| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingjing Yang, Hongjuan Wang, Huan Chen, Hongwei Hou, Qingyuan H. The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review. Heliyon. vol 10. issue 12. 2024-07-18. PMID:39021905. |
nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding effect or satisfaction. |
2024-07-18 |
2024-07-20 |
Not clear |
| Sarah Warren Gooding, Elinor Lewis, Christine Chau, Suhail Sandhu, Julianna Glienke, Jennifer L Whistle. Nucleus accumbens sub-regions experience distinct dopamine release responses following acute and chronic morphine exposure. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005415. |
it is well established that dopamine neurons of the ventral tegmental area (vta) play a critical role in reward and aversion as well as pathologies including drug dependence and addiction. |
2024-07-15 |
2024-07-18 |
mouse |
| Mohammad Navid Ebrahimi, Mohammad Banazadeh, Zahra Alitaneh, Ali Jaafari Suha, Ali Esmaeili, Behnam Hasannejad-Asl, Ali Siahposht-Khachaki, Amin Hasanshahi, Saeid Bagheri-Mohammad. The distribution of neurotransmitters in the brain circuitry: mesolimbic pathway and addiction. Physiology & behavior. 2024-07-14. PMID:39004195. |
while the role of some reward circuits, like the cerebral dopamine (da)/glutamate (glu)/gamma aminobutyric acid (gaba)ergic pathways, in drug reward, is well known, new research using molecular-based methods has shown functional alterations throughout the reward circuitry that contribute to various aspects of addiction, including craving and relapse. |
2024-07-14 |
2024-07-18 |
human |
| Ian Cone, Claudia Clopath, Harel Z Shouva. Learning to express reward prediction error-like dopaminergic activity requires plastic representations of time. Nature communications. vol 15. issue 1. 2024-07-12. PMID:38997276. |
we propose an alternate framework to describe dopamine signaling in the brain, flex (flexibly learned errors in expected reward). |
2024-07-12 |
2024-07-15 |
Not clear |
| Divya Soni, Shubham Upadhayay, Maanvi Dhureja, Richmond Arthur, Puneet Kuma. Crosstalk between gut-brain axis: unveiling the mysteries of gut ROS in progression of Parkinson's disease. Inflammopharmacology. 2024-07-11. PMID:38992324. |
research has shown that eating food activates the reward system and releases dopamine (da), establishing a link between the peripheral and central nervous system. |
2024-07-11 |
2024-07-14 |
Not clear |
| Cristina Banuelos, Kasey Creswell, Catherine Walsh, Stephen B Manuck, Peter J Gianaros, Timothy Dennis Verstyne. D2 dopamine receptor expression, reactivity to rewards, and reinforcement learning in a complex value-based decision-making task. Social cognitive and affective neuroscience. 2024-07-11. PMID:38988197. |
this effective sensitivity to different reward feedback interacts with phasic dopamine levels to determine the effectiveness of learning, particularly in dynamic feedback situations where frequency and magnitude of rewards need to be integrated over time to make optimal decisions. |
2024-07-11 |
2024-07-13 |
human |
| Greatness O Olaitan, Mallikarjunarao Ganesana, Andrew Strohman, Wendy J Lynch, Wynn Legon, B Jill Vento. Focused Ultrasound Modulates Dopamine in a Mesolimbic Reward Circuit. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979318. |
focused ultrasound modulates dopamine in a mesolimbic reward circuit. |
2024-07-09 |
2024-07-12 |
Not clear |
| Greatness O Olaitan, Mallikarjunarao Ganesana, Andrew Strohman, Wendy J Lynch, Wynn Legon, B Jill Vento. Focused Ultrasound Modulates Dopamine in a Mesolimbic Reward Circuit. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979318. |
dopamine is a neurotransmitter that plays a significant role in reward and motivation. |
2024-07-09 |
2024-07-12 |
Not clear |
| Chih-Ting Wu, Diego Gonzalez Magaña, Jacob Roshgadol, Lin Tian, Karen K Rya. Dietary protein restriction diminishes sucrose reward and reduces sucrose-evoked mesolimbic dopamine signaling. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979357. |
dietary protein restriction diminishes sucrose reward and reduces sucrose-evoked mesolimbic dopamine signaling. |
2024-07-09 |
2024-07-12 |
Not clear |
| Sarah Witley, Christian E Edvardsson, Cajsa Aranäs, Maximilian Tufvesson-Alm, Darta Stalberga, Henrik Green, Jesper Vestlund, Elisabet Jerlha. Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents. Translational psychiatry. vol 14. issue 1. 2024-07-04. PMID:38965230. |
in these alcohol-consuming male rats, repeated dag treatment causes higher levels of dopamine metabolites in the ventral tegmental area, an area central to reward processing. |
2024-07-04 |
2024-07-08 |
rat |
| Sarah Witley, Christian E Edvardsson, Cajsa Aranäs, Maximilian Tufvesson-Alm, Darta Stalberga, Henrik Green, Jesper Vestlund, Elisabet Jerlha. Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents. Translational psychiatry. vol 14. issue 1. 2024-07-04. PMID:38965230. |
the role of dag in reward processing is further supported as dag prevents alcohol-induced locomotor stimulation, reward in the conditioned place preference paradigm, and dopamine release in the nucleus accumbens in male rodents. |
2024-07-04 |
2024-07-08 |
rat |
| E J Hird, A Slanina-Davies, G Lewis, M Hamer, J P Roise. From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational psychiatry. vol 14. issue 1. 2024-07-03. PMID:38961071. |
depression is associated with disruptions to several closely related neural and cognitive processes, including dopamine transmission, fronto-striatal brain activity and connectivity, reward processing and motivation. |
2024-07-03 |
2024-07-08 |
Not clear |
| E J Hird, A Slanina-Davies, G Lewis, M Hamer, J P Roise. From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational psychiatry. vol 14. issue 1. 2024-07-03. PMID:38961071. |
inflammation is known to reduce dopamine transmission, which in turn is strongly implicated in effort-based decision making for reward. |
2024-07-03 |
2024-07-08 |
Not clear |
| E J Hird, A Slanina-Davies, G Lewis, M Hamer, J P Roise. From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational psychiatry. vol 14. issue 1. 2024-07-03. PMID:38961071. |
drawing on a broad range of research in humans and animals, we propose that by reducing inflammation and boosting dopamine transmission, with consequent effects on effort-based decision making for reward, exercise initially specifically improves 'interest-activity' symptoms of depression-namely anhedonia, fatigue and subjective cognitive impairment - by increasing propensity to exert effort. |
2024-07-03 |
2024-07-08 |
Not clear |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
the magnitude of dopamine signals elicited by rewarding events and their predictors is updated when reward value changes. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
to investigate this, we trained male rats in a pavlovian-conditioning paradigm and measured dopamine release in the nucleus accumbens core in response to food reward (unconditioned stimulus) and reward-predictive conditioned stimuli (cs), both before and after reward devaluation, induced via either sensory-specific or non-specific satiety. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
we demonstrate that 1) such devaluation reduces cs-induced dopamine release rapidly, without additional pairing of cs with devalued reward, and irrespective of whether the devaluation was sensory-specific or non-specific. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
in contrast, 2) reward devaluation did not decrease food reward-induced dopamine release. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
surprisingly, 3) post-devaluation reconditioning, by additional pairing of cs with devalued reward, rapidly reinstated cs-induced dopamine signals to pre-devaluation levels. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
taken together, we identify distinct, divergent adaptations in dopamine-signal magnitude when reward value is decreased: cs dopamine diminishes but reinstates fast, whereas reward dopamine is resistant to change. |
2024-06-25 |
2024-06-29 |
rat |