| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miranda C Staples, Airee Kim, Chitra D Mandya. Dendritic remodeling of hippocampal neurons is associated with altered NMDA receptor expression in alcohol dependent rats. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25769285. |
for this study, we investigated seven weeks of cie-induced morphological changes (dendritic complexity and dendritic spine density) of dentate gyrus (dg) granule cell neurons, ca3, and ca1 pyramidal neurons and the associated alterations in biochemical markers of synaptic plasticity and toxicity (nmda receptors and psd-95) in the hippocampus in ethanol-experienced wistar rats 3h (cie) and 21days (protracted abstinence) after the last ethanol vapor exposure. |
2016-01-11 |
2023-08-13 |
rat |
| M Ghilan, B N Hryciw, P S Brocardo, C A Bostrom, J Gil-Mohapel, B R Christi. Enhanced corticosteroid signaling alters synaptic plasticity in the dentate gyrus in mice lacking the fragile X mental retardation protein. Neurobiology of disease. vol 77. 2016-01-06. PMID:25731748. |
these results suggest that a loss of fmpr results in enhanced gr signaling that may adversely affect nmdar dependent synaptic plasticity in the dg. |
2016-01-06 |
2023-08-13 |
mouse |
| Zhen Zhang, Wei Wang, Peng Zhong, Sarah J Liu, Jonathan Z Long, Li Zhao, Hai-Qing Gao, Benjamin F Cravatt, Qing-Song Li. Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25131612. |
we tested whether cus and chronic jzl184 treatments affected adult neurogenesis and synaptic plasticity in the dentate gyrus (dg) of mouse hippocampus. |
2015-08-11 |
2023-08-13 |
mouse |
| Zhen Zhang, Wei Wang, Peng Zhong, Sarah J Liu, Jonathan Z Long, Li Zhao, Hai-Qing Gao, Benjamin F Cravatt, Qing-Song Li. Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. Hippocampus. vol 25. issue 1. 2015-08-11. PMID:25131612. |
these results suggest that enhanced adult neurogenesis and long-term synaptic plasticity in the dg of the hippocampus might contribute to antidepressant- and anxiolytic-like behavioral effects of jzl184. |
2015-08-11 |
2023-08-13 |
mouse |
| C A Bostrom, N-M Majaess, K Morch, E White, B D Eadie, B R Christi. Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23968838. |
we report that a loss of fmrp leads to impairments in n-methyl-d-aspartate receptor (nmdar)-dependent synaptic plasticity in the dentate gyrus (dg), but not in the cornu ammonis area 1 (ca1) subregion of the hippocampus of adult mice. |
2015-04-06 |
2023-08-12 |
mouse |
| C A Bostrom, N-M Majaess, K Morch, E White, B D Eadie, B R Christi. Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23968838. |
importantly, we demonstrate that treatment with nmdar co-agonists (glycine or d-serine) independently rescue impairments in nmdar-dependent synaptic plasticity in the dg of the fragile x mental retardation 1 (fmr1) knockout mouse. |
2015-04-06 |
2023-08-12 |
mouse |
| J Gil-Mohapel, A K Titterness, A R Patten, S Taylor, A Ratzlaff, T Ratzlaff, J Helfer, B R Christi. Prenatal ethanol exposure differentially affects hippocampal neurogenesis in the adolescent and aged brain. Neuroscience. vol 273. 2015-02-09. PMID:24846617. |
the ca shows a more consistent loss in neuronal numbers, with different ethanol exposure paradigms, than the dg, which in contrast shows more pronounced and consistent deficits in synaptic plasticity. |
2015-02-09 |
2023-08-13 |
Not clear |
| L Kamali Dolatabadi, P Reis. Acute effect of cholecystokinin on short-term synaptic plasticity in the rat hippocampus. Research in pharmaceutical sciences. vol 9. issue 5. 2015-02-06. PMID:25657805. |
in this study we aimed to evaluate the acute effects of cck on short-term synaptic plasticity in the dentate gyrus (dg) of the rat hippocampus. |
2015-02-06 |
2023-08-13 |
rat |
| Valentina Pendolino, Vincenza Bagetta, Veronica Ghiglieri, Carmelo Sgobio, Emanuela Morelli, Silvia Poggini, Igor Branchi, Emanuele C Latagliata, Tiziana Pascucci, Stefano Puglisi-Allegra, Paolo Calabresi, Barbara Piccon. l-DOPA reverses the impairment of Dentate Gyrus LTD in experimental parkinsonism via β-adrenergic receptors. Experimental neurology. vol 261. 2014-12-17. PMID:25058044. |
our work provides new evidence on the role of catecholamines in dg synaptic plasticity and sheds light on the possible synaptic mechanisms underlying cognitive deficits in pd. |
2014-12-17 |
2023-08-13 |
human |
| Junsi Zhang, Yanna Li, Jing Xu, Zhou Yan. The role of N-methyl-D-aspartate receptor in Alzheimer's disease. Journal of the neurological sciences. vol 339. issue 1-2. 2014-12-08. PMID:24548486. |
the synaptic plasticity was measured by recording long-term potentiation (ltp) and depression (ltd) in the perforant path (pp) to dentate gyrus (dg) of hippocampus. |
2014-12-08 |
2023-08-12 |
rat |
| Ghasem Zarei, Parham Reisi, Hojjatallah Alaei, Shaghayegh Haghjooye Javanmar. Effects of amitriptyline and fluoxetine on synaptic plasticity in the dentate gyrus of hippocampal formation in rats. Advanced biomedical research. vol 3. 2014-10-22. PMID:25337529. |
therefore, the aim of this study was to investigate the effects of amitriptyline and fluoxetine on synaptic plasticity in the dentate gyrus (dg) of the hippocampal formation in rat. |
2014-10-22 |
2023-08-13 |
rat |
| Anna R Patten, Patricia S Brocardo, Claire Sakiyama, Ryan C Wortman, Athena Noonan, Joana Gil-Mohapel, Brian R Christi. Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23996467. |
previous studies from our laboratory have shown that prenatal ethanol exposure (pnee) causes a significant deficit in synaptic plasticity, namely long-term potentiation (ltp), in the dentate gyrus (dg) region of the hippocampus of male rats. |
2014-07-09 |
2023-08-12 |
rat |
| Seyed Asaad Karimi, Iraj Salehi, Alireza Komaki, Abdolrahman Sarihi, Mohammad Zarei, Siamak Shahid. Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study. Brain research. vol 1539. 2014-06-20. PMID:24095795. |
it was suggested that chronic hfd consumption can impair hippocampal ltp in the granular cells of the dg, and antioxidant supplementation reverses the impairment of synaptic plasticity induced in dg. |
2014-06-20 |
2023-08-12 |
rat |
| Liang Chen, Yanyan Miao, Lin Chen, Peipei Jin, Yingying Zha, Yuming Chai, Fang Zheng, Yunjiao Zhang, Wei Zhou, Jigui Zhang, Longping Wen, Ming Wan. The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots. Biomaterials. vol 34. issue 38. 2014-05-21. PMID:24094936. |
we have demonstrated that cdse/zns quantum dots (qds), which are widely applied in vitro for diagnostics and cellular imaging, can impair synaptic transmission and synaptic plasticity in the dentate gyrus (dg) area, but the mechanism is still unclear. |
2014-05-21 |
2023-08-12 |
Not clear |
| Ramamoorthy Rajkumar, Sana Suri, Hong Min Deng, Gavin Stewart Daw. Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to induce long-lasting potentiation in the rat hippocampus. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23520012. |
a priming-challenge schedule of nicotine treatment causes long-lasting potentiation (llp), a form of synaptic plasticity closely associated with the norepinephrine (ne) neurotransmitter system, at the medial perforant path (mpp)-dentate gyrus (dg) synapse in the rat hippocampus. |
2014-01-23 |
2023-08-12 |
rat |
| Seong S Shim, Michael D Hammonds, Ronald F Mervi. Four weeks lithium treatment alters neuronal dendrites in the rat hippocampus. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23331381. |
to determine whether lithium treatment alters structural synaptic plasticity, this study examined the effect of 4 wk lithium treatment on the amount and distribution of dendrites in the dentate gyrus (dg) and hippocampal area ca1 of young adult rats. |
2014-01-15 |
2023-08-12 |
human |
| Carmen Vivar, Michelle C Potter, Henriette van Praa. All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis. Current topics in behavioral neurosciences. vol 15. 2013-11-19. PMID:22847651. |
in this present chapter we will highlight the effects of physical activity on cognition in rodents, as well as on dentate gyrus (dg) neurogenesis, synaptic plasticity, spine density, neurotransmission and growth factors, in particular brain-derived nerve growth factor (bdnf). |
2013-11-19 |
2023-08-12 |
human |
| Angélica Zepeda, Andrea Aguilar-Arredondo, Gabriela Michel, Laura Elisa Ramos-Languren, Martha L Escobar, Clorinda Aria. Functional recovery of the dentate gyrus after a focal lesion is accompanied by structural reorganization in the adult rat. Brain structure & function. vol 218. issue 2. 2013-08-16. PMID:22481229. |
using a subepileptogenic injection of kainic acid (ka), we induced a focal lesion in the dg and assessed in time (1) the loss and recovery of dependent and non dependent dg cognitive functions, (2) the anatomical reorganization of the dg using a stereological probe and immunohistochemical markers for different neuronal maturation stages and, (3) synaptic plasticity as assessed through the induction of in vivo long-term potentiation (ltp) in the mossy fiber pathway (ca3-dg). |
2013-08-16 |
2023-08-12 |
rat |
| Angélica Zepeda, Andrea Aguilar-Arredondo, Gabriela Michel, Laura Elisa Ramos-Languren, Martha L Escobar, Clorinda Aria. Functional recovery of the dentate gyrus after a focal lesion is accompanied by structural reorganization in the adult rat. Brain structure & function. vol 218. issue 2. 2013-08-16. PMID:22481229. |
however, behavioral and synaptic plasticity expression occurs in a time dependent fashion and occurs along the morphological restoration of the dg. |
2013-08-16 |
2023-08-12 |
rat |
| Shirin Babri, Mohammad Amani, Gisou Mohaddes, Alireza Alihemmati, Hadi Ebrahim. Effect of Aggregated β-Amyloid (1-42) on Synaptic Plasticity of Hippocampal Dentate Gyrus Granule Cells in Vivo. BioImpacts : BI. vol 2. issue 4. 2013-05-17. PMID:23678459. |
the aim of this study was to evaluate the synaptic plasticity and electrophysiological function of granule cells in hippocampal dentate gyrus (dg) after intracerebroventricular (i.c.v.) |
2013-05-17 |
2023-08-12 |
Not clear |