| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert J Wickham, Wojciech Solecki, Liza R Rathbun, Nichole M Neugebauer, Robert Mark Wightman, Nii A Add. Advances in studying phasic dopamine signaling in brain reward mechanisms. Frontiers in bioscience (Elite edition). vol 5. 2014-02-17. PMID:23747914. |
since its discovery as a neurotransmitter by carlsson and colleagues (1), dopamine (da) has emerged as an important mediator of reward processing. |
2014-02-17 |
2023-08-12 |
Not clear |
| Isabelle Boileau, Doris Payer, Bindiya Chugani, Daniela Lobo, Arian Behzadi, Pablo M Rusjan, Sylvain Houle, Alan A Wilson, Jerry Warsh, Stephen J Kish, Martin Zac. The D2/3 dopamine receptor in pathological gambling: a positron emission tomography study with [11C]-(+)-propyl-hexahydro-naphtho-oxazin and [11C]raclopride. Addiction (Abingdon, England). vol 108. issue 5. 2014-01-07. PMID:23167711. |
because dopamine (da), a neurotransmitter implicated in reward and reinforcement, is probably involved, we used positron emission tomography (pet) to test whether pg is associated with abnormalities in d2 and d3 receptor levels, as observed in sud. |
2014-01-07 |
2023-08-12 |
Not clear |
| Rachel Harrison, Julia J Rucklidge, Neville Blampie. Use of micronutrients attenuates cannabis and nicotine abuse as evidenced from a reversal design: a case study. Journal of psychoactive drugs. vol 45. issue 2. 2013-08-21. PMID:23909004. |
alternatively, they may directly impact on the brain reward circuitry believed to be involved in the expression of addictions, thereby providing the appropriate precursors and cofactors necessary for adequate neurotransmitter synthesis. |
2013-08-21 |
2023-08-12 |
human |
| Nicole K Speed, Heinrich J G Matthies, J Phillip Kennedy, Roxanne A Vaughan, Jonathan A Javitch, Scott J Russo, Craig W Lindsley, Kevin Niswender, Aurelio Gall. Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression. ACS chemical neuroscience. vol 1. issue 7. 2013-08-09. PMID:22778840. |
dopamine (da) is a neurotransmitter implicated in multiple functions, including movement, cognition, motivation, and reward. |
2013-08-09 |
2023-08-12 |
Not clear |
| Lauren A O'Connell, Miles R Fontenot, Hans A Hofman. Neurochemical profiling of dopaminergic neurons in the forebrain of a cichlid fish, Astatotilapia burtoni. Journal of chemical neuroanatomy. vol 47. 2013-08-09. PMID:23295359. |
across vertebrates, the mesolimbic reward system is a highly conserved neural network that serves to evaluate the salience of environmental stimuli, with dopamine as the neurotransmitter most relevant to its function. |
2013-08-09 |
2023-08-12 |
Not clear |
| Sarah J Baracz, Jennifer L Cornis. Oxytocin modulates dopamine-mediated reward in the rat subthalamic nucleus. Hormones and behavior. vol 63. issue 2. 2013-07-19. PMID:23238104. |
it is not yet known if dopamine, the neurotransmitter primarily responsible for reward signaling, is also involved in mediating reward-related activity in the sth. |
2013-07-19 |
2023-08-12 |
rat |
| Mahlet Mersha, Rosaria Formisano, Rochelle McDonald, Pratima Pandey, Nektarios Tavernarakis, Singh Harbinde. GPA-14, a Gα(i) subunit mediates dopaminergic behavioral plasticity in C. elegans. Behavioral and brain functions : BBF. vol 9. 2013-07-18. PMID:23607404. |
the neurotransmitter dopamine is implicated in modulating behaviors, such as cognition, reward and memory. |
2013-07-18 |
2023-08-12 |
caenorhabditis_elegans |
| B O'Neill, M R Tilley, H H G. Cocaine produces conditioned place aversion in mice with a cocaine-insensitive dopamine transporter. Genes, brain, and behavior. vol 12. issue 1. 2013-07-03. PMID:23083326. |
these results indicate that while inhibition of the dat is necessary for cocaine reward, other cocaine targets and neurotransmitter systems may mediate the aversive properties of cocaine. |
2013-07-03 |
2023-08-12 |
mouse |
| Natalie Rios Herr, Robert Mark Wightma. Improved techniques for examining rapid dopamine signaling with iontophoresis. Frontiers in bioscience (Elite edition). vol 5. 2013-06-05. PMID:23276986. |
dopamine is a neurotransmitter that is utilized in brain circuits associated with reward processing and motor activity. |
2013-06-05 |
2023-08-12 |
rat |
| Elizabeth E Van Voorhees, John T Mitchell, F Joseph McClernon, Jean C Beckham, Scott H Kollin. Sex, ADHD symptoms, and smoking outcomes: an integrative model. Medical hypotheses. vol 78. issue 5. 2012-08-09. PMID:22341778. |
specifically, nicotine appears to mitigate core adhd symptoms through interaction with the dopamine reward processing system, and ovarian hormones have been found to interact with nicotine within the dopamine reward processing system to affect neurotransmitter release and functioning. |
2012-08-09 |
2023-08-12 |
Not clear |
| Karolina P Skibicka, Caroline Hansson, Emil Egecioglu, Suzanne L Dickso. Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression. Addiction biology. vol 17. issue 1. 2012-05-14. PMID:21309956. |
we further investigated ghrelin's effects on key mesolimbic reward nodes, the ventral tegmental area (vta) and nucleus accumbens (nacc), by evaluating the effects of chronic central ghrelin treatment on the expression of genes encoding major reward neurotransmitter receptors, namely dopamine and acetylcholine. |
2012-05-14 |
2023-08-12 |
Not clear |
| Karolina P Skibicka, Suzanne L Dickso. Ghrelin and food reward: the story of potential underlying substrates. Peptides. vol 32. issue 11. 2012-04-16. PMID:21621573. |
particular attention is given to the potential neurocircuitry and neurotransmitter systems downstream of ghrelin's effects on food reward. |
2012-04-16 |
2023-08-12 |
Not clear |
| Han Gerrits, Nicole Ec Bakker, Cindy Jm van de Ven-de Laat, Freek Gm Bourgondien, Carolien Peddemors, Ralph Hgm Litjens, Han J Kok, Gerard Mt Vogel, Magda Am Krajnc-Franken, Jan A Gosse. Gender-specific increase of bone mass by CART peptide treatment is ovary-dependent. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 26. issue 12. 2012-03-13. PMID:21887702. |
cocaine- and amphetamine-regulated transcript (cart) has emerged as a neurotransmitter and hormone that has been implicated in many processes including food intake, maintenance of body weight, and reward, but also in the regulation of bone mass. |
2012-03-13 |
2023-08-12 |
mouse |
| Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
although the mesolimbic dopamine hypothesis is the most influential theory of nicotine reward and reinforcement, there has been a consensus that other neurotransmitter systems contribute to the addictive properties of nicotine as well. |
2012-01-18 |
2023-08-12 |
Not clear |
| W C Poller, R Bernard, C Derst, T Weiss, V I Madai, R W Ve. Lateral habenular neurons projecting to reward-processing monoaminergic nuclei express hyperpolarization-activated cyclic nucleotid-gated cation channels. Neuroscience. vol 193. 2012-01-18. PMID:21798320. |
both monoaminergic neurotransmitter systems play a central role in reward processing and reward-related decision-making. |
2012-01-18 |
2023-08-12 |
rat |
| Dianne P Figlewicz, Alfred J Sipol. Energy regulatory signals and food reward. Pharmacology, biochemistry, and behavior. vol 97. issue 1. 2011-09-15. PMID:20230849. |
specifically, insulin and leptin can decrease food reward behaviors and modulate the function of neurotransmitter systems and neural circuitry that mediate food reward, the midbrain dopamine (da) and opioidergic pathways. |
2011-09-15 |
2023-08-12 |
Not clear |
| Thomas J H Chen, Kenneth Blum, Amanda L C Chen, Abdalla Bowirrat, William B Downs, Margret A Madigan, Roger L Waite, John A Bailey, Mallory Kerner, Swetha Yeldandi, Neil Majmundar, John Giordano, Siohban Morse, David Miller, Frank Fornari, Eric R Braverma. Neurogenetics and clinical evidence for the putative activation of the brain reward circuitry by a neuroadaptagen: proposing an addiction candidate gene panel map. Journal of psychoactive drugs. vol 43. issue 2. 2011-09-07. PMID:21858957. |
this document presents evidence supporting the role of the kb220/kb220z neuroadaptagens consisting of amino-acid neurotransmitter precursors and enkephalinase-catecholamine-methyl-transferase (comt) inhibition therapy called neuroadaptagen amino acid therapy (naat) in brain reward function. |
2011-09-07 |
2023-08-12 |
Not clear |
| Styliani Vlachou, Sebastien Guery, Wolfgang Froestl, Deboshri Banerjee, Jessica Benedict, M G Finn, Athina Marko. Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats. Psychopharmacology. vol 215. issue 1. 2011-08-15. PMID:21181127. |
γ-aminobutyric acid (gaba) is the major inhibitory neurotransmitter in the brain and is implicated in the modulation of central reward processes. |
2011-08-15 |
2023-08-12 |
rat |
| David H Skuse, Louise Gallaghe. Genetic influences on social cognition. Pediatric research. vol 69. issue 5 Pt 2. 2011-07-22. PMID:21289535. |
the processes of social cognition are also supported by reward circuitry, underpinned by the dopaminergic neurotransmitter system. |
2011-07-22 |
2023-08-12 |
human |
| Yann L Strat, Nicolas Ramoz, Gunter Schumann, Philip Gorwoo. Molecular genetics of alcohol dependence and related endophenotypes. Current genomics. vol 9. issue 7. 2011-07-14. PMID:19506733. |
since dopamine is the main neurotransmitter in the reward circuit, genes involved in the dopaminergic pathway represent candidates of interest. |
2011-07-14 |
2023-08-12 |
Not clear |