| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M K Ho, R F Tyndal. Overview of the pharmacogenomics of cigarette smoking. The pharmacogenomics journal. vol 7. issue 2. 2007-06-20. PMID:17224913. |
much attention has focused on genes involved in the neurotransmitter pathways for the brain reward system and genes altering nicotine metabolism. |
2007-06-20 |
2023-08-12 |
Not clear |
| Brian A Baldo, Ann E Kelle. Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding. Psychopharmacology. vol 191. issue 3. 2007-06-12. PMID:17318502. |
in the present article, evidence is reviewed from studies of food intake, feeding microstructure, instrumental responding for food reinforcement, and dopamine efflux associated with feeding, which suggests that reward processing in the acb is best understood as an interaction among distinct processes coded by discrete neurotransmitter systems. |
2007-06-12 |
2023-08-12 |
Not clear |
| M S Mazei-Robinson, R D Blakel. ADHD and the dopamine transporter: are there reasons to pay attention? Handbook of experimental pharmacology. issue 175. 2007-05-23. PMID:16722244. |
the catecholamine dopamine (da) plays an important role as a neurotransmitter in the brain in circuits linked to motor function, reward, and cognition. |
2007-05-23 |
2023-08-12 |
mouse |
| Sarah E Zemor. Helping as healing among recovering alcoholics. Southern medical journal. vol 100. issue 4. 2007-05-08. PMID:17458422. |
a recent study found that, when women cooperated (versus competed) in a prisoner's dilemma game, blood flow increased in areas of their brains rich in dopamine, the neurotransmitter involved in reward systems and famed in part for its role in addictive behaviors. |
2007-05-08 |
2023-08-12 |
human |
| K D Alex, E A Pehe. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacology & therapeutics. vol 113. issue 2. 2007-04-19. PMID:17049611. |
the neurotransmitter dopamine (da) has a long association with normal functions such as motor control, cognition, and reward, as well as a number of syndromes including drug abuse, schizophrenia, and parkinson's disease. |
2007-04-19 |
2023-08-12 |
Not clear |
| Song Guo, Da Fang Chen, Dong Feng Zhou, Hong Qiang Sun, Gui Ying Wu, Colin N Haile, Therese A Kosten, Thomas R Kosten, Xiang Yang Zhan. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology. vol 190. issue 4. 2007-04-06. PMID:17206495. |
catechol-o-methyltransferase (comt) is an enzyme involved in the degradation and inactivation of the neurotransmitter dopamine, which is important in mediating drug reward such as nicotine in tobacco smoke. |
2007-04-06 |
2023-08-12 |
Not clear |
| George W Hubert, Michael J Kuha. Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens. Neuropeptides. vol 40. issue 6. 2007-01-18. PMID:17064765. |
cart peptide is a peptidergic neurotransmitter that is expressed in brain regions involved in critical biological processes such as feeding and stress, and in areas associated with drug reward and abuse including the dopamine-rich nucleus accumbens (nacc), which can be considered part of the basal ganglia. |
2007-01-18 |
2023-08-12 |
rat |
| B Lau, S Bretaud, Y Huang, E Lin, S Gu. Dissociation of food and opiate preference by a genetic mutation in zebrafish. Genes, brain, and behavior. vol 5. issue 7. 2006-12-20. PMID:17010096. |
these studies demonstrate that zebrafish display measurable preference behavior for reward and show that the preference for natural reward and addictive drug is dissociable by a single-gene mutation that alters subregions of brain monoamine neurotransmitter systems. |
2006-12-20 |
2023-08-12 |
zebrafish |
| Wolfgang Sommer, Petri Hyytiä, Kalervo Kiianma. The alcohol-preferring AA and alcohol-avoiding ANA rats: neurobiology of the regulation of alcohol drinking. Addiction biology. vol 11. issue 3-4. 2006-12-19. PMID:16961760. |
most early work evaluated functioning of the major neurotransmitter systems implicated in drug reward in the lines. |
2006-12-19 |
2023-08-12 |
rat |
| Ying Jin, Dafang Chen, Yonghua Hu, Song Guo, Hongqiang Sun, Aili Lu, Xiaoyan Zhang, Lingsong L. Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males. The international journal of neuropsychopharmacology. vol 9. issue 5. 2006-12-11. PMID:16207390. |
monoamine oxidase (mao) is a critical metabolic enzyme of dopamine, which is a key neurotransmitter of the mesolimbic reward pathway in the human brain. |
2006-12-11 |
2023-08-12 |
human |
| Peter Kirsch, Martin Reuter, Daniela Mier, Tina Lonsdorf, Rudolf Stark, Bernd Gallhofer, Dieter Vaitl, Jürgen Henni. Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901644. |
dopamine is known as the main neurotransmitter modulating the activation of the reward system of the brain. |
2006-10-24 |
2023-08-12 |
human |
| R de la Fuente-Fernández, S Lidstone, A J Stoess. Placebo effect and dopamine release. Journal of neural transmission. Supplementum. issue 70. 2006-10-24. PMID:17017561. |
in addition, as dopamine is the major neurotransmitter in the reward circuitry, the model predicts that the release of dopamine in the ventral striatum could be involved in mediating placebo responses not only in parkinson's but also in other medical conditions. |
2006-10-24 |
2023-08-12 |
Not clear |
| Xinmin Xie, Tara L Crowder, Akihiro Yamanaka, Stephen R Morairty, Robin D Lewinter, Takeshi Sakurai, Thomas S Kilduf. GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus. The Journal of physiology. vol 574. issue Pt 2. 2006-09-18. PMID:16627567. |
hypocretin/orexin (hcrt) is a critical neurotransmitter for the maintenance of wakefulness and has been implicated in several other functions, including energy metabolism and reward. |
2006-09-18 |
2023-08-12 |
mouse |
| Armando Salinas, Jennifer D Wilde, Regina E Maldv. Ethanol enhancement of cocaine- and amphetamine-regulated transcript mRNA and peptide expression in the nucleus accumbens. Journal of neurochemistry. vol 97. issue 2. 2006-06-08. PMID:16539670. |
cocaine- and amphetamine-regulated transcript (cart) is a peptide neurotransmitter that has been implicated in drug reward and reinforcement. |
2006-06-08 |
2023-08-12 |
rat |
| M L A V Heien, R M Wightma. Phasic dopamine signaling during behavior, reward, and disease states. CNS & neurological disorders drug targets. vol 5. issue 1. 2006-05-22. PMID:16613556. |
the neurotransmitter dopamine is important in reward processing, however its precise modulatory role is still being investigated. |
2006-05-22 |
2023-08-12 |
rat |
| Robert H Grange. Oxygen as a therapy for reducing nicotine withdrawal symptoms. Medical hypotheses. vol 65. issue 6. 2006-01-05. PMID:16002232. |
there is strong evidence that dopamine is the primary neurotransmitter in the reward pathway in addiction. |
2006-01-05 |
2023-08-12 |
Not clear |
| Kenny J Simansk. NIH symposium series: ingestive mechanisms in obesity, substance abuse and mental disorders. Physiology & behavior. vol 86. issue 1-2. 2005-12-15. PMID:16129461. |
the presentations and discussion from this symposium (1) identified changes in neurotransmitter dynamics and gene expression in brain "reward circuits" accompanying learning of behaviors to obtain palatable foods or drugs of abuse; (2) analyzed behavioral findings in animals and humans, and neuroimaging data in humans, supporting treatment with gaba(b) agonists to reduce craving for drugs of abuse and possibly for highly rewarding foods; and (3) used neuroimaging data in humans to establish novel serotonergic targets for normalizing reward processes and impulse control in anorexia nervosa and bulimia. |
2005-12-15 |
2023-08-12 |
human |
| George W Hubert, Michael J Kuha. Colocalization of CART with substance P but not enkephalin in the rat nucleus accumbens. Brain research. vol 1050. issue 1-2. 2005-09-22. PMID:15978559. |
cart peptide is a novel neurotransmitter that, due to its distribution in the brain and its modulation of dopamine systems, may be involved in aspects of reward and drug abuse. |
2005-09-22 |
2023-08-12 |
rat |
| James A Bib. Decoding dopamine signaling. Cell. vol 122. issue 2. 2005-09-20. PMID:16051141. |
dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. |
2005-09-20 |
2023-08-12 |
Not clear |
| Claire Matson Cannon, Mustafa R Bseikr. Is dopamine required for natural reward? Physiology & behavior. vol 81. issue 5. 2004-10-18. PMID:15234179. |
reward is fundamental to the organization of behavior, and the neurotransmitter dopamine (da) is widely recognized to be critical to the neurobiology of reward, learning and addiction. |
2004-10-18 |
2023-08-12 |
mouse |