-08-19. PMID:23973312. |
these results suggest that aqp4 functions as the modulator of synaptic plasticity and memory, and chronic cef treatment rescues hippocampal memory deficit induced by aqp4 knockout. |
2014-08-19 |
2023-08-12 |
mouse |
| Lorena S Navigatore-Fonzo, Silvia M Delgado, Maria Sofia Gimenez, Ana C Anzulovic. Daily rhythms of catalase and glutathione peroxidase expression and activity are endogenously driven in the hippocampus and are modified by a vitamin A-free diet. Nutritional neuroscience. vol 17. issue 1. 2014-08-15. PMID:23485553. |
alterations in enzymatic antioxidant defense systems lead to a deficit of cognitive functions and altered hippocampal synaptic plasticity. |
2014-08-15 |
2023-08-12 |
rat |
| Matthew J MacDougall, John G Howlan. Acute stress, but not corticosterone, disrupts short- and long-term synaptic plasticity in rat dorsal subiculum via glucocorticoid receptor activation. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 11. 2014-08-14. PMID:22918985. |
the subiculum (sub) serves as the major output structure of the hippocampus; therefore, exploring synaptic plasticity within this region is of great importance for understanding the dynamics of hippocampal circuitry and hippocampal-cortical interactions. |
2014-08-14 |
2023-08-12 |
rat |
| Matthew J MacDougall, John G Howlan. Acute stress, but not corticosterone, disrupts short- and long-term synaptic plasticity in rat dorsal subiculum via glucocorticoid receptor activation. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 11. 2014-08-14. PMID:22918985. |
previous research has shown exposure to acute stress dramatically alters synaptic plasticity within the hippocampus proper. |
2014-08-14 |
2023-08-12 |
rat |
| Matthew J MacDougall, John G Howlan. Acute stress, but not corticosterone, disrupts short- and long-term synaptic plasticity in rat dorsal subiculum via glucocorticoid receptor activation. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 11. 2014-08-14. PMID:22918985. |
using in vivo electrophysiological recordings in urethane-anesthetized adult male sprague-dawley rats, we tested the effects of either acute restraint stress (30 min) or corticosterone (cort) injections (3 mg/kg; s.c.) on short- and long-term forms of synaptic plasticity in the cornu ammonis 1-sub pathway. |
2014-08-14 |
2023-08-12 |
rat |
| Taesup Cho, Jae K Ryu, Changiz Taghibiglou, Yuan Ge, Allen W Chan, Lidong Liu, Jie Lu, James G McLarnon, Yu Tian Wan. Long-term potentiation promotes proliferation/survival and neuronal differentiation of neural stem/progenitor cells. PloS one. vol 8. issue 10. 2014-08-14. PMID:24146937. |
here, we examined if hippocampal long-term potentiation (ltp), one of the most well characterized forms of synaptic plasticity, promotes neurogenesis by facilitating proliferation/survival and neuronal differentiation of nscs. |
2014-08-14 |
2023-08-12 |
rat |
| Kodeeswaran Parameshwaran, Manal A Buabeid, Subhrajit Bhattacharya, Subramaniam Uthayathas, Thiruchelvam Kariharan, Muralikrishnan Dhanasekaran, Vishnu Suppiramania. Long term alterations in synaptic physiology, expression of β2 nicotinic receptors and ERK1/2 signaling in the hippocampus of rats with prenatal nicotine exposure. Neurobiology of learning and memory. vol 106. 2014-08-11. PMID:23871741. |
excitatory synaptic physiology was analyzed using electrophysiological methods to detect changes in synaptic plasticity, excitatory synaptic transmission and synaptic currents mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (ampars) in the hippocampus. |
2014-08-11 |
2023-08-12 |
rat |
| Tetsuya Kimura, Daniel J Whitcomb, Jihoon Jo, Philip Regan, Thomas Piers, Seonghoo Heo, Christopher Brown, Tsutomu Hashikawa, Miyuki Murayama, Heon Seok, Ioannis Sotiropoulos, Eunjoon Kim, Graham L Collingridge, Akihiko Takashima, Kwangwook Ch. Microtubule-associated protein tau is essential for long-term depression in the hippocampus. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298146. |
to investigate a possible synaptic function of tau, we studied synaptic plasticity in the hippocampus and found a selective deficit in long-term depression (ltd) in tau knockout mice in vivo and in vitro, an effect that was replicated by rnai knockdown of tau in vitro. |
2014-08-11 |
2023-08-12 |
mouse |
| Efrén Alvarez-Salvado, Vicente Pallarés, Andrea Moreno, Santiago Canal. Functional MRI of long-term potentiation: imaging network plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298154. |
combining high-resolution fmri and in vivo electrophysiology in rats, we have previously reported a functional remodelling of long-range hippocampal networks induced by long-term potentiation (ltp) of synaptic plasticity in the perforant pathway. |
2014-08-11 |
2023-08-12 |
rat |
| Daiju Morita, Jong Cheol Rah, John T R Isaa. Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298157. |
taken together with previous studies in hippocampus and in other brain regions, these findings suggest that a common mechanism for the expression of activity-dependent glutamatergic synaptic plasticity involves the regulation of glua2-subunit composition and highlights a critical role for silent synapses in this process. |
2014-08-11 |
2023-08-12 |
Not clear |
| Zsuzsa Penke, Elise Morice, Alexandra Veyrac, Alexandra Gros, Carine Chagneau, Pascale LeBlanc, Nathalie Samson, Karsten Baumgärtel, Isabelle M Mansuy, Sabrina Davis, Serge Laroch. Zif268/Egr1 gain of function facilitates hippocampal synaptic plasticity and long-term spatial recognition memory. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298160. |
zif268/egr1 gain of function facilitates hippocampal synaptic plasticity and long-term spatial recognition memory. |
2014-08-11 |
2023-08-12 |
mouse |
| Olivia A Shipton, Ole Paulse. GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298164. |
n-methyl-d-aspartate receptor (nmdar)-dependent synaptic plasticity is a strong candidate to mediate learning and memory processes that require the hippocampus. |
2014-08-11 |
2023-08-12 |
Not clear |
| Xiao-Min Li, Fan Su, Mu-Huo Ji, Guang-Fen Zhang, Li-Li Qiu, Min Jia, Jun Gao, Zhongcong Xie, Jian-Jun Yan. Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice. Anesthesiology. vol 121. issue 1. 2014-08-08. PMID:24589481. |
neuregulin 1 (nrg1)-erbb4 signaling plays a key role in the modulation of hippocampal synaptic plasticity through regulating the neurotransmission. |
2014-08-08 |
2023-08-12 |
mouse |
| Helen E Scharfman, Neil J MacLusk. Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23660230. |
differential regulation of bdnf, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. |
2014-08-06 |
2023-08-12 |
rat |
| Nan Lin, Xiao-dong Pan, Ai-qin Chen, Yuan-gui Zhu, Ming Wu, Jing Zhang, Xiao-chun Che. Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice. Behavioural brain research. vol 258. 2014-07-31. PMID:24140565. |
tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and nmda receptor dysfunction in samp8 mice. |
2014-07-31 |
2023-08-12 |
mouse |
| Bai-Yun Zeng, Sarah Salvage, Peter Jenne. Effect and mechanism of acupuncture on Alzheimer's disease. International review of neurobiology. vol 111. 2014-07-28. PMID:24215923. |
in alzheimer's animal models, acupuncture stimulation at acupoints enhances cholinergic neurotransmission, trophic factor releasing, reduces apoptotic and oxidative damages, improves synaptic plasticity and decreases the levels of aβ proteins in the hippocampus and relevant brain regions. |
2014-07-28 |
2023-08-12 |
human |
| Syed Nuruddin, Anette Krogenæs, Ola Brønstad Brynildsrud, Steven Verhaegen, Neil P Evans, Jane E Robinson, Ira Ronit Hebold Haraldsen, Erik Ropsta. Peri-pubertal gonadotropin-releasing hormone agonist treatment affects sex biased gene expression of amygdala in sheep. Psychoneuroendocrinology. vol 38. issue 12. 2014-07-21. PMID:24103890. |
using a sheep model, we have previously shown that peri-pubertal pharmacological blockade of gonadotropin releasing hormone (gnrh) receptors, results in exaggerated sex-differences in cognitive executive function and emotional control, as well as sex and hemisphere specific patterns of expression of hippocampal genes associated with synaptic plasticity and endocrine signaling. |
2014-07-21 |
2023-08-12 |
Not clear |
| Dan Lyu, Wenli Yu, Ning Tang, Ruirui Wang, Zhenyu Zhao, Fang Xie, Yongjin He, Hongyin Du, Jun Che. The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways. Molecular pain. vol 9. 2014-07-17. PMID:24313960. |
our previous work demonstrated that persistent peripheral nociception (ppn) leads to synaptic plasticity and functional changes in the rat hippocampus. |
2014-07-17 |
2023-08-12 |
rat |