| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raffaella Isola, Hailin Zhang, Gopi A Tejwani, Norton H Neff, Maria Hadjiconstantino. Acute nicotine changes dynorphin and prodynorphin mRNA in the striatum. Psychopharmacology. vol 201. issue 4. 2009-04-01. PMID:18807250. |
nicotine displays rewarding and aversive effects, and while dopamine has been linked with nicotine's reward, the neurotransmitter(s) involved with aversion remains speculative. |
2009-04-01 |
2023-08-12 |
Not clear |
| Thomas C Jhou, Howard L Fields, Mark G Baxter, Clifford B Saper, Peter C Hollan. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron. vol 61. issue 5. 2009-04-01. PMID:19285474. |
we show that neurons in the recently identified gabaergic rostromedial tegmental nucleus (rmtg), which receive a major lhb input, project heavily to midbrain dopamine neurons, and show phasic activations and/or fos induction after aversive stimuli (footshocks, shock-predictive cues, food deprivation, or reward omission) and inhibitions after rewards or reward-predictive stimuli. |
2009-04-01 |
2023-08-12 |
Not clear |
| Thomas C Jhou, Howard L Fields, Mark G Baxter, Clifford B Saper, Peter C Hollan. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron. vol 61. issue 5. 2009-04-01. PMID:19285474. |
these findings suggest that aversive inputs from widespread brain regions and stimulus modalities converge onto the rmtg, which opposes reward and motor-activating functions of midbrain dopamine neurons. |
2009-04-01 |
2023-08-12 |
Not clear |
| Roy A Wis. Dopamine and reward: the anhedonia hypothesis 30 years on. Neurotoxicity research. vol 14. issue 2-3. 2009-03-31. PMID:19073424. |
dopamine and reward: the anhedonia hypothesis 30 years on. |
2009-03-31 |
2023-08-12 |
Not clear |
| Roy A Wis. Dopamine and reward: the anhedonia hypothesis 30 years on. Neurotoxicity research. vol 14. issue 2-3. 2009-03-31. PMID:19073424. |
the anhedonia hypothesis--that brain dopamine plays a critical role in the subjective pleasure associated with positive rewards--was intended to draw the attention of psychiatrists to the growing evidence that dopamine plays a critical role in the objective reinforcement and incentive motivation associated with food and water, brain stimulation reward, and psychomotor stimulant and opiate reward. |
2009-03-31 |
2023-08-12 |
Not clear |
| Teresa R Franklin, Falk W Lohoff, Ze Wang, Nathan Sciortino, Derek Harper, Yin Li, Will Jens, Jeffrey Cruz, Kyle Kampman, Ron Ehrman, Wade Berrettini, John A Detre, Charles P O'Brien, Anna Rose Childres. DAT genotype modulates brain and behavioral responses elicited by cigarette cues. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 3. 2009-03-30. PMID:18704100. |
as dopamine (da) is critical for reward and its predictive signals, genetically driven variation in da transmission may account for the observed differences. |
2009-03-30 |
2023-08-12 |
Not clear |
| Sabrina Winter, Marco Dieckmann, Kerstin Schwab. Dopamine in the prefrontal cortex regulates rats behavioral flexibility to changing reward value. Behavioural brain research. vol 198. issue 1. 2009-03-30. PMID:19041903. |
dopamine in the prefrontal cortex regulates rats behavioral flexibility to changing reward value. |
2009-03-30 |
2023-08-12 |
rat |
| Sabrina Winter, Marco Dieckmann, Kerstin Schwab. Dopamine in the prefrontal cortex regulates rats behavioral flexibility to changing reward value. Behavioural brain research. vol 198. issue 1. 2009-03-30. PMID:19041903. |
prefrontocortical dopamine (da) plays an essential role in the representation of reward value and is implicated in behavioral flexibility. |
2009-03-30 |
2023-08-12 |
rat |
| Julia M Lappin, Suzanne J Reeves, Mitul A Mehta, Alice Egerton, Mark Coulson, Paul M Grasb. Dopamine release in the human striatum: motor and cognitive tasks revisited. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 29. issue 3. 2009-03-23. PMID:19088741. |
striatal dopamine (da) release has been shown during behavioural tasks, but the relative contribution of motor, reward, and cognitive components is unclear. |
2009-03-23 |
2023-08-12 |
human |
| Patryk A Lauren. The emergence of saliency and novelty responses from Reinforcement Learning principles. Neural networks : the official journal of the International Neural Network Society. vol 21. issue 10. 2009-03-03. PMID:18938058. |
predictive reward signal of dopamine neurons. |
2009-03-03 |
2023-08-12 |
Not clear |
| Patryk A Lauren. The emergence of saliency and novelty responses from Reinforcement Learning principles. Neural networks : the official journal of the International Neural Network Society. vol 21. issue 10. 2009-03-03. PMID:18938058. |
predictive reward signal of dopamine neurons. |
2009-03-03 |
2023-08-12 |
Not clear |
| Zhong-Hua Liu, Rick Shin, Satoshi Ikemot. Dual role of medial A10 dopamine neurons in affective encoding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 12. 2009-02-20. PMID:18256592. |
in addition, moderate quinpirole doses that did not lead to conditioned place aversion or disrupt food intake abolished food-conditioned place preference, suggesting that blunting dopamine impulse activity in response to food reward disrupts positive affective encoding in associated external stimuli. |
2009-02-20 |
2023-08-12 |
Not clear |
| Frederick A Schroeder, Krista L Penta, Anouch Matevossian, Sara R Jones, Christine Konradi, Andrew R Tapper, Schahram Akbaria. Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 12. 2009-02-20. PMID:18288092. |
drug-induced activation of dopamine d(1) receptor signaling and inhibition of class i/ii histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. |
2009-02-20 |
2023-08-12 |
mouse |
| Marieke Wichers, Mari Aguilera, Gunter Kenis, Lydia Krabbendam, Inez Myin-Germeys, Nele Jacobs, Frenk Peeters, Catherine Derom, Robert Vlietinck, Ron Mengelers, Philippe Delespaul, Jim van O. The catechol-O-methyl transferase Val158Met polymorphism and experience of reward in the flow of daily life. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 13. 2009-02-19. PMID:17687265. |
genetic variation with functional impact on cortical dopamine tone has a strong influence on reward experience in the flow of daily life. |
2009-02-19 |
2023-08-12 |
human |
| Jose A Crespo, Petra Stöckl, Katja Zorn, Alois Saria, Gerald Zerni. Nucleus accumbens core acetylcholine is preferentially activated during acquisition of drug- vs food-reinforced behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 13. 2009-02-19. PMID:18418362. |
acquisition of drug-reinforced behavior is accompanied by a systematic increase of release of the neurotransmitter acetylcholine (ach) rather than dopamine, the expected prime reward neurotransmitter candidate, in the nucleus accumbens core (acbc), with activation of both muscarinic and nicotinic ach receptors in the acbc by ach volume transmission being necessary for the drug conditioning. |
2009-02-19 |
2023-08-12 |
Not clear |
| Michael R Tilley, Brian O'Neill, Dawn D Han, Howard H G. Cocaine does not produce reward in absence of dopamine transporter inhibition. Neuroreport. vol 20. issue 1. 2009-02-19. PMID:18987557. |
cocaine does not produce reward in absence of dopamine transporter inhibition. |
2009-02-19 |
2023-08-12 |
mouse |
| Michael R Tilley, Brian O'Neill, Dawn D Han, Howard H G. Cocaine does not produce reward in absence of dopamine transporter inhibition. Neuroreport. vol 20. issue 1. 2009-02-19. PMID:18987557. |
we have previously reported that knockin mice with a cocaine-insensitive dopamine transporter (dat-ci mice) do not experience cocaine reward, as measured by conditioned place preference. |
2009-02-19 |
2023-08-12 |
mouse |
| Taku Nagai, Toshitaka Nabeshima, Kiyofumi Yamad. Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1. Journal of pharmacological sciences. vol 108. issue 4. 2009-02-19. PMID:19098386. |
we show that the tissue plasminogen activator (tpa) - plasmin system regulates nicotine-induced reward and dopamine release in the nucleus accumbens (nac) by activating proteinase-activated receptor 1 (par(1)). |
2009-02-19 |
2023-08-12 |
mouse |
| Jean-Claude Dreher, Philip Kohn, Bhaskar Kolachana, Daniel R Weinberger, Karen Faith Berma. Variation in dopamine genes influences responsivity of the human reward system. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 2. 2009-02-13. PMID:19104049. |
variation in dopamine genes influences responsivity of the human reward system. |
2009-02-13 |
2023-08-12 |
human |
| Jean-Claude Dreher, Philip Kohn, Bhaskar Kolachana, Daniel R Weinberger, Karen Faith Berma. Variation in dopamine genes influences responsivity of the human reward system. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 2. 2009-02-13. PMID:19104049. |
moreover, an interaction between the comt and dat1 genes was found in the ventral striatum and lateral prefrontal cortex during reward anticipation and in the lateral prefrontal and orbitofrontal cortices as well as in the midbrain at the time of reward delivery, with carriers of the dat1 9-repeat allele and comt met/met allele exhibiting the highest activation, presumably reflecting functional change consequent to higher synaptic dopamine availability. |
2009-02-13 |
2023-08-12 |
human |