| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanso. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Molecular psychiatry. vol 16. issue 11. 2012-03-05. PMID:20856250. |
motivation deficit in adhd is associated with dysfunction of the dopamine reward pathway. |
2012-03-05 |
2023-08-12 |
human |
| N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanso. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Molecular psychiatry. vol 16. issue 11. 2012-03-05. PMID:20856250. |
using positron emission tomography (pet), we showed decreased function in the brain dopamine reward pathway in adults with adhd, which, we hypothesized, could underlie the motivation deficits in this disorder. |
2012-03-05 |
2023-08-12 |
human |
| N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanso. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Molecular psychiatry. vol 16. issue 11. 2012-03-05. PMID:20856250. |
to evaluate this hypothesis, we performed secondary analyses to assess the correlation between the pet measures of dopamine d2/d3 receptor and dopamine transporter availability (obtained with [(11)c]raclopride and [(11)c]cocaine, respectively) in the dopamine reward pathway (midbrain and nucleus accumbens) and a surrogate measure of trait motivation (assessed using the achievement scale on the multidimensional personality questionnaire or mpq) in 45 adhd participants and 41 controls. |
2012-03-05 |
2023-08-12 |
human |
| N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanso. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Molecular psychiatry. vol 16. issue 11. 2012-03-05. PMID:20856250. |
these findings provide evidence that disruption of the dopamine reward pathway is associated with motivation deficits in adhd adults, which may contribute to attention deficits and supports the use of therapeutic interventions to enhance motivation in adhd. |
2012-03-05 |
2023-08-12 |
human |
| Dimitrios Kapogiannis, Eric Mooshagian, Paul Campion, Jordan Grafman, Trelawny J Zimmermann, Kelsey C Ladt, Eric M Wasserman. Reward processing abnormalities in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 26. issue 8. 2012-02-29. PMID:21538525. |
these results provide evidence that modulation of motor cortex inhibition by reward is mediated by dopamine signaling and that the physiological state of the motor cortex changes with risk-taking tendency in patients on pramipexole. |
2012-02-29 |
2023-08-12 |
Not clear |
| Masayuki Matsumoto, Okihide Hikosak. Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism. PloS one. vol 6. issue 10. 2012-02-28. PMID:22039537. |
neurons in the lhb are excited by unpleasant events such as reward omission and aversive stimuli, and transmit these signals to midbrain dopamine neurons which are involved in learning and motivation. |
2012-02-28 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
transient activation of midbrain dopamine neurons by reward risk. |
2012-02-27 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
dopamine neurons of the ventral midbrain are activated transiently following stimuli that predict future reward. |
2012-02-27 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
behavior is also influenced by reward uncertainty, or risk, but it is not known whether the transient response of dopamine neurons is sensitive to reward risk. |
2012-02-27 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
in a pavlovian task, in which the neuronal responses to each stimulus could be measured in isolation, it was found that dopamine neurons were more strongly activated by the stimulus associated with reward risk. |
2012-02-27 |
2023-08-12 |
monkey |
| Arnaud L Lalive, Uwe Rudolph, Christian Lüscher, Kelly R Ta. Is there a way to curb benzodiazepine addiction? Swiss medical weekly. vol 141. 2012-02-21. PMID:22012428. |
these results have identified the mechanisms underlying the activation of midbrain dopamine neurons by benzodiazepines, and how these drugs can hijack the mesocorticolimbic reward system. |
2012-02-21 |
2023-08-12 |
Not clear |
| Jan Kassubek, Birgit Abler, Elmar H Pinkhard. Neural reward processing under dopamine agonists: imaging. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21762926. |
neural reward processing under dopamine agonists: imaging. |
2012-02-16 |
2023-08-12 |
Not clear |
| Jan Kassubek, Birgit Abler, Elmar H Pinkhard. Neural reward processing under dopamine agonists: imaging. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21762926. |
icds together with punding are described within the entity of dopamine dysregulation syndrome along with immediate reward seeking and addictive behaviors. |
2012-02-16 |
2023-08-12 |
Not clear |
| Luke D Smillie, Andrew J Cooper, Alan D Pickerin. Individual differences in reward-prediction-error: extraversion and feedback-related negativity. Social cognitive and affective neuroscience. vol 6. issue 5. 2012-02-15. PMID:20855297. |
results have broad relevance to neuroscience and personality research concerning reward processing and dopamine function. |
2012-02-15 |
2023-08-12 |
human |
| L Strathear. Maternal neglect: oxytocin, dopamine and the neurobiology of attachment. Journal of neuroendocrinology. vol 23. issue 11. 2012-02-10. PMID:21951160. |
for example, in insecure/dismissing attachment, which may be associated with emotional neglect, we see reduced activation of the mesocorticolimbic dopamine reward system in response to infant face cues, as well as decreased peripheral oxytocin response to mother-infant contact. |
2012-02-10 |
2023-08-12 |
human |
| Nicholas W Simon, Karienn S Montgomery, Blanca S Beas, Marci R Mitchell, Candi L LaSarge, Ian A Mendez, Cristina Bañuelos, Colin M Vokes, Aaron B Taylor, Rebecca P Haberman, Jennifer L Bizon, Barry Setlo. Dopaminergic modulation of risky decision-making. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 48. 2012-02-09. PMID:22131407. |
these data strongly implicate dopamine signaling in prefrontal cortical-striatal circuitry in modulating decision-making processes involving integration of reward information with risks of adverse consequences. |
2012-02-09 |
2023-08-12 |
rat |
| Benjamin T Saunders, Jocelyn M Richar. Shedding light on the role of ventral tegmental area dopamine in reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 50. 2012-02-09. PMID:22171025. |
shedding light on the role of ventral tegmental area dopamine in reward. |
2012-02-09 |
2023-08-12 |
Not clear |
| Guido K W Frank, Jeremy R Reynolds, Megan E Shott, Randall C O'Reill. Altered temporal difference learning in bulimia nervosa. Biological psychiatry. vol 70. issue 8. 2012-01-31. PMID:21718969. |
recent animal literature suggests that binge eating is associated with altered brain dopamine (da) reward function. |
2012-01-31 |
2023-08-12 |
Not clear |
| Katja N Spreckelmeyer, Michael Paulzen, Mardjan Raptis, Thomas Baltus, Sabrina Schaffrath, Julia Van Waesberghe, Magdalena M Zalewski, Frank Rösch, Ingo Vernaleken, Wolfgang M Schäfer, Gerhard Gründe. Opiate-induced dopamine release is modulated by severity of alcohol dependence: an [(18)F]fallypride positron emission tomography study. Biological psychiatry. vol 70. issue 8. 2012-01-31. PMID:21802658. |
specifically, alcohol-induced release of β-endorphins stimulates μ-opioid receptors (mors), which is believed to cause dopamine release in the brain reward system. |
2012-01-31 |
2023-08-12 |
human |
| Katja N Spreckelmeyer, Michael Paulzen, Mardjan Raptis, Thomas Baltus, Sabrina Schaffrath, Julia Van Waesberghe, Magdalena M Zalewski, Frank Rösch, Ingo Vernaleken, Wolfgang M Schäfer, Gerhard Gründe. Opiate-induced dopamine release is modulated by severity of alcohol dependence: an [(18)F]fallypride positron emission tomography study. Biological psychiatry. vol 70. issue 8. 2012-01-31. PMID:21802658. |
in the present study, a single dose of the mor agonist remifentanil was administered in detoxified alcohol-dependent patients and healthy control subjects to mimic the β-endorphin-releasing properties of ethanol and to assess the effects of direct mor stimulation on dopamine release in the mesolimbic reward system. |
2012-01-31 |
2023-08-12 |
human |