| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kanzari, C Bourcier-Lucas, A Freyssin, D N Abrous, N Haddjeri, G Luca. Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:28485406. |
however, to date no relationship has been established between an increased dg synaptic plasticity, and rapid ad-like action. |
2019-03-12 |
2023-08-13 |
rat |
| Karim A Alkadh. Delayed effects of combined stress and Aβ infusion on L-LTP of the dentate gyrus: Prevention by nicotine. Neuroscience letters. vol 682. 2019-03-11. PMID:29883681. |
chronic stress is associated with heightened aβ buildup and acceleration of development of ad, however, stress alone has no significant effect on synaptic plasticity in the dentate gyrus (dg) area. |
2019-03-11 |
2023-08-13 |
rat |
| Karim A Alkadh. Delayed effects of combined stress and Aβ infusion on L-LTP of the dentate gyrus: Prevention by nicotine. Neuroscience letters. vol 682. 2019-03-11. PMID:29883681. |
to investigate the effect of stress and nicotine on synaptic plasticity in the relatively injury-resistant dg area, the present experiments analyzed the effect of chronic stress and the neuroprotective effect of nicotine on ltp in the dg area of a rat model of ad. |
2019-03-11 |
2023-08-13 |
rat |
| Bridget N Queenan, Raymond L Dunn, Victor R Santos, Yang Feng, Megan N Huizenga, Robert J Hammack, Stefano Vicini, Patrick A Forcelli, Daniel T S Pa. Kappa opioid receptors regulate hippocampal synaptic homeostasis and epileptogenesis. Epilepsia. vol 59. issue 1. 2018-09-14. PMID:29114861. |
homeostatic synaptic plasticity (hsp) serves as a gain control mechanism at central nervous system (cns) synapses, including those between the dentate gyrus (dg) and ca3. |
2018-09-14 |
2023-08-13 |
Not clear |
| Xiao-Yu Zheng, Qian-Quan Wan, Chuan-Yi Zheng, Hong-Long Zhou, Xing-Yu Dong, Qing-Shan Deng, Hui Yao, Qiang Fu, Mou Gao, Zhong-Jie Yan, Shan-Shan Wang, Yu You, Jun Lv, Xiang-Yu Wang, Ke-En Chen, Mao-Ying Zhang, Ru-Xiang X. Amniotic Mesenchymal Stem Cells Decrease Aβ Deposition and Improve Memory in APP/PS1 Transgenic Mice. Neurochemical research. vol 42. issue 8. 2018-04-19. PMID:28397068. |
furthermore, enhanced hippocampal neurogenesis in the subgranular zone (sgz) of the dentate gyrus (dg) and enhanced synaptic plasticity following ham-msc treatment could be another important factor in reversing the cognitive decline in app/ps1 mice. |
2018-04-19 |
2023-08-13 |
mouse |
| Alexander M Kleschevnikov, Jessica Yu, Jeesun Kim, Larisa V Lysenko, Zheng Zeng, Y Eugene Yu, William C Moble. Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. Neurobiology of disease. vol 103. 2018-03-02. PMID:28342823. |
in view of the ability of fluoxetine to suppress kir3.2 channels, we asked if fluoxetine-treated dg slices of ts65dn:kcnj6+++ mice would rescue synaptic plasticity. |
2018-03-02 |
2023-08-13 |
mouse |
| O Hadad-Ophir, Z Ardi, N Brande-Eilat, O Kehat, R Anunu, G Richter-Levi. Exposure to prolonged controllable or uncontrollable stress affects GABAergic function in sub-regions of the hippocampus and the amygdala. Neurobiology of learning and memory. vol 138. 2018-02-22. PMID:27321164. |
synaptic plasticity and inhibitory activity in the dorsal dg was further assessed by applying different stimulation protocols and measuring evoked field potentials in vivo. |
2018-02-22 |
2023-08-13 |
Not clear |
| Musaad A Alshammari, Tahani K Alshammari, Miroslav N Nenov, Federico Scala, Fernanda Laezz. Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. Molecular neurobiology. vol 53. issue 10. 2017-12-25. PMID:26687232. |
here, we provide evidence for a previously undescribed function of fibroblast growth factor 14 (fgf14), a brain disease-associated factor that controls neuronal excitability and synaptic plasticity, in regulating adult neurogenesis in the dentate gyrus (dg). |
2017-12-25 |
2023-08-13 |
Not clear |
| Hamid Gholami Pourbadie, Nima Naderi, Hadi Mirzapour Delavar, Mahshid Hosseinzadeh, Nasrin Mehranfard, Fariba Khodagholi, Mahyar Janahmadi, Fereshteh Motamed. Decrease of high voltage Ca European journal of pharmacology. vol 794. 2017-04-05. PMID:27889432. |
there are some evidences indicating abnormal neuronal excitability and impaired synaptic plasticity in the dentate gyrus (dg) of ad animal model. |
2017-04-05 |
2023-08-13 |
Not clear |
| Masanari Kanemitsu, Yukiko Fueta, Toru Ishidao, Shuji Aou, Hajime Hor. Development of a direct exposure system for studying the mechanisms of central neurotoxicity caused by volatile organic compounds. Industrial health. vol 54. issue 1. 2017-01-23. PMID:26320726. |
both 6.4 and 2.2 mm of 1-bp did not change the paired-pulse response, but fully suppressed long-term potentiation in the dentate gyrus (dg) of hippocampal slices obtained from rats, suggesting that 1-bp decreases synaptic plasticity in the dg at the concentrations tested. |
2017-01-23 |
2023-08-13 |
rat |
| Fan Hu, Meng-Meng Ge, Wei-Heng Che. Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats. Synapse (New York, N.Y.). vol 70. issue 3. 2016-10-17. PMID:26562488. |
lead exposure has been implicated in the impairment of synaptic plasticity in the hippocampal dentate gyrus (dg) areas of rats. |
2016-10-17 |
2023-08-13 |
rat |
| Iraj Salehi, Ruhollah Karamian, Alireza Komaki, Lida Tahmasebi, Masoumeh Taheri, Masoumeh Nazari, Siamak Shahidi, Abdolrahman Sarih. Effects of vitamin E on lead-induced impairments in hippocampal synaptic plasticity. Brain research. vol 1629. 2016-09-22. PMID:26462654. |
these findings suggest that ve via its antioxidant activity reverses pb-induced impairments of synaptic plasticity in the dg. |
2016-09-22 |
2023-08-13 |
rat |
| M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. |
transforming growth factor-β signaling through intracellular smad3 has been implicated in parkinson's disease (pd) and it fulfills an important role in the neurogenesis and synaptic plasticity that occurs in the adult dentate gyrus (dg). |
2016-08-22 |
2023-08-13 |
mouse |
| Davide Guerrieri, Henriette van Praa. Exercise-mimetic AICAR transiently benefits brain function. Oncotarget. vol 6. issue 21. 2016-05-20. PMID:26286955. |
at the time-points where we observed equivalent running- and aicar-induced muscle pampk levels (7 and 14 days), cell proliferation, synaptic plasticity and gene expression, as well as markers of oxidative stress and inflammation in the dentate gyrus (dg) of the hippocampus and lateral entorhinal cortex (lec) were evaluated. |
2016-05-20 |
2023-08-13 |
mouse |
| Ruhollah Karamian, Alireza Komaki, Iraj Salehi, Lida Tahmasebi, Hamidreza Komaki, Siamak Shahidi, Abdolrahman Sarih. Vitamin C reverses lead-induced deficits in hippocampal synaptic plasticity in rats. Brain research bulletin. vol 116. 2016-05-02. PMID:26004788. |
vitamin c ameliorated the pb-induced impairment of synaptic plasticity in the dg via antioxidant activity. |
2016-05-02 |
2023-08-13 |
rat |
| Timal S Kannangara, Brennan D Eadie, Crystal A Bostrom, Kristin Morch, Patricia S Brocardo, Brian R Christi. GluN2A-/- Mice Lack Bidirectional Synaptic Plasticity in the Dentate Gyrus and Perform Poorly on Spatial Pattern Separation Tasks. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 8. 2016-03-30. PMID:24554729. |
thus, our results establish the glun2a subunit as a significant contributor to both bidirectional synaptic plasticity and spatial pattern separation in the dg. |
2016-03-30 |
2023-08-12 |
mouse |
| Giulia Zanni, Kai Zhou, Ilse Riebe, Cuicui Xie, Changlian Zhu, Eric Hanse, Klas Blomgre. Irradiation of the Juvenile Brain Provokes a Shift from Long-Term Potentiation to Long-Term Depression. Developmental neuroscience. vol 37. issue 3. 2016-03-29. PMID:26043717. |
surprisingly, the induction of long-term synaptic plasticity in the dg by applying 4 trains of high-frequency stimulation provoked a shift from long-term potentiation (ltp) to long-term depression (ltd) in irradiated animals compared to sham controls. |
2016-03-29 |
2023-08-13 |
mouse |
| Somayeh Zargooshnia, Siamak Shahidi, Fatemeh Ghahremanitamadon, Ali Nikkhah, Mehdi Mehdizadeh, Sara Soleimani As. The protective effect of Borago Officinalis extract on amyloid β (25-35)-induced long term potentiation disruption in the dentate gyrus of male rats. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:25060965. |
this data suggest that aβ (25-35) can effectively inhibit ltp in the granular cells of the dg in hippocampus, and borage supplementation reverse the synaptic plasticity in dg following aβ treatment and that borage consumption may lead to an improvement of ad-induced cognitive dysfunction. |
2016-03-17 |
2023-08-13 |
rat |
| Niels Hansen, Denise Manahan-Vaugha. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 7. 2016-02-19. PMID:24464942. |
we explored whether synaptic plasticity in the dg is influenced by activation of the lc via electrical stimulation. |
2016-02-19 |
2023-08-12 |
rat |
| Niels Hansen, Denise Manahan-Vaugha. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 7. 2016-02-19. PMID:24464942. |
this suggests in turn that synaptic plasticity in the dg is tightly regulated by activity in the noradrenergic system. |
2016-02-19 |
2023-08-12 |
rat |