| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dianne P Figlewicz, Stephen C Benoi. Insulin, leptin, and food reward: update 2008. American journal of physiology. Regulatory, integrative and comparative physiology. vol 296. issue 1. 2009-02-06. PMID:18945945. |
specifically, insulin and leptin can decrease food reward behaviors and modulate the function of neurotransmitter systems and neural circuitry that mediate food reward, i.e., midbrain dopamine and opioidergic pathways. |
2009-02-06 |
2023-08-12 |
Not clear |
| Marta Lomazzi, Paul A Slesinger, Christian Lüsche. Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins. Trends in pharmacological sciences. vol 29. issue 11. 2009-01-30. PMID:18790542. |
recent studies indicate that rgs proteins also modulate the coupling efficiency between gamma-aminobutyric acid type b (gaba(b)) receptors and girk channels in dopamine neurons of the ventral tegmental area (vta), the initial target for addictive drugs in the brain reward pathway. |
2009-01-30 |
2023-08-12 |
Not clear |
| Adrie W Bruijnzeel, Athina Marko. Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats. Brain research. vol 1058. issue 1-2. 2009-01-26. PMID:16126181. |
decreased sensitivity to the effects of dopamine d1-like, but not d2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats. |
2009-01-26 |
2023-08-12 |
rat |
| Adrie W Bruijnzeel, Athina Marko. Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats. Brain research. vol 1058. issue 1-2. 2009-01-26. PMID:16126181. |
previous studies showed that systemic administration of dopamine d1- or d2-like receptor antagonists induced elevations in brain reward thresholds in drug-free rats, indicative of a decrease in brain reward function. |
2009-01-26 |
2023-08-12 |
rat |
| S L Borgland, E Storm, A Bonc. Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons. The European journal of neuroscience. vol 28. issue 8. 2009-01-26. PMID:18793323. |
highly relevant to these functions, orexin-containing neurons from the lateral hypothalamus project densely to the ventral tegmental area (vta), which is the origin of dopamine projections implicated in motivation and reward. |
2009-01-26 |
2023-08-12 |
rat |
| M Christopher Newland, Elliott M Paletz, Miranda N Ree. Methylmercury and nutrition: adult effects of fetal exposure in experimental models. Neurotoxicology. vol 29. issue 5. 2009-01-23. PMID:18652843. |
it is hypothesized that altered reward processing, dopamine and gabaergic neurotransmitter systems, and cortical regions associated with choice and perseveration are especially sensitive to developmental mehg at low exposure levels. |
2009-01-23 |
2023-08-12 |
human |
| Masayuki Matsumoto, Okihide Hikosak. Negative motivational control of saccadic eye movement by the lateral habenula. Progress in brain research. vol 171. 2009-01-15. PMID:18718332. |
indeed, dopamine neurons are excited by cues predicting reward and inhibited by cues predicting no-reward. |
2009-01-15 |
2023-08-12 |
Not clear |
| Thomas L Kash, William P Nobis, Robert T Matthews, Danny G Winde. Dopamine enhances fast excitatory synaptic transmission in the extended amygdala by a CRF-R1-dependent process. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 51. 2009-01-12. PMID:19091975. |
the actions of dopamine within these circuits are thought to be important in reward and addiction-related behaviors. |
2009-01-12 |
2023-08-12 |
Not clear |
| Kenneth A Perkins, Caryn Lerman, Amy Grottenthaler, Melinda M Ciccocioppo, Melissa Milanak, Cynthia A Conklin, Andrew W Bergen, Neal L Benowit. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690118. |
dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. |
2008-12-31 |
2023-08-12 |
Not clear |
| Kenneth A Perkins, Caryn Lerman, Amy Grottenthaler, Melinda M Ciccocioppo, Melissa Milanak, Cynthia A Conklin, Andrew W Bergen, Neal L Benowit. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690118. |
we explored associations of gene variants in the dopamine, opioid, and serotonin pathways with smoking reward ('liking') and reinforcement (latency to first puff and total puffs) as a function of negative mood and expected versus actual nicotine content of the cigarette. |
2008-12-31 |
2023-08-12 |
Not clear |
| C von der Goltz, F Kiefe. [Learning and memory in the pathogenesis of addiction]. Der Nervenarzt. vol 79. issue 9. 2008-12-30. PMID:18661117. |
in the focus of attention are basic mechanisms involving dopamine, glutamate, and their cellular and molecular targets leading to drug-induced synaptic alterations in the mesolimbic reward system. |
2008-12-30 |
2023-08-12 |
Not clear |
| Wolfram Schultz, Kerstin Preuschoff, Colin Camerer, Ming Hsu, Christopher D Fiorillo, Philippe N Tobler, Peter Bossaert. Explicit neural signals reflecting reward uncertainty. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 363. issue 1511. 2008-12-17. PMID:18829433. |
behavioural neurophysiological studies on dopamine neurons revealed a risk signal, which covaried with the standard deviation or variance of the magnitude of juice rewards and occurred separately from reward value coding. |
2008-12-17 |
2023-08-12 |
human |
| Kozue Aoki, Kumiko Kosakai, Masami Yoshin. Monoaminergic modulation of the Na+-activated K+ channel in Kenyon cells isolated from the mushroom body of the cricket (Gryllus bimaculatus) brain. Journal of neurophysiology. vol 100. issue 3. 2008-12-12. PMID:18550722. |
recent studies have suggested that octopamine (oa) and dopamine (da) play important roles in mediating the reward and punishment signals, respectively, in olfactory learning in insect. |
2008-12-12 |
2023-08-12 |
cricket |
| Eric Ch Wolters, Ysbrand D van der Werf, Odile A van den Heuve. Parkinson's disease-related disorders in the impulsive-compulsive spectrum. Journal of neurology. vol 255 Suppl 5. 2008-12-12. PMID:18787882. |
these disorders comprise dopamine deficiency syndrome (with immediate reward seeking behaviour), dopamine dependency syndrome (with addictive behaviour), dopamine dysregulation syndrome (with both addictive behaviour and stereotyped behaviour) and impulse control disorders (such as pathological gambling, compulsive shopping, binge eating and hypersexuality). |
2008-12-12 |
2023-08-12 |
Not clear |
| A Nessa, S A Latif, N I Siddiqui, M A Hussain, M A Hossai. Drug abuse and addiction. Mymensingh medical journal : MMJ. vol 17. issue 2. 2008-12-05. PMID:18626465. |
almost all addictive drugs over stimulate the reward system of the brain, flooding it with the neurotransmitter dopamine. |
2008-12-05 |
2023-08-12 |
Not clear |
| Bronson E Oosterhuis, K Steven LaForge, Dmitri Proudnikov, Ann Ho, David A Nielsen, Robert Gianotti, Sandra Barral, Derek Gordon, Suzanne M Leal, Jurg Ott, Mary Jeanne Kree. Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18270997. |
catechol-o-methyltransferase (comt) catalyzes the breakdown of catechol neurotransmitters, including dopamine, which plays a prominent role in drug reward. |
2008-12-04 |
2023-08-12 |
human |
| N Benturquia, T Le Marec, J-M Scherrmann, F Nobl. Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward. Neuroscience. vol 155. issue 2. 2008-12-03. PMID:18571333. |
effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward. |
2008-12-03 |
2023-08-12 |
mouse |
| George F Koob, Michel Le Moa. Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 363. issue 1507. 2008-11-17. PMID:18653439. |
specific neurochemical elements in these structures include not only decreases in reward neurotransmission such as dopamine and opioid peptides in the ventral striatum, but also recruitment of brain stress systems such as corticotropin-releasing factor (crf), noradrenaline and dynorphin in the extended amygdala. |
2008-11-17 |
2023-08-12 |
Not clear |
| Michael R Tilley, Howard H G. The effects of methylphenidate on knockin mice with a methylphenidate-resistant dopamine transporter. The Journal of pharmacology and experimental therapeutics. vol 327. issue 2. 2008-11-13. PMID:18698001. |
because methylphenidate is not effective at inhibiting the mutant dopamine transporter, we hypothesized that it would not stimulate locomotor activity or produce reward in the knockin mice. |
2008-11-13 |
2023-08-12 |
mouse |
| Maria Scherma, Leigh V Panlilio, Paola Fadda, Liana Fattore, Islam Gamaleddin, Bernard Le Foll, Zuzana Justinová, Eva Mikics, Jozsef Haller, Julie Medalie, Jessica Stroik, Chanel Barnes, Sevil Yasar, Gianluigi Tanda, Daniele Piomelli, Walter Fratta, Steven R Goldber. Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. The Journal of pharmacology and experimental therapeutics. vol 327. issue 2. 2008-11-13. PMID:18725543. |
furthermore, in vivo microdialysis showed that urb597 reduced nicotine-induced dopamine elevations in the nucleus accumbens shell, the terminal area of the brain's mesolimbic reward system. |
2008-11-13 |
2023-08-12 |
rat |