| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lynette C Daws, Malcolm J Avison, Sabrina D Robertson, Kevin D Niswender, Aurelio Galli, Christine Saunder. Insulin signaling and addiction. Neuropharmacology. vol 61. issue 7. 2012-01-27. PMID:21420985. |
the central role of dopamine (da) in encoding reward and in attaching salience to external environmental cues is well recognized. |
2012-01-27 |
2023-08-12 |
monkey |
| S Carnell, C Gibson, L Benson, C N Ochner, A Geliebte. Neuroimaging and obesity: current knowledge and future directions. Obesity reviews : an official journal of the International Association for the Study of Obesity. vol 13. issue 1. 2012-01-27. PMID:21902800. |
positron emission tomography (pet), functional magnetic resonance imaging (fmri) and magnetic resonance imaging (mri) studies examining responses to food intake and food cues, dopamine function and brain volume in lean vs. obese individuals are now beginning to coalesce in identifying irregularities in a range of regions implicated in reward (e.g. |
2012-01-27 |
2023-08-12 |
Not clear |
| Eonyoung Park, Ciro Iaccarino, Jiwon Lee, Ilmin Kwon, Sun Mi Baik, Myungjin Kim, Jae Young Seong, Gi Hoon Son, Emiliana Borrelli, Kyungjin Ki. Regulatory roles of heterogeneous nuclear ribonucleoprotein M and Nova-1 protein in alternative splicing of dopamine D2 receptor pre-mRNA. The Journal of biological chemistry. vol 286. issue 28. 2012-01-24. PMID:21622564. |
the dopamine d2 receptor (d2r) plays a crucial role in the regulation of diverse key physiological functions, including motor control, reward, learning, and memory. |
2012-01-24 |
2023-08-12 |
Not clear |
| Lauren V Riter. Pleasure seeking and birdsong. Neuroscience and biobehavioral reviews. vol 35. issue 9. 2012-01-19. PMID:21251924. |
dopamine and opioid neuropeptides play a primary role in reward seeking and sensory pleasure. |
2012-01-19 |
2023-08-12 |
Not clear |
| Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
although the mesolimbic dopamine hypothesis is the most influential theory of nicotine reward and reinforcement, there has been a consensus that other neurotransmitter systems contribute to the addictive properties of nicotine as well. |
2012-01-18 |
2023-08-12 |
Not clear |
| V A Ramchandani, J Umhau, F J Pavon, V Ruiz-Velasco, W Margas, H Sun, R Damadzic, R Eskay, M Schoor, A Thorsell, M L Schwandt, W H Sommer, D T George, L H Parsons, P Herscovitch, D Hommer, M Heili. A genetic determinant of the striatal dopamine response to alcohol in men. Molecular psychiatry. vol 16. issue 8. 2011-12-19. PMID:20479755. |
dopamine release in ventral striatum is a common element of drug reward, but alcohol has an unusually complex pharmacology, and humans vary greatly in their alcohol responses. |
2011-12-19 |
2023-08-12 |
mouse |
| V A Ramchandani, J Umhau, F J Pavon, V Ruiz-Velasco, W Margas, H Sun, R Damadzic, R Eskay, M Schoor, A Thorsell, M L Schwandt, W H Sommer, D T George, L H Parsons, P Herscovitch, D Hommer, M Heili. A genetic determinant of the striatal dopamine response to alcohol in men. Molecular psychiatry. vol 16. issue 8. 2011-12-19. PMID:20479755. |
oprm1 a118g variation is a genetic determinant of dopamine responses to alcohol, a mechanism by which it likely modulates alcohol reward. |
2011-12-19 |
2023-08-12 |
mouse |
| Anna M Lee, Robert O Messin. Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 38. 2011-12-12. PMID:21911393. |
protein kinase c epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. |
2011-12-12 |
2023-08-12 |
mouse |
| Charles L Pickens, Donna J Cal. Alcohol reward, dopamine depletion, and GDNF. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 42. 2011-12-08. PMID:22016515. |
alcohol reward, dopamine depletion, and gdnf. |
2011-12-08 |
2023-08-12 |
Not clear |
| Noah Meyers, Stephen Fromm, David A Luckenbaugh, Wayne C Drevets, Gregor Hasle. Neural correlates of sleepiness induced by catecholamine depletion. Psychiatry research. vol 194. issue 1. 2011-12-06. PMID:21872452. |
this study suggests that the association between dopamine depletion and sleepiness is independent of the brain reward system and the risk for depression. |
2011-12-06 |
2023-08-12 |
human |
| Andrew Evan. Dopamine agonist-induced substance addiction: the next piece of the puzzle. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:20980151. |
the recent recognition of a range of "behavioural addictions" that are linked to dopamine agonist use has highlighted the role of dopamine in brain reward function and addiction disorders in general. |
2011-12-05 |
2023-08-12 |
Not clear |
| Eva M Marco, Walter Adriani, Lucia A Ruocco, Rossella Canese, Adolfo G Sadile, Giovanni Laviol. Neurobehavioral adaptations to methylphenidate: the issue of early adolescent exposure. Neuroscience and biobehavioral reviews. vol 35. issue 8. 2011-12-01. PMID:21376076. |
moreover, adolescent exposure to mph seems to provoke persistent neurobehavioral consequences: long-term modulation of self-control abilities, decreased sensitivity to natural and drug reward, enhanced stress-induced emotionality, together with an enhanced cortical control over sub-cortical dopamine systems and an enduring up-regulation of htr7 gene expression within the nucleus accumbens (nacc). |
2011-12-01 |
2023-08-12 |
human |
| Anna R Moore, Wen-Liang Zhou, Evgeniy S Potapenko, Eun-Ji Kim, Srdjan D Anti. Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons. Brain research. vol 1370. 2011-11-23. PMID:21059342. |
in response to food reward and other pertinent events, midbrain dopaminergic neurons fire short bursts of action potentials causing a phasic release of dopamine in the prefrontal cortex (rapid and transient increases in cortical dopamine concentration). |
2011-11-23 |
2023-08-12 |
rat |
| Jessica B Lennington, Sara Pope, Anna E Goodheart, Linda Drozdowicz, Stephen B Daniels, John D Salamone, Joanne C Conove. Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 37. 2011-11-22. PMID:21917791. |
midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone. |
2011-11-22 |
2023-08-12 |
mouse |
| Jessica B Lennington, Sara Pope, Anna E Goodheart, Linda Drozdowicz, Stephen B Daniels, John D Salamone, Joanne C Conove. Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 37. 2011-11-22. PMID:21917791. |
together, these results reveal that dopamine signaling in the svz originates from a population of midbrain neurons more typically associated with motivational and reward processing. |
2011-11-22 |
2023-08-12 |
mouse |
| Zhongchi Luo, Nora D Volkow, Nathaniel Heintz, Yingtian Pan, Congwu D. Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 37. 2011-11-22. PMID:21917801. |
both dopamine d1 and d2 receptors are involved in cocaine's reward but the dynamic downstream consequences of cocaine effects in striatum are not fully understood. |
2011-11-22 |
2023-08-12 |
mouse |
| Sadia Oreland, Karita Raudkivi, Lars Oreland, Jaanus Harro, Lotta Arborelius, Ingrid Nylande. Ethanol-induced effects on the dopamine and serotonin systems in adult Wistar rats are dependent on early-life experiences. Brain research. vol 1405. 2011-11-15. PMID:21741625. |
tissue levels of dopamine, 5-hydroxytryptamine (5-ht) and their metabolites were measured in brain areas that have been implicated in reward and addiction processes. |
2011-11-15 |
2023-08-12 |
rat |
| Stephanie F Bishop, Nicole M Lauzon, Melanie Bechard, Shervin Gholizadeh, Steven R Laviolett. NMDA receptor hypofunction in the prelimbic cortex increases sensitivity to the rewarding properties of opiates via dopaminergic and amygdalar substrates. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 1. 2011-11-14. PMID:20392811. |
this reward potentiation was dose dependently blocked by coadministration of dopamine d1 or d2 receptor antagonists and by blockade of presynaptic glut release. |
2011-11-14 |
2023-08-12 |
Not clear |
| C A Fontes-Ribeiro, E Marques, F C Pereira, A P Silva, T R A Maced. May exercise prevent addiction? Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886560. |
amphetamines exert their persistent addictive effects by activating brain's reward pathways, perhaps through the release of dopamine in the nucleus accumbens (and/or in other places). |
2011-11-10 |
2023-08-12 |
rat |
| Scott D Philibin, Adan Hernandez, David W Self, James A Bib. Striatal signal transduction and drug addiction. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21960960. |
dopamine receptors important for reward serve as principle targets of drugs abuse, which interact with glutamate receptor signaling critical for reward learning. |
2011-11-10 |
2023-08-12 |
Not clear |